What diseases does Trichopolum treat? What are Trichopolum tablets used to treat? Application in gynecology and urology, treatment of STDs

Trichopolum is a drug that belongs to the category of antimicrobial and antiprotozoal drugs and is highly effective in the treatment of many bacterial infections. In most
cases, the pharmacological agent is well tolerated by the human body and does not cause negative reactions. But, since Trichopolum has a wide list of contraindications for use, before using it you should definitely read the manufacturer’s instructions.

Trichopolum. Release form

The antibacterial pharmacological agent Trichopolum is presented on the market in tablet form, in the form of vaginal suppositories and a solution for external application. Tablets are whitish or yellow in color, elongated, elongated in shape, packaged in blister packs and cardboard packs. The pack contains 10 tablets.
Trichopolum in medicinal solution form is produced in glass bottles of 100 ml, as well as ampoules with a dosage of 20 ml. The color of the medicine varies from clear to yellow-green.

Trichopolum composition

The active substance contained in the medicine and ensuring its pharmacological effectiveness is metronidazole. It has a detrimental effect on many simple organisms, including aerobes and anaerobes. A Trichopolum capsule contains 250 mg of metronidazole. 100 ml of product for external application contains 500 mg of the main component. Other ingredients contained: sodium hydrogen phosphate, citric acid monohydrate, sodium chloride, distilled water.
Gynecological suppositories are packaged in aluminum blisters; one suppository contains 500 mg of active metronidazole.

What does Trichopolum treat?

Trichopolum belongs to the category of pharmacological agents used to treat pathologies of infectious-inflammatory origin, provoked by pathogens with sensitivity to the drug.
The main indications for the use of Trichopolum:

  1. Vaginosis of bacterial nature.
  2. Nonspecific vaginitis, other gynecological diseases.
  3. Trichomoniasis.
  4. Giardiasis.
  5. Infections caused by the bacterium Helicobacter pylori.
  6. Peritonitis.
  7. Hepatic and intestinal amebiasis, which occurs in severe form.
  8. Gas gangrene.
  9. Abscesses in the brain, pelvis or other internal organs.
  10. Sepsis.

Trichopolum - what does it treat? This question arises for many patients who are prescribed this pharmacological drug. The instructions from the manufacturer emphasize that the drug is widely used in the treatment of many gynecological pathologies caused by microorganisms sensitive to Trichopolum.
The pharmacological drug belongs to the group of nitro-5-imidazoles with pronounced antiprotozoal and antibacterial properties. Trichopolum actively affects the DNA of the cells of microorganisms that are causative agents of infectious and inflammatory diseases. This leads to their gradual destruction.

Trichopolum instructions for use

If a patient is prescribed Trichopolum, the instructions for use emphasize that the method of taking the drug depends on the specific disease, age and gender of the patient, as well as the individual characteristics of the body.

: depending on the severity of the disease, the patient may be prescribed Trichopolum 1 tablet three times a day or 2 tablets twice a day. After this, you should take a break from treatment for 4 weeks, after which, if necessary, continue therapy. Additionally, vaginal suppositories with antibacterial properties may be prescribed.

Amebiasis: treatment of the pathology consists of taking 3 tablets of the drug three times a day, the duration of the treatment course varies between 5-6 days.

If vaginal suppositories are used to treat gynecological diseases, it is recommended to dip them in water before use and then insert them as deep as possible into the vagina. It is not recommended to use medicinal suppositories more than 3 times every 12 months. For gynecological diseases, additional treatment of the sexual partner is not necessary.

The medicinal solution is used for intravenous injections. The dosage and frequency of administration are determined by the doctor individually for each patient.

Contraindications for use

The drug has several contraindications for use, so be sure to carefully read the instructions before using it.
The main contraindications to taking Trichopolum:

  • all trimesters of pregnancy and breastfeeding;
  • renal and liver failure;
  • pathologies in the functioning of the brain and nervous system;
  • presence of epilepsy;
  • leukopenia;
  • individual intolerance to the active ingredients included in the drug.

In such cases, it is recommended to abandon the use of Trichopolum or replace it with a pharmacological agent with a similar principle of action.
The drug is prohibited for use during the first trimester of pregnancy and breastfeeding. Taking Trichopolum in the second and third trimester is permitted only as prescribed by a doctor, under his strict supervision, and only in cases where there is a serious risk to the life and health of the expectant mother.

Breastfeeding women are also not recommended to use the drug. The active substances contained in Trichopolum penetrate into breast milk, after which they enter the child’s body. If you use the medication, you will have to stop breastfeeding. You can return to lactation no earlier than 2 days after completing the course of treatment with Trichopolum.

Trichopolum is prohibited for use in the treatment of children under 3 years of age. While taking the medication, it is strictly forbidden to drink any alcoholic beverages, since in combination with alcohol, the medicine can cause unwanted side effects.

Tablets or vaginal suppositories must be used regardless of the menstrual cycle - this means that the course of treatment should not be stopped even during menstruation. But the manufacturer emphasizes that it is best to avoid intimate relationships during therapy.

Side effects

In rare cases, taking Trichopolum can provoke side effects in the form of loss of appetite, attacks of nausea and vomiting, and stool disorders. Also, the use of the drug can cause the development of anorexia, severe headaches and dizziness.
During treatment with Trichopolum, the patient may notice such unpleasant consequences as confusion, sudden mood swings from excitement to depression, depression, weakness, loss of strength, sleep disturbances - from constant drowsiness to insomnia.

In extremely rare situations, Trichopolum can cause side effects in the form of increased body temperature, thrush of the oral cavity or genitals, discomfort, burning and itching in the urinary tract, allergic rashes on the skin of the face or body.
Also, the use of Trichopolum tablets can cause urine to turn brown or red, which is the result of the metabolism of the active component metronidazole.
To date, no cases of overdose of this drug have been recorded in medical practice.

Trichopolum price

Trichopolum is one of the inexpensive drugs. Its cost, depending on the pharmacy chain, varies between 80-150 rubles. The medication is dispensed only with a medical prescription.

Trichopolum analogues

In case of individual intolerance to Trichopolum, it can be replaced with a drug with a similar principle of action. The main active ingredient in the medication is metronidazole. Its analogues include drugs that also contain this component.
The main analogues of Trichopolum:

  1. Metronidazole.
  2. Trichosept.
  3. Orvagil.
  4. Klion.
  5. Flagyl.
  6. Metroseptol.
  7. Batsimex.
  8. Deflamon.
  9. Rosex.
  10. Trichobrol.

The decision to replace a drug and choose an analogue should be made only by the attending physician, based on the severity and individual characteristics of the development of the disease.
Trichopolum is an effective medication with pronounced antibacterial and antiprotozoal properties. Experts emphasize that the medicine can be combined with antibiotics, as well as drugs from the category of sulfonamides.

Also, Trichopolum should not be taken simultaneously with medications from the category of anticoagulants and muscle relaxants. This significantly enhances the effect of pharmacological agents.
One of the main side effects of the drug is the appearance of severe headaches, attacks of dizziness and confusion. Therefore, during treatment with Trichopolum, it is strictly not recommended to drive vehicles or complex production mechanisms, as this can be dangerous to human life.

In most cases, Trichopol tablets and vaginal suppositories are well tolerated by the human body and do not cause side effects - they develop only in rare cases.

Trichopolum reviews

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Trichopolum is an antiprotozoal and antimicrobial drug. It has been successfully used to treat certain types of bacterial infections.

Trichopolum can be taken orally or applied to the skin; the choice of method of application depends on the type of infection. Trichopolum is usually well tolerated and does not cause serious side effects, but the instructions must be studied before use.

In this article we will look at why doctors prescribe the drug Trichopolum, including instructions for use, analogues and prices for this drug in pharmacies. If you have already used Trichopolum, leave your feedback in the comments.

Composition and release form

The drug Trichopolum is available in tablets and solution form:

  1. According to the instructions, one tablet of Trichopolum contains 250 mg of metronidazole, available in cellular packaging in packs of 10 pieces.
  2. One 100 ml bottle of Trichopolum contains 500 mg of metronidazole, available in 100 ml polyethylene bottles.
  3. One 20 ml ampoule of a transparent, yellowish-green drug contains metronidazole 500 mg, sodium hydrogen phosphate, citric acid monohydrate, sodium chloride, water for injection, available in 10 ampoules in cardboard packs.

Clinical and pharmacological group: antiprotozoal drug with antibacterial activity.

What does Trichopolum treat?

Trichopolum is indicated for infectious and inflammatory diseases caused by microorganisms sensitive to the drug, and therefore to treat the following diseases:

  • trichomoniasis;
  • bacterial vaginosis;
  • giardiasis;
  • periodontal infections (including acute ulcerative gingivitis, acute odontogenic infections);
  • anaerobes sensitive to metronidazole;
  • all forms of amebiasis (diseases of intestinal and extraintestinal localization, including amoebic liver abscess, amoebic dysentery, as well as asymptomatic amebiasis);
  • anaerobic bacterial infections (gynecological and abdominal infections of the central nervous system, bacteremia, sepsis, endocarditis, infections of bones and joints, skin and soft tissues, respiratory tract infections) caused by Bacteroides spp., Clostridium spp., Eubacterium spp., Peptococcus spp., Peptostreptococcus spp. .
  • treatment of Helicobacter pylori infections in gastric or duodenal ulcers in combination with bismuth preparations and an antibiotic, for example, amoxicillin.

Prophylactic prescription before surgery on the gastrointestinal tract and reproductive organs.

Pharmacodynamics

Antiprotozoal drug with antibacterial activity for topical use in gynecology. Refers to nitro-5-imidazoles.

The mechanism of action of metronidazole is the biochemical reduction of the 5-nitro group of metronidazole by intracellular transport proteins of anaerobic microorganisms and protozoa.

The reduced 5-nitro group of metronidazole interacts with the DNA of the cell of microorganisms, inhibiting the synthesis of their nucleic acids, which leads to the death of microorganisms. Metronidazole is an effective antimicrobial and antiprotozoal agent with a broad spectrum of action.

Instructions for use

How to take this drug depends on what you are treating with Trichopolum, the form of the drug, and the age of the patient. The exact dosage is determined only by the attending physician.

  1. Bacterial vaginosis. Adults are prescribed 500 mg (2 tablets) 2 times/day for 7 days or 2000 mg (8 tablets)/day once. Simultaneous treatment of the sexual partner is not required.
  2. Trichomoniasis. Adults and children over 10 years of age are prescribed 250 mg (1 tablet) 3 times a day or 500 mg (2 tablets) 2 times a day for 7 days. Women must additionally be prescribed metronidazole in the form of vaginal suppositories or tablets. If necessary, you can repeat the course of treatment. Between courses you should take a break of 3-4 weeks with repeated control laboratory tests. An alternative treatment regimen is to prescribe 750 mg (3 tablets) in the morning and 1250 mg (5 tablets) in the evening or 2000 mg (8 tablets)/day once. The duration of treatment is 2 days. Treatment is carried out simultaneously for both sexual partners.
  3. Giardiasis. Adults and children over 10 years of age are prescribed 500 mg (2 tablets) 2 times a day for 5-7 days; or 2000 mg (8 tablets) 1 time/day for 3 days.
  4. Amoebiasis. For invasive forms of intestinal amebiasis in susceptible patients (including amoebic dysentery), adults and children over 10 years of age are prescribed 750 mg (3 tablets) 3 times a day. Children aged 3 to 7 years – 250 mg (1 tablet) 4 times a day; at the age of 7 to 10 years – 375 mg (1.5 tablets) 3 times a day. The course of treatment is usually 5 days.
  5. For intestinal amebiasis in less susceptible patients and in chronic amoebic hepatitis, adults and children over 10 years of age are prescribed 375 mg (1.5 tablets) 3 times a day. Children aged 3 to 7 years – 125 mg (1/2 tablet) 4 times a day; at the age of 7 to 10 years – 250 mg (1 tablet) 3 times a day. The duration of the course of treatment is 5-10 days.
  6. Helicobacter pylori eradication. Prescribe 500 mg (2 tablets) 3 times/day for 7 days (as part of combination therapy, for example, with amoxicillin 2.25 g/day). Prevention of infections caused by anaerobic bacteria (before surgical operations on the abdominal cavity, in gynecology and obstetrics).
  7. Periodontal infections. For acute ulcerative gingivitis, adults and children over 10 years of age are prescribed 250 mg (1 tablet) 3 times a day. Children aged 3 to 7 years – 125 mg (1/2 tablet) 2 times a day; at the age of 7 to 10 years – 125 mg (1 tablet) 3 times a day. The duration of treatment is 3 days.

Before use, vaginal suppositories must be moistened in water; one tablet is used once every 24 hours for no longer than 10 days. Treatment begins after menstruation, using suppositories with Trichopolum no more than three times a year, combined with the oral form of the drug and other medications.

For intravenous infusion, the maximum dose of Trichopolum should not exceed four grams, and for children it is set based on the child’s weight (7.5 ml per 1 kg of weight).

Contraindications for use

According to the instructions, Trichopolum is contraindicated for use when:

  1. Leukopenia;
  2. Kidney failure;
  3. Liver failure;
  4. Organic damage to the central nervous system;
  5. Hypersensitivity to the active component - metronidazole and its derivatives.
  6. During pregnancy and lactation.

Side effects

Use may have the following side effects: nausea, vomiting, abdominal pain, diarrhea, anorexia. An unpleasant metallic taste, headache, dizziness, mental fog, hyperexcitability, depression, drowsiness, insomnia, and weakness may occur.

Stomatitis, oral candidiasis, and fever are possible. And patients experienced allergic reactions: skin rashes, itching, burning and discomfort in the urinary tract, vaginal dryness, discoloration of urine, possible painful sensations during sexual intercourse, vaginal candidiasis.


Pregnancy and lactation

Metronidazole penetrates the placental barrier, therefore Trichopolum is contraindicated for use in the first trimester of pregnancy. The use of the drug in the second and third trimesters is possible only in cases where the expected benefit to the mother outweighs the potential risk to the fetus.

Since metronidazole is excreted in breast milk, reaching concentrations close to those in the blood plasma, if it is necessary to use Trichopolum during lactation, breastfeeding should be discontinued.

Use in childhood

The drug is contraindicated for use in children under 3 years of age. It is not recommended to use Trichopolum in combination with amoxicillin in children and adolescents under 18 years of age.

special instructions

During the course of therapy, you should refrain from even minimal alcohol consumption. When treating trichomonas infections of the genital organs, you must stop sexual activity for the duration of treatment; do not stop therapy during menstruation. The appearance of severe neurological symptoms while taking the drug is an indication for its discontinuation.

If pathological changes in the blood occur, the advisability of using Trichopolum should be reconsidered (taking into account the risk of infection and the risk of complications). If it is necessary to prescribe the drug during breastfeeding, the latter should be discontinued for the period of treatment.

Analogues

The active substance of Trichopolum is metronidazole, so drugs based on it can be analogues of the drug. These are:

  1. Metronidazole;
  2. Analog of Trichopolum - Orvagil;
  3. Metroseptol;
  4. Rosex;
  5. Analog of Trichopolum - Trichosept;
  6. Flagyl;
  7. Trichobrol;
  8. Analogue of Trichopolum - Klion;
  9. Batsimex;
  10. Deflamon.

Attention: the use of analogues must be agreed with the attending physician.

Prices

The price of Trichopolum is relatively small. It fluctuates in Russian pharmacies around 70-150 rubles. It is worth noting that Trichopolum, against the backdrop of expensive drugs, is an ideal remedy that combines inexpensive cost and quality. Numerous reviews from doctors speak about this on medical forums. You can find out what consumers think about Trihapol by reading reviews on the Internet.

Storage conditions

According to indications, Trichopolum is dispensed only as prescribed by a doctor. The medicine must be stored out of the reach of children, in a dry, ventilated and protected from light place, at room temperature up to 25°C.

The instructions for use position the drug "Trichopol" as an effective antimicrobial and antiproterozoic agent that is used for the treatment of bacterial infections. The medicine is well tolerated by patients and does not have serious side effects.

Composition and release form

It is produced in the form of oral and vaginal tablets (often called suppositories), as well as a solution for infusion in ampoules. The main active ingredient is metronidazole, on which the properties of the drug depend. The list of excipients depending on the form includes:

  • citric acid monohydrate;
  • crospovidone;
  • magnesium stearate;
  • povidone;
  • sodium chloride;
  • gelatin;
  • silicon dioxide and other components.

pharmachologic effect

Does Trichopolum help?

Indications for use of the drug are:

  • acute and chronic form of trichomoniasis;
  • vaginitis caused by the action of Trichomonas and other microbes;
  • stomach and intestinal ulcers (“Trichopol” is treated together with “Amoxicillin” and bismuth-containing drugs);
  • giardiasis;
  • liver abscesses caused by amoebas;
  • prevention of postoperative complications in gynecology, during appendicitis removal, colon surgery;
  • infectious pathologies caused by the action of anaerobic bacteria;
  • peritonitis;
  • inflammation of the ovaries;
  • endometritis;
  • pneumonia;
  • pleural empyema;
  • brain abscess;
  • suppuration of the liver and abdominal cavity;
  • meningitis;
  • skin infections.
  • inflammation of the fallopian tubes.

Instructions for use

Pills

The drug "Trichopol" for trichomonas infections is taken orally twice a day after meals in a volume of 250 g. Additionally, the insertion of suppositories into the vagina is required. Therapy is carried out for 10 days. For diseases of the reproductive system, both partners need to take the drug.

For peptic ulcers, you need to drink 0.25 g of the drug twice a day after meals. For bacterial vaginitis, the use of 1 g of the drug is prescribed; in the presence of anaerobic bacteria, the dosage is increased to 1.5 g. For patients with dysfunction of the renal parenchyma, the volume of the drug is reduced three times.

How to use Trichopolum suppositories

Instructions for use instruct vaginal tablets to be immersed in boiled water before use. For vaginitis and vaginosis, 1 suppository per day is prescribed, which is used together with tablets for 10 days. The medicine should not be used more than 2-3 times a year.

Application of the solution

The infusion is performed over 30 minutes, introducing 1 g of the drug. More than 4 g should not be used per day. When treating children under 12 years of age, the volume of medication is calculated based on body weight (7.5 mg of the drug should be per 1 kg).

Contraindications

Trichopolum is not prescribed for:

  • leukopenia;
  • lesions of the central nervous system;
  • liver failure;
  • epilepsy;
  • hypersensitivity to the active component;
  • when breastfeeding;
  • in the early stages of pregnancy;
  • children under 3 years old.

Side effects


Also, when using Trichopolum, nasal congestion, thrombophlebitis, gynecomastia, pustular rashes, fever, itching, and skin rash may occur.

Analogs and price

You can purchase the medicine in tablets for oral use for 90-100 rubles for 20 pieces. Trichopolum suppositories, the price of which is about 180-250 rubles for 10 vaginal tablets, can be purchased at the pharmacy. Analogues of the active ingredient are the drugs "Efloran", "", "".

Conditions of release and storage

In the pharmacy chain, vaginal tablets Trichopolum are dispensed with a doctor's prescription. Their independent use is not allowed, as this can lead to various complications and health consequences.

The shelf life of vaginal tablets Trichopolum is 3 years. They should be stored in the original original packaging, in a dark, dry place, out of reach of children, at an air temperature no higher than +25° C.

The tablets are small in size and have a white-yellowish tone. Shape: flat and round, with a dividing strip. When exposed to direct light, they acquire a rich yellow tint. One tablet of this medicine contains:

The medicine is produced in strips of 10 pieces. The box includes 2 plates, that is, 20 tablets. It is also produced in the form of suppositories, which are intended for vaginal use and solutions for intravenous injection. Each package of medicine contains instructions for use, which must be read carefully before starting therapy. Sold in pharmacies only upon presentation of a prescription.

The active ingredient of this medicine (Metronidazole), which is highly active in relation to:

  1. Gram-positive microorganism - Peptostreptococcus spp., Peptococcus spp., Clostridium spp., Eubacterium spp;
  2. Obligate anaerobes - Prevotella spp., Veillonella spp., Fusobacterium spp., (Prevotella disiens, Prevotella buccae, Prevotella bivia); Bacteroides spp. (including Bacteroides vulgates, Bacteroides thetaiotaomicron, Bacteroides ovatus, Bacteroides distasonis, Bacteroides fragilis.);
  3. Other microbes - Lamblia spp, Giardia intestinalis, Gardnerella vaginalis, Entamoeba histolytica, Trichomonas vaginalis.

The drug does not exhibit a bactericidal effect against some bacteria, viruses and fungi. With mixed flora (aerobes and anaerobes), metronidazole has synergistic effects with antibiotics that are effective against simple aerobes.

Metronidazole significantly increases the sensitivity of tumor formations to radiation, causing sensitization to ethanol, that is, it stimulates reparative processes.

When treated with this drug in parallel with amoxicillin, activity against Helicobacter pylori is observed, since amoxicillin suppresses the emergence of resistance to trichopolum (its active substance).

Drug interactions

Metronidazole, interacting with anticoagulants from the coumaron series, is doubly effective, but the dose in this case should be reduced by 2 times. Taking metronidazole may cause a negative reaction after taking ethanol. Negative neurological reactions may occur if the dosage interval with disulfiram is not observed. It must be at least 14 days.

Cimetidine enhances the concentration of metronidazole in the blood. This may cause side effects. On the contrary, phenobarbital and phenytoin accelerate the metabolism of the drug and remove it from the body faster. Trichopolum does not combine with vecuronium bromide. Sulfonamides help accelerate the destruction of microorganisms by metronidazole.

Pharmacokinetics

Metabolization

The active substance is metabolized in the liver in 30-60%, which occurs by hydroxylation. By oxidizing and binding to glucuronic (uronic) acid, the main metabolite also has antibacterial and antiprotozoal effects.

Distribution

Metronidazole is bound to plasma proteins in at least 20%. It penetrates into body fluids and tissues, including:

  • seminal fluid;
  • mother's milk;
  • vaginal secretion;
  • cavity abscesses;
  • amniotic fluid;
  • salivary compartment;
  • bile contents;
  • medullary tubules;
  • cerebrospinal fluid;
  • skin;
  • organs of the liver, kidneys, lungs.

It also passes through the placental barrier and the blood-brain barrier. In adults, Vd is 0.55 l/kg, and in infants from 0.54 to 0.81 l/kg.

Important! Trichopolum is not an antibiotic - it is a medicine with a wide spectrum of effects that has a destructive effect on all simple microbes, causing them to die.

Suction

After taking the medicine orally, the active substance leaves the gastrointestinal tract almost completely and as soon as possible. Its bioavailability is 80% and can be achieved in the blood 1-3 hours after administration. Eating food affects the rate of absorption of metronidazole into the blood, which occurs much more slowly.

Removal

If the liver performs its functions normally, the drug leaves the body after an average of 8 hours. 60-80% - by the kidneys, 6-15% - by the intestines, the remaining 20 percent comes out unchanged.

Pharmacokinetics in selected cases

If the liver is damaged by alcohol, metronidazole leaves the body on average after 18 hours. From the body of newborns who were born prematurely - at 28-30 weeks - after 75 hours; at 32-35 weeks - 35 hours, at 36-40 weeks - 25 hours. The active substance, as well as metabolites during hemodialysis, leave the blood quickly. In the case of peritoneal dialysis, they are released in a small dose.

Indications for use of Trichopolum

  1. Presence of adnexitis;
  2. Trichomoniasis;
  3. Bactericidal vaginosis;
  4. Giardiasis;
  5. Cystitis;
  6. Various infections.

Helps well in treating acne. The therapeutic effect is to destroy the DNA of the microbial cell with metronidazole. In addition to the listed diseases, Trichopolum is prescribed to people suffering from alcohol addiction. It causes an aversion to alcohol.

According to doctors, metronidazole is the best way to treat trichomoniasis. This is a disease of the human genitourinary organs caused by Trichomonas. In this case, take 1 tablet orally in the morning and in the evening before bed, and also use this medicine by vaginal administration, but it is better to use suppositories for this. The drug is also used for infections caused by aerobic bacteria: postoperative complications, skin infections, abscess of the lung, brain, liver disease, meningitis, inflammation and ulcerative pathologies of the gastrointestinal tract. What is treated with metronidazole is approximately clear. Now about how to take the medicine.

Methods of application

Trichopolum tablets, the instructions for use of which contain a lot of useful information regarding treatment, should be taken in appropriate doses.

For various diseases, the doctor prescribes a special medication regimen:

  • Trichomonas vaginitis - combine oral administration with 1 tablet per day vaginally. The course of treatment should not exceed 10 days;
  • Before surgical interventions: abdominal, obstetric and others, as well as as a prophylactic agent, adults take 4 tablets at a time for 2 days before the intervention, then 250 mg 3 times a day after meals. Children under such circumstances are prescribed 0.5 tablets 4 times a day;
  • Various infections - adolescents 12 years old and adults take 1-2 tablets 3 times a day with meals. For young children, a dose of 7.5 mg per 1 kg of lean body mass is calculated 3 times a day. The course of therapy for both children and adults is 7 days;
  • Giardiasis – 500 mg divided into two doses per day for 5-10 days. Children take half the dose;
  • Amebiasis – 3 tablets 3 times a day for 5-10 days. For children, the dose is calculated at 50 mg per 1 kg of child weight and is divided into 3 doses;
  1. When treating trichomonas vaginitis in women and trichomonas urethritis in men, both partners should take the drug. If after treatment signs of giardiasis appear, a stool test is performed a month later.
  2. You should not drink alcohol during treatment. In pediatrics, metronidazole is not compatible with amosicycline.

Important! It should be remembered that the doses and frequency of taking any medications should be prescribed strictly by a doctor.

Side effects

Side effects usually occur due to improper use of the drug, namely in overdoses, and manifest themselves differently in relation to the organs and systems of the body:

From the hematopoietic system:

  1. Pancytopenia is when there is a decrease in the blood (red blood cells, leukocytes, platelets and platelets.);
  2. Neutropenia is an increased susceptibility to bacteria and fungi, as a result of which immunity decreases and the body becomes less resistant to infections;
  3. Thrombocytopenia - a decrease in thrombotitis in the blood;
  4. Agranulocytosis - a sharp decrease in granulocytes in the blood;
  5. Leukopenia is a decrease in white blood cells.

From bones and muscles:

  • Myalgia is muscle pain due to cell hypertonicity.

Allergic reactions:

  1. Hives;
  2. Nasal congestion;
  3. Arthralgia – pain in the joints;
  4. Fever;
  5. Skin rashes;
  6. Exudative erythema multiforme is a disease of the mucous membranes and skin.

From the reproductive and urinary systems:

  • Pain inside the vagina;
  • Urine is reddish-brown in color;
  • Urinary incontinence;
  • Polyuria;
  • Cystitis is an inflammatory process occurring in the urinary system;
  • Dysuria is a disturbance or difficulty in urinating.

From the side of the central nervous system:

  1. Cramps are involuntary muscle contractions;
  2. Hallucinations are disturbances of perception;
  3. Unclear thinking;
  4. Weakness, sleep disturbance;
  5. Depression is a serious mental disorder;
  6. Irritability, severe excitability;
  7. Peripheral neuropathy – nerve disorders;
  8. Dizziness or just pain in the head;
  9. Impaired motor coordination - lack of ability to perform precise movements;
  10. Encephalopathy - in rare cases.

From the gastrointestinal tract:

  • Cholestatic hepatitis - damage to liver cells;
  • Jaundice is yellowing of the skin, a symptom of liver disease;
  • Pancreatitis is an inflammatory process in the pancreas;
  • Impaired liver function;
  • Dry mouth;
  • Glossitis - inflammation of the tongue;
  • Stomatitis is inflammation of the oral mucosa;
  • Unpleasant metallic taste in the mouth;
  • Diarrhea - stool instability;
  • Decreased or complete lack of appetite;
  • Impaired taste;
  • Constipation - stool disorders;
  • Intestinal colic - sharp paroxysmal pain in the intestines;
  • Anorexia - severe weight loss;
  • Epigastric pain - manifests itself in the upper or middle part of the abdomen;
  • Nausea;
  • Urge to vomit.

Men take Trichopolum for sexually transmitted infectious diseases and alcoholism. It also has a preventive antimicrobial effect.

Trichopolum is an antimicrobial drug that contains metronidazole. The medicine is available in two forms: tablets and solution. Trichopolum tablets are more often used for treatment, taken orally, the dosage is 250 or 500 mg.



The price ranges from 200 to 270 rubles. Trichopolum is mainly prescribed for:

  1. Infections of the urinary and reproductive system (for example, gonorrhea or trichomoniasis).
  2. Skin infections.
  3. Inflammation of the abdominal cavity.
  4. Respiratory tract infections.

Trichopolum is used for prophylactic purposes after operations for complications.

The course of treatment should not last more than ten days. Avoid alcohol during treatment. Take after meals with plenty of water or milk. At the first symptoms of side effects, stop taking the medication.

Application for men

Trichopolum is prescribed to men for the treatment of infections, diseases of the urinary and reproductive systems, such as gonorrhea, urethritis, balantidosis, etc. Men take this drug for stomach and intestinal ulcers, microflora pathologies, periodontal diseases, and amebiasis.

Side effects

  • disruption of the gastrointestinal tract;
  • dizziness, rarely convulsions, bad mood, foggy consciousness;
  • allergies - rash on the body, swelling of the face and neck. The reaction intensifies when drinking alcohol;
  • change (decrease) in the number of leukocytes in the blood;
  • nausea and vomiting;
  • diarrhea;
  • insomnia;
  • hearing loss.
  • for disorders of the nervous system;
  • liver and blood diseases;

Interaction of the drug with other drugs:

  • with antibiotics (for example, erythromycin or gentamicin), the effect of Trichopolum is enhanced;
  • with sleeping pills it decreases.

Worms can live asymptomatically in your body for years and their waste products will interfere with the functioning of your body and cause other diseases, the course of which often becomes chronic.

You are familiar with the following symptoms firsthand:

  • nausea;
  • gases and bloating;
  • frequent colds;
  • poor sleep;
  • weight problems;
  • excessive nervousness;
  • fatigue;
  • skin problems?


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