Spanish Fly for two - how they affect libido in women and men
Contents Biologically active additive based on an extract obtained from a beetle with a fly (or fly...
Antiviral agent - oligopeptide (histidine - glycine - valine - serine - glycine - histidine - glycine - glutamine - histidine - glycine - valine - histidine - glycine), pharmacologically close to interferon alpha.
Inducer of endogenous interferon synthesis and activator of the NK-killer system. Stimulates recognition and lysis of defective cells by cytotoxic lymphocytes. Effective in infections caused by influenza A and B viruses, hepatitis C, herpes.
It does not have general toxicity, allergenic, mutagenic, carcinogenic, embryotoxic effects and does not affect reproductive function.
An increase in the concentration of interferon is observed 2 hours after the administration of the drug; a high concentration persists (2-2.5 times higher than the usual background) for 6-8 hours with a decrease to the initial values by the end of the day. Increased functional activity of NK-killers is observed within 7 days after drug administration.
Lyophilizate for preparation of a solution for s / c administration in the form of a powder or porous mass, white, odorless; hygroscopic.
1 mg - ampoules (1) - blister packs (1) - cardboard packs.
1 mg - ampoules (2) - blister packs (1) - cardboard packs.
1 mg - ampoules (3) - blister packs (1) - cardboard packs.
1 mg - ampoules (5) - blister packs (1) - cardboard packs.
1 mg - ampoules (10) - blister packs (1) - cardboard packs.
Appoint p / c.
With a frequency of relapses of more than 6 per year and a duration of more than 5 days, 3 injections at a dose of 10 mg with an interval of 1 day are recommended for the first relapse, 1-3 injections of 1 mg each for the next relapse, and 1-3 injections of 0.1 each for the subsequent relapse. mg.
With a recurrence rate of less than 6 per year and a duration of less than 5 days, 3 injections are recommended with an interval of 1 day, 1 mg each, in the next relapse - 1-3 injections of 0.1 mg each.
Before administration, the drug is dissolved in 1 ml of 0.9% sodium chloride solution.
Perhaps: weakness, dizziness, the formation of new elements of a herpetic rash.
The description is up to date 07.08.2014
1 ampoule of the drug contains 1 mg alloferon .
The pharmaceutical product is supplied to pharmacies in the form of a lyophilized powder for the preparation of a solution for subcutaneous administration, placed in ampoules of 1 mg each. Ampoules are fixed in a cassette blister pack made of polymeric materials, 5 or 10 pieces each. The set also includes an ampoule knife in a single copy. A cardboard box contains, as a rule, 2 blisters for 5 ampoules or 1 for 10.
Allokin-Alpha is a pharmaceutical drug that belongs to the group of antiviral agents. The drug is active against viruses , And , the first and second type of virus , (the drug also suppresses oncogenic strains this type of microorganism).
Biologically active substance acting as an active ingredient is alloferon - an oligopeptide that stimulates the production of endogenous interferon fractions and activates natural killer system (natural killers). The component also contributes to the identification and destruction of damaged and non-functioning cells by cytotoxic species. .
Allokin-Alpha is used for subcutaneous administration, after which it quickly penetrates into the systemic circulation and interacts with immunocompetent cells . In the course of clinical studies, it was found that the metabolites of the active component of the pharmaceutical preparation are similar in structural structure to blood plasma proteins, therefore it is difficult to establish the time to reach the maximum concentration, its level.
Within two hours after using the drug, an increase in the level of endogenous compared with the usual background by 2-2.5 times. This amount of protein with immune properties is stored for the next 6-8 hours. Increased quantity natural killers noted for 7 days after a single use of the pharmaceutical preparation.
Side effects in the treatment of this pharmaceutical preparation are quite rare, since the composition of the drug is fully described by the active ingredient. In isolated cases, there may be:
The contents of the ampoule (lyophilized powder) should be dissolved in 1 ml isotonic sodium chloride solution . It is not recommended to use any other solvent, even from the crystalloid group. If conservative therapy consists of several pharmaceutical preparations that must be administered subcutaneously, then it is strictly forbidden to mix medicinal solutions in a syringe. It is necessary to use Allokin-Alpha ready for injection immediately, since over time the therapeutic effect of the drug is lost and its administration will be impractical.
The medicinal solution is administered in the form subcutaneous injection . How to inject subcutaneously should be discussed with qualified medical personnel. Below is the general sequence of actions:
Where to inject is determined by the representative of the medical personnel who performs the manipulation. As a rule, subcutaneous injections are carried out in the upper third of the outer surface of the shoulder, the subscapular region of the back, the anterolateral surface of the thigh, or the lateral surface of the abdomen.
The conservative course of treatment with Allokin-Alpha is determined by the doctor, as it is individual and depends on the disease and the severity of the patient's condition:
Clinically confirmed cases of overdose have not been described.
Care should be taken when combining Allokin-Alpha and drugs groups in complex therapy. Recommended regular diagnostic blood tests with the inevitability of the simultaneous use of these drugs.
Combining Allokin-Alpha with in complex therapy of chronic relapsing form is allowed, since due to the different mechanism of action of the active ingredients of pharmaceuticals, their antiviral effects potentiate each other (the overall therapeutic efficacy is significantly increased).
Released only upon presentation of a prescription form, certified by the signature and seal of the attending physician.
Store ampoules with injection solution in a dry, dark place out of the reach of children at the recommended temperature range of 2 to 8 degrees Celsius.
2 years (it is forbidden to store the finished solution).
At hepatitis B And WITH complex treatment should be carried out no later than the 7th day from the onset of active manifestation of symptoms jaundice :
During the course of a conservative course of treatment, one should refuse to independently drive a car or other potentially life-threatening mechanisms, as there have been isolated cases of dizziness during the use of a pharmaceutical preparation.
The pharmaceutical preparation is practically unique in its kind, since the indications for its use cover a fairly wide range of different viruses, and side effects or adverse effects are observed only in isolated cases. Therefore, analogues of Allokin-Alpha are presented only alloferon .
The use of the drug is strictly contraindicated in pediatric practice (it can be used in complex therapy only after 18 years).
Formally, alcoholic beverages do not interact with the constituent components of the pharmaceutical preparation, however, it is recommended to completely exclude alcohol from the diet during the course of drug treatment. This precaution is explained by the effects that Allokin-Alpha has on the human body.
Under the action of a biologically active substance, the concentration of circulating interferon , and this plasma fraction is quite sensitive to changes in the chemical composition of the blood. Because alcohol-containing drinks can cause unpredictable side effects.
The pharmaceutical preparation should not be used during periods of pregnancy and breastfeeding, since the active component may have adverse effects on the developing child's body, however mutagenic , teratogenic or fetotoxic effects no drug was found in clinical trials.
If during lactation it is not possible to replace the therapeutic effect of the antiviral agent, it is recommended to discuss the issue of interrupting breast milk feeding with a qualified specialist.
The pharmaceutical drug has a good reputation, based on various forums or other Internet resources. The vast majority of people who have been treated with this drug are satisfied. Allokin-Alpha exerts its therapeutic effect within a short period of time and shows really good results, since the active ingredient is extremely active.
Reviews at herpes once again confirm the opinion of patients, especially if you use complex therapy with Allokin-Alpha and Acyclovir , because their action potentiates each other, which greatly increases the productivity of conservative treatment. Unpleasant rashes disappear already on the second or third day after the start of active medical rehabilitation, in contrast to monotherapy with any of the means (a noticeable therapeutic result can sometimes be expected up to two weeks).
Reviews of doctors about Allokin-Alpha are also favorable. Of course, the medical staff of state institutions complains about the price of the drug, but from the point of view of pharmacy, Allokin-Alpha is really unique in its kind. Efficiency rates amaze even people far from medicine: the prevention of dysplasia and cervical cancer is successful in 98 percent of all cases, and the treatment of human papillomavirus - in 96 percent.
The price of Allokin-Alpha 6 ampoules on the territory of the Russian Federation largely depends on the place of purchase of the pharmaceutical product. So Yekaterinburg offers a cost of 3200 rubles, you can buy Allokin-Alpha in Moscow for 3400 rubles, and in Krasnoyarsk the price of the drug ranges from 3500 rubles.
The price of Allokin-Alpha in Ukraine is more stable. In all regions of the country, the average cost of the drug is at the limit of 1000 hryvnia.
Allokin-alpha (por. d / in. 1mg No. 3)
Allokin-alpha powder for subcutaneous injections 1 mg n6
Allokin-alpha powder for subcutaneous injections 1 mg n3
Federal State Institution RKNPK of the Ministry of Health of the Russian Federationshow more
show more
Allokin pierced - HPV was not detected. The gynecologist said, you can live in peace, only periodically checked. But my boyfriend and I were treated together, so 100%.
I also pricked Allokin for herpes. Herpes got very strong. I have tried all kinds of medicines. Some helped, but only temporarily. I pierced the course of Allokin, somewhere for a year there were no rashes. Analyzes show the presence of herpes, but the titers have decreased.
Alexander, you will excuse me, but probably they were not treated correctly, Allokin helped many. Me including. For many years I was tormented by herpes, four or five times a year, I pierced Allokin injections immediately felt better, after a couple of hours the burning sensation and itching stopped. And since September 2018, there has never been a rash.
Treated cervical erosion. Moreover, in the analyzes they found HPV 16/18. The doctor said that complex treatment is needed. I burned the erosion and prescribed injections of Allokin-alpha No. 6 every other day. It pierced as it was supposed to. Three months later, PCR control. HPV was not detected! Very satisfied!!!
Very satisfied! Allokin alfa saved me from HPV. The injections are not painful, there were no difficulties with buying medicine either. One minus, I couldn’t inject myself, I had to go to the clinic every other day
I weighed all the pros and cons, and in the fall I started a course of HPV treatment with Allokin. For me, injections are preferable to pills and ointments, there is more faith in them, and the pills still don’t know how the body will backfire later. Last week I received my results: negative - no virus. So I recommend it, it really works.
Lyophilizate for preparation of a solution for s / c administration in the form of a powder or porous mass, white, odorless; hygroscopic.
1 amp. contains: histidyl-glycyl-valyl-seryl-glycyl-histidyl-glycyl-glutaminyl-histidyl-glycyl-valyl-histidyl-glycine - 1 mg
Release form:
Alloferon is an oligopeptide. The nature of the pharmacological action is most similar to interferon alpha. Alloferon is an effective inducer of the synthesis of endogenous interferons and an activator of the natural killer system, it is able to stimulate the disposition and lysis of defective cells by cytotoxic lymphocytes. The experiments demonstrated high efficiency against infections caused by influenza A and B viruses, hepatitis B and C, herpes types 1 and 2 and human papilloma. Alloferon does not have general toxicity, allergenic properties, mutagenic and carcinogenic effects, does not have an embryotoxic effect and does not affect reproductive function.
It quickly penetrates into the blood, where it interacts with immunocompetent cells, after which the determination of the concentration of Alloferon is difficult due to the close structural similarity of its metabolites with blood serum proteins. An increase in the concentration of interferon was observed 2 hours after the administration of the drug and remained at a high level (2-2.5 times higher than the usual background level) for 6-8 hours, reaching the initial values by the end of the day. Increased functional activity of natural killers was observed within 7 days after drug administration.
The drug is contraindicated during pregnancy and lactation
Contraindicated in childhood.
In some cases, weakness, dizziness, the formation of new elements of the rash (with a herpes infection) are possible.
In the treatment of chronic recurrent genital herpes, it can be prescribed in combination with acyclovir and its derivatives (drugs have different mechanisms of action and complement each other in the treatment of viral infection).
In acute hepatitis B, the drug is prescribed against the background of generally accepted basic therapy.
Interaction with other drugs has not been identified.
The drug is administered s / c.
The standard course of treatment for herpes recurrence includes injections of the drug at a dose of 1 mg every other day, a total of 3 injections per course.
In moderate forms of acute hepatitis B, the drug is administered after verification of the diagnosis at a dose of 1 mg 3 times a week for 3 weeks (9 injections in total).
To prepare a solution for injection, use 1 ml of a 0.9% sodium chloride solution as a solvent.
To date, cases of drug overdose have not been established.
Viruses infect a person, causing diseases such as herpes, hepatitis and papillomas. For their effective treatment, a new generation drug, Allokin-Alpha, was created.
This is an antiviral, immunomodulatory drug based on a natural component obtained by chemical synthesis. The drug is well tolerated and has almost no side effects, it can be safely combined with other medicines.
Allokin-Alpha is used for the following diseases:
Allokin-Alpha is a new generation antiviral agent that has a number of its own features and properties.
The drug is available in the form of a lyophilizate for the manufacture of a solution that is injected subcutaneously. The lyophilized powder is hygroscopic and white in color.
One ampoule of Allokin-Alpha contains 1 mg of alloferon, which is also the main active ingredient. Alloferon is a natural cytokine-like peptide obtained by chemical synthesis. It has a pronounced antitumor and antiviral activity.
Alloferon is an oligopeptide. According to the pharmacological action, it has much in common with alpha interferon. Alloferon is an effective inducer of interferon synthesis and an activator of natural killers.
It stimulates cytotoxic lymphocytes to recognize defective cells and promotes the restoration of T-cell immunity. The experiments revealed a high efficiency of the impact on infections provoked by human papillomaviruses, hepatitis C and B, influenza, herpes types 1 and 2.
Allokin-Alpha is non-toxic, has no carcinogenic and mutagenic effects, allergenic properties, does not affect the reproductive function and toxic effects on the hematopoietic organs.
Excluded hepato-nephrotoxic and embryotoxic effects. The drug has a positive effect on interferon and immune status, is not addictive.
The immunomodulatory and antiviral activity of the drug improves the quality of life of the patient, namely:
The drug is activated only in infected cells and is not introduced into the DNA, it is excreted from the body unchanged.
Allokin-Alpha is available in colorless glass ampoules, each of which contains 1 mg of the drug. Ampoules in the amount of 10, 5, 3, 2 or 1 are placed in a blister pack. One or two blister packs are placed in a small cardboard box along with instructions.
When using the drug for the treatment of human papillomavirus infection, the elimination effect was first obtained in 90% of cases with cervical dysplasia after half a month.
Allokin-Alpha activates natural killers that destroy virus-infected cells and their contents. The drug acts localized, directly in the focus of inflammation, which avoids unnecessary reactions of the immune system.
When using the drug, you should know the dosage and norms, as well as be able to properly inject. This will help not harm your health and quickly recover from the disease.
Before preparing the medicine for injection, you must thoroughly wash your hands with antibacterial soap or treat them with alcohol. Then you should draw 1 ml of a 0.9% sodium chloride solution (physiological saline) into the syringe and inject it directly into the powder ampoule.
The contents must be shaken until a homogeneous liquid is obtained. Then the medicine must be drawn from the ampoule into the syringe. The dosage of the drug per injection is 1 mg.
In order to properly inject, you must perform the following steps:
It is forbidden to reuse the syringe. After the procedure, it must be thrown away.
If you properly dilute Allokin-Alpha, follow all the norms and dosages, as well as the rules for administering the drug intramuscularly, then it can be administered independently.
At the same time, do not forget about cleanliness and thoroughly disinfect your hands, as well as the injection site. Syringes for each injection should be disposable.
If redness, bumps or suppuration are observed at the injection site of the needle, you should immediately consult a doctor. The appearance of various adverse symptoms is also a reason to visit a clinic or hospital.
The drug quickly enters the bloodstream, where it interacts with immune cells. An increase in the level of interferon by 2-2.5 times is noted already two hours after the injection and persists for 6-8 hours. Natural killers are activated after the administration of the drug for seven days.
Allokin-Alpha is a very good and effective medicine, but some features of its use should be taken into account. This will help to avoid complications and possible adverse reactions of the body.
Allokin-Alpha can be used in combination with other drugs. Drug incompatibility is unlikely. In chronic herpes, the medication is prescribed along with antiviral drugs. For the treatment of hepatitis B in the acute stage, Allokin-Alpha is used in combination with basic therapy.
In general, the drug is well tolerated and can be combined with the following dosage forms:
At the time of treatment should stop breastfeeding.
The drug is not prescribed for children from 0-12 years.
For the treatment of infections caused by the human papillomavirus, the drug must be administered every other day. One injection includes 1 mg of the drug. The full course consists of 6 injections.
In case of recurrence of herpes, injections of the drug should be done every other day at a dosage of 1 mg. The course of treatment - 3 injections.
In moderate forms of hepatitis B, the solution is administered three times a week, 1 mg each. Treatment must be continued for three weeks. A total of 9 injections are needed.
Most often in pharmacies you can find Allokin-Alpha in packs of 3 and 6 ampoules. The price of a pack with three ampoules varies from 3450 r. up to 3950 rubles, with six - from 6970 rubles. up to 7500 r.
In the presence of autoimmune diseases, the drug is not recommended. This is due to insufficient knowledge of the effects of the drug on patients in this category.
If during treatment hypersensitivity to the drug is manifested, then its use should be stopped immediately.
In some cases, taking Allokin-alpha may be accompanied by adverse reactions of the body, such as:
The drug can be purchased at a pharmacy, subject to the presentation of a prescription from a doctor.
Allokin-Alpha should be stored in a dark place, protected from light and direct sunlight. Keep away from children. The optimum temperature at which the drug will retain its properties and will not deteriorate is from 2-8 degrees above zero.
The shelf life of the medicine is two years. After this time, the drug should not be used.
There are analogues of Allokin-alpha:
Allokin-Alpha is an effective drug for the treatment of diseases caused by viruses and reduced immunity. He copes with the disease in a short time by activating the natural killer system in the body.
The drug acts localized in the focus of inflammation. The drug should be used, taking into account contraindications. With individual intolerance and the appearance of adverse reactions, the administration of the drug must be discontinued.
INSTRUCTIONS
on the medical use of the drug
Allokin Alpha
(Allokin-Alfa)
pharmachologic effect
Indications for use
Allokin-Alpha is used to treat patients suffering from chronic papillomavirus infection, which is associated with oncogenic types of human papillomavirus. Alloferon can be used as monotherapy for human papillomavirus infection in the absence of clinical and subclinical lesions of the cervix and anogenital area, but if such lesions are present, alloferon is recommended to be used in combination with other drugs.
Allokin-Alpha is prescribed in the complex therapy of chronic recurrent herpes of the second and first types (in this case, therapy should be started as soon as possible after the first symptoms appear).
Alloferon in combination with other drugs is used in the treatment of patients with acute hepatitis B of moderate severity (therapy with Allokin-Alpha should be started no later than the seventh day after the onset of jaundice).
Mode of application
The drug Allokin-Alpha is intended for the preparation of a solution for subcutaneous administration. To prepare the solution, the contents of the ampoule should be dissolved in 1 ml of isotonic sodium chloride solution. It is not recommended to use other drugs as a solvent. Allokin-Alpha must not be mixed with one syringe with other parenteral preparations. Allokin-Alpha solution should be used immediately after preparation. The duration of therapy and the scheme of application of alloferon is determined by the doctor.
In infections caused by oncogenic types of human papillomavirus, as a rule, the administration of 1 mg of alloferon is prescribed every 48 hours.
The total recommended course dose of Allokin-Alpha is 6 injections.
In case of recurrent herpetic infection, as a rule, during an exacerbation, the administration of 1 mg of alloferon is prescribed every 48 hours.
The total recommended course dose of Allokin-Alpha is 3 injections.
Patients with acute hepatitis B of moderate severity, as a rule, after verifying the diagnosis, are prescribed the administration of 1 mg of alloferon three times a week.
The total recommended course dose of Allokin-Alpha is 9 injections.
Depending on the patient's condition and the effectiveness of the therapy, after some time the doctor may prescribe a second course of Allokin-Alpha.
Side effects
Allokin-Alpha, as a rule, is well tolerated by patients. During drug trials, isolated cases of weakness and dizziness were reported.
In addition, patients with herpes infection may develop new elements of the rash.
Contraindications
Allokin-Alpha is not prescribed to patients with individual intolerance to alloferon.
Allokin-Alpha is not used to treat patients suffering from severe autoimmune diseases.
In pediatric practice, the use of alloferon is not recommended.
If patients develop dizziness during alloferon therapy, activities requiring increased concentration should be excluded.
Pregnancy
It is forbidden to use the drug Allokin-Alpha during pregnancy.
During breastfeeding, it is not advisable to use alloferon. If it is impossible to avoid the appointment of Allokin-Alpha during lactation, the issue of interrupting breastfeeding should be resolved.
drug interaction
The combined use of the drug Allokin-Alpha with acyclovir is allowed in the treatment of patients suffering from a chronic recurrent form of genital herpes (due to different mechanisms of action, alloferon and acyclovir mutually potentiate the antiviral effect of each other).
The simultaneous use of alloferon with the basic therapy of hepatitis B is allowed.
Overdose
There are no data on an overdose of Allokin-Alpha.
Release form
Lyophilized powder for the preparation of a solution for subcutaneous use Allokin-Alpha 1 mg in ampoules, in a cardboard box 1, 2, 3, 5 or 10 ampoules placed in a cell package made of polymeric materials.
Storage conditions
Allokin-Alpha should be stored for no more than 2 years after release in rooms with a temperature regime of 2 to 8 degrees Celsius.
Ready solution should not be stored.
Compound
1 ampoule of Allokin-Alpha contains:
Alloferon - 1 mg.