Hemodesis dropper: what is it prescribed for, drug analogues, instructions for use, indications. Hemodez-N - why is the Hemodez-N drip prescribed: side effects

Hemodez is a drug that exhibits a detoxification effect due to the polyvinylpyrrolidone included in its composition, which promotes the binding and rapid elimination of toxins circulating in the blood.

The drug Hemodez N differs from Hemodez in containing a lower molecular weight of povidone (polyvinylpyrrolidone), which significantly increases its detoxification abilities and increases the rate of excretion from the body by the kidneys. Due to the activation of renal blood flow by Hemodez N, glomerular filtration increases, and diuresis also increases. The drug is not metabolized and is completely eliminated from the body within 24 hours.

Release form and composition

Hemodez is produced in the form of a transparent yellowish infusion solution, in special bottles for blood substitutes of 100, 200 and 400 ml. The solution contains ions: calcium chloride, potassium chloride, sodium bicarbonate, sodium chloride, magnesium chloride, povidone with a molecular weight of 8000±2000 for Hemodez N and with a mass of 12,600±2700 for its analogue. The solution also contains water for injection as an excipient.

Indications for use of Hemodez according to the instructions

According to the instructions, Hemodez is indicated for:

• State of shock - postoperative, post-traumatic, burn, hemorrhagic;

• Intoxication in acute gastrointestinal diseases - dyspepsia, dysentery, salmonellosis;
• Liver lesions, which are accompanied by the development of liver failure;
• Pneumonia;
• Burn disease;
• Sepsis;
• Acute radiation sickness;
• Intrauterine infections;
• Hemolytic disease in newborns.

An infusion solution is also used for toxicosis in pregnant women, chronic liver diseases, thyrotoxicosis, and alcohol intoxication.

Methods of using Hemodez

According to the instructions, Hemodez is administered intravenously at a rate of 40-80 drops per minute, a device with a filter is used for infusions, and the prescribed single dose of the medicine depends on the age of the patient and the severity of the toxin damage. Before use, the drug must be brought to body temperature (35-36°C), a single dose for adults is 200-500 ml, for children - 5-10 ml per 1 kg of body weight. The intervals between injections of the solution should be at least 12 hours. The maximum single dose of Hemodez for adults is 500 ml, for children:

• From 10 to 15 years – 200 ml;
• From 5 to 10 years – 150 ml;
• From 2 to 5 years – 100 ml;
• Infant age – 50-70 ml.

Hemodez can be administered once or 2 times a day.

The course of therapy lasts from 1 to 10 days, depending on the patient’s condition and the severity of the disease:

• In case of burn or radiation disease, acute gastrointestinal diseases with severe symptoms of intoxication, 1-2 infusions per day are given;
• For manifestations of neonatal toxemia, as well as hemolytic disease, the drug is administered 2-8 times, one or two infusions per day (daily or every other day);
• In case of large-focal infarction, during the first day Hemodez is administered once in an amount of 200 ml, the same dosage is prescribed on the second day in case of complications (cardiogenic shock, severe arrhythmia).

If necessary, subcutaneous administration of the drug is also possible, but in this case the effectiveness of the effect is reduced.

Contraindications to the use of Hemodez

As stated in the instructions, Hemodez is contraindicated for:

• Hypersensitivity to the components of the drug;
• Brain hemorrhage;
• Cardiovascular failure;
• Acute jades;
• Thromboembolism;
• Bronchial asthma;
• Oliguria;
• Anuria;
• Intracranial hypertension;
• Phlebothrombosis.

Side effects

When administered slowly, as shown in the instructions, the drug usually does not cause any side effects. When Hemodez is infused at a higher rate, a decrease in blood pressure, the occurrence of tachycardia, and difficulty breathing can be provoked. In such cases, the administration of the drug is stopped and symptomatic therapy is carried out.

special instructions

The use of Hemodez is possible with the simultaneous use of albumin and gamma globulin for extensive burns. The drug can be used only if its packaging is intact; upon visual inspection of the liquid in the bottle, it should not contain suspensions or sediment.

Composition and action for blood purification

The solution contains chlorides of potassium, calcium, sodium, magnesium, sodium bicarbonate, low molecular weight povidone (in the line of drugs it has a different molar mass). If there is no medicine, the doctor will prescribe Neohemodez, a substitute medicine with a similar composition.

Action of the drug:

1. The active substance (low molecular weight povidone) binds toxins circulating in the blood and removes them.
2. Does not allow stasis of red blood cells (means a temporary stop in blood flow). A condition that occurs in cancer patients, alcohol poisoning.
3. Increases diuresis, improves the filtration function of the kidneys.

In some cases, the Hemodez dropper is used in conjunction with albumin and gamma globulin.

What is it prescribed for and the form of release

The solution is released in bottles with a yellowish liquid of 100, 200, 400 ml. It is not available in the form of tablets or injections.

Indications for the use of hemodez:

• infectious lesions: salmonellosis, dysentery, rotavirus infections;
• poisoning with chemicals (industrial and household chemicals, alkalis, acids);
• medication overdose;
• shock conditions due to burns, injuries, blood loss;
• chemotherapy, oncology;
• liver diseases, liver failure;
• radiation sickness;
• alcohol intoxication;
• myocardial infarction;
• pneumonia;
• toxicosis of pregnant women in late stages (preeclampsia);
• hemolytic disease;
• peritonitis, sepsis, psoriasis.

There are no age restrictions for using the medicine. The medication is used according to indications in newborns and for intrauterine infections. Treatment with the drug should be carried out for no more than 10 days.

Before use, check the integrity of the packaging. The solution is transparent yellowish, without sediment.

Indications for use for blood cleansing

The drug is administered intravenously. Treatment is carried out under the supervision of medical professionals.

Infusion can be used depending on the severity of the patient's condition 1 - 2 times a day. The maximum single dose of Hemodez dropper for adults is 400 ml, for children - depending on weight, 2.5 ml/kg. For children under 2 years of age, the dosage should not exceed 50 ml. The medication is administered systematically at intervals of 12 hours.

Heat the solution to 36-37°C. The rate of infusion of the medicine is 40 - 80 drops per minute.

The drug is used only intravenously, it is contraindicated to take orally, drink, or dilute with other liquids.

Difference between Hemodez and Hemodez N

Hemodez N is characterized by a lower molecular weight of povidone. Unlike the first, it is excreted faster by the kidneys and has a detoxifying effect.

Since 2005, Hemodez has been banned in pharmacology and medicine in the Russian Federation; analogues are used instead. The product is currently discontinued.

What information is missing from the article?

• More drug analogues
• Contraindications for concomitant diseases
• Dosage of the drug
• When will the effect of use be noticeable?
• What drugs should not be combined with?

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Release form and composition

Dosage form: solution for infusion - a transparent liquid of yellow or light yellow color (100, 200, 250, 400 or 500 ml in bottles, 100, 250 or 500 ml in containers, 250 or 400 ml in bottles, in cardboard pack – 1 piece; in a cardboard box – 28 bottles of 250 ml, 28 bottles of 200 ml, 15 bottles or bottles of 400 ml).

• Low molecular weight medical povidone (polyvinylpyrrolidone) with a molecular weight of 8000+-2000 – 6000 mg;
• Sodium chloride – 550 mg;
• Calcium chloride – 50 mg;
• Potassium chloride – 42 mg;
• Sodium bicarbonate – 23 mg;
• Magnesium chloride anhydrous – 0.5 mg.

Excipients: water for injection.

Indications for use

The detoxification effect of Gemodez-N is used in the treatment of the following pathologies:

• Intoxication (toxic diseases of the gastrointestinal tract (GIT), including dyspepsia, dysentery, salmonellosis; radiation, burn and hemolytic diseases, intestinal obstruction, peritonitis, sepsis, thyrotoxicosis, liver disease, pneumonia; myocardial infarction in the acute phase) ;
• Shock (postoperative, post-traumatic, burn, hemorrhagic);
• Preeclampsia;
• Toxemia of newborns.

Contraindications

Contraindications to the use of the drug are:

• Chronic heart failure stage IIB-III;
• Hemorrhagic stroke;
• Intracranial hypertension;
• Condition after traumatic brain injury;
• Respiratory failure;
• Bronchial asthma;
• Severe allergic reactions;
• Acute nephritis, oliguria, anuria;
• Phlebothrombosis;
• Thromboembolism;
• Hypersensitivity to the components of the drug.

Directions for use and dosage

The solution is administered intravenously at a rate of 40-80 drops per minute using a filter device.

Before the procedure, the solution must be warmed to body temperature.

The doctor prescribes dosage individually, taking into account the degree of intoxication and the patient’s age.

A single dose for adults is 200-500 ml, for children at the rate of 5-10 ml per 1 kg of child weight.

The maximum single dose for children, depending on age, should not exceed:

• Up to 2 years – 50-70 ml;
• From 2 to 5 years – 100 ml;
• From 5 to 10 years – 150 ml;
• For teenagers from 10 to 15 years – 200 ml.

The drug is administered 1-2 times a day for 1-10 days, depending on the degree of poisoning:

• Hemolytic disease and toxemia of newborns - every other day or daily for 2-8 procedures;
• Large-focal myocardial infarction - on the first day, 200 ml of the drug is administered once; if necessary, the infusion can be repeated the next day in the same volume;
• Acute gastrointestinal infections, burns and radiation sickness - 1-2 times a day.

When administering the solution, it is necessary to monitor the general condition and blood pressure of the patient.

Side effects

At a high rate of drug administration, side effects may occur in the form of difficulty breathing, arterial hypotension, and tachycardia.

In some cases, the effect of Hemodez-N can cause the development of allergic reactions, including anaphylactic shock.

special instructions

Freezing does not affect the quality of the drug; after thawing at room temperature, the contents should be shaken thoroughly before use.

Drug interactions

There is no information on drug interactions between the drug.

Analogues

Analogs of Hemodez-N are: Hemodez-8000, Neogemodez, Krasgemodez 8000, Alburex, Albumin, Gelofusin, Dextran, Volekam, Plasmalin, Poliglyukin, Reopoliglyukin, Refortan, Stabizol.

Terms and conditions of storage

Store out of the reach of children at a temperature of 0 to 20 °C.

Shelf life – 3 years.

Conditions for dispensing from pharmacies

Dispensed by prescription.

Active substance

Potassium chloride + Calcium chloride + Magnesium chloride + Sodium bicarbonate + Sodium chloride + Povidone-8000 (Potassium chloride + Calcium chloride + Magnesium chloride + Sodium hydrocarbonate + Sodium chloride + Povidone 8000).

Release form and composition

Available in the form of a sterile water-salt solution. The drug is sold in sealed bottles of 400, 250, 200 and 100 ml.

Indications for use

Used for the following diseases and conditions:

• detoxification of the human body in case of toxic forms of various acute gastrointestinal diseases (salmonellosis, dysentery, intestinal obstruction, dyspepsia);
• various pathological conditions in adults and children, which are accompanied by symptoms of intoxication, including postoperative, radiation, cancer, and alcohol intoxication.

Use is indicated for toxicosis in patients with dysentery, toxicosis in pregnant women, for intoxication associated with renal and liver failure and chronic liver diseases (hepatochollangitis, hepatitis, liver dystrophy).

Contraindications

Contraindicated for the following diseases and conditions:

• acute nephritis,
• bronchial asthma,
• cardiovascular insufficiency stage II-III,
• stroke,
• uncontrolled hypertension,
• anuria and oliguria,
• conditions after traumatic brain injury,
• severe allergic reactions,
• phlebothrombosis,
• respiratory failure,
• hypersensitivity to the components of the solution.

Instructions for use Hemodez (method and dosage)

Hemodez solution is administered intravenously by drip, the drug administration rate is 40-80 drops per minute. Subcutaneous infusion of the substance is acceptable, but the effectiveness of the effect is much lower.

Single dose for adults – 200-500 ml; for children – 5-10 ml/kg; the maximum single dose for infants is 50-70 ml, 2-5 years old - 100 ml, 5-10 years old - 150 ml, 10-15 years old - 200 ml.

Hemodez is administered once or repeatedly (up to 2 times a day) for 1-10 days, depending on the severity of intoxication.

For acute gastrointestinal infections, burn and radiation diseases, administer 1-2 times a day; for hemolytic disease and toxemia of newborns - 2-8 times a day (daily or every other day); for large-focal myocardial infarction - 200 ml once, for complications on the 2nd day - 200 ml.

Side effects

The use of Hemodez solution with proper, slow intravenous drip administration, as a rule, does not cause any complications. Rapid administration of the drug can provoke a significant decrease in blood pressure, difficulty breathing, and tachycardia. Some patients develop severe allergic reactions, including anaphylactic shock.

If any side effect occurs, the infusion is stopped immediately and adequate symptomatic therapy is carried out using cardiac and vasoconstrictor drugs, calcium chloride, glucocorticoids, vasopressives, antihistamines and cardiotonic drugs.

Overdose

Overdose is unlikely.

Analogues of Hemodez

Analogs by ATX code: Volulight.

Do not decide to change the drug on your own; consult your doctor.

pharmachologic effect

special instructions

During pregnancy and breastfeeding

In childhood

Drug interactions

Hemodesis can be combined in complex therapy with other medications - polyglucin, various saline solutions, red blood cells, albumin. In acute renal failure resulting from surgery, the drug can be used in conjunction with osmotic diuretics (mannitol).

Conditions for dispensing from pharmacies

Dispensed by prescription.

Storage conditions and periods

Store at a temperature of +10…+20 °C. Freezing of the drug is unacceptable.

Shelf life – 5 years.

What is Hemodez?

Hemodez is a plasma-substituting drug that removes toxic substances from the body. It is used in the form of droppers and injections. Predecessor of Phys. solution. Visually presented in the form of a transparent liquid. Usually has a yellowish tint.

The composition includes a water-salt solution, including 6% polyvinylpyrrolidone with a low molecule content, sodium, potassium, calcium, magnesium, chlorine ions.

Combined with other medications. World non-proprietary name Povidone 12600. Popularly called blood sorbent.

On May 24, 2005, by order of the Federal Service for Healthcare Supervision, hemodez was prohibited for practical use in the Russian Federation. As a result, the production of this drug was stopped. To this day it is allowed in the Belarusian Republic. Instead, the drug Hemodez-N is produced in the Russian Federation. The difference from its predecessor is its lower molecular weight. This accelerates the release of toxic substances from the body.

Scope of application

• intestinal infections of any kind that poison the body (dysentery, intestinal obstruction);
• poisonings and disorders of the gastrointestinal tract, including alcohol intoxication;
• peritonitis;
• aggravated liver diseases;
• shock after injuries and surgery;
• burns;
• intrauterine diseases and toxicity of infants;
• gestosis of newborns;
• heart attack conditions, used as a means of combating arrhythmia;
• toxicosis of pregnant women.

Contraindications and side effects

• renal failure, nephritis;
• hypersensitivity to the components of the drug;
• diabetes;
• bronchial asthma;
• respiratory or cardiovascular failure;
• cerebral hemorrhage and other consequences of traumatic brain injury.

Attention! Be sure to tell your doctor if you have certain medical conditions or allergies. The most complete information will contribute to the correctness of the prescribed therapy. However, each body reacts to a particular administered substance differently. As a rule, slow administration of the drug Hemodez does not cause complications.

Possible side effects if administered incorrectly:

• disruption of the urinary system, development of enuresis;
• respiratory failure, tachycardia;
• blood pressure surges;
• allergies reaching the point of shock.

It was the side effects that caused the drug to be banned. There is also a theory about a small proportion of the drug in the composition of Hemodez. And it, in turn, becomes addictive with prolonged treatment.

There was an opinion that the positive effect of using the drug in the form of intravenous drips was due to the placebo effect. The interaction of Hemodez with alcohol has not been studied.

Compound

100 ml of the drug Hemodez N and Hemodez 8000 include:

• 6000 mg – medical low molecular weight povidone (polyvinylpyrrolidone) with a molecular weight of 8000±2000;
• 42 mg - potassium chloride;
• 550 mg - sodium chloride;
• 50 mg - calcium chloride;
• 500 mcg - anhydrous magnesium chloride;
• 23 mg - sodium bicarbonate.

Release form

The drug is available in the form of an infusion solution. Depending on the manufacturer, the solution is bottled in bottles of 100, 200, 250 or 400 ml.

pharmachologic effect

Detoxification, plasma replacement, antiaggregation.

Pharmacodynamics and pharmacokinetics

The effects of a drug are determined by the action of its main active substance - low molecular weight polyvinylpyrrolidone, which, after intravenous administration, binds toxins circulating in the bloodstream and promotes their rapid elimination from the body.

The molecular weight of polyvinylpyrrolidone in the preparations Hemodez N and Gemodez 8000, in contrast to the usual Hemodez, is significantly lower, and therefore their detoxification qualities are improved, and the time for elimination of toxins by the kidneys is reduced. The drugs increase glomerular filtration, renal blood flow and increase diuresis.

Polyvinylpyrrolidone is not metabolized in the human body and is fairly quickly excreted in the urine (a small part in feces). 80% of the drug is eliminated within 4 hours, the remaining 20% ​​within 12-24 hours.

Indications for use of Hemodez

Indications for use of Gemodez N and Gemodez 8000 are:

• state of shock due to burns, injuries, blood loss, as well as due to surgery;
• intoxication due to gastrointestinal diseases, including dyspepsia, dysentery and salmonellosis;
• intoxication during peritonitis in the postoperative period;
• liver pathologies with the formation of liver failure;
• thyrotoxicosis;
• intestinal obstruction;
• burn disease;
• sepsis;
• acute radiation sickness;
• pneumonia;
• hemolytic disease of newborns;
• myocardial infarction in the acute phase;
• toxicosis of pregnant women;
• toxemia of newborns and intrauterine infection.

Contraindications

• intracranial hypertension;
• hypersensitivity;
• condition after TBI;
• hemorrhagic stroke;
• allergic reactions (severe);
• cardiovascular failure (grade 2-3);
• respiratory failure;
• thromboembolism;
• anuria;
• oliguria;
• acute nephritis;
• phlebothrombosis;
• bronchial asthma;
• diabetes.

Side effects

As a rule, slow administration of the drug does not cause any complications.

In rare cases, the development of serious allergic manifestations, including anaphylactic shock, has been observed. In such cases, the infusion should be stopped immediately and symptomatic treatment should be carried out, which consists of the administration of cardiotonic and antihistamines, vasopressive drugs, and glucocorticoids.

Hemodez, instructions for use (Method and dosage)

Instructions for use of Gemodez 8000 and Gemodez N recommend administering the drugs only by drip (infusion), through a special transfusion system.

Doses of drugs are calculated based on the severity of intoxication, as well as the age of the patient. Infusions are carried out once or twice a day for 1 to 10 days.

For adult patients, depending on the condition and cause of intoxication, a single dose infusion of 200-500 ml is recommended.

The pediatric dose is calculated at the rate of 5-10 ml per kilogram of body weight.

• under 2 years of age - 50-70 ml;
• at the age of 2-5 years - 100 ml;
• at the age of 5-10 years - 150 ml;
• at the age of 10-15 years - 200 ml.

For burns, gastrointestinal infections and radiation sickness, administration is carried out 1-2 times in 24 hours.

For toxemia and hemolytic disease of newborns, infusions are carried out 2-8 times a day, every day or with a break of 24 hours.

In case of myocardial infarction (large-focal), a single drip of 200 ml is prescribed on the first day; in case of complications, it is repeated on the second day in the same volume.

Overdose

An overdose of Gemodez N and Gemodez 8000 is unlikely.

Interaction

Concomitant use with other drugs may lead to a decrease in their pharmacological effectiveness.

Terms of sale

Solutions Gemodez N and Gemodez 8000 are sold by prescription.

Storage conditions

Vials with the solution should be stored at temperatures up to 20 °C. Freezing drugs (down to -45 °C) does not reduce their quality.

Best before date

Both drugs remain effective for 3 years.

special instructions

Before infusing drugs, it is necessary to check the integrity and tightness of the primary packaging. Solution The drug should not contain foreign matter and be visually transparent.

Before infusion, the temperature of the drugs is brought to body temperature.

For burns on large areas of the body, Hemodez infusions are combined with the administration of albumin, plasma, and gamma globulin.

Analogues

Level 4 ATX code matches:

The most common analogues of Hemodez N and Gemodez 8000:

• Albumen;
• Alburex;
• Volekam;
• Gelofusin;
• dextran;
• Poliglyukin;
• Plasmalin;
• Reopoliglyukin;
• Refortan;
• Stabizol, etc.

Synonyms

• Hemodez;
• Neohemodesis;
• Krasgemodez 8000.

For children

Both drugs are used in accordance with the recommended doses and indications.

With alcohol

Gemodez 8000 and Gemodez N for alcohol poisoning are used directly to relieve alcohol intoxication. A single dose of one or the other drug is usually 400 ml with possible repetition after 12 hours. Therapy is carried out in a hospital setting, taking into account all contraindications and under the supervision of a doctor.

During pregnancy (and lactation)

If it is necessary to use it during breastfeeding, it must be stopped for the duration of therapy.

size d/inf.: fl. 200 ml 1 or 28 pcs., fl. 400 ml 1 or 15 pcs. Reg. No.: LS-001636

Clinical and pharmacological group:

A drug with a detoxification effect for parenteral use

Release form, composition and packaging

Solution for infusion transparent, light yellow or yellow.

Excipients: water d/i.
200 ml - bottles for blood substitutes (1) - cardboard packs.
200 ml - bottles for blood substitutes (28) - cardboard boxes.
400 ml - bottles for blood substitutes (1) - cardboard packs.
400 ml - bottles for blood substitutes (15) - cardboard boxes.

Description of the active components of the drug " Gemodez-n»

pharmachologic effect

A drug with a detoxifying effect. The mechanism of action is due to the ability of low molecular weight povidone to bind toxins circulating in the blood and quickly remove them from the body.

Hemodez-N increases renal blood flow, increases glomerular filtration and increases diuresis.

Gemodez-N differs from gemodez in the lower molecular weight of polyvinylpyrrolidone used for its manufacture. Reducing the molecular weight of the polymer accelerates its excretion from the body by the kidneys and improves the detoxification properties of the drug.

Indications

Detoxification therapy for:

—toxic forms of acute infectious intestinal diseases (dysentery, salmonellosis);

—peritonitis (in the postoperative period);

— liver diseases accompanied by the development of liver failure;

— burn disease;

-sepsis;

— hemolytic disease of newborns;

— intrauterine infection and toxemia of newborns.

Dosage regimen

Before administration, the solution should be warmed to body temperature.

The drug is administered intravenously at a rate of 40-80 drops/min. A single dose depends on the age of the patient and the severity of intoxication. Initial dose for children is 2.5 ml/kg body weight.

The maximum single dose depending on the patient’s age is presented in the table:

The drug is administered 1-2 times a day depending on the severity of intoxication.

Side effect

Maybe:(when administered at an increased rate) - arterial hypotension, tachycardia, difficulty breathing.

In some cases: allergic reactions up to anaphylactic shock.

Contraindications

- hemorrhagic stroke;

—cardiovascular failure;

- hypersensitivity to the drug.

Pregnancy and lactation

Data on the effectiveness and safety of the use of the drug Hemodez-N during pregnancy and lactation are not provided.

special instructions

If allergic reactions occur when administering the drug, you should immediately stop the infusion and carry out symptomatic therapy (antihistamines, cardiotonics, corticosteroids, vasoconstrictors).

The occurrence of adverse reactions when Hemodez-N is administered at an increased rate may require the administration of vasoconstrictor and cardiotonic drugs, calcium chloride.

Overdose

Data on overdose of the drug Gemodez-N are not provided.

Drug interactions

Storage conditions and periods

The drug should be stored out of the reach of children at a temperature of 0° to 20°C. Freezing of the drug and non-wetting of the inner surface of the bottles is not a contraindication to the use of the drug. Shelf life – 3 years.

Conditions for dispensing from pharmacies

The drug is available with a prescription. Intended for use in hospitals only.

Drug interactions

No drug interactions have been described.

Instructions for the drug Gemodez-N

The drug Hemodez is a solution for infusion that is capable of providing a detoxification effect.

Hemodez composition

A transparent solution with a yellow or light yellow color consists of povidone (polyvinylpyrrolidone), a low-molecular medical molecular weight of which is 8000±2000, as well as sodium chloride, potassium chloride, calcium chloride, anhydrous magnesium chloride, sodium bicarbonate, osmolarity in the required composition of the drug proportions. This entire complex of substances is supplemented with the required amount of injection water.

Hemodez shelf life and its conditions

The drug should be stored at temperatures from 0 to 20 degrees for no more than three years. Places where the drug is stored must be inaccessible to children.

The drug can be frozen, after which it does not lose its properties.

Pharmacology Gemodez (Gemodez-N)

The mechanisms of detoxification action of the drug Hemodez are due to the fact that low molecular weight povidone is capable of binding toxins circulating in the blood and quickly removing them from the body.

The version of the drug Gemodez-N, unlike Gemodez, contains polyvinylpyrrolidone, which has a lower molecular weight, which contributes to its faster elimination from the body by the kidneys and improves the detoxification properties of the drug. Hemodez-N also helps to increase renal blood flow, increase glomerular filtration and increase diuresis.

Hemodesis indications

The drug Hemodez is indicated for use for those patients who suffer from the following diseases:

• Toxic form of acute infectious intestinal disease (dysentery, salmonellosis);
• Peritonitis (in the period after surgery);
• Liver diseases, which are accompanied by the development of liver failure;
• Burn disease;
• Sepsis;
• Hemolytic disease of the newborn;
• Intrauterine infection and toxemia of the newborn.

Hemodesis contraindications

The drug Hemodez has contraindications when its use is undesirable for the patient. Hemodesis should not be prescribed:

• For hemorrhagic stroke;
• For cardiovascular failure;
• In case of hypersensitivity to the drug.

Hemodez instructions for use

Before using the solution for administration, it must be warmed to a state corresponding to body temperature.

Hemodesis intravenously

The use of Hemodez for treatment is permitted only under medical supervision in a hospital.

The drug is to be administered intravenously by drip. The rate of administration is from 40 to 80 drops per minute. Depending on the age of the patient and the severity of intoxication, the dosage of the drug for treatment is calculated.

For children, the initial dose is set at the rate of 2.5 milliliters per kilogram of body weight.

The drug is administered in the dose that will be determined once or twice a day, depending on the severity of the intoxication lesion.

Hemodesis dropper

There is a definition of the maximum single dose, beyond which it is unacceptable to go. When calculating the dosage, the guideline was based on age.

For adults, the maximum single dose should not exceed 400 milliliters.

For children from 10 to 15 years of age, the maximum single dose should not exceed 200 milliliters.

For children from 6 to 9 years of age, the maximum single dose should not exceed 100 milliliters.

For children from 2 to 5 years of age, the maximum single dose should not exceed 70 milliliters.

For children under 1 year of age, the maximum single dose should not exceed 50 milliliters.

Use of Hemodez during pregnancy

Data on how effective the drug is and whether its use is safe for a pregnant woman have not yet been provided.

Hemodesis side effects

If the rate of drug administration is exceeded, conditions of arterial hypotension, tachycardia may occur, and the patient may experience difficulty breathing.

Sometimes allergies and even anaphylactic shock may occur.

Overdose

Data on cases of overdose with Gemodez (Gemodez-N) have not been reported.

Drug interactions Hemodez

There are no descriptions of drug interactions with the drug Hemodez (Hemodez-N).

Additional instructions

If an allergic reaction occurs during the administration of the drug, the infusion should be interrupted and the patient should be treated with symptomatic therapy.

When side effects occur due to a violation of the rate of solution administration, it is necessary to administer a vasoconstrictor and cardiotonic drug.

Hemodez analogues

Analogues of the drug Hemodez are solutions Neogemodez, Krasgemodez 8000, as well as Hemodez 8000, which can successfully replace Hemodez if necessary.

Hemodez price

The drug Hemodez is inexpensive. Its cost varies depending on the volume of the bottle from 57 to 125 rubles.

Gemodez reviews

There are few reviews about the drug, but they all indicate the good cleaning ability of the drug. Those who have experienced the beauty of alcohol poisoning are grateful to the drug for its help. There are also those who, with its help, managed to cleanse the body of drugs. In a word, the drug is able to cleanse the body of a wide variety of toxic contaminants.

Anatoly: The drug Hemodez was received in the form of droppers after removal of purulent appendicitis. I remember that I quickly improved. So, Gemodez saved me from terrible consequences. I can give the drug a positive assessment.

Viktor Sergeevich: I had to use Hemodez only once, when I was hospitalized with severe intoxication from low-quality alcohol. However, two droppers in a day got me back on my feet. The drug is what you need.

Zhanna: One day I got food poisoning, which was caused by seemingly decent canned fish. At first I tried to help myself with activated carbon. However, by morning I realized that things were bad and called an ambulance. At the hospital I received help fairly quickly. As far as I understood then in my semi-conscious state, the main culprit in my salvation was the dropper with the drug Hemodez. Well, what can I say, the drug has five stars, which it well deserves.

Similar instructions:

Effective infusion therapy is the key to successful treatment of various pathologies and diseases. And Hemodez is an effective detoxification agent that is very popular and effective in modern medicine. It is necessary to pay attention to the fact that this drug is a plasma replacement agent.

Hemodez: composition and release form

Hemodez is available in the form of a solution that is yellowish in color. Concerning release forms, then the drug is produced in special bottles with different volumes. So, you can buy either a small bottle of 100 ml or a large bottle of 400 ml. A special one is used as an additional component.

What are the indications for use?

It should be noted that Hemodez is used for such clinical conditions as:

1. Post-traumatic, postoperative and burn shock.
2. Intoxication in acute gastrointestinal diseases.
3. Pneumonia.
4. Sepsis.
5. Burn diseases.

The infusion solution is used for toxicosis in pregnant women and for liver diseases that are chronic. And also with severe alcohol intoxication.

Instructions for use of the drug

The drug is administered intravenously using a dropper. Drug administration rates ranges from 40 to 80 drops per minute. The substance can also be administered subcutaneously, but the drug becomes less effective. Before use, the solution should be warmed to 35°C.

If we talk about dosage, then about 300-500 ml is administered to an adult patient once. If we are talking about a child, then the calculation of the amount of the drug depends on how much the child weighs. For one kilogram of the child’s body weight, take from 5 to 15 ml of solution.

The procedure can be repeated only after 12 hours. Please note that the dose and number of infusions should be determined by the doctor involved in the treatment. The procedure can be either a one-time procedure or a whole course of therapy, which consists of a maximum of 10 days of treatment. In case of burn disease and acute forms of the gastrointestinal tract with pronounced symptoms of intoxication of the body, the solution may be prescribed once or twice a day. This drug is used for toxemia in newborns. In this case, the doctor may prescribe from 2 to 8 droppers.

According to instructions for a large lesion, about 200 ml of solution is injected on the first day. If a long painful attack is observed, and a severe arrhythmia occurs, then on the second day another dropper of the drug is administered with the same dosage.

Hemodez: contraindications

Composition of the drug determines all contraindications to the use of the drug. Thus, Hemodez is prohibited from being used in the following cases:

• if a person has acute nephritis or bronchial asthma;
• the drug cannot be used for heart failure, stroke, or respiratory failure;
• Hemodesis should not be used after traumatic brain injury.

What side effects of the drug may occur?

It should be noted that rapid administration of the drug can provoke a rapid decrease in blood pressure, tachycardia, and breathing problems. In rare cases, the patient may experience severe allergic reaction, which can even end in anaphylactic shock.

If you notice at least one side effect of the drug, you should immediately stop taking it and begin symptomatic therapy. It should be noted that symptomatic therapy should be supported by cardiac and vasoconstrictor drugs.

How Hemodez is combined with other drugs, its analogues and price

This drug is great for complex therapy. It can be combined with different saline solutions and red blood cell mass. If acute renal failure occurs, then Hemodez is taken in conjunction with osmotic diuretics.

There are such analogues of Hemodez:

1. Neohemodesis.
2. Hemodez 8000.
3. Krasgemodez 8000.

The price of this medicine will directly depend on the size of the bottle. The price in Russia for Hemodez varies from 57 to 125 rubles.

Drug Hemodez

Gemodez: reviews

Just a month ago I received severe poisoning. The cause was normal-looking mussels. The first day I tried to act on my own: I took activated charcoal and drank a lot of liquid. However, this terrible condition did not go away and I consulted a doctor. It was at the hospital that I was given an IV with Hemodez, which put me back on my feet and removed all toxins from the blood. The lesson has been learned - it is better to immediately seek qualified help.

Marta, Volgograd

I was given a drip with Hemodez only once, when I was severely intoxicated with low-quality alcohol. I felt the effect of this medicine very quickly. It was this that helped put me back on my feet within a couple of days, and also cleansed my blood of harmful toxins that were in alcohol.

Victor, Moscow

Just recently I had purulent appendicitis removed and I received hemodesis in the form of droppers. It was this drug that helped me avoid various side effects. In addition, I recovered very quickly. Now I got out of the hospital and decided to write a positive review in Gemodez so that other people would know about it.

Nikolay, Murmansk

Hemodez is a water-salt solution, a colloid, used for detoxification of various types: infectious, oncological, radiation. Hemodez solution belongs to the group of plasma-substituting agents for intravenous administration and placement of droppers. There are 3 types of the drug for sale. The difference lies in the different molecular weight of the main component of the drug.

The solution contains chlorides of potassium, calcium, sodium, magnesium, sodium bicarbonate, low molecular weight povidone (in the line of drugs it has a different molar mass). If there is no medicine, the doctor will prescribe Neohemodez, a substitute medicine with a similar composition.

Action of the drug:

1. The active substance (low molecular weight povidone) binds toxins circulating in the blood and removes them.
2. Does not allow stasis of red blood cells (means a temporary stop in blood flow). A condition that occurs in cancer patients, alcohol poisoning.
3. Increases diuresis, improves the filtration function of the kidneys.

In some cases, the Hemodez dropper is used in conjunction with albumin and gamma globulin.

What is it prescribed for and the form of release

The solution is released in bottles with a yellowish liquid of 100, 200, 400 ml. It is not available in the form of tablets or injections.

Indications for the use of hemodez:

• infectious lesions: salmonellosis, dysentery, rotavirus infections;
• poisoning with chemicals (industrial and household chemicals, alkalis, acids);
• medication overdose;
• shock conditions due to burns, injuries, blood loss;
• chemotherapy, oncology;
• liver diseases, liver failure;
• radiation sickness;
• alcohol intoxication;
• myocardial infarction;
• pneumonia;
• toxicosis of pregnant women in late stages (preeclampsia);
• hemolytic disease;
• peritonitis, sepsis, psoriasis.

There are no age restrictions for using the medicine. The medication is used according to indications in newborns and for intrauterine infections. Treatment with the drug should be carried out for no more than 10 days.

Before use, check the integrity of the packaging. The solution is transparent yellowish, without sediment.

Indications for use for blood cleansing

The drug is administered intravenously. Treatment is carried out under the supervision of medical professionals.

Infusion can be used depending on the severity of the patient's condition 1 - 2 times a day. The maximum single dose of Hemodez dropper for adults is 400 ml, for children - depending on weight, 2.5 ml/kg. For children under 2 years of age, the dosage should not exceed 50 ml. The medication is administered systematically at intervals of 12 hours.

Heat the solution to 36-37°C. The rate of infusion of the medicine is 40 - 80 drops per minute.

The drug is used only intravenously, it is contraindicated to take orally, drink, or dilute with other liquids.

Difference between Hemodez and Hemodez N

Hemodez N is characterized by a lower molecular weight of povidone. Unlike the first, it is excreted faster by the kidneys and has a detoxifying effect.

Since 2005, Hemodez has been banned in pharmacology and medicine in the Russian Federation; analogues are used instead. The product is currently discontinued.

Analogues of Hemodez for blood cleansing

The listed medications are sold in pharmacies. Use as prescribed by a doctor; the drug is dispensed from pharmacies according to a prescription.

Contraindications and side effects

Before using the medication, read the instructions. Tell your doctor about any drug allergies.

Contraindications:

• increased intracranial pressure;
• hypertension;
• stroke, cerebral hemorrhage;
• CHF IIb - III degree;
• acute nephritis;
• thromboembolism;
• respiratory failure, asthma;
• oliguria, anuria;
• diabetes;
• individual intolerance;
• Use with caution during pregnancy and lactation, hormonal imbalance.

When the medicine is used correctly, there are no side effects. If the rate of drug administration is exceeded, hypotension, increased breathing, and arrhythmia are likely. No overdoses were observed.

Individual intolerance to the drug causes anaphylactic shock. Treatment is to stop using the medication, administer Prednisolone and adrenaline intravenously. Allergic reactions to the drug require the appointment of Hemodez substitutes.

Modern treatment is carried out with analogues of the drug. The medications mentioned are inexpensive and have no side effects.