Spanish Fly for two - how they affect libido in women and men
Contents Biologically active additive based on an extract obtained from a beetle with a fly (or fly...
Histamine H1 receptor blocker, ethanolamine derivative. It has a strong antihistamine and antipruritic effect with a rapid onset of action and a duration of up to 12 hours, prevents the development of vasodilation and contraction of smooth muscles induced by histamine.
Possessing an anti-allergic effect, it reduces the permeability of blood vessels, capillaries, inhibits exudation and the formation of edema, reduces itching, and has an m-anticholinergic effect.
Suction
After oral administration, clemastine is almost completely absorbed from the gastrointestinal tract. Cmax in blood plasma is reached in 2-4 hours.
Distribution
The binding of clemastine to plasma proteins is 95%. It is excreted in breast milk in small quantities.
Metabolism and excretion
Excretion from plasma has a two-phase character, the corresponding T 1/2 is 3.6 ± 0.9 h and 37 ± 16 h. Clemastine undergoes significant metabolism in the liver. Metabolites are mainly (45-65%) excreted in the urine; unchanged active substance is found in the urine only in trace amounts.
Tablets white or almost white, round, flat, beveled edge, scored and engraved "OT" on one side.
Excipients: lactose monohydrate - 107.66 mg, corn starch - 10.8 mg, talc - 5 mg, povidone - 4 mg, magnesium stearate - 1.2 mg.
5 pieces. - blisters (2, 3, 6) - packs of cardboard.
10 pieces. - blisters (1, 2, 3, 6) - packs of cardboard.
Inside, adults and children over 12 years of age are prescribed 1 tab. (1 mg) morning and evening. In cases that are difficult to treat, the daily dose can be up to 6 tablets. (6 mg).
Children aged 6-12 years are prescribed 1/2-1 tab. before breakfast and at night.
Tablets should be taken before meals with water.
Symptoms: an overdose of antihistamines can lead to both a depressant and a stimulating effect on the central nervous system. CNS stimulation is more common in children. Manifestations of anticholinergic action may also develop: dry mouth, fixed pupil dilation, flushing of the upper half of the body, gastrointestinal disorders (nausea, epigastric pain, vomiting).
Treatment: if the patient does not vomit spontaneously, then it should be artificially induced (only if the patient's consciousness is preserved). If 3 hours or a little more have passed since taking the drug, gastric lavage can be performed using isotonic sodium chloride solution. You can also prescribe a saline laxative. Symptomatic therapy is also indicated.
Tavegil ® potentiates the action of drugs that depress the central nervous system (hypnotics, sedatives, tranquilizers), m-anticholinergics, and ethanol.
Incompatible with the simultaneous use of MAO inhibitors.
Determining the frequency of adverse reactions: very often (≥1 / 10); often (≥1/100,<1/10); нечасто (≥1/1000, <1/100); редко (≥1/10 000, <1/1000); очень редко (<1/10 000).
From the nervous system: often - increased fatigue, drowsiness, sedation, weakness, feeling of fatigue, lethargy, impaired coordination of movements; infrequently - dizziness; rarely - headache, tremor, stimulating effect.
From the digestive system: rarely - dyspepsia, nausea, vomiting, gastralgia; very rarely - constipation, dry mouth; in some cases - loss of appetite, diarrhea.
On the part of the respiratory system: rarely - thickening of bronchial secretions and difficulty in sputum separation, a feeling of pressure in the chest and difficulty breathing, nasal congestion.
From the side of the cardiovascular system: rarely - a decrease in blood pressure (more often in elderly patients), extrasystole; very rarely - palpitations.
From the senses: rarely - a violation of the clarity of visual perception, diplopia, acute labyrinthitis, tinnitus.
From the urinary system: very rarely - frequent urination, difficulty urinating.
From the hemopoietic system: rarely - hemolytic anemia, thrombocytopenia, agranulocytosis.
Dermatological reactions: rarely - skin rash, photosensitivity.
Allergic reactions: rarely - anaphylactic shock.
Tavegil ® should be used with caution in patients with stenosing gastric ulcer, pyloroduodenal obstruction, bladder neck obstruction, as well as prostatic hypertrophy accompanied by urinary retention, increased intraocular pressure, hyperthyroidism, diseases of the cardiovascular system (including . with arterial hypertension).
The use of the drug Tavegil ® is contraindicated during pregnancy and lactation (breastfeeding).
To prevent distortion of the results of skin prick tests for allergens, the drug must be discontinued 72 hours before allergy testing.
The tablets contain lactose, so the drug is not recommended for patients suffering from rare congenital diseases associated with galactose intolerance, severe lactase deficiency and malabsorption of glucose-galactose.
Pediatric use
Tavegil ® in the form of tablets is contraindicated in children under the age of 6 years. For the treatment of children over the age of 1 year, Tavegil ® can be used in the form of a solution for intravenous and intramuscular administration.
Influence on the ability to drive vehicles and control mechanisms
Clemastine has a slight sedative effect (from mild to moderate in intensity), so patients taking Tavegil ® are advised to refrain from driving vehicles, working with mechanisms, as well as from other activities that require increased attention and speed of psychomotor reactions.
Tavegil is a blocker of histamine H 1 receptors; antiallergic agent.
Dosage forms of Tavegil:
The composition of the tablets (in 1 pc.):
The composition of the solution (in 1 ml):
The composition of the syrup (in 5 ml):
In the form of tablets and syrup, Tavegil is used to treat the following diseases / conditions:
In the form of injections, Tavegil is prescribed in the following cases:
Both dosage forms of the drug are contraindicated in the following cases:
Intravenously and intramuscularly, Tavegil, in addition, is forbidden to be administered to patients with fructose intolerance.
As for the use of Tavegil in pediatrics: in the form of a solution and syrup, the drug is contraindicated in children under 1 year old, in the form of tablets - up to 6 years.
Intra-arterial administration of the solution is prohibited!
Regardless of the dosage form, Tavegil is prescribed with caution in such cases as:
Tavegil tablets should be taken orally before meals with water.
Children over 12 years of age and adults are prescribed 1 tablet 2 times a day (morning and evening). In severe cases, the daily dose may be increased to 6 tablets.
Children aged 6 to 12 years are indicated to take 1 / 2 -1 tablet before breakfast or at night.
In the form of syrup, adults and children over 12 years of age are prescribed Tavegil 10 ml in the morning and evening. In severe cases, the daily dose may be increased to 60 ml.
For the convenience of dosing the syrup, a measuring cup is included in the kit.
Tavegil solution is intended for intravenous and intramuscular administration.
Adults are administered 2 mg (contents of 1 ampoule) 2 times a day (morning and evening).
For prophylactic purposes, the drug is administered intravenously in a stream slowly (for at least 2-3 minutes) at a dose of 2 mg immediately before a possible reaction to the use of histamine or the development of an anaphylactic reaction. If necessary, Tavegil is diluted with 5% glucose solution or sodium chloride solution in a ratio of 1:5.
For children, the daily dose is determined depending on their weight - 0.025 mg / kg - and divided into 2 injections. Enter intramuscularly.
The side effects described below are classified as follows: very often - more than 1 case out of 10 (1/10); often - less than 1/10, but more often than 1/100; infrequently - less than 1/100, but more often than 1/1000, rarely - less than 1/1000, but more often than 1/10000; very rarely - less than 1/10000, including isolated cases.
Possible side effects of Tavegil:
Tavegil can affect the results of skin prick tests for allergens, so it should be canceled 72 hours before allergy testing.
Clemastine has a sedative effect, so during treatment it is recommended to refrain from driving vehicles, working with mechanisms and engaging in other activities associated with reaction speed and increased concentration.
Tavegil enhances the effect of ethanol, m-anticholinergics and drugs that depress the central nervous system (tranquilizers, hypnotics and sedatives).
Clemastine is incompatible with MAO inhibitors.
Keep out of the reach of children at a temperature of 15-30 °C.
Shelf life of tablets and solution - 5 years, syrup - 3 years.
Member of the Association of Homeopaths of Ukraine, participant of scientific and practical conferences and research works.
Instructions for use Tavegil refers it to the pharmacological group of H1-histamine receptor blockers. The drug quickly eliminates the manifestations of allergies in all age groups. It has an antihistamine effect. It is characterized by local anesthetic activity, reduces capillary permeability, inhibits the formation of edema, and reduces itching. The antihistamine effect persists for 11 hours.
The active substance is clemastine, a pyrrolidine derivative.
The tablet is milky in color, round, flat in shape, has bevelled edges and engraving, contains 1.34 mg of clemastine hydrofrumate, while clemastine is 1 mg. Auxiliary components:
Tavegil in ampoules may have a yellowish tint. 1 ml contains 1.34 mg of hydrofurmat (this is 1 mg of the active substance), and 1 ampoule contains 2.68 mg of clemastine hydrofurmate (which is 2 mg of the active ingredient). Excipients:
In 5 ml of clemastine furamat syrup - 670 mcg, the actual active ingredient - 500 mcg. In addition, the composition of the syrup includes:
Adults and adolescents over 12 years of age are shown 1 tablet in the morning and evening with water. Children 6-12 years old are prescribed half a tablet.
The drug is taken to relieve negative manifestations:
The appointment requires special care and observation in dynamics in patients with the following diseases:
Note! When taking the remedy, refrain from operating complex mechanisms.
Adults are prescribed one tablet twice a day. Take before meals with plenty of water.
The largest daily dose for adults is 6 tablets, which corresponds to 6 mg of the active substance. Reception of the maximum daily dose is permissible in severe cases and must be agreed with the attending physician.
Without medical supervision, it is permissible to take one or two tablets per day for no more than five days.
Attention! Refrain from drinking alcohol during treatment with Tavegil. The interaction of ethanol and clemastine negatively affects the liver and nervous system. When taking the drug, drowsiness and dizziness may occur, so for this period, refuse to drive a car.
The drug is given twice a day (morning and evening). A single dose for a child is:
The maximum daily dose is 6 tablets in severe cases, with severe allergies.
The medicine is taken before meals with a sufficient amount of liquid. The tablet can be crushed if it is difficult for the child to swallow it whole.
Until the age of five, Tavegil tablets are not prescribed.
The average cost of the drug in different countries.
Attention! Tavegil solution is not administered intra-arterially.
The injection solution is used only in cases where the patient is in serious condition:
Injections are made in the standard dosage:
Intravenously or intramuscularly, 1 ampoule is administered per day, no more than 3 days in a row - then under the supervision of a physician.
Injections are made when a faster effect is needed in response to an allergic reaction, including a severe one.
If the remedy is used to prevent the occurrence of an anaphylactic reaction or a response to the administration of histamine, Tavegil in ampoules is administered intravenously - 2 ml. Additionally, dilute the injection liquid with saline in a ratio of one to five.
Tavegil injections are not prescribed for:
You can not give an injection if a precipitate or flakes has formed at the bottom of the ampoule.
Before intravenous administration, Tavegil in ampoules is diluted with saline or glucose solution. To do this, take 5 ml of saline for 1 ml of the drug.
Intramuscular injections are indicated for adults and children over 12 years of age. The effect appears after 10-20 minutes:
To properly inject intramuscularly:
Tavegil in the form of an ointment is not available. If necessary, local use of antihistamines can be used with a similar effect. Most effective:
Take twice a day before breakfast and at night. A single dosage depends on the age of the child:
Syrup for children under one year is contraindicated.
Relief after taking the drug occurs after 30 minutes and lasts for 10-12 hours. The drug must be taken before meals.
Store the drug at a temperature not exceeding 35 degrees. Shelf life is 5 years from the date of production (see on the packaging).
Children over 12 years old can be prescribed all dosage forms.
For six-year-olds, the recommended dose is no more than 5 ml of syrup or 1/2 tablet twice a day. The drug is given in the morning and evening, preferably before meals. The medicine is washed down with a sufficient amount of water, not juices.
After taking the drug, children may develop side effects:
For five-year-olds, the recommended standard dose is no more than 5 ml of syrup twice a day. The syrup is given before breakfast and after dinner. The drug is immediately washed down with water - half a glass.
Eliminates such unpleasant allergy symptoms:
The effect of the drug lasts about 12 hours.
For four years, the recommended daily dose is 5 ml of syrup twice a day. The syrup is given before breakfast and after dinner. The drug is washed down with clean water, not juices.
When taking, observe the dosage. Exceeding the indicated doses can lead to:
Babies under three years of age are shown no more than 2.5 ml of syrup twice a day. The remedy is given before feeding. The syrup can be diluted in a few teaspoons of water, or given to a child with clean water.
Tavegil is safe for the child's body, subject to the recommended dosages and the absence of contraindications:
The drug is not prescribed for children under one year old.
As analogues for babies up to a year use:
During pregnancy, Tavegil is used with sufficient justification - when the possible risk to the fetus is lower than the expected benefit to the pregnant woman.
During pregnancy, the minimum effective dose is selected:
During lactation, Tavegil is contraindicated.
The drug is replaced only after consultation with a specialist.
The active substance is diphenhydramine. It is used orally, intramuscularly, intravenously, topically, rectally.
The course of treatment is no more than two weeks.
Candles are administered 1-2 times a day after an enema, depending on age:
Contraindication to the use of Demidrol is hypersensitivity to any substance of the composition.
The price of the drug Dimedrol:
The action of the drug Tavegil is longer than that of Dimedrol. Also, the drug in question is more active than Diphenhydramine in terms of anti-allergic effect. In addition, it has a less pronounced sedative, hypnotic effect, so it can be taken during the day.
The active substance is chloropyramine hydrochloride (25 mg).
Adults are prescribed one tablet up to four times a day. The highest daily dose is not more than 2 mg per kilogram of body weight. Children are given 1/2 tablet, taking into account age:
Contraindications:
Suprastin cost:
The active ingredient is promethazine hydrochloride (25 mg).
Possesses the expressed antiallergic activity. Contraindicated in allergic reactions caused by the use of fanotiazine agents. It is characterized by a pronounced sedative effect, and is not prescribed to persons whose profession involves a quick motor and mental reaction.
Contraindications to the use of Pipolfen:
Adults in / in or / m administered 25 mg of solution per day - the standard dose. If necessary, re-introduce 12.5-25 mg / m through.
For the prevention and treatment of vomiting, a single dose of 25 mg is used. The maximum daily dose allowed in especially severe cases is 150 mg.
Children older than 2 months are given intramuscular injections 3-5 times a day. The dosage is calculated on the basis of 0.5-1 mg per kg of body weight.
Dragee can not be divided, so the drug is prescribed for children only from 6 years old. At the age of 6-14 years, 1 tablet is prescribed 3-4 times a day. The maximum daily dosage for adults is 0.075 g.
Pipolfen cost:
The cost varies by region, pharmacy chain. Average cost in the Moscow region:
Clemastine (clemastine)
◊ Pills white or almost white, round, flat, with a beveled edge, with a line and engraved "FROM" on one side.
Excipients: lactose monohydrate - 107.66 mg, corn starch - 10.8 mg, talc - 5 mg, - 4 mg, magnesium stearate - 1.2 mg.
5 pieces. - blisters (2, 3, 6) - packs of cardboard.
10 pieces. - blisters (1, 2, 3, 6) - packs of cardboard.
Histamine H1 receptor blocker, ethanolamine derivative. It has a strong antihistamine effect with a rapid onset of action and a duration of up to 12 hours, prevents the development of vasodilation and contraction of smooth muscles induced by histamine.
Possessing an anti-allergic effect, it reduces the permeability of blood vessels, capillaries, inhibits exudation and the formation of edema, reduces itching, and has an m-anticholinergic effect.
Suction
After oral administration, it is almost completely absorbed from the gastrointestinal tract. Cmax in blood plasma is reached in 2-4 hours.
Distribution
The binding of clemastine to plasma proteins is 95%. It is excreted in breast milk in small quantities.
Metabolism and excretion
Excretion from has a two-phase character, the corresponding T 1/2 is 3.6 ± 0.9 h and 37 ± 16 h. Clemastine undergoes significant metabolism in the liver. Metabolites are mainly (45-65%) excreted in the urine; unchanged active substance is found in the urine only in trace amounts.
WITH caution Tavegil should be used in patients with stenosing gastric ulcer, with pyloroduodenal obstruction, with obstruction of the bladder neck, as well as prostatic hypertrophy, accompanied by urinary retention, with increased intraocular pressure, hyperthyroidism, diseases of the cardiovascular system (including arterial hypertension).
inside adults and children over 12 years old appoint 1 tab. (1 mg) morning and evening. In cases that are difficult to treat, the daily dose can be up to 6 tablets. (6 mg).
Children aged 6-12 years appoint 1/2-1 tab. before breakfast and at night.
Tablets should be taken before meals with water.
Determining the frequency of adverse reactions: very often (≥1 / 10); often (≥1/100,<1/10); нечасто (≥1/1000, <1/100); редко (≥1/10 000, <1/1000); очень редко (<1/10 000).
From the nervous system: often - increased fatigue, drowsiness, sedation, weakness, feeling of fatigue, lethargy, impaired coordination of movements; infrequently - dizziness; rarely - headache, tremor, stimulating effect.
From the digestive system: rarely - dyspepsia, nausea, vomiting, gastralgia; very rarely - constipation, dry mouth; in some cases - loss of appetite, diarrhea.
From the respiratory system: rarely - thickening of bronchial secretions and difficulty in sputum separation, a feeling of pressure in the chest and difficulty breathing, nasal congestion.
From the side of the cardiovascular system: rarely - lowering blood pressure (more often in older patients), extrasystole; very rarely - palpitations.
From the sense organs: rarely - a violation of the clarity of visual perception, diplopia, acute labyrinthitis, tinnitus.
From the urinary system: very rarely - frequent urination, difficulty urinating.
From the hematopoietic system: rarely - hemolytic anemia, thrombocytopenia, agranulocytosis.
Dermatological reactions: rarely - skin rash, photosensitivity.
Allergic reactions: rarely - anaphylactic shock.
Symptoms: an overdose of antihistamines can lead to both inhibitory and stimulating effects on the central nervous system. CNS stimulation is more common in children. Manifestations of anticholinergic action may also develop: dry mouth, fixed pupil dilation, flushing of the upper half of the body, gastrointestinal disorders (nausea, epigastric pain, vomiting).
Treatment: if the patient does not vomit spontaneously, then it should be artificially induced (only if the patient's consciousness is preserved). If 3 hours or a little more have passed since taking the drug, gastric lavage can be performed using isotonic solution. You can also prescribe a saline laxative. Symptomatic therapy is also indicated.
Tavegil potentiates the action of drugs that depress the central nervous system (hypnotics, sedatives, tranquilizers), m-anticholinergics, and ethanol.
Incompatible with the simultaneous use of MAO inhibitors.
To prevent distortion of the results of skin prick tests for allergens, the drug must be discontinued 72 hours before allergy testing.
The tablets contain lactose, so the drug is not recommended for patients suffering from rare congenital diseases associated with galactose intolerance, severe lactase deficiency and malabsorption of glucose-galactose.
Pediatric use
Tavegil in the form of tablets is contraindicated in children under the age of 6. For treatment of children over the age of 1 year Tavegil can be used in the form of a solution for intravenous and intramuscular administration.
Influence on the ability to drive vehicles and control mechanisms
Clemastine has a slight sedative effect (from mild to moderate in intensity), therefore, patients taking Tavegil are advised to refrain from driving vehicles, working with mechanisms, as well as from other activities that require increased attention and speed of psychomotor reactions.
The drug should be stored out of the reach of children at a temperature not exceeding 30 ° C. Shelf life - 5 years.
Tavegil is an antiallergic blocker of histamine H1 receptors. Instructions for use indicate that 1 mg tablets, syrup, injections in ampoules for injection are prescribed to patients for the relief of allergy attacks of various origin and intensity. Reviews of patients and doctors confirm that this drug helps allergic reactions in children and adults.
Tavegil is available in the form of tablets for oral use and a solution for injection into a muscle or vein.
The active component of Tavegil, clemastine, is a blocker of H1-histamine receptors and belongs to ethanolamine derivatives. It is characterized by a strongly pronounced antihistamine and antipruritic effect. The drug begins to act quickly, the duration of action reaches 12 hours.
Clemastine prevents the development of vasodilation and smooth muscle contraction, which histamine induces. Tavegil exhibits antiallergic and m-anticholinergic action, reduces itching, slows down the formation of edema, inhibits exudation, reduces the permeability of blood vessels and capillaries.
What helps Tavegil? Tablets, syrup and injections are prescribed for:
Indications for the use of Tavegil are also:
Inside, adults and children over 12 years of age are prescribed 1 tablet (1 mg) in the morning and evening. In cases that are difficult to treat, the daily dose may be up to 6 tablets (6 mg). Children aged 6-12 years are prescribed 1/2-1 tablet before breakfast and at night. Tablets should be taken before meals with water.
Adults and children over 12 years of age are prescribed 10 ml of syrup (1 mg) in the morning and evening. In cases that are difficult to treat, the daily dose can be up to 60 ml of syrup (6 mg).
Intramuscularly or intravenously, adults are prescribed 2 mg (2 ml, i.e. the contents of one ampoule). For the purpose of prevention, immediately before the possible occurrence of an anaphylactic reaction or a reaction in response to the use of histamine, the drug is administered intravenously in a jet at a dose of 2 mg (2 ml).
Solution for injection in an ampoule can be further diluted with isotonic sodium chloride solution or 5% glucose solution in a ratio of 1:5. In / in the injection of Tavegil should be carried out slowly, for more than 2-3 minutes. Children are prescribed at a dose of 25 mcg / kg per day in 2 injections.
See also: how to take an analogue for allergies.
Before starting therapy with the drug, you should carefully read the attached instructions, since Tavegil has a number of contraindications:
Relative contraindications to the administration of the drug are: angle-closure glaucoma, anuria, prostatic hyperplasia, hyperthyroidism, impaired liver and kidney function, diseases of the cardiovascular system. Also, with caution, the drug should be prescribed to patients over 65 years of age.
During pregnancy, Tavegil is used only if the expected benefit of therapy for the mother outweighs the potential risk to the fetus. Should not be used during lactation, because. clemastine is excreted in small amounts in breast milk.
Contraindicated in children under 1 year old. Children over 1 year old: 0.025 mg/kg per day intramuscularly divided into 2 injections.
Tavegil can distort the results of skin prick tests for allergens, so it is necessary to stop taking it no later than 72 hours before the start of allergy testing.
If symptoms of the development of undesirable effects appear, you should consult a doctor. During the period of use of clemastine, patients are advised to refrain from driving vehicles and mechanisms.
Tavegil enhances the effect of neuroleptics (antipsychotics), hypnotics, sedatives, m-anticholinergics. Simultaneous use with MAO inhibitors is not allowed.
According to the structure, analogues are determined:
Analogues have a similar effect:
The average cost of Tavegil (tablets 1 mg) in Moscow is 220 rubles. The drug can be bought at a pharmacy without a doctor's prescription.
Tablets should be stored in a place protected from children for no more than 4 years from the date of manufacture. Ampoule packaging should be kept in a cool, dark place out of the reach of children. The expiration date is indicated on the packaging and is 2 years from the date of manufacture, provided that the ampoules are properly stored.
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