The drug "Hexicon" (candles): instructions for use, indications and side effects. Why is Hexicon prescribed? Instructions for medical use Hexicon suppositories instruction

• Latin name: Hexicon
• ATX code: D08AC02
• Active substance: Chlorhexidine bigluconate (Chlorhexidini bigluconas)
• Manufacturer: OAO Nizhpharm, Russian Federation

Compound

One suppository Hexicon includes 16 mg Chlorhexidini bigluconas

Part candles Hexicon D includes 8 mg Chlorhexidini bigluconas , as well as a polyethylene oxide base (polyethylene oxide 1500/Polyaethylenoxydum 1500, polyethylene oxide 400/Polyaethylenoxydum 400).

IN solution for external use contains 0.5 mg solution Chlorhexidini bigluconas with a concentration of 20%, purified water (Aqua purificata).

in one hundred grams gel contains 0.5 g Chlorhexidini bigluconas and auxiliary components: cremophor - RH 40 (Cremophor RH 40), poloxamer 407 (Poloxamerum 407), purified water (Aqua purificata).

One Hexicon vaginal tablet contains 16 mg Chlorhexidini bigluconas (as a solution Chlorhexidini bigluconas with a concentration of 20%) and auxiliary components: microcrystalline cellulose (Cellulosum microcrystallisatum), pregelatinized corn starch (Amylum maidis), low molecular weight povidone (Povidone), stearic acid (Acidum stearicum), lactose monohydrate (Lactose monohydrate).

Release form

The manufacturer produces the drug in the form of:

• vaginal suppositories 8 and 16 mg;
• solution;
• gel;
• vaginal tablets 16 mg.

pharmachologic effect

Hexicon belongs to the pharmacotherapeutic group of drugs antiseptic and disinfectant action . Interacting with structures microbial cell , it disrupts vital activity, inhibits development and provokes death pathogenic .

The use of various dosage forms of Hexicon in gynecological practice allows not only to successfully deal with pathogenic microorganisms , but also to carry out the prevention of infectious diseases transmitted by PP.

Pharmacodynamics and pharmacokinetics

Hexicon, which is part of the active ingredient, is a strong disinfectant, the sensitivity to which exhibits a wide range microorganisms , including including Gram (+) and Gram (-) bacteria , protozoa , herpesviruses .

Hexicon is effective against:

• gonococci (Neisseria gonorrhoeae);
• pale treponema (Treponema pallidum);
• chlamydia (Chlamydia spp.);
• gardnerell (Gardnerella vaginalis);
• ureaplasma (Ureaplasma spp.);
• bacteroid fragilis (Bacteroides fragilis);
• Trichomonas (Trichomonas vaginalis);
• herpesvirus type II (HSV-2).

Individual strains are characterized by weak sensitivity to the drug. pseudomonas (Pseudomonas spp.) and protea (Proteus spp.). Resistant to its effects are viruses , mushrooms , bacterial spores , acid resistant bacteria .

Thanks to the Hexicon chlorhexidine drug has a number of advantages over others antimicrobial And antiseptics . He:

• does not violate the natural microflora of the female genital tract and does not affect activity. lactobacilli ;
• does not cause addiction and resistance to its action in those sensitive to it microorganisms (even with repeated use);
• licensed for treatment pregnant and lactating women ;
• retains (albeit to a lesser extent) activity in the presence of spotting and pus.

The effectiveness of suppositories is also ensured by the features of their constituent polyethylene oxide 1500 (Polyaethylenoxydum 1500) and polyethylene oxide 400 (Polyaethylenoxydum 400). These substances provide a more uniform distribution of the active substance over the surface. mucous membrane and deeper penetration into tissues.

In addition, the polyethylene oxide base dehydrates pathogenic microorganisms and cleanses the mucosa from the products of their vital activity accumulating on it.

Hexicon vaginal tablets have been developed as an alternative to suppositories. For some women, they are somewhat more convenient than candles, since they do not increase the volume of secretions and, therefore, do not require the use of additional hygiene products.

Practically not absorbed from gastrointestinal tract , as well as through the skin and mucous membranes when applied topically. Systemic absorption when using Hexicon tablets intravaginally is extremely negligible.

In case of inadvertent ingestion of 0.3 g Cmax is reached after half an hour and is 0.206 µg / l.

The drug is eliminated from the body mainly with the contents of the intestine (90%), less than 1% is excreted by the kidneys.

Indications for use

Candles Hexicon - what are they from?

Candles Hexicon are indicated for prevention sexually transmitted infectious diseases caused by activity sensitive to the action of the drug microflora , for treatment inflammation of the genitals in women, to prevent the development of an inflammatory process and infection of the genital tract before childbirth, gynecological operations, abortion procedures, intrauterine examinations, etc.

Indications for the use of Hexicon D suppositories are children's gynecological diseases .

Indications for the use of solution, gel and vaginal tablets are the same as for suppositories.

Additional indications for the use of the solution

The solution is used as a disinfectant for processing festering wounds And infected burns . In gynecology, surgery and urology, it is used to treat skin infections And mucous .

Dentists prescribe rinses with Hexicon for aphthous stomatitis , gingivitis , inflammatory lesions of periodontal tissues and terminal parts of the respiratory tract .

Additional indications for the use of the gel

Gel Hexicon use for the treatment of inflammatory diseases in gynecology , dentistry And urology . In addition, they are treated with infected areas of the skin.

Contraindications

Contraindications to the appointment of Hexicon are hypersensitivity to its components.

Additional contraindication for the solution -.

Gel and suppositories are used with caution in the treatment of children. The optimal dosage form for a child is Hexicon D suppositories.

Side effects

The most common side effects of candles are, itching And burning into the vagina. These symptoms do not require specific treatment and disappear on their own after stopping the course of treatment.

Hexicon D vaginal suppositories provoke unwanted side effects in less than 0.1% of cases.

Undesirable reactions to the use of the solution are also extremely rare. As a rule, they are expressed in the form allergy symptoms And itching passing after the termination of the course of treatment.

For some, the Hexicon solution causes dry skin of the hands, sticky hands (usually no more than three to five minutes), photosensitivity . Rinses of the oral cavity with them lead to staining of tooth enamel, deposition of tartar, taste disturbances. Gel can also provoke similar phenomena.

Instructions for use Hexicon

Candles Hexicon: instructions for use

Candles are intended for intravaginal use.

For medicinal purposes, twice a day for 7-10 days, one suppository is administered intravaginally. If necessary, the course of treatment is repeated after 20 days.

For a warning sexually transmitted diseases it is recommended to enter one suppository no later than two hours after unprotected intercourse.

Instructions for the use of Hexicon D are similar to the instructions for the use of 16 mg suppositories.

Gel Hexicon: instructions for use

For treatment of inflammatory urological And gynecological diseases the gel should be applied to the affected surfaces twice a day. The duration of treatment can vary from 7 to 10 days.

Infectious dermatological diseases treat by thinly applying the gel to the affected surfaces two or three times a day. How long the treatment will be depends on the clinical situation.

In dental practice, the ointment is used in the form of applications with a multiplicity of 2-3 times a day. The duration of one procedure is from one to three minutes. The duration of the course is determined depending on the clinical situation.

Instructions for use of the solution

The solution is used externally and topically in the form of applications, irrigations and rinses. For one procedure, it is necessary to apply on the affected surface of the skin or mucous membranes from five to ten milliliters of the product with an exposure of one to three minutes 2 or 3 times a day (the solution can be applied on a swab or by irrigation).

For prevention infections , which are transmitted by PP, it is advisable to use Hexicon if the procedure is carried out no later than two hours after sexual contact.

Using a nozzle, the liquid contained in the vial is injected into urethra (both women and men) or vagina . Dose for injection into the urethra for men - from 2 to 3 ml, for women - 1 or 2 ml. In vagina injected from 5 to 10 ml of solution. The nozzle is delayed for 2-3 minutes.

Also, the solution should treat the genitals and the skin of the inner surfaces of the thighs and pubis. It is not recommended to urinate within two hours after the procedure.

At inflammation of the urethra (including complicated ) complex therapy is supposed, which is supplemented by injection for ten days once or twice a day into the urethra of a solution in a volume equal to 2-3 ml (it is recommended to carry out the procedure every other day).

At diseases of the oral cavity appoint rinsing with a solution of the drug. The frequency of procedures is 3-4 per day. The amount of solution required for one procedure is from 5 to 10 ml.

Instructions for use of vaginal tablets

Before use, the tablet is moistened with water and injected into vagina .Daily dose depending on the diagnosis is 1 or 2 tablets. Treatment is carried out within 7-10 days.

For infection prevention , which are transmitted by PP, the tablet, like suppositories, is recommended to be administered within two hours after unprotected intercourse.

Overdose

Since the drug is practically not absorbed from gastrointestinal tract and is not absorbed when applied topically through skin covering And mucous , the likelihood of an overdose of them is considered unlikely.

To date, there is no information on cases of overdose with Hexicon.

Interaction

The effectiveness of the drug is enhanced with simultaneous use with ethanol .

Hexicon should not be used with intravaginally administered preparations containing iodine.

Sanation external genitalia does not affect the efficacy and tolerability of suppositories, since they are applied intravaginally.

Pharmaceutical incompatible with anionic detergents (saponins, Sodium lauryl sulfate, Sodium carboxy methyl cellulose) and soap. Chlorhexidine is inactivated in the presence of soap, therefore, before using the drug, it is necessary to thoroughly wash off soap residues from the skin and mucous membranes.

It is allowed to combine Hexicon with preparations containing a cationic group.

Terms of sale

OTC

Storage conditions

In a dry place, at a temperature not higher than 25°C for tablets, solution, suppositories and not higher than 20°C for gel.

Best before date

special instructions

Hygiene procedures do not affect the efficacy and tolerability of vaginal tablets and suppositories, since the drug in these dosage forms is administered intravaginally.

When using the solution in patients with head and spinal cord injuries as well as in patients with perforation of the tympanic membrane should be avoided getting into the wound.

If the solution accidentally gets on mucous membranes of the eye , they are recommended to be rinsed quickly and very well with water.

Contact with bleaching agents containing in their composition on clothes that were previously in contact with drugs chlorhexidine , provokes the formation of brown spots on them.

An increase in the temperature of the solution causes an increase in bactericidal action . However, at temperatures exceeding 100°C, there is a partial decomposition of the drug.

How to enter candles?

To prevent leakage of the contents after the introduction of the suppository, the woman should lie on the bed, spreading her legs bent at the knee joints. The candle is inserted as deep as possible into vagina index finger (if possible to the depth of the finger).

If the suppository is not inserted deep enough, it may fall out after the woman gets up before it dissolves.

The principle of operation of Hexicon is similar to the principle of vaginal baths. A feature of these candles is that they are driven several times a day, as a result of which the amount of discharge increases significantly. Given this, during the treatment period, daily pads should be changed as often as possible.

Another feature of suppositories is that there is no need to prescribe additional sanitation before their introduction. vagina or douching, which makes their use more convenient than other vaginal suppositories.

An important recommendation for the period of treatment is the exclusion of sexual intercourse. If therapy is carried out against the background of a regular sexual life, then a positive result will not be achieved. There remains a risk of re-infection and as a result, it may be necessary to prescribe drugs not only local, but also systemic.

The use of Hexicon during menstruation

Quite often, questions arise whether it is possible to use suppositories during menstruation and whether it is allowed to be treated with vaginal tablets during menstruation.

The instructions for Hexicon indicate that the use of suppositories and tablets during menstruation is permissible. This is due to the fact that the active substance of the drug retains (albeit to a lesser extent) pharmacological properties in the presence of pus, spotting and other biological fluids.

Hexicon's analogs

Analogues in composition for Hexicon in the form of a solution and gel are drugs Amident (solution for topical application) and Chlorhexidine in the form of an alcohol solution, solution, concentrate for the preparation of a solution, spray.

According to the mechanism of action, they are closest (cream), (cream), Lavasept (concentrate for preparing a solution), (solution).

Candles and tablets Hexicon have a similar composition with, respectively, candles and tablets Chlorhexidine . Similar drugs according to the mechanism of action for suppositories are (suppositories), Hyposol (aerosol), Yodovidone (candles), (candles), (cream, capsules, tablets, suppositories), vaginal suppositories with trichomonacid, vaginal suppositories with eucalimine, Trichomonacid (tablets), (powder, tablets, granules for suspension), Vagiflor (capsules), (suppositories), (cream), (capsules).

Hexicon during pregnancy

All dosage forms manufactured under the Hexicon brand, with the exception of vaginal tablets, are allowed to be prescribed during and during the period. In the instructions for candles Hexicon at pregnancy And lactation it is indicated that this remedy is considered not only effective, but also safe for both mother and child.

As for vaginal tablets, their use is possible if the benefit to the mother outweighs the risk to the fetus.

Candles Hexicon at pregnancy are one of the most commonly prescribed drugs for the treatment and prevention gynecological diseases . The safety of the drug is ensured by its local effect and is confirmed by many years of experience in use.

Acting locally, its active substance practically does not enter the systemic circulation and thus does not pose a threat to the normal development of the child. Therefore, candles are allowed to be used at all stages of pregnancy.

Hexicon effectively affects pathogenic , which are the cause of women's diseases, but at the same time does not provoke any violations of their own cervical erosion . It is advisable to prescribe them in cases where the cause of ulceration is the activity of pathogens transmitted by PP, or inflammatory “female” pathologies.

During pregnancy Hexicon is most often prescribed for bacterial vaginosis when in vagina dominated pathogenic bacteria , and the quantity lactic acid bacteria (lactobacilli) - reduced or these bacteria are completely absent.

Decrease in quantity lactic acid bacteria a pregnant woman in the background bacterial vaginosis may lead to the development vulvovaginal candidiasis (or, in other words, ).

As practice shows, every year cases of combination And is getting bigger. For this reason, it is widely believed that Hexicon candles are effective in thrush .

Candles Hexicon from thrush

Provokes development vulvovaginal candidiasis yeast-like fungus of the genus Candida who, like many viruses , bacterial spores And acid-fast bacteria , immune to the effects chlorhexidine .

So why are these candles prescribed for pregnancy from thrush ? It's all about the reason thrush is uncontrolled growth Candida fungus colonies , which can be provoked, among other things, by the activity of infectious pathogens - gonococci , Trichomonas and others bacteria and protozoa .

In such cases when infection wears mixed, fungal-bacterial character , the expediency of using Hexicon is due to its ability to effectively remove signs of inflammation, reduce tissue swelling and significantly reduce the severity of pain.

To combat the over-proliferated fungus , which is the direct source of the disease, use antimycotic drugs in the form of gels, creams and vaginal tablets (for example, or).

It is important to remember that self-medication - especially during pregnancy - unacceptable, and Hexicon from thrush prescribed only on the basis of a medical examination and the delivery of all necessary tests.

Thus, Hexicon candles are an effective and safe antibacterial agent for local use, but for treatment candidiasis it is recommended to choose drugs that can actively suppress the main culprit of the disease.

A prerequisite for successful treatment is compliance with the requirements of personal hygiene and - in some cases - the preparation of a special dietary menu that involves limiting the amount of food with a high content of carbohydrates in it, and introducing a sufficient amount of fermented milk products into the diet.

Many women face problems such as sexually transmitted diseases (STDs). In most cases, they do not pose a threat to a woman's health if warned in time. The female body copes with pathogenic bacteria on its own, but sometimes it needs help. From what candles "Geksikon"? It is a topical antiseptic that is used to protect against genital infections.

Description

Vaginal suppositories "Hexicon" is a medical preparation used in gynecology to eliminate STDs. "Hexicon" belongs to the group of antiseptic, antibacterial agents, fights against sexually transmitted diseases. Available in the form of suppositories or suppositories, it is easy to use. after "Hexicon" they are rare, since the remedy does not violate the microflora of the vagina and does not adversely affect reproductive function.

Assign "Hexicon" as an antiseptic before abortion, childbirth, before surgery in the field of gynecology, before examining the uterine cavity, when establishing an intrauterine device. The main advantage of suppositories is efficiency. The drug acts quickly and is able to suppress the pathogen before it penetrates the vaginal mucosa during dangerous sexual intercourse.

Indications for use

Who is prescribed the drug "Hexicon"? The main indications for the use of suppositories are venereal infectious diseases, for example, syphilis, trichomoniasis, gonorrhea, chlamydia; different types of vaginitis, cervitis, bacterial colpitis.

Bloody discharge after Hexicon is observed in women who use this drug as prescribed by a gynecologist. Suppositories can provoke the appearance of minor secretions with an admixture of blood due to their composition. However, this is not considered the norm. When injected into the vagina, suppositories dissolve under the influence of body temperature, providing a therapeutic effect. Excess drug comes out.

Normally, the female secret after candles should be viscous, transparent, colorless, odorless. The instructions for use do not say that one of the side effects may be spotting, so after they occur, you should stop using Hexicon and consult a doctor.

After "Hexicon", if they are insignificant, they indicate mechanical damage to the vessels or mucous membranes due to inaccurate administration of suppositories. Blood also appears as a result of placental abruption if a pregnant woman uses suppositories. If spotting appears, but pain and discomfort are absent, it is important not to hesitate to visit a gynecologist.

Instruction

"Hexicon", in addition to the main indications for use, is used as a contraceptive and for the prevention of inflammatory processes. The composition of suppositories includes the main active substance - chlorhexidine bigluconate, as well as additional components - purified water and polyethylene oxide.

Bloody discharge after Hexicon is not the norm. The drug may cause brown secretion. Mucus with brown streaks results from the release of gore. This sometimes indicates a frozen pregnancy and is accompanied by pulling pains in the lower abdomen. White, yellow, green discharge against the background of the use of suppositories indicates a severe infection that requires more serious treatment.

Candles are inserted directly into the vagina. For the treatment of infectious and inflammatory diseases, one suppository is prescribed once or twice a day. It is best to use suppositories at night, so the therapeutic effect will not bring discomfort and will be as effective as possible. The course of treatment is seven to ten days.

In order to prevent "Hexicon" is recommended to be administered after unprotected intercourse. It is advisable to use candles after the end of menstruation, but not during. The peculiarity of the drug is that it is prescribed during pregnancy, it does not adversely affect the fetus. During use, you must fully rely on the instructions "Hexicon". The price of the drug is quite democratic.

Side effects

Bloody discharge after Hexicon is not a side effect, since this information is not in the instructions for use. The main adverse reactions after suppositories include:

• feeling of dryness in the vagina;
• itching and burning;
• mucosal redness.

The active substance "Hexicon" can cause quite rare side effects in hypersensitive women. These include dry skin, taste disturbance, staining of tooth enamel. The drug acts locally, and the active substance is practically not absorbed into the blood. This means that unwanted symptoms are minimized.

For the duration of treatment, it is better to exclude sexual intercourse and wait for a complete recovery in order to avoid side effects. "Hexicon" is a domestic drug that has established itself as an effective remedy against genital infections. It is produced not only in the form of candles, but also solutions.

Contraindications

Does "Hexicon" cause side effects, have already been found out, but who is this drug contraindicated in? You can not be treated with "Hexicon" for women who are highly sensitive to the composition of suppositories. If suppositories cause discomfort after use, including discharge with blood, therapy should be discontinued and a doctor should be consulted. For the period of treatment, it is not recommended to wash with soap or other means. In contact with the active substance, they cause burning and itching.

If "Hexicon" is used by a healthy woman, the components do not violate the natural microflora and do not adversely affect beneficial microorganisms. It is not recommended to take "Hexicon" for dermatitis, allergic reactions.

If you exceed the dosage, the drug increases the side effects. During pregnancy, including in the later stages, suppositories are not contraindicated. They are prescribed by a doctor to stabilize the microflora.

Analogues

From what candles "Geksikon"? Vaginal suppositories are used to combat genital infections. Candles have inexpensive structural analogues that have an identical chemical composition, active substance and spectrum of action. The analogues of "Hexicon" include "Citeal", "Depantol", "Hibiscrab", "Catejel C", "Plivasept", "Chlorhexidine".

Price

What is the price of "Geksikon"? The instructions for use tell you how to use candles correctly. They are inexpensive. The price of this domestic drug is 289 rubles per pack of 10 pieces. You can buy suppositories in any pharmacy chain.

Normally, the protection of the vaginal mucosa from infections is provided by certain immune and humoral factors. An important role is played by the composition of the microflora, represented by more than 20 species of various microorganisms. Violation of these defense mechanisms leads to the activation of opportunistic microflora and the occurrence of inflammatory changes.

Causes of inflammation of the "female organs"

Vulvovaginitis and vaginitis are most often caused by the following types of microorganisms:

• staphylococci;
• streptococci;
• enterococci;
• corynebacteria;
• coli;

Basically, the pathology is caused by the bacteria that are the inhabitants of the intestine - enterobacteria, coliform microorganisms. Less commonly, vulvovaginitis is provoked by gram-positive cocci, Pseudomonas aeruginosa, corynebacteria.

Recently, it has been established that often inflammatory changes in the vagina are provoked by two or three, and sometimes by a large number of pathogens. Vaginitis of mixed etiology is diagnosed in more than a third of patients.

Not so rare, along with opportunistic microflora, sexually transmitted infections (STIs) are detected. Most often, smears in patients with vulvovaginitis reveal chlamydia, trichomonas, ureaplasma, gonococcal infection. Inflammatory diseases of the vagina and external genital organs caused by mixed infection are especially difficult. Under certain conditions, they can lead to complications in the form of the spread of infection to other parts of the woman's reproductive system. In addition, diseases of mixed etiology are especially prone to chronicity of the process with the occurrence of frequent relapses.

Benefits of topical preparations

That is why the treatment of such pathologies requires the appointment of broad-spectrum antimicrobial agents. However, most of the antibacterial pharmaceuticals are not suitable for the treatment of chronic forms of the disease, moreover, they often cause a violation of the vaginal microflora. In addition, most pathogens eventually become resistant to some antibiotics. This is especially true for systemic drugs administered orally or parenterally.

Optimal for the treatment of vaginitis in women are topical preparations. The main advantages of using them are:

• lack of a large number of side effects;
• simplicity, ease of use;
• minimum contraindications.

All these requirements are fully met by the drug "Hexicon", produced in the form of suppositories. It is effective in inflammatory diseases of the genital organs and at the same time is safe for the woman's body.

What is this medicine and what suppositories treat

Do hexicon candles help and how to insert them correctly? "Hexicon" is a drug that has antimicrobial and antiprotozoal activity. It can be used both for the treatment and for the prevention of infections of the vagina and external genital organs. "Gexosept" in candles can only be used topically. How many days to put candles? See instructions or follow your doctor's prescription.

The main active ingredient of this pharmaceutical preparation is chlorhexidine bigluconate, a substance with a strong antimicrobial effect. One candle "Hexicon" contains 0.016 g of chlorhexidine. Additionally, the composition includes a filler (macrogol), which dissolves under the action of heat and ensures uniform distribution of the drug.

In the pharmacy network, you can also find the drug "Hexicon D", which contains only 0.008 g of chlorhexidine. It is intended for the treatment of pediatric patients and girls who are not sexually active.

The spectrum of antimicrobial activity of "Hexicon" is quite extensive. It is effective against the following pathogens:

• pale treponema;
• chlamydia;
• ureaplasma;
• gonococcus;
• gardnerella;
• bacteroids;
• trichomonas;
• herpes simplex virus.

The mechanism of action of chlorhexidine is the formation of its active forms in the lumen of the vagina. The medicinal substance interacts with the membranes of bacteria and leads to disruption of the transport of potassium and phosphorus ions and the death of bacteria.

This process is also facilitated by the filler included in the drug. It actively adsorbs secretions and potentiates the antimicrobial properties of chlorhexidine. Therefore, the drug also works well in the presence of pus or blood. It is allowed to use "Hexicon" during menstruation, moreover, if treatment is started earlier, it is not recommended to stop it.

After introduction into the vagina, the drug binds well to the structures of the vaginal mucosa. However, it is practically not absorbed into the systemic circulation. In experiments, it was found that even with accidental ingestion of chlorhexidine, only a very small amount of it is absorbed into the blood.

"Hexicon" has low toxicity and can be used in women with different somatic status, as well as in pregnant women. Also, a great advantage of the drug is the absence of a negative effect on beneficial lactobacteria and bifidobacteria. After treatment with this drug, there is no violation of the vaginal microflora, which does not require additional administration of probiotics.

What diseases are prescribed

The main indications for the use of "Hexicon" are as follows:

• vaginosis with gardnerellosis;
• vaginitis;
• colpitis;
• vulvitis, vulvovaginitis and associated cystitis;
• with erosion of the cervix in complex therapy.

Also, the drug is actively used for preventive purposes. Assign "Hexicon" for:

• prevention of STIs after unprotected intercourse;
• before gynecological operations;
• with the introduction of an intrauterine device;
• after diathermocoagulation for cervical erosion;
• before childbirth with elevated leukocytes in a smear;
• with a pessary installed;
• after operations on the genitals.

Reviews of vaginal suppositories "Hexicon" indicate its good effectiveness precisely with inflammation of the vaginal mucosa and cervix. The drug can be included in combination regimens along with other drugs.

Candles "Hexicon": instructions for use

Suppositories "Hexicon" are used only vaginally. It is not recommended to use suppositories rectally or as an ointment.

• The introduction of the drug. Before their introduction, it is necessary to carry out a toilet of the genital organs. After that, you need to carefully remove the suppository from the package; for better administration, it can be moistened with water. A suppository with chlorhexidine is injected deep into the vagina.
• course treatment. According to the official instructions, for medicinal purposes, candles should be used twice a day, in the morning and in the evening. Usually the duration of therapy does not exceed ten days.
• Application in children. For the treatment of children, you can also use Hexicon candles with a dosage of 0.016 g. Before the introduction, the candle is cut lengthwise into two parts and then torpedo-shaped with your hands.
• For prevention. If the medicine is used for prophylactic purposes after an accidental sexual intercourse, then the dosage regimen is somewhat different. In this case, only one suppository is administered over the next two hours, but not later. Combine "Hexicon" and sexual intercourse should be only in some cases, it will be much safer to use barrier methods of contraception (condom).

After the introduction of the candle, there may be a small transparent discharge caused by its dissolution. Purulent or bloody discharge after Hexicon indicates the presence of gynecological pathology, and is in no way associated with the use of this medication.

Side effects and contraindications

According to doctors, the drug is very well tolerated. Occasionally, local side effects may occur:

• burning sensation in the vagina;
• allergic manifestations in the form of swelling, redness, rash.

A contraindication to the use of the drug is only individual intolerance to chlorhexidine or filler. Also, you should not use "Hexicon" simultaneously with cosmetic preparations containing detergents. This is true in the case of intravaginal use of such agents.

Carrying out hygiene of the external genitalia does not affect the effectiveness of Hexicon. For the entire period of use of the drug, not a single case of its overdose was registered.

Acquisition and analogues

You can buy "Hexicon" candles in any pharmacy chain. Given that they are domestically produced, their cost is low. A pack of ten candles will cost 260-280 rubles (data for October 2017).

The pharmacist can also offer analogues:

• "Chlorhexidine";
• "Depantol".

Suppositories "Chlorhekisdin", as well as "Hexicon", contain chlorhexidine bigluconate. The composition of suppositories "Depantol", in addition to chlorhexidine, also includes dexpanthenol, which has a regenerating effect on the vaginal mucosa.

The long-term use of "Hexicon" in gynecology has made it possible to study well all its positive aspects. Clinical studies have proven its safety and efficacy in inflammatory diseases of the female genital organs. Given the lack of systemic action, it can be used even during pregnancy or lactation. An important advantage of this medication is the absence of a negative effect on the microflora of the vagina. Unlike tablets, Hexicon suppositories do not have a harmful effect on the body and act exclusively locally. Therefore, they can be used not only for therapeutic, but also for preventive purposes.

Preparation: HEKSIKON®
The active substance of the drug: chlorhexidine
ATX encoding: D08AC02
KFG: Antiseptic for external and topical use
Registration number: LS-002718
Date of registration: 29.12.06
The owner of the reg. Award: NIZHFARM OJSC (Russia)

Release form Hexicon, drug packaging and composition.

Gel for local and external use 0.5% colorless, transparent.
Gel for local and external use 0.5%
1 g
chlorhexidine bigluconate
5 mg

Excipients: poloxamer 407, Cremophor RH-40 (polyoxyl 40 hydrogenated castor oil), purified water.

15 g - aluminum tubes (1) - packs of cardboard.
20 g - aluminum tubes (1) - packs of cardboard.
30 g - aluminum tubes (1) - packs of cardboard.

Solution for external use 0.05% colorless, transparent or slightly opalescent, odorless.
Solution for external use 0.05%
100 ml
chlorhexidine bigluconate (20% solution)
0.25 ml

Excipients: purified water.

50 ml - polyethylene bottles (1) with a polymeric nozzle - packs of cardboard.
100 ml - polyethylene bottles (1) with a polymeric nozzle - packs of cardboard.

The description of the drug is based on the officially approved instructions for use.

Pharmacological action Hexicon

Antiseptic drug for external and topical use.

Active against gram-positive and gram-negative bacteria - Treponema spp., Chlamydia spp., Ureaplasma spp., Neisseria gonorrhoeae, Gardnerella vaginalis, Bacteroides fragilis; protozoa - Trichomonas spp.; viruses - Herpes simplex type 2.

The gel, when applied to the skin and mucous membranes, has a bactericidal effect.

Retains activity (albeit somewhat reduced) in the presence of blood, pus.

Pharmacokinetics of the drug.

Practically not absorbed from the gastrointestinal tract. After accidental ingestion of 300 mg Cmax is reached after 30 minutes and is 0.206 μg / l. It is excreted mainly with feces (90%), less than 1% is excreted in the urine.

Indications for use:

Prevention of sexually transmitted infections (including gonorrhea, syphilis, trichomoniasis, chlamydia, ureaplasmosis, genital herpes);

Treatment of urethritis and urethroprostatitis (as part of complex therapy);

Disinfection of purulent wounds, infected burn surfaces;

Treatment of infections of the skin and mucous membranes (in surgery, obstetrics and gynecology, urology);

Treatment of infections of the skin and mucous membranes (in surgery, obstetrics and gynecology, urology),

In dentistry for rinsing and irrigation with gingivitis, stomatitis, aphthae, periodontitis, alveolitis.

In gynecology: treatment of vulvovaginitis;

In urology: treatment of balanitis, balanoposthitis;

In dentistry: treatment of gingivitis, stomatitis, aft, periodontitis, alveolitis;

In dermatology: treatment of skin infections (including pyoderma, impetigo, paronychia, panaritium, diaper rash).

Dosage and method of application of the drug.

Hexicon solution for external use

For the prevention of sexually transmitted infections, the drug should be used no later than 2 hours after sexual intercourse. The contents of the vial using a nozzle should be administered to men into the urethra at a dose of 2-3 ml, to women into the urethra - 1-2 ml and into the vagina - 5-10 ml, and hold for 2-3 minutes. Treat the skin of the inner surfaces of the thighs, pubis, genitals with a solution. After the procedure, the patient should not urinate for 2 hours.

Treatment of urethritis and urethroprostatitis is carried out by injecting 2-3 ml of Hexicon solution into the urethra 1-2 times / day, the course of treatment is 10 days. Procedures are prescribed every other day.

For lesions of the skin and mucous membranes, the Hexicon solution is used in the form of irrigations, rinses and applications (with a swab) - 5-10 ml of the solution is applied to the affected surface of the skin or mucous membranes with an exposure of 1-3 minutes 2-3 times / day.

Hexicon gel for local and external use

For the treatment of vulvovaginitis, balanitis, balanoposthitis, the gel should be applied to the affected surfaces 2 times / day for 7-10 days.

For the treatment of skin infections, the gel should be applied in a thin layer to the affected areas 2-3 times / day. The duration of the course of treatment depends on the clinical picture.

For the treatment of gingivitis, stomatitis, aphthae, periodontitis and alveolitis, the gel should be applied in the form of applications for 1-3 minutes 2-3 times / day. The duration of the course of treatment depends on the clinical picture.

Side effects of Hexicon:

With intravaginal use: allergic reactions, itching are possible, passing after the drug is discontinued.

For external and local use: allergic reactions, itching, dry skin, dermatitis, stickiness of the skin of the hands (within 3-5 minutes), photosensitivity; in the treatment of gingivitis - staining of tooth enamel, deposition of tartar, taste disturbance.

Contraindications to the drug:

Dermatitis;

Allergic reactions.

Hypersensitivity to the components of the drug.

The drug should be used with caution in children.

Use during pregnancy and lactation.

The drug Hexicon in the form of a solution for local and external use is not contraindicated for use during pregnancy and lactation.

Special instructions for the use of Hexicon.

When applied externally and locally, the drug should be avoided inside the wound in patients with open traumatic brain injury, spinal cord injuries, perforation of the eardrum.

If the solution comes into contact with the mucous membranes of the eyes, they should be rinsed quickly and thoroughly with water.

Exposure of hypochlorite bleaches to fabrics that have previously been in contact with preparations containing chlorhexidine may contribute to the appearance of brown spots on them.

The bactericidal effect increases with increasing temperature. At temperatures above 100°C, the preparation partially decomposes.

Drug overdose:

Currently, cases of overdose of the drug Hexicon have not been reported.

Interaction of Hexicon with other drugs.

Hexicon is incompatible with detergents containing an anionic group (including saponins, sodium lauryl sulfate, sodium carboxymethylcellulose) and soaps. The presence of soap can inactivate chlorhexidine, so soap residue must be thoroughly washed off before using the drug.

Ethanol enhances the effectiveness of the drug.

Conditions of sale in pharmacies.

The drug is approved for use as a means of OTC.

Terms of the storage conditions of the drug Hexicon.

The solution for external use should be stored out of the reach of children, protected from light, at a temperature not exceeding 25°C. Shelf life - 2 years.

Gel for local and external use should be stored out of the reach of children, protected from light at a temperature not exceeding 20 ° C. Shelf life - 2 years.

Content

Gel, solution, tablets or suppositories Hexicon are prescribed by a gynecologist for the treatment of inflammation of the genital organs in women. All forms of release of the drug belong to the category of broad-spectrum antiseptics. They are used for topical treatment of sexually transmitted infections, as well as some childhood diseases in gynecology. The indication for use is the preventive measures of these pathologies, especially before childbirth or operations.

Instructions for use Hexicon

The drug is based on a substance that has activity against gram-negative and gram-positive forms of bacteria. The drug has established itself as an excellent antiseptic against infections of the genital tract. The effectiveness of the active substance is somewhat reduced in the presence of pus or blood. The peculiarity of the drug is that it does not affect lactobacilli, which make up the normal microflora of the vagina.

Composition and form of release

Each release form contains the antiseptic chlorhexidine bigluconate as an active ingredient. Only the concentration of this component differs. Its presence is due to the properties of the antiseptic drug. The table shows the composition of the drug more clearly:

Pharmacodynamics and pharmacokinetics

Chlorhexidine, which is the basis of all forms of release of the drug, exhibits a strong disinfecting effect. A wide range of microorganisms is sensitive to it: herpesviruses, different types of bacteria, protozoa. Their list includes:

• fragilis bacteria;
• gonococci;
• ureaplasma;
• Trichomonas;
• chlamydia;
• pale treponema;
• gardnerella;
• herpes virus type 2.

Some strains of Pseudomonas and Proteus are less sensitive to chlorhexidine, and bacterial spores, viruses, fungi, and acid-resistant bacteria are completely resistant. The active substance is practically not absorbed from the digestive tract, as well as through the skin when applied topically. When administered intravaginally, systemic absorption is negligible. If you accidentally swallow a tablet, then its half-life will be 0.206 μg / l. The substance is excreted with feces from the intestines. The kidneys excrete less than 1% chlorhexidine.

What does Hexicon treat?

Suppositories and solution are used to treat and prevent infections that are sexually transmitted and develop after exposure to drug-sensitive microflora. Additionally, the list of indications for use includes:

• inflammation of the genital organs, vaginal mucosa, uterus and cervix;
• prevention of inflammatory processes before childbirth, abortion procedure and gynecological operations;
• treatment of infected burns and purulent wounds;
• infections of the skin and mucous membranes;
• aphthous stomatitis;
• gingivitis;
• inflammatory lesions of periodontal tissues.

How to take Hexicon

The release forms of this antiseptic differ in instructions for use. Suppositories and vaginal tablets are indicated for insertion directly into the vagina. The gel and solution can be used topically for local skin lesions. The course of treatment varies depending on the disease that requires treatment. Men can also use this medication, but only in the form of a gel or solution.

Candles Hexicon

This release form is intended for intravaginal use. For 7-10 days, you need to enter 1 suppository daily. If necessary, resort to a second course, but not earlier than 20 days after the end of the first therapy. To prevent the development of sexually transmitted diseases, the introduction of a vaginal suppository is indicated no later than 2 hours after intercourse without a condom. The scheme for using Hexicon D candles is similar.

Vaginal suppositories are very important to enter correctly so that the contents do not leak out of the vagina. To do this, a woman needs:

• lie on the bed, bend your legs and spread apart;
• insert the suppository into the vagina with the index finger to its depth;
• lie down for another 5-7 minutes, so that after taking a vertical position, the candle does not fall out.

According to the instructions for use, treatment with vaginal tablets or suppositories can also be carried out during menstruation. Although the active ingredient slightly reduces its effectiveness in the presence of pus, spotting or other biological fluids, therapy still brings a positive result than in its absence.

Hexicon tablets

Depending on the diagnosis, the daily dosage of the drug may be 1 or 2 tablets. Before the procedure, it must be moistened with water, and then inserted into the vagina. It is better to do this in a prone position. In order to prevent sexually transmitted infections, the administration of 1 tablet is indicated within 2 hours after unprotected intercourse.

Solution

The solution has a wider range of applications. It is used for irrigation, rinsing and local applications. For one procedure, about 5-10 ml of solution is needed, which is applied to the affected skin or vaginal mucosa. The focus can simply be irrigated with a liquid, or you can first moisten a swab in it, which is then applied to the sore spot. The procedure is repeated 2-3 times during the day. Other solution treatment options:

1. For diseases of the oral cavity. Showing 3-4 rinses per day 5-10 ml of solution.
2. For the prevention of sexual infections. Using a nozzle, the solution is injected into the vagina no later than 2 hours after unprotected intercourse. The dosage is 5-10 ml. The nozzle of the vial is held inside for 2-3 minutes. The solution needs to treat the skin on the inner thighs and genitals. Urination is prohibited for about 2 hours after the procedure.

Hexicon gel

This form of release is used externally for application to the mucous membranes or skin. For each disease there is a specific treatment regimen:

1. Inflammatory gynecological diseases. A thin layer of the gel is applied to the affected areas 2 times a day. The course of therapy can vary from 7 to 10 days.
2. Dermatological infections. Hexicon ointment is applied to the lesions 2-3 times a day. The duration of the procedures depends on the disease.
3. Dental diseases. The gel is used for 2-3 applications per day. One procedure lasts 1-3 minutes. It is necessary to continue treatment depending on the clinical situation.

special instructions

Hygiene procedures do not affect the effectiveness of therapy with suppositories or vaginal tablets. It is important to avoid getting the solution inside the wound in patients with trauma to the brain and spinal cord or perforation of the tympanic membrane. In case of accidental contact with the mucous membrane of the eye, immediate rinsing is required. At the time of treatment, it is recommended to exclude sexual intercourse. Regular sex life reduces the effectiveness of therapy. The result may be re-infection, which will require the use of not only local drugs, but also systemic ones.

During pregnancy

Each dosage form of antiseptic is approved for use during pregnancy and lactation. It is not only effective during this period, but also completely safe for both the mother and the fetus. The exception is vaginal tablets. They are used only when the expected benefit outweighs the potential harm. In the 1st and 2nd trimester of pregnancy, indications for use are:

• ureaplasmos;
• gonorrhea;
• chlamydia;
• trichomoniasis;
• genital herpes;
• exocervicitis;
• bacterial vaginosis;
• colpitis;
• vaginitis.

Although the drug is ineffective against Candida fungi, it is still prescribed for the treatment of thrush in pregnant women. The reason is that more often a fungal infection during this period in women is provoked by gonococci, Trichomonas and other bacteria. With a mixed fungal-bacterial nature of thrush, Hexicon is able to relieve signs of inflammation, reduce swelling and significantly reduce the severity of signs of the disease.

In childhood

For the treatment of the above infectious diseases in childhood, it is recommended to use Hexicon D. These suppositories are approved for the treatment of gynecological pathologies in children, including:

• genital herpes;
• trichomoniasis;
• vaginitis;
• syphilis.

Hexicon for men

Some inflammatory diseases in men are also treated with Hexicon. The scheme of application of different forms of release of the drug:

1. Gel. In the treatment of urological diseases, it is applied to the lesions twice a day for 7-10 days.
2. Solution. In order to prevent sexually transmitted infections, the liquid is injected into the urethra in an amount of 2-3 ml. The nozzle should be held for 2-3 minutes. In case of inflammation of the urethra, including complicated by prostatitis, for 10 days, 1-2 times a day, the solution is injected into the urethra. The procedure is carried out with a break of 1 day.

drug interaction

If you simultaneously use ethanol, then the effectiveness of the drug will increase. It is not recommended to be treated with Hexicon in conjunction with agents containing iodine. Other features of the interaction of this medication with other drugs:

• since suppositories are administered intravaginally, their tolerability and effectiveness are not affected by the sanitation of the external genital organs;
• incompatible with anionic detergents and soap, in the presence of which chlorhexidine is inactivated;
• approved for use with drugs containing a cationic group.

Side effects

The most common reactions to the use of suppositories is a local allergic reaction in the form of burning and itching in the vagina. When these symptoms appear, there is no need for specific treatment. They pass on their own after the end of the course of therapy. Very rarely, adverse reactions occur after using the solution. It could be allergies and itching. Judging by the reviews of patients, other undesirable reactions may occur:

• dermatitis;
• dry skin of the hands;
• stickiness of hands;
• photosensitivity;
• deposition of tartar;
• staining of tooth enamel;
• taste disorder.

Overdose

Due to the fact that the drug is not absorbed from the gastrointestinal tract and is not absorbed through the skin when applied topically, the risk of overdose is minimized. To date, there is no data on the condition that occurs when the dose of the drug is exceeded. Perhaps only an increase in side effects, the symptoms of which disappear on their own.

Contraindications

The main contraindication to the use of all forms of release of Hexicon is hypersensitivity and individual intolerance to the components in the composition. The solution can not be used in case of dermatitis. For the treatment of children, Hexicon D suppositories are optimal. Gel and suppositories are used with great care only as directed by a doctor.

Terms of sale and storage

Any form of release of the drug can be ordered or bought without a prescription from a doctor. The storage place should be dry, and the temperature in it should not exceed 25 degrees for the solution, tablets and suppositories and 20 degrees for the gel.

Hexicon analogue

Complete analogues of the drug are Chlorhexidine solution and Amident. If we compare the mechanisms of action, then Depantol, Bepanten, Tsiteal, Lavasept are closer. The list of analogues can include the following drugs:

• Iodoxide;
• Trichomonacid;
• Dafnedgin;
• Lactoginal;
• McMiror;
• Betadine;
• Vagiflor;
• Yodovidone;
• Hyposol;
• Furazolidone.

Hexicon price

If you study the catalogs of medicines in several online pharmacies, you can see different prices for Hexicon. This is due to the large number of manufacturers and formulations of the drug. Approximate prices are described in the table: