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Glucose is an easily digestible source of valuable nutrition that increases the body's energy reserves and improves its functions.

pharmachologic effect

An isotonic glucose solution 5% is used to replenish fluid in the body. Also, this glucose solution is a source of nutrients, the metabolism of which in the tissues releases a large amount of energy, which is necessary for the full functioning of the body.

There are also hypertonic glucose solutions (10-40%), intravenous administration of which can increase the osmotic pressure of the blood, improve metabolism and antitoxic functions of the liver, and increase the flow of fluid directed from the tissues into the blood.

In addition, the use of a hypertonic glucose solution promotes vasodilation, increased contractility of the heart muscle and an increase in urine volume.

As a general tonic, glucose is used for chronic diseases that are accompanied by physical exhaustion.

The detoxification properties of glucose are due to its ability to activate the liver’s functions to neutralize poisons, as well as a decrease in the concentration of toxins in the blood as a result of an increase in the volume of circulating fluid and increased urination.

Indications for use of Glucose solution

Glucose solution is prescribed for:

• hypoglycemia (low blood glucose levels);
• carbohydrate deficiency;
• intoxications accompanying liver diseases (liver failure, hepatitis);
• toxic infections (poisoning caused by microbes entering the body with food);
• hemorrhagic diathesis (a disease of the blood system manifested in the form of increased bleeding);
• dehydration caused by diarrhea, vomiting or in the postoperative period;
• intoxications;
• collapse (sharp drop in blood pressure);
• shocked.

Glucose can be used to prepare solutions of drugs for intravenous administration, as well as as a component of anti-shock and blood-substituting fluids.

Mode of application

Glucose 5% can be introduced into the body in any way (intravenously, subcutaneously, into the rectum), since its osmotic pressure corresponds to the osmotic pressure of the blood. Hypertonic glucose solutions are administered only intravenously, since their osmotic pressure significantly exceeds that in tissues and blood.

It is recommended to increase glucose levels by oral administration (tablets) using 0.5-1 g of the drug per dose. The use of a 5% glucose solution using an enema involves the drip administration of 200 ml, 500 ml or 1000 ml of the drug at a time, while the daily dose should not exceed 2000 ml.

A 5% glucose solution can be administered intravenously (drip) or subcutaneously in a volume.

Hypertonic glucose solution can be prescribed as a single injection or drip injection (daily dose).

Side effects

The use of recommended doses of glucose, as a rule, does not cause undesirable effects. In rare cases, the drug can provoke fever, hyperglycemia (increased blood glucose levels), acute left ventricular failure, hypervolemia (increased circulating blood volume), increased urine production. Local reactions of the body to the use of glucose can manifest themselves in the form of thrombophlebitis, bruising, infection, and local pain.

When using glucose 5% as a solvent for other drugs, side effects are caused by the action of these drugs.

Contraindications

Drug-induced increases in glucose levels can be dangerous if:

• decompensated diabetes mellitus (always high blood sugar);
• decreased glucose tolerance;
• hyperglycemia;
• hyperosmolar coma (a special type of diabetic coma);
• hyperlactic acidemia (increased levels of lactic acid in the blood in diabetes mellitus).

Caution is necessary when administering glucose solution to patients with chronic renal failure, hyponatremia and decompensated chronic heart failure.

The use of glucose during pregnancy and breastfeeding is permitted. It should be remembered that in women bearing children, the level of glucose in the urine rises, which is due to hyperglycemia and relatively insufficient insulin production. In order to prevent the development of diabetes mellitus, it is necessary to closely monitor glucose fluctuations during pregnancy.

Additional Information

Glucose should be stored at air temperatures from 15 0 C to 25 0 C. The shelf life of the drug depends on the form of release - from 2 to 10 years.

Glucose tab. 500mg n10

Glucose tablets 0.5 g 10 pcs.

Glucose 500 mg No. 20 tablets

Glucose solution for infusion 5% 200 ml bottle

Glucose solution 5% 250 ml

Glucose solution for infusion 10% 200 ml bottle

Glucose solution 5% 100 ml

Information about the drug is generalized, provided for informational purposes and does not replace official instructions. Self-medication is dangerous to health!

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Why do they drip glucose?

Why do they drip glucose?

Glucose is absorbed very well and quickly by the body, and also saturates it with energy. It is used to quickly restore strength. It is used for many ailments. Such as: under stress, lack of sugar, low blood pressure, poor liver and heart function.

Glucose is a very easily digestible source of nutrition for the human body, which can increase both energy reserves and improve the body's performance functions.

Glucose droppers are used for detoxification, that is, removing toxins from the human body and replenishing fluid lost in it.

As a general maintenance therapy, glucose is used if a person experiences general physical exhaustion.

Glucose solution can be prescribed for:

intoxications and poisonings

for hepatitis and liver diseases

for diseases of the blood system

for severe diarrhea

and other problems.

Glucose is a substance that quickly replenishes nutritional deficiencies in the human body in order to improve tone and increase energy.

Once I was put on a glucose drip for poisoning, because I felt simply terrible and had a huge loss of strength. I agree with one answer that glucose is not prescribed to detoxify the body. The most important task of glucose is to provide nutrition to the body as quickly as possible.

Also, as far as I know, glucose is very useful for low blood pressure.

Glucose is the most versatile source of energy, as it is easily absorbed and is subject to rapid breakdown in the body.

1) For various types of intoxication and poisoning;

2) When blood pressure drops in order to improve blood pressure;

3) In case of cardiac dysfunction;

4) In case of dysfunction of a=liver;

5) To increase sugar levels if they have dropped significantly;

6) After severe stressful situations;

7) When the body is depleted in order to normalize metabolism.

Most often, glucose is dropped to remove signs of intoxication, that is, to destroy toxins in the body or to wash away unwanted drugs. A very effective and fast-acting method. They are also dripped after operations to speed up the healing of soft tissues.

Several times I was faced with the need to inject glucose into my animals. The point is that it is a good power source. If for some reason, for example, animals cannot eat, in order to maintain their health they do not drip, in this way they essentially do not feed.

Glucose droppers are given to a person for certain diseases.

Glucose is administered intravenously for hypoglycemia, when blood sugar levels are low. It is necessary for those who have infectious diseases.

Glucose is administered when there is a sharp decrease in the pumping function of the heart (decompensation of cardiac activity).

Glucose is necessary for liver diseases, pulmonary edema, hemorrhagic diathesis (increased bleeding), shock and a sharp drop in blood pressure (collapse).

Glucose solution is used mainly to replenish fluid in the body. Droppers are prescribed for

low blood glucose levels

a sharp decrease in blood pressure

in the postoperative period

poisoning caused by microbes that entered the body with food

Glucose droppers have been used in medicine for a long time.

Glucose is a source of energy that is easily absorbed. Studies have also been conducted that have proven that glucose relieves stress.

A glucose drip is given in the following cases:

firstly, to improve blood pressure, with a sharp drop in blood pressure,

secondly, to improve liver function, after a drip it works better,

thirdly, to improve metabolism in the human body, as well as when the body is exhausted,

fourthly, to improve the functioning of the heart muscle,

fifthly, if your blood sugar level has dropped significantly,

sixthly, if a person is in a state of shock,

seventhly, in case of alcohol poisoning.

• how to inject glucose

• - 1 ml syringe;
• - medicine;
• - cotton ball or disk;
• - alcohol.

Isotonic glucose solutions are administered subcutaneously, intravenously or rectally, in the form of enemas. If the drug is used subcutaneously, glucose is infused in a stream, poured or more in one injection. For rectal administration - by drip, 200, 500 and 1000 ml. The maximum amount consumed is 2 liters per day.

When administered intravenously by drip, the solution is delivered at a rate of up to 7 ml per minute (or 400 ml/hour), in a volume of 300 - 500 ml. The daily dose for adults should also not exceed two liters.

Hypertonic solutions are administered intravenously in a stream, 10–100 ml per injection. It is possible to use the product in the form of droppers. The rate of administration of a 10% solution can reach up to 60 drops (3 ml) per minute. The permissible daily dose is ml.

Why do they drip glucose?

Glucose is a universal source of energy, as it is immediately broken down in the body and is very easily absorbed. What they write that they say is for detoxification or fluid replenishment is bullshit, since the glucose solution almost immediately leaves the bloodstream (5-10 minutes after entering the bloodstream) into the tissues where it is already metabolized, providing cells with the necessary energy, in addition it draws water onto itself, so there is no way to flood it. For detoxification, more crystalloids and less colloids are used (for example, regular saline solution, rheosorbilact, sorbilact, rheopolyglucin, ringer, etc.). Use a 5% glucose solution.

A 40% solution is also used, which is administered intravenously in a stream in case of hypoglycemic coma (as a rule, with an overdose of insulin), the patient is literally at the end of a needle, as soon as you begin to inject it, he comes to his senses. It is also an excellent remedy for relieving acetone syndrome in children. As soon as you smell acetone from your mouth, let the child drink 10 ml of 40% glucose, if everything is done on time, vomiting, etc. can be avoided.

Glucose dropper: what is it for and how it helps the body

In case of poisoning, glucose included in the droppers is the most important source of energy for maintaining life processes in the cells of the human body.

Glucose (dextrose, grape sugar) is a universal “fuel” for the body, an essential substance that ensures the functioning of brain cells and the entire nervous system of the human body.

A dropper with prepared glucose is used in modern medicine as a means of providing energy support, allowing the patient’s condition to be normalized in the shortest possible time in case of serious illnesses, injuries, or after surgical interventions.

Properties of glucose

The substance was first isolated and described by the British physician W. Prout at the beginning of the 19th century. It is a sweet-tasting compound (carbohydrate), the molecule of which is made up of 6 carbon atoms.

It is formed in plants through photosynthesis and is found in its pure form only in grape berries. The human body normally enters through food containing starch and sucrose and is released during digestion.

The body forms a “strategic reserve” of this substance in the form of glycogen, using it as an additional source of energy to maintain life in the event of emotional, physical or mental overload, illness or other extreme situations.

For the human body to function normally, blood glucose levels should be approximately 3.5-5 mmol per liter. Several hormones regulate the amount of the substance, the most important being insulin and glucagon.

Glucose is constantly used as a source of energy for neurons, muscle and blood cells.

• ensuring metabolism in cells;
• normal course of redox processes;
• normalization of liver function;
• replenishing energy reserves;
• maintaining fluid balance;
• enhancing the elimination of toxins.

The use of glucose intravenously for medical purposes helps restore the body after poisoning, illness, and surgery.

Effect on the body

The rate of dextrose is individual and is dictated by both the characteristics and type of human activity.

The highest daily need for it is among people who engage in intense mental or heavy physical labor (due to the need for additional sources of energy).

The body suffers equally from a lack and excess of sugar in the blood:

• excess provokes intensive work of the pancreas to produce insulin and bring glucose levels back to normal, which causes premature wear of the organ, inflammation, degeneration of liver cells into fat cells, and disrupts the functioning of the heart;
• deficiency causes starvation of brain cells, exhaustion and weakening, causing general weakness, anxiety, confusion, fainting, and neuronal death.

The main causes of lack of glucose in the blood are:

• incorrect human nutrition, insufficient amount of food that enters the gastrointestinal tract;
• food and alcohol poisoning;
• disturbances in the functioning of the body (thyroid disease, aggressive neoplasms, disturbances in the gastrointestinal tract, infections of various kinds).

The required level of this substance in the blood must be maintained to ensure vital functions - normal functioning of the heart, central nervous system, muscles, optimal body temperature.

Normally, the required level of the substance is replenished with nutrition; in the case of a pathological condition (trauma, illness, poisoning), glucose is prescribed to stabilize the condition.

Conditions for which dextrose is used

For medical purposes, a dextrose dropper is used for:

• lowering blood sugar levels;
• physical and intellectual exhaustion;
• long-term course of a number of diseases (infectious hepatitis, gastrointestinal infections, viral lesions with intoxication of the central nervous system) as an additional source of energy replenishment for the body;
• disturbances in the functioning of the heart;
• shock states;
• a sharp decrease in blood pressure, including after blood loss;
• acute dehydration due to intoxication or infection, including medications, alcohol and drugs (accompanied by diarrhea and profuse vomiting);
• pregnancy to support fetal development.

The main dosage forms used in medicine are solutions and tablets.

Dosage forms

Solutions are the most optimal; their use helps to quickly support and normalize the functioning of the patient’s body.

In medicine, two types of Dextrose solutions are used, which differ in the scheme of application:

• isotonic 5%, used to improve the functioning of organs, their parenteral nutrition, maintain water balance, allows you to provide additional energy for life;
• hypertonic, normalizing metabolism and liver function, osmotic blood pressure, enhancing cleansing of toxins, has different concentrations (up to 40%).

Most often, glucose is administered intravenously, as an injection of a high-concentration hypertonic solution. Drip administration is used if a constant flow of medication into the vessels is required over a period of time.

After entering the body intravenously, dextrose breaks down into carbon dioxide and water under the action of acids, releasing the energy needed by the cells.

Glucose in isotonic solution

Dextrose 5% concentration is delivered to the patient’s body in all possible ways, as it corresponds to the osmotic parameters of the blood.

Most often it is administered by drip using a system of 500 ml. up to 2000 ml. per day. For ease of use, glucose (drip solution) is packaged in transparent polyethylene bags with a volume of 400 ml or glass bottles of the same capacity.

An isotonic solution is used as a basis for diluting other drugs necessary for treatment, and the effect of such a dropper on the body will be determined by the combined effect of glucose and a specific medicinal substance in its composition (cardiac glycosides or other drugs for fluid loss, ascorbic acid).

In some cases, side effects are possible with drip administration:

• violation of liquid-salt metabolism;
• weight change due to fluid accumulation;
• excessive appetite;
• increased body temperature;
• blood clots and hematomas at the injection sites;
• increased blood volume;
• excess blood sugar levels (in severe cases, coma).

This may be caused by incorrect determination of the amount of fluid lost by the body and the volume of the dropper needed to replenish it. Regulation of excessively administered fluid is carried out with diuretics.

Hypertonic dextrose solution

The main route of administration of the solution is intravenously. For droppers, the drug is used in the concentration prescribed by the doctor (10-40%) at a rate of no more than 300 ml per day in case of a sharp decrease in blood sugar levels, large blood losses after injuries and bleeding.

Drip administration of concentrated glucose allows you to:

• optimize liver function;
• improve heart function;
• restore the correct fluid balance of the body;
• enhances the removal of fluid from the body;
• improves tissue metabolism;
• dilates blood vessels.

The rate of infusion of the substance per hour, the volume to be administered intravenously per day, is determined by the age and weight of the patient.

• adults – no more than 400 ml;
• children – up to 170 ml. per 1000 grams of weight, infants - 60 ml.

In case of hypoglycemic coma, a glucose drip is placed as a means of resuscitation, for which, according to the doctor’s instructions, the patient’s blood sugar level is constantly monitored (as the body’s response to treatment).

Features of the use of droppers

A disposable plastic system is used to transport the medicinal solution into the patient’s blood. The appointment of a dropper is carried out when it is necessary that the medicine enters the blood slowly, and the amount of the drug does not exceed the desired level.

Why is this necessary?

If the amount of the drug is too large, adverse reactions, including allergies, may occur; if the concentration is low, the medicinal effect will not be achieved.

Most often, glucose (dropper) is prescribed for severe diseases, the treatment of which requires the constant presence of the active substance in the blood in the required concentration. Medicines introduced into the body by drip act quickly, and the doctor can monitor the effect of the treatment.

They are dripped intravenously if it is necessary to introduce a large amount of medicine or liquid into the vessels to stabilize the patient’s condition after poisoning, in case of impaired kidney or heart function, or after surgical interventions.

The system is not installed in cases of acute heart failure, kidney disorders and a tendency to edema, venous inflammation (the decision is made by the doctor, studying each specific case).

Glucose dropper: what is it prescribed for? Indications and contraindications for the use of the drug

Glucose is the main source of energy in cellular metabolism, as well as a supplier of carbohydrates in parenteral nutrition with easy digestibility. It helps to increase the energy potential of the body and stimulates its basic functions. So, glucose drip: what is it used for?

When is glucose solution for infusion prescribed?

As a rule, for infusion, that is, intravenous administration using a dropper, a 5% glucose solution is used, packaged in sealed plastic bags with a volume of 400 ml or bottles. The solution consists of the active substance, glucose and water for injection.

When administered intravenously, glucose is metabolized by acids, breaking down into carbon dioxide and water, releasing energy. Subsequent pharmacodynamics are determined by the nature of the drug used, which is diluted with glucose.

A glucose dropper is indicated for the treatment of diseases such as:

• state of shock;
• bleeding;
• increased bleeding;
• diarrhea and vomiting;
• a critical decrease in plasma sugar levels during hypoglycemia;
• acute heart failure;
• a sharp drop in blood pressure, characteristic of a state of collapse;
• accumulation of fluid in the lungs;
• liver disease;
• infectious diseases;
• dehydration and carbohydrate depletion, when normal food and fluid intake is limited;
• as a carrier and diluent for other compatible medications.

Contraindications and precautions

Infusions with glucose solution are contraindicated for people with the following pathologies:

• decompensated diabetes mellitus;
• glucose intolerance, for example, in the case of metabolism in stressful situations;
• with hyperosmolar coma;
• in case of hyperglycemia and hyperlactaemia.

Cautions for use:

• Large volumes of infusion of the solution must be carried out under special supervision in patients with water intoxication, heart failure, the presence of fluid in the lungs or kidney edema.
• Due to the risk of hyperglycemia, the solution should be administered with caution to patients who have suffered an ischemic stroke.
• For traumatic brain injuries, the infusion solution should be used during the first 24 hours, carefully monitoring the plasma glucose concentration.
• Glucose should not be infused simultaneously, after and immediately before blood transfusion into the same vein, which can provoke hemolysis and nonspecific agglutination.
• Intravenous administration of glucose solutions to infants, especially premature or low-weight infants, requires careful control over the duration of treatment, since this category of patients has a significant risk of hyper- or hypoglycemia.

Dosage

The duration of administration of intravenous glucose solution and its dosage are prescribed taking into account several factors, such as the patient's age, weight, general condition and clinical picture. This may require careful monitoring of blood glucose levels.

To treat dehydration and carbohydrate depletion, the following dosage is recommended:

• For adults: 0.5 - 3 l/24 hours.
• For children, including newborns, the dosage is calculated per kilogram of the child’s weight:

• body weight up to 10 kgml per kilogram of weight during the day;
• weight from 10 to 20 kg - 1 l/kg/24 h;
• more than 20 kg - 1.5 l/kg/24 hours.

To avoid the development of hyperglycemia, the rate of solution administration is adjusted depending on the clinical picture. Maximum infusion rate:

• for adults - from 5 mg per kilogram of body weight per minute;
• for children, including infants mg/kg/min.

If glucose is used for transport and dilution, the recommended dosage is within ml for one dose of the drug.

How is it used?

Glucose is administered intravenously using a dropper. When using a solution for the purpose of diluting and administering additional therapeutic agents, the infusion is carried out according to the instructions for use of these drugs. Infusion requires sterile equipment that must be sealed to prevent air from entering the system.

Plastic bags should not be used for a series connection, which carries the risk of sucking in residual air in the first before the solution coming from the next is complete, since an air embolism may result. Pressing on flexible plastic IV bags to increase the rate of infusion can also cause an air embolism if residual air is not completely removed from the container before administering the solution.

Additional medications may be added to the solution either before or during the infusion. The solution containing the medicinal additive must be used immediately as it cannot be stored.

Why is glucose given intravenously?

Glucose is a powerful source of nutrition that is easily absorbed by the body. This solution is very valuable for the human body, since the healing liquid has the power to significantly improve energy reserves and restore weakened performance functions. The most important task of glucose is to provide and give the body the necessary source of complete nutrition.

Glucose solutions have long been effectively used in medicine for injection therapy. But why do they drip glucose intravenously, in what cases do doctors prescribe such treatment, and is it suitable for everyone? This is worth talking about in more detail.

What is glucose

Glucose (or dextrose) is actively involved in a variety of metabolic processes in the human body. This medicinal substance has diverse effects on the systems and organs of the body. Dextrose:

1. Improves cellular metabolism.
2. Reanimates weakened liver functions.
3. Replenishes lost energy reserves.
4. Stimulates the basic functions of internal organs.
5. Helps with detoxification therapy.
6. Strengthens redox processes.
7. Replenishes significant loss of fluid in the body.

When a glucose solution penetrates the body, its active phosphorylation begins in the tissues. That is, dextrose is converted into glucose-6-phosphate.

Glucose-6-phosphate or phosphorylated glucose is an important participant in the main metabolic processes occurring in the human body.

Forms of release of the drug

Dextrose is produced by the pharmaceutical industry in two forms. Both forms of solution are useful for people with weakened bodies, but have their own nuances in use.

Isotonic solution

This type of dextrose is intended to restore the functioning of weakened internal organs, as well as to replenish lost fluid reserves. This 5% solution is a powerful source of nutrients essential for human life.

An isotonic solution is administered in different ways:

1. Subcutaneously. The daily volume of administered medication in this case is 300-500 ml.
2. Intravenously. Doctors may prescribe the medication intravenously (300-400 ml per day).
3. Enema. In this case, the total amount of administered solution is about 1.5-2 liters per day.

It is not recommended to administer glucose intramuscularly in its pure form. In this case, there is a high risk of developing purulent inflammation of the subcutaneous tissue. Intravenous injections are prescribed if a slow and gradual infusion of dextrose is not required.

Hypertonic solution

This type of dextrose is necessary to improve the functioning of a damaged liver and resuscitate metabolic processes. Additionally, a hypertonic solution restores normal diuresis and promotes vasodilation. Also this dropper with glucose (10-40% solution):

• increases metabolic processes;
• improves myocardial functioning;
• increases the volume of urine produced;
• promotes dilation of blood vessels;
• increases the antitoxic functions of the liver organ;
• enhances the passage of fluid and tissue into the bloodstream;
• increases the osmotic pressure of the blood (this pressure ensures normal water exchange between body tissues).

Hypertonic solution is prescribed by doctors in the form of injections and droppers. When it comes to injections, dextrose is most often administered intravenously. It can also be used in combination with other medications. Many people, especially athletes, prefer to drink glucose.

The hypertonic solution, administered by injection, is diluted with thiamine, ascorbic acid or insulin. A single dose in this case is about 25-50 ml.

The medicinal power of droppers

For infusion (intravenous), a 5% dextrose solution is usually used. The healing liquid is packaged in plastic, hermetically sealed bags or 400 ml bottles. The infusion solution consists of:

1. Purified water.
2. Directly glucose.
3. Active excipient.

When dextrose enters the bloodstream, it breaks down into water and carbon dioxide, actively producing energy. The subsequent pharmacology depends on the nature of the additional drugs used that are part of the droppers.

Why do they put in a glucose drip?

The purpose of such therapeutic treatment is carried out for many different diseases and further rehabilitation of an organism weakened by pathology. A glucose dropper is especially beneficial for health, for which it is prescribed in the following cases:

• hepatitis;
• pulmonary edema;
• dehydration;
• diabetes;
• liver pathologies;
• state of shock;
• hemorrhagic diathesis;
• internal bleeding;
• alcohol intoxication;
• general exhaustion of the body;
• a sharp decrease in blood pressure (collapse);
• profuse, persistent vomiting;
• infectious diseases;
• relapse of heart failure;
• accumulation of fluid in the pulmonary organs;
• stomach upset (prolonged diarrhea);
• exacerbation of hypoglycemia, in which there is a drop in blood sugar to a critical level.

Also, intravenous infusion of dextrose is indicated if it is necessary to introduce certain medications into the body. In particular, cardiac glycosides.

Side effects

Isotonic dextrose solution in rare cases can cause a number of side effects. Namely:

• increased appetite;
• weight gain;
• feverish conditions;
• necrosis of subcutaneous tissue;
• blood clots at the IV site;
• hypervolemia (increased blood volume);
• overhydration (violation of water-salt metabolism).

If the solution is prepared incorrectly and dextrose is introduced into the body in increased quantities, more tragic consequences can occur. In this case, an attack of hyperglycemia and, in especially severe cases, a coma may occur. Shock occurs due to a sharp increase in sugar in the patient's blood.

So, while useful, intravenous glucose should only be used when indicated. And directly as prescribed by a doctor, and procedures should only be carried out under medical supervision.

Glucose solution: instructions for use for intravenous infusion

Glucose is one of the main enemies of a diabetic. Its molecules, despite their relatively large sizes in relation to salt molecules, are capable of leaving the vascular bed quite quickly.

Therefore, dextrose moves from the intercellular space into the cells. This process becomes the main reason for additional insulin production.

This release results in metabolism to water and carbon dioxide. If there is an excessive concentration of dextrose in the bloodstream, then the excess drug is eliminated without obstacles through the kidneys.

Composition and features of the solution

The drug contains for every 100 ml:

1. glucose 5 g or 10 g (active substance);
2. sodium chloride, water for injection 100 ml, hydrochloric acid 0.1 M (excipients).

Glucose solution is a colorless or slightly yellowish liquid.

Glucose is an important monosaccharide that covers part of the energy expenditure. It is the main source of easily digestible carbohydrates. The calorie content of the substance is 4 kcal per gram.

The composition of the drug is capable of having a diverse effect: enhancing oxidative and reduction processes, improving the antitoxic functioning of the liver. After intravenous administration, the substance significantly reduces nitrogen and protein deficiency, and also accelerates the accumulation of glycogen.

An isotonic drug 5% is partially capable of replenishing water deficiency. It has a detoxifying and metabolic effect, being a supplier of valuable and quickly absorbed nutrients.

When administering 10% hypertonic glucose solution:

• the osmotic pressure of the blood increases;
• the flow of fluid into the bloodstream increases;
• metabolic processes are stimulated;
• the cleaning function is qualitatively improved;
• diuresis increases.

Who is the drug indicated for?

A 5% solution administered intravenously promotes:

• rapid replenishment of lost fluid (with general, extracellular and cellular dehydration);
• elimination of shock conditions and collapse (as one of the components of anti-shock and blood replacement fluids).

The 10% solution has the following indications for use and intravenous administration:

1. with dehydration (vomiting, indigestion, in the postoperative period);
2. in case of poisoning with all kinds of poisons or drugs (arsenic, narcotic drugs, carbon monoxide, phosgene, cyanide, aniline);
3. for hypoglycemia, hepatitis, dystrophy, liver atrophy, edema of the brain and lungs, hemorrhagic diathesis, septic heart problems, infectious diseases, toxic infections;
4. during the preparation of drug solutions for intravenous administration (concentration 5% and 10%).

How should the drug be used?

An isotonic solution of 5% should be dripped at the maximum possible speed of 7 ml per minute (150 drops per minute or 400 ml per hour).

For adults, the drug can be used intravenously in a volume of 2 liters per day. It is possible to take the drug subcutaneously and in enemas.

Hypertonic solution (10%) is indicated for use only by intravenous administration in a volume of 20/40/50 ml per infusion. If there are indications, then drip it no faster than 60 drops per minute. The maximum dose for adults is 1000 ml.

The exact dose of the drug administered intravenously will depend on the individual needs of each individual organism. Adults without excess weight can take no more than 4-6 g/kg per day (approximately 24 hours). In this case, the amount of fluid administered should be 30 ml/kg per day.

With a reduced intensity of metabolic processes, there are indications to reduce the daily dose of dog.

If long-term therapy is required, this should be done under careful monitoring of serum sugar levels.

For rapid and complete absorption of glucose, in some cases, simultaneous administration of insulin is required.

The likelihood of adverse reactions to the substance

The instructions for use state that the composition or main substance in some cases can cause negative reactions of the body to the introduction of glucose 10%, for example:

• fever;
• hypervolemia;
• hyperglycemia;
• acute failure in the left ventricle.

Long-term use (or too rapid administration of large volumes) of the drug can cause swelling, water intoxication, impaired functional state of the liver, or depletion of the insular apparatus of the pancreas.

In those places where the intravenous system was connected, infections, thrombophlebitis and tissue necrosis may develop if there is hemorrhage. Such reactions to the glucose drug in ampoules can be caused by decomposition products or due to incorrect administration tactics.

With intravenous administration, disturbances in electrolyte metabolism may be noted:

In order to avoid adverse reactions to the composition of the drug in patients, it is necessary to carefully follow the recommended dosage and correct administration technique.

Who is contraindicated for glucose?

Instructions for use provide information about the main contraindications:

• diabetes;
• swelling of the brain and lungs;
• hyperglycemia;
• hyperosmolar coma;
• hyperlactic acidemia;
• circulatory disruptions that threaten the development of pulmonary and cerebral edema.

Interaction with other drugs

Glucose solution 5% and 10% and its composition promotes easier absorption of sodium from the digestive tract. The drug can be recommended in combination with ascorbic acid.

Simultaneous intravenous administration should be at the rate of 1 unit per 4-5 g, which promotes maximum absorption of the active substance.

In view of this, glucose 10% is a fairly strong oxidizing agent that cannot be administered simultaneously with hexamethylenetetramine.

It is better not to take glucose with:

• solutions of alkaloids;
• general anesthetics;
• sleeping pills.

The solution is able to weaken the effects of analgesics, adrenomimetic drugs and reduce the effectiveness of nystatin.

Some introduction nuances

When using the drug intravenously, you should always keep your blood sugar levels under control. The administration of large volumes of glucose can be fraught for those diabetics who have significant electrolyte loss. A 10% solution cannot be used after acute attacks of ischemia due to the negative impact of hyperglycemia on the treatment process.

If there are indications, the drug can be used in pediatrics, pregnancy and lactation.

The description of the substance suggests that glucose is not able to influence the ability to control mechanisms and transport.

Cases of overdose

If there has been excessive consumption, the drug will cause severe symptoms of side effects. The development of hyperglycemia and coma is very likely.

If the sugar concentration increases, shock may occur. In the pathogenesis of these conditions, the osmotic movement of fluid and electrolytes plays an important role.

The solution for infusion can be produced in 5% or 10% concentration in containers of 100, 250, 400 and 500 ml.

Glucose is one of the main enemies of a diabetic. Its molecules, despite their relatively large sizes in relation to salt molecules, are capable of leaving the vascular bed quite quickly.

Therefore, dextrose moves from the intercellular space into the cells. This process becomes the main reason for additional insulin production.

This release results in metabolism to water and carbon dioxide. If there is an excessive concentration of dextrose in the bloodstream, then the excess drug is eliminated without obstacles through the kidneys.

Composition and features of the solution

The drug contains for every 100 ml:

1. glucose 5 g or 10 g (active substance);
2. sodium chloride, water for injection 100 ml, hydrochloric acid 0.1 M (excipients).

Glucose solution is a colorless or slightly yellowish liquid.

Glucose is an important monosaccharide that covers part of the energy expenditure. It is the main source of easily digestible carbohydrates. The calorie content of the substance is 4 kcal per gram.

The composition of the drug is capable of having a diverse effect: enhancing oxidative and reduction processes, improving the antitoxic functioning of the liver. After intravenous administration, the substance significantly reduces nitrogen and protein deficiency, and also accelerates the accumulation of glycogen.

An isotonic drug 5% is partially capable of replenishing water deficiency. It has a detoxifying and metabolic effect, being a supplier of valuable and quickly absorbed nutrients.

When administering 10% hypertonic glucose solution:

• the osmotic pressure of the blood increases;
• the flow of fluid into the bloodstream increases;
• metabolic processes are stimulated;
• the cleaning function is qualitatively improved;
• diuresis increases.

Who is the drug indicated for?

A 5% solution administered intravenously promotes:

• rapid replenishment of lost fluid (with general, extracellular and cellular dehydration);
• elimination of shock conditions and collapse (as one of the components of anti-shock and blood replacement fluids).

The 10% solution has the following indications for use and intravenous administration:

1. with dehydration (vomiting, indigestion, in the postoperative period);
2. in case of poisoning with all kinds of poisons or drugs (arsenic, narcotic drugs, carbon monoxide, phosgene, cyanide, aniline);
3. for hypoglycemia, hepatitis, dystrophy, liver atrophy, edema of the brain and lungs, hemorrhagic diathesis, septic heart problems, infectious diseases, toxic infections;
4. during the preparation of drug solutions for intravenous administration (concentration 5% and 10%).

How should the drug be used?

An isotonic solution of 5% should be dripped at the maximum possible speed of 7 ml per minute (150 drops per minute or 400 ml per hour).

For adults, the drug can be used intravenously in a volume of 2 liters per day. It is possible to take the drug subcutaneously and in enemas.

Hypertonic solution (10%) is indicated for use only by intravenous administration in a volume of 20/40/50 ml per infusion. If there are indications, then drip it no faster than 60 drops per minute. The maximum dose for adults is 1000 ml.

The exact dose of the drug administered intravenously will depend on the individual needs of each individual organism. Adults without excess weight can take no more than 4-6 g/kg per day (approximately 250-450 g per day). In this case, the amount of fluid administered should be 30 ml/kg per day.

With a reduced intensity of metabolic processes, there are indications to reduce the daily dose to 200-300 g.

If long-term therapy is required, this should be done under careful monitoring of serum sugar levels.

For rapid and complete absorption of glucose, in some cases, simultaneous administration of insulin is required.

The likelihood of adverse reactions to the substance

The instructions for use state that the composition or main substance in some cases can cause negative reactions of the body to the introduction of glucose 10%, for example:

• fever;
• hypervolemia;
• hyperglycemia;
• acute failure in the left ventricle.

Long-term use (or too rapid administration of large volumes) of the drug can cause swelling, water intoxication, impaired functional state of the liver, or depletion of the insular apparatus of the pancreas.

In those places where the intravenous system was connected, infections, thrombophlebitis and tissue necrosis may develop if there is hemorrhage. Such reactions to the glucose drug in ampoules can be caused by decomposition products or due to incorrect administration tactics.

With intravenous administration, disturbances in electrolyte metabolism may be noted:

• hypophosphatemia;
• hypomagnesemia.

In order to avoid adverse reactions to the composition of the drug in patients, it is necessary to carefully follow the recommended dosage and correct administration technique.

Who is contraindicated for glucose?

Instructions for use provide information about the main contraindications:

• diabetes;
• swelling of the brain and lungs;
• hyperglycemia;
• hyperosmolar coma;
• hyperlactic acidemia;
• circulatory disruptions that threaten the development of pulmonary and cerebral edema.

Interaction with other drugs

Glucose solution 5% and 10% and its composition promotes easier absorption of sodium from the digestive tract. The drug can be recommended in combination with ascorbic acid.

Simultaneous intravenous administration should be at the rate of 1 unit per 4-5 g, which promotes maximum absorption of the active substance.

In view of this, glucose 10% is a fairly strong oxidizing agent that cannot be administered simultaneously with hexamethylenetetramine.

It is better not to take glucose with:

• solutions of alkaloids;
• general anesthetics;
• sleeping pills.

The solution is able to weaken the effects of analgesics, adrenomimetic drugs and reduce the effectiveness of nystatin.

Some introduction nuances

When using the drug intravenously, you should always keep your blood sugar levels under control. The administration of large volumes of glucose can be fraught for those diabetics who have significant electrolyte loss. A 10% solution cannot be used after acute attacks of ischemia due to the negative impact of hyperglycemia on the treatment process.

If there are indications, the drug can be used in pediatrics, pregnancy and lactation.

The description of the substance suggests that glucose is not able to influence the ability to control mechanisms and transport.

Cases of overdose

If there has been excessive consumption, the drug will cause severe symptoms of side effects. The development of hyperglycemia and coma is very likely.

If the sugar concentration increases, shock may occur. In the pathogenesis of these conditions, the osmotic movement of fluid and electrolytes plays an important role.

The solution for infusion can be produced in 5% or 10% concentration in containers of 100, 250, 400 and 500 ml.

Instructions for use:

Prices in online pharmacies:

Glucose is an easily digestible source of valuable nutrition that increases the body's energy reserves and improves its functions.

pharmachologic effect

Glucose is used as a means for detoxification (removing toxins from the body) and rehydration (replenishing fluid losses).

An isotonic glucose solution 5% is used to replenish fluid in the body. Also, this glucose solution is a source of nutrients, the metabolism of which in the tissues releases a large amount of energy, which is necessary for the full functioning of the body.

There are also hypertonic glucose solutions (10-40%), intravenous administration of which can increase the osmotic pressure of the blood, improve metabolism and antitoxic functions of the liver, and increase the flow of fluid directed from the tissues into the blood.

In addition, the use of a hypertonic glucose solution promotes vasodilation, increased contractility of the heart muscle and an increase in urine volume.

As a general tonic, glucose is used for chronic diseases that are accompanied by physical exhaustion.

The detoxification properties of glucose are due to its ability to activate the liver’s functions to neutralize poisons, as well as a decrease in the concentration of toxins in the blood as a result of an increase in the volume of circulating fluid and increased urination.

Indications for use of Glucose solution

Glucose solution is prescribed for:

• hypoglycemia (low blood glucose levels);
• carbohydrate deficiency;
• intoxications accompanying liver diseases (liver failure, hepatitis);
• toxic infections (poisoning caused by microbes entering the body with food);
• hemorrhagic diathesis (a disease of the blood system manifested in the form of increased bleeding);
• dehydration caused by diarrhea, vomiting or in the postoperative period;
• intoxications;
• collapse (sharp drop in blood pressure);
• shocked.

Glucose can be used to prepare solutions of drugs for intravenous administration, as well as as a component of anti-shock and blood-substituting fluids.

Glucose 5% can be introduced into the body in any way (intravenously, subcutaneously, into the rectum), since its osmotic pressure corresponds to the osmotic pressure of the blood. Hypertonic glucose solutions are administered only intravenously, since their osmotic pressure significantly exceeds that in tissues and blood.

It is recommended to increase glucose levels by oral administration (tablets) using 0.5-1 g of the drug per dose. The use of a 5% glucose solution using an enema involves the drip administration of 200 ml, 500 ml or 1000 ml of the drug at a time, while the daily dose should not exceed 2000 ml.

A 5% glucose solution can be administered intravenously (drip) or subcutaneously in a volume of 300-500 ml.

Hypertonic glucose solution can be prescribed as a single injection of 10-100 ml or drip injection of 200-300 ml (daily dose).

The use of recommended doses of glucose, as a rule, does not cause undesirable effects. In rare cases, the drug can provoke fever, hyperglycemia (increased blood glucose levels), acute left ventricular failure, hypervolemia (increased circulating blood volume), increased urine production. Local reactions of the body to the use of glucose can manifest themselves in the form of thrombophlebitis, bruising, infection, and local pain.

When using glucose 5% as a solvent for other drugs, side effects are caused by the action of these drugs.

Drug-induced increases in glucose levels can be dangerous if:

• decompensated diabetes mellitus (always high blood sugar);
• decreased glucose tolerance;
• hyperglycemia;
• hyperosmolar coma (a special type of diabetic coma);
• hyperlactic acidemia (increased levels of lactic acid in the blood in diabetes mellitus).

Caution is necessary when administering glucose solution to patients with chronic renal failure, hyponatremia and decompensated chronic heart failure.

The use of glucose during pregnancy and breastfeeding is permitted. It should be remembered that in women bearing children, the level of glucose in the urine rises, which is due to hyperglycemia and relatively insufficient insulin production. In order to prevent the development of diabetes mellitus, it is necessary to closely monitor glucose fluctuations during pregnancy.

Additional Information

Glucose should be stored at air temperatures from 15 0 C to 25 0 C. The shelf life of the drug depends on the form of release - from 2 to 10 years.

Glucose tablets 0.5 g 10 pcs.

Glucose 500 mg No. 20 tablets

Glucose solution for infusion 5% 200 ml

Glucose solution for inf 10% 200 ml bottle

Glucose solution for infusion 5% 400 ml

Glucose solution 5% 200 ml

Glucose 5% solution for infusion 200ml No. 1 bottle /Mospharm/

Information about the drug is generalized, provided for informational purposes and does not replace official instructions. Self-medication is dangerous to health!

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Glucose - indications and contraindications for its use

So, what are the indications for the use of this medication?

The solution of this drug can be of two types - hypertonic and isotonic solution. Both of these solutions are used in medical practice. If we talk about an isotonic solution, then with its help it is possible to restore the functioning of certain organs, as well as enrich the body with the necessary amount of fluid. Using a hypertonic solution, you can enhance metabolic processes, dilate blood vessels, increase diuresis, improve liver function, and so on.

Glucose is strictly contraindicated for patients with diabetes. In addition, it should never be prescribed to people with hyperglycemia. In both of these cases, an isotonic sodium chloride solution is used to dilute pharmaceuticals.

Manufacturer: JSC "Farmak" Ukraine

ATS code: B05BA03

Farm group:

Release form: Liquid dosage forms. Injection.

General characteristics. Compound:

Pharmacological properties:

Indications for use:

Directions for use and dosage:

Features of application:

Interaction with other drugs:

Contraindications:

Overdose:

Storage conditions:

Best before date. 5 years. Do not use the drug after the expiration date indicated on the package. Store at a temperature not exceeding 25 ºС. Keep out of the reach of children.

Vacation conditions:

On prescription

Package:

10 ml or 20 ml in an ampoule. 5 or 10 ampoules per pack. 5 ampoules in a blister, 1 or 2 blisters in a pack.

Glucose is the body's source of energy and its main nutrient. During pregnancy, a woman's blood glucose levels change. Its concentration and quantity are controlled by hormones (the main one is insulin). Due to disruption of hormonal levels, a person may develop certain diseases. During pregnancy, the glucose norm is 3.3 – 6.6 mmol/l. It is necessary to constantly monitor its fluctuations in the blood, since it is at this time that the level of amino acids decreases and the level of ketone bodies increases, which can trigger the onset of diabetes.

Application of Glucose

Glucose is used to remove toxins from the body and replenish fluid loss. In medicine, isotonic (for subcutaneous, intravenous, rectal) and hypertonic (for intravenous) solutions are used. A hypertonic solution dilates blood vessels, increases urine volume and enhances the activity of the heart muscle. Isotonic – replenishes fluid and serves as a source of nutrients. This drug is also used for the preparation of drug solutions for intravenous administration and as a component of blood replacement and anti-shock fluids. Glucose in the form of tablets is taken 0.5-1 grams at a time.

Intravenous glucose administration

Intravenous injections of glucose are administered by drip of 7 ml per 1 minute. The daily dose of the drug and the number of injections are determined by the doctor. A 5% solution of the drug should be administered no more than 400 ml per hour and no more than 2 liters per day. With a solution concentration of 10%, the injection rate is 3 ml per minute, and the daily dose is no more than 1 liter. The 20% solution should be administered very slowly, 2 ml per minute and no more than 500 ml per day. 40% glucose must be mixed with 1% ascorbic acid. Injections under the skin can be administered independently; for this you will need an isotonic solution of the drug and a syringe for hypodermic injections. Inject 400-500 ml per day into different places on the skin.

Analysis (test) for blood glucose levels

Before going to donate blood to determine your glucose level, you must not eat 8 hours before the procedure, that is, go on an empty stomach. It is also important not to be nervous before taking the test and not to overload yourself with physical work. The rest is up to specialists. There are three methods of glucose analysis: reductometric, enzymatic and based on color reactions with certain products. There is also a device called a glucometer, which allows you to measure the amount of sugar in your blood at home. To do this, you need to apply just one drop of blood to the test strip.