Spray "Yox": instructions for use for children. Yox is a broad-spectrum antiseptic antimicrobial drug

ARVI, tonsillitis, pharyngitis are quite common diseases. In the first days, we don’t even pay attention to the sore throat and slight sore throat. But in vain! Perhaps, if we take measures for the first time, the disease will not develop in full force. This means that there will be much fewer complications.

One of the drugs that can help, both in emergency situations and during treatment chronic diseases upper respiratory tract is Yox spray, application, instructions for use, which is presented on the website www..

Yox spray, what is it? What does it contain? How does it work?

This is a combined antiseptic drug. It contains polyvidone-iodine and allantoin.

Thanks to polyvidone-iodine, the drug has a bactericidal and moderate immunostimulating effect. It increases the secretion of the oral mucosa and pharynx. Thus, the mucolytic (thinning of sputum), proteolytic (enzymatic decomposition of proteins) effect of the drug is realized. Polyvidone is a molecule used to transport iodine, reducing its toxic effect on the body's cells.

The mechanism of action of iodine is aimed at changing the structure of the protein, reducing its activity in the shells of viruses, bacteria, and protozoa. And the presence of a high-molecular carrier in the drug ensures rapid penetration of iodine into the cells of pathogenic microorganisms, preserving it there for a long time. high concentrations.

Polyvidone-iodine acts against staphylococci, streptococci, proteus, candida, enterobacter and many more gram-positive and gram-negative bacteria, as well as protozoa and fungi.

Due to its bactericidal properties against many microbes, Yox spray is widely used to treat respiratory and inflammatory diseases of the upper respiratory tract. After all, it easily penetrates into the depths of the mucous membranes, damages the wall of bacteria, which gives a good positive effect in the treatment of acute respiratory diseases, so chronic pathologies upper respiratory tract.

Another component of Yox spray is alantonin. It has anti-inflammatory and reparative (restorative) properties, which enhances the effect of polyvidone-iodine. In addition, alantonin is able to suppress the growth of bacteria, soften the mucous membrane and relieve irritation, stimulate regeneration damaged cells mucous membrane of the pharynx and oral cavity.

The official instructions for use of Yox spray say that it penetrates much better through damaged skin and mucous membranes than through healthy tissue.

It is important to take into account that the components of the drug also penetrate well through the placenta and into breast milk!

More detailed information about the mechanism of action of the drug is contained in official instructions Yox spray.

Indications for use

Acute tonsillitis (tonsillitis) catarrhal, lacunar, follicular. In this case, monotherapy is contraindicated; it must be combined with antibiotics taken orally, intravenously or intramuscularly.
Chronic tonsillitis in the composition complex therapy.
Inflammatory diseases mucous membrane of the pharynx, larynx, oral cavity, aphthous stomatitis.
ARVI, adenoviral infections. The use of the drug for the first time hours or days of illness is especially effective.

How to use Yox spray (aerosol)?

Before use, you need to remove the protective cap, put on the applicator, make 2-3 presses to fill the applicator with the solution. Then insert the applicator into the oral cavity to a depth of 3-4 cm, close your lips tightly and apply 2-3 irrigations in both directions (right and left), first in one and then in the other. It is recommended to carry out such procedures 2-4 times throughout the day. After irrigation, you should not eat for 30-40 minutes.

Contraindications

Increased sensitivity to the drug, its components;
pregnancy, breastfeeding period;
uncompensated heart failure;
pronounced violation kidney and liver functions;
children under 6 years old;
carried out diagnostic test using radioactive iodine in the last 2 weeks;
It is not recommended to combine treatment with Yox spray with other local antiseptics;

Side effects

At the site of application there is a burning sensation, dryness of the oral mucosa and pharynx.
Allergic reactions: itching, rashes, urticaria, increased body temperature.
Long-term use the drug causes a condition such as iodism. It is characterized by the appearance of increased salivation, a metallic taste in the mouth, swelling of the larynx and eyelids.

Special instructions : When any side effect treatment must be stopped immediately.

Overdose

Not possible with local application, but in case of accidental ingestion large quantities drug, symptoms of acute iodine poisoning appear ( metallic taste in the mouth, nausea, vomiting, abdominal pain, loose stool). IN severe cases may develop aspiration pneumonia, swelling of the larynx, sometimes asphyxia, anuria (lack of urine), circulatory disorders. As you can see, they can develop very dangerous conditions, which often require emergency medical care.

The description of the drug is given as a free statement. For more complete information You should read the official instructions.

Yox spray- combination drug for topical use for diseases of the oral cavity and ENT organs. Upon contact with skin or mucous membranes, it releases iodine; has an antiseptic and anti-inflammatory effect.
The drug has a wide spectrum antimicrobial action.
Active against bacteria, fungi, viruses, protozoa.

Indications for use:
Indications for use of the spray Yox are:
1. Infectious and inflammatory diseases of the oral cavity and pharynx: including tonsillitis, tonsillitis, tonsillopharyngitis, glossitis, stomatitis, aphthae;
2. For treating the oral cavity and pharynx during surgical interventions on respiratory tract and oral cavity and postoperative period;
3. For the treatment of infections of the mouth and throat that occur during chemotherapy;
4. When streptococcal tonsillitis applied as additional remedy when treated with antibiotics.

Directions for use:
Spray Yox apply topically.
Remove the protective cap and install the applicator. Press the applicator 2-3 times so that the solution enters the sprayer and sprays after pressing. After this, place the applicator tube 2 - 3 cm into the oral cavity, hold your breath and press the cap twice so that one irrigation is carried out to the right, and the second to the left. It is recommended to use Yox spray 2-4 times a day. If necessary, the drug can be used more often, every 4 hours. The applicator is washed with hot water before and after use.

Side effects:
Preparation Yox the spray is usually well tolerated.
IN in some cases hypersensitivity reactions to the drug and an allergic reaction to iodine (itching, hyperemia) are possible, which requires discontinuation of the drug. Long-term use of the drug can cause the phenomenon of iodism (including: metallic taste, increased salivation, swelling of the eyes or larynx), if this occurs, you should stop using the drug and consult a doctor.

Contraindications:
Contraindications to the use of the spray Yox are: hypersensitivity to iodine and other components of the drug; pregnancy and lactation; children under 8 years old; dysfunction thyroid gland(hyperthyroidism); heart failure; Dühring's dermatitis herpetiformis; simultaneous use of radioactive iodine.

Pregnancy:
During pregnancy, use of the spray Yox contraindicated.

Interaction with other drugs:
Concomitant use of the drug is not recommended Yox with others antiseptics, intended for topical use in the oral cavity. and throats, especially those containing hydrogen peroxide, due to inactivation of the drug.

Overdose:
With topical spray application Yox An overdose is impossible, but if the solution is swallowed, symptoms of acute iodine poisoning are observed. Within 3 days after ingestion of the drug, anuria, swelling of the glottis up to asphyxia, aspiration pneumonia or pulmonary edema are observed. In some cases, circulatory problems were also observed.
In case of poisoning, symptomatic therapy is indicated. It is recommended to drink milk or brewed starch. If there is no damage to the esophagus, gastric lavage followed by administration of enterosorbent is indicated.
There is no specific antidote.

Storage conditions:
At temperatures from 10 °C to 25 °C in a place protected from light. Keep out of the reach of children.

Release form:
Yox - s spray for topical use.
30 ml in bottles made of PE (polyethylene) or PET (polyethylene terephthalate), equipped with a mechanical sprayer and a lid to protect the sprayer. Each bottle, complete with an applicator or an applicator with a rotary lever, is placed in a cardboard box with instructions for use.

Compound:
Active ingredients: povidone-iodine 2.550 g and allantoin 0.030 g per 30 ml.
Excipients:
levomenthol, citric acid monohydrate, sodium citrate dihydrate, ethanol 96%, propylene glycol, purified water.

Additionally:
Not intended for oral administration.
The drug should not be inhaled or swallowed.

Trade name drug: JOX ®

International generic name or group name:
Povidone-iodine + Allantoin&

Dosage form:

Compound:

Active substances:
Povidone-iodine 4.250 g and allantoin 0.050 g in 50 ml of solution. Povidone-iodine 8.500 g and allantoin 0.100 g in 100 ml of solution.

Excipients:
levomenthol, citric acid monohydrate, sodium citrate dihydrate, ethanol 96%, propylene glycol, purified water - up to the required volume of the drug in the package.

Description
Transparent or slightly opalescent liquid of red-brown color, indefinitely miscible with water.

Pharmacotherapeutic group:

ATX Code: A01AD; R02AA15

Pharmacological properties

Combined preparation for local use for diseases of the oral cavity and ENT organs. Upon contact with skin or mucous membranes, it releases iodine; has an antiseptic and anti-inflammatory effect.
The drug has a wide spectrum of antimicrobial action.
Active against bacteria, fungi, viruses, protozoa.

Indications for use
1. Infectious and inflammatory diseases of the oral cavity and pharynx: including tonsillitis, tonsillitis, tonsillopharyngitis, glossitis, stomatitis, aphthae;
2. For treatment of the oral cavity and pharynx during surgical interventions on the respiratory tract and oral cavity and in the postoperative period;
3. For the treatment of infections of the mouth and throat that occur during chemotherapy;
4. For streptococcal sore throats, it is used as an additional remedy in antibiotic treatment.

Contraindications.

To quickly cure cough, bronchitis, pneumonia and strengthen the immune system, you just need...

Yox - a widespread combination medicine, and Yox spray instructions for use contain instructions that this is a throat preparation with iodine, which has an antiseptic effect and has a pronounced antibactericidal and antimicrobial effect.

Yox is used for diseases of the mouth and throat, as well as in ENT practice. Produced in the form of a spray and solution.

Spray composition

The spray is based on a povidone-iodine complex.

Substance povidone- this is a sorbent, thanks to which active iodine is gradually released.

Second active ingredient drug - allantoin (contains 0.03 grams). It has anti-inflammatory, antiseptic and regeneration-stimulating effects.

Additional substances in Yox spray:

• Levomenthol;
• Ethanol (about 25% volume);
• Citric acid, its sodium salt;
• Binding component;
• Water.

The spray has the smell of alcohol and menthol, characteristic brown, taste of iodine.

Yox spray is available in glass and plastic bottles of 30 milliliters.

Yox is not an aerosol: the product does not contain a propellant. Spraying is done by pressing a mechanical sprayer.

Indications for use of the spray

The effectiveness of the drug is determined by the bactericidal properties inherent in iodine:

1. When Yox comes into contact with the mucous membranes of the mouth or throat, iodine is released from the povidone-iodine compound.
2. By interacting with microbial proteins, iodine causes them to coagulate, which leads to the death of microorganisms.
3. The substance destroys bacteria, fungi, viruses, and protozoa.
4. Microorganisms that cause respiratory infections, are not able to form resistance to the substance.

Other active substance Yoxa - allantoin - stimulates recovery processes, ending up in the mucous membrane.

According to the instructions for use, Yox is indicated for:

• Sore throat (in combination with other medications);
• Pharyngitis;
• Infectious processes that affect the oral mucosa;
• In the postoperative period;
• For preoperative treatment.

Due to irritating effect The product effectively relieves sore throat.

The instructions for use contain instructions that the product can also be used in the treatment of superinfections that occur during therapy with antibiotics, antitumor, antiviral, and antifungal drugs.

Contraindications for use and precautions

Yox spray should not be used for the following contraindications:

• Pregnancy and breastfeeding;
• Hypersensitivity to the components of the drug;
• Increased thyroid function;
• Heart failure;
• Children under 6 years old;
• Herpes form of dermatitis.

In case of laryngitis, only a doctor can prescribe the remedy.

The medication should be used very carefully in patients with renal failure.

When irrigating and rinsing, it is better not to swallow Yox.

Contact of the spray with mucous membranes should be avoided, and if the product gets into the eyes, rinse them thoroughly with cold water.

Yox tends to stain the mucous membranes of the mouth and teeth, and stains can be removed with ethanol.

How to use the product?

Spray application:

1. If the bottle of Yox has a removable applicator, you should remove it from the packaging and then put it on the sprayer, having previously removed the protective cap.
2. Press several times until the iodine preparation begins to spray.
3. Caution should be exercised: if the drug gets on clothing, it leaves permanent marks.
4. When using, you need to hold the bottle only vertically.
5. Insert the applicator tube shallowly into your mouth and point it to the left.
6. Hold your breath.
7. Press the spray applicator once.
8. Send to right side spray tube.
9. Click once.
10. Remove the applicator after completing the procedure and rinse with warm water.
11. If a non-removable spray device is installed on the Yox bottle, steps 2-9 should be followed.

The spray can be sprayed as needed 2-5 times a day.

Instructions for children

Such measures are based on objective grounds:

• The drug contains alcohol;
• When spraying, you need to hold your breath;
• Yox spray has an increased ability to irritate the mucous membrane of the throat.

However, the product has a significant advantage that makes it preferable to other antiseptics: Yox spray does not contain antibiotics or synthetic antimicrobials.

Iodine is a natural antiseptic and, in addition, takes part in metabolic processes.

Thus, there is no harm from Yox - provided that the child does not have hyperthyroidism.

Pregnancy and lactation

According to the instructions for use, Yox cannot be used during pregnancy and lactation. There have been no studies on the effect of the drug on children, but two components - alcohol and iodine - are absorbed from the mucous membrane.

The amounts of these substances in a spray dose are microscopic. However, the same iodine, for example, is a highly active substance, daily requirement which even in pregnant women does not exceed 0.2 milligrams. A whole bottle contains about 14 milligrams of iodine.

Despite the ban on the use of the product, doctors prescribe it during pregnancy:

1) Firstly, the substance iodine is deposited in the body: about 10 milligrams are stored in the thyroid gland, another about 5-7 milligrams are stored in other organs. The absorption of the substance from the drug is insignificant: such an amount cannot affect the balance of iodine in the body. Oversaturation of the body with iodine occurs as a result of prolonged and systematic use of drugs or foods rich in iodine.

In this case, oversaturation expresses itself with obvious signs:

• The appearance of a metallic taste,
• Edema,
• Increased salivation
• Allergic manifestations.

The use of Yox cannot lead to overdose.

2) Iodine is still necessary for a pregnant woman. In areas where consumption of seafood rich in this element is low, iodine intake is required for the health of the unborn child and pregnant woman.

3) Thirdly, Yox spray based on iodine is an extremely effective drug.

Taken together, the above factors indicate that the benefits of using the drug outweigh the possible negative consequences.

The restriction on use for lactating women is explained by the fact that the mammary gland is also involved in storing iodine. Thus, nature provided for the substance to be supplied to the child through mother’s milk.

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Interaction with other drugs

Yox is not allowed to be used in parallel with radioactive iodine.

Side effects

Yox is usually very well tolerated, but among adverse reactions can diagnose allergies, manifested by hyperemia and itching. With prolonged use, excessive salivation, swelling of the throat, xerostomia, and a metallic taste are possible.

Analogs of Yox spray

The medicine does not have exact analogues containing povidone-iodine and allantoin.

There are 2 iodine-based medicines available in pharmacies (release form - solution and spray), which can be used for respiratory diseases:

Iodinol

Lugol exists in Lithuanian and Russian versions. Iodinol - drug Russian production. Active ingredient in both cases iodine appears.

In Lugol, the substance is mixed with glycerol, which gives the drug an enveloping effect. Iodinol is aqueous-alcohol solution Yoda.

Which is better - Yox or Lugol?

Two fundamental differences should be highlighted:

• Lugol - aqueous solution with glycerol;
• Yox is an aqueous-alcoholic solution of the povidone-iodine complex.

These differences allow us to make the following comments about the benefits of these drugs.

Benefits of Yox:

• The presence of iodine in combination with povidone promotes a longer antimicrobial effect;
• Alcohol solutions are considered more effective antiseptics than water solutions.

Lugol's advantages:

• The absence of alcohol in the composition makes the spray more appropriate for use in children;
• The substance glycerol makes the product viscous, the liquid envelops and remains on the mucous membrane for a long time.

In addition, Lugol has a more affordable price.

However, consumers who have used both drugs prefer Yox.

Yox spray

Yox spray(Jox spray)

Basic physical and chemical characteristics: clear liquid red-brown in color with possible slight opalescence;

Compound. 1 ml of spray includes polyvidone-iodine 85 mg, allantoin 1 mg;

other ingredients: propylene glycol, menthol, citric acid monohydrate, sodium dihydrogen citrate, ethanol, purified water.

Release form of the medicinal product. Spray.

Pharmacotherapeutic group. Medicines, used for throat diseases. Antiseptics. ATC code R02AA20.

Action of the medicine. Pharmacodynamics. Polyvidone-iodine releases iodine upon contact with skin or mucous membranes, which has a wide spectrum of antimicrobial action due to direct action on proteins of microorganisms. The drug also includes allantoin, which is characterized by an anti-inflammatory effect.

Pharmacokinetics. When polyvidone-iodine is applied topically to intact skin, iodine absorption is minimal. When used in the oral cavity, in the vagina and on damaged skin (severe burns), there is a more pronounced systemic absorption of iodine, which may result in interference with thyroid functions. Iodine in the body is converted into iodides, which accumulate mainly in thyroid gland and are excreted mainly by the kidneys, and also in small quantities with feces, saliva, and sweat. Iodides pass through the placental barrier and penetrate into mother's milk.

Indications for use. Angina is catarrhal, follicular, lacunar; streptococcal tonsillitis (with simultaneous treatment antibiotics); chronic tonsillitis; pharyngitis, glossitis, aphthous stomatitis, first symptoms of flu.

Method of use and dose. Remove the protective cap and put on the applicator. Press the Yox spray applicator 2-3 times so that the solution enters the sprayer and, after pressing, is sprayed. After this, insert the applicator tube 2-3 cm into the oral cavity, close your mouth, hold your breath and apply 1-3 moisturizers to the right side, and then to the left side. Apply, as a rule, 2–4 times a day, if necessary – every 4 hours. The applicator must be rinsed with hot water before and after use.

Side effect. The drug is well tolerated. Symptoms of hypersensitivity occurred only occasionally, it is possible allergic reaction on iodine (itching, hyperemia, urticaria), which requires stopping the use of the drug. IN isolated cases a short-term sensation of burning pain at the site of use (mainly in children) or a feeling of dryness in the mouth was detected.

Long-term use of polyvidone-iodine may cause iodism (metallic taste, increased salivation, swelling of the eyes or larynx, pulmonary edema, skin rash, violations gastrointestinal tract).

Contraindications. Hypersensitivity to iodine or other components of the drug. Pregnancy, lactation period. Hyperfunction of the thyroid gland, decompensated cardiac, renal failure, studies or therapy with radioactive iodine (in the period 2 weeks before and after the study or therapy). Childhood under 8 years old.

Overdose. With the recommended local use of the drug in the mouth or pharynx, no cases of overdose have been observed. However, in the case of ingestion of iodine solution, acute poisoning. Patients first felt a metallic taste in the mouth, vomiting, stomach pain and diarrhea began. During days 1–3, anuria, swelling of the glottis followed by asphyxia, aspiration pneumonia or pulmonary edema were observed. In some cases, even severe circulatory disorders were observed.

Treatment is symptomatic and initially includes standard measures to prevent further absorption from the gastrointestinal tract. The patient should drink milk and brewed starch. If the esophagus is not damaged, gastric lavage can be performed. In addition, it is necessary to accept activated carbon and 1–5% sodium thiosulfate solution, which ensures the restoration of iodine into iodide. There is no specific antidote.

Features of use. The drug is not intended for internal use.

The drug should not be inhaled and/or swallowed. If within 3 days the patient’s condition does not improve or an adverse effect or unusual sensation is observed, a doctor’s consultation is necessary. It is not advisable to simultaneously use Yox with other medications prescribed for use in the mouth and throat.

For laryngitis, the drug can be used only in exceptional cases.

The drug contains 19% ethanol and does not include sugar.

Older children should use the drug with caution, taking into account the possibility of laryngospasm.

The drug should be used with caution in patients with liver failure. In such patients, the level of transaminases may increase, so it is necessary to monitor it in the blood serum.

Using Yox does not affect your ability to drive. vehicles and mechanisms.

Interaction with drugs. It is not recommended to combine the drug with other antiseptics for the mouth and throat, primarily with hydrogen peroxide. Yox is incompatible with renewal agents, alkaloid salts and substances that are acidic.

Storage conditions and periods. The drug should be stored at temperatures up to 25°C in a place protected from light. The drug should be kept out of the reach of children.

Shelf life – 4 years.