Akriderm 0 05 instructions for use. Akriderm cream - instructions for use. What to use, ointment or cream - rules for choosing the dosage form and variety of Akriderm

Akriderm: instructions for use and reviews

The composition of the drug includes the main component: betamethasone dipropionate .

Additional ingredients: nipagin, paraffin, propylene glycol, petroleum jelly, alcohol, emulsifying wax, disodium salt, sodium sulfite and purified water.

Release form

Akriderm is produced in the form of a cream or ointment, packaged in tubes of 15 or 30 g.

pharmachologic effect

The drug exhibits anti-inflammatory, anti-allergic, anti-exudative, anti-edematous And antipruritic Effect.

Pharmacodynamics and pharmacokinetics

This product is glucocorticosteroid local application. Its main substance, betamethasone dipropionate, is capable of inhibiting the accumulation and release of lysosomal , as well as anti-inflammatory mediators at the site of inflammation. In addition, phagocytosis is inhibited, vascular-tissue permeability is reduced, preventing the occurrence of inflammatory swelling.

Indications for use

Main indications for the use of Akriderm ointment and cream:

• various allergic skin diseases, for example: , ;
• various forms of non-allergic dermatitis.

Contraindications

• hypersensitivity to the drug;
• skin tuberculosis ;
• skin manifestations ;
• simple ;
• skin post-vaccination reactions;
• open wounds;
• children under one year of age;
• trophic ulcers;
• acne vulgaris.

Side effects

External use of GCS may be accompanied by burning, irritation, dry skin, folliculitis, hypertrichosis , the appearance of acne, hypopigmentation , . Prolonged application, especially under occlusive dressings, can cause the development purpura, skin maceration, secondary infection , prickly heat, atrophy of the skin surface and so on.

Instructions for use Akriderm (Method and dosage)

Akriderm ointment, the instructions for use of which recommend applying it to the affected surface of the skin, is used twice daily. A different therapeutic regimen may also be prescribed, taking into account the severity of the disease.

When treating mild cases, Akriderm cream, instructions for use, allows for application once, and for more severe lesions - up to several times a day.

The duration of treatment may depend on various factors: the effectiveness and tolerability of the drug, the severity of the disease and the characteristics of the patient’s body. On average, the therapeutic course is 2-4 weeks.

When improvement does not occur for a long time, urgent clarification of the diagnosis is necessary.

Overdose

When using Akriderm ointment or cream, it is difficult to get an overdose, but with prolonged application in large quantities it is quite possible. Symptoms of chronic overdose can manifest themselves as: hyperglycemia, glucosuria, suppression of the functions of the adrenal cortex, Cushing's syndrome.

In this case, symptomatic treatment is carried out. The appearance of chronic toxic effects requires gradual withdrawal of the drug.

Interaction

This external agent does not interact with other drugs.

special instructions

The appearance of signs of hypersensitivity and skin irritation during the treatment period requires stopping the use of this remedy and choosing a more suitable treatment for the patient.

Long-term therapy, application of the drug in large quantities to a large surface of the skin, the use of occlusive dressings and treatment of children can cause systemic absorption of GCS.

Treatment of children must be carried out strictly according to the indications and prescription of the doctor, which will allow monitoring the possible development of systemic undesirable effects. It is possible that the full functioning of the hypothalamic-pituitary-adrenal system is suppressed, symptoms of hypercortisolism appear, growth excretion decreases, and intracranial pressure increases.

The development of side effects occurs especially often when the drug is applied to the skin of the face. Therefore, the therapeutic course should not be longer than 5 days.

The use of Akriderm in ophthalmology is not allowed. It is necessary to avoid getting it into the eyes and mucous membranes.

If treatment with the drug has been carried out for a long time, gradual withdrawal of therapy is recommended.

Terms of sale

On prescription.

Storage conditions

A suitable place for storage is at room temperature, out of reach of children.

Best before date

Use during pregnancy

How safe is it to use this product? at , not installed. Therefore, the use of drugs in this group during this period is allowed when the potential benefit significantly outweighs the likely risk. It is important not to use the product for a long time in high dosages.

Akriderm's analogs

The price of analogues is approximately 470-550 rubles.

Reviews about Akriderm

It should be noted that various skin problems bother many people who use this particular product to solve them. As reviews of Akriderm cream show, they prefer to apply it when mild lesions appear on the skin: slight itching, redness and irritation.

At the same time, reviews of Akriderm ointment show that this form of the drug is usually used by people who know the exact diagnosis. However, even in this case, treatment does not always occur without complications. The main reason for this is long-term use of the drug, which can lead to loss of effectiveness, development of addiction and side effects.

Also, some users report that when they used this remedy for the first time, it helped to eliminate the symptoms of the disease quite quickly. The next time the drug was used, longer treatment was required and the effect was less durable.

Sometimes Akriderm is used for acne and a similar situation is noted. At first, the rashes go away quickly, but then they come back again and this happens much more often. Moreover, the appearance of pigmented and light areas and deterioration of the skin structure are noted. Although such users do not even know exactly how to use Akriderm ointment, what it helps with and how long to apply it.

By the way, such cases are described quite often. This happens because this drug is not able to influence the causes of the development of dermatitis, relieving the manifestations of the disease. Therefore, the use of Akriderm can only bring temporary relief, and then the development of complications.

However, this particular drug helps many patients alleviate the acute period of dermatitis. Of course, at the same time the causes of the disease are corrected: various , reducing drugs, adsorbents, medicinal decoctions. To remove external damage to the skin, use ointment or cream.

In addition, users are often interested in whether Akriderm ointment is hormonal or not? The fact is that some patients are afraid to use hormonal drugs. But in fact, you just need to strictly follow the application regimen and adhere to the prescribed dosage. Therefore, experts do not recommend using any medications without a prescription from a competent doctor.

Akriderm price, where to buy

The price of Akriderm ointment is from 85 rubles.

The price of Akriderm cream varies between 100-300 rubles.

You can buy any form in any Russian pharmacy, as well as outside the country.

For example, the price in Ukraine is 80-385 UAH depending on the volume of packaging.

• Online pharmacies in Russia Russia
• Online pharmacies in Kazakhstan Kazakhstan

ZdravCity

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Pharmacy Dialog

Akriderm SK ointment (tube 15g) Akrikhin OJSC

Instructions for use

Akriderm instructions for use

Dosage form

Cream for external use 0.05% white or almost white.

Compound

Betamethasone dipropionate 64 mg, which corresponds to the content of betamethasone 50 mg

Excipients: methyl parahydroxybenzoate - 0.2 g, solid paraffin - 9 g, petroleum jelly - 3 g, propylene glycol - 5 g, liquid paraffin - 18 g, emulsion wax - 7 g, disodium edetate - 0.1 g, sodium sulfite - 0.05 g, purified water - up to 100 g.

Pharmacodynamics

Side effects

With local use of glucocorticosteroids, the following may be observed: burning, irritation, dry skin, folliculitis, hypertrichosis, acne-like rashes, itching, stretch marks, miliaria, hypopigmentation, perioral dermatitis. With long-term use, as well as the use of occlusive dressings, skin maceration, secondary infection, skin atrophy, prickly heat, purpura, local hirsutism, telangiectasia. When applied to large surfaces of the body, mainly in children, systemic side effects of glucocorticosteroids may occur (gastritis, ulceration of the gastrointestinal mucosa, hyperglycemia, glycosuria, reversible inhibition of adrenal function, manifestation of Cushing's syndrome).

If you experience any side effects not described in the instructions, you should consult a doctor.

Selling Features

Available without a prescription

Special conditions

The corticosteroid betamethasone dipropionate has anti-inflammatory, antiallergic, antiexudative, decongestant and antipruritic effects. Inhibits the accumulation of leukocytes, the release of lysosomal enzymes and anti-inflammatory mediators at the site of inflammation, inhibits phagocytosis, reduces vascular tissue permeability, and prevents the formation of inflammatory edema.

Indications

allergic skin diseases (including acute, subacute and chronic contact dermatitis, occupational dermatitis, seborrheic dermatitis, atopic dermatitis, solar dermatitis, neurodermatitis, pruritus, dyshidrotic dermatitis, eczema);

Acute and chronic forms of non-allergic dermatitis;

Psoriasis.

Contraindications

Hypersensitivity to any of the components of the drug, bacterial, fungal skin diseases, skin tuberculosis, skin manifestations of syphilis, chicken pox, herpes simplex, skin post-vaccination reactions, open wounds, trophic leg ulcers, rosacea, acne vulgaris, skin cancer, nevus, atheroma, melanoma, hemangioma, xanthoma, sarcoma, lactation period and children under 1 year of age.

Drug interactions

No interaction of the drug with other drugs has been identified.

Prices for Akriderm in other cities

Mode of application

Dosage

The duration of treatment depends on the effectiveness and tolerability of therapy and is 2-4 weeks.

If clinical improvement does not occur, it is necessary to clarify the diagnosis.

Overdose

Excipients: methyl parahydroxybenzoate - 0.2 g, solid paraffin - 9 g, - 3 g, propylene glycol - 5 g, liquid paraffin - 18 g, emulsion wax - 7 g, disodium edetate - 0.1 g, sodium sulfite - 0.05 g, purified water - up to 100 g

50 g - aluminum tubes (1) - cardboard packs.

◊ Ointment for external use 0.05% from white to white with a yellowish tint, translucent.

Excipients: propyl parahydroxybenzoate - 0.05 g, liquid paraffin () - 4 g, isopropyl myristate - 1 g, petroleum jelly - up to 100 g.

15 g - aluminum tubes (1) - cardboard packs.
30 g - aluminum tubes (1) - cardboard packs.

pharmachologic effect

Indications

• allergic skin diseases (including acute, subacute and chronic contact dermatitis, occupational dermatitis, solar dermatitis, neurodermatitis, pruritus, dyshidrotic dermatitis);
• acute and chronic forms of non-allergic dermatitis;
• psoriasis.

Contraindications

• lupus;
• viral skin infections;
• vaccination;
• perioral dermatitis;
• rosacea (rosacea);
• hypersensitivity to any component of the drug.

Dosage

Akriderm should be applied in a thin layer to the affected areas 1-3 times a day, lightly rubbing. The duration of treatment should be no more than 3 weeks.

Use of the drug Akriderm in children under 12 years of age carried out under the supervision of a doctor.

Side effects

Possible: burning, irritation and dry skin, folliculitis, hypertrichosis, hypopigmentation, allergic contact dermatitis, skin atrophy, stretch marks and miliaria. In case of side effects, you should consult a doctor.

Overdose

Symptoms: excessive or prolonged use of local corticosteroids can cause inhibition of the function of the pituitary-adrenal system, which can cause the development of secondary and symptoms of hypercortisolism, including Cushing's syndrome.

Treatment: appropriate symptomatic treatment is indicated. Acute symptoms of hypercortisolism are usually reversible. If necessary, correction of electrolyte imbalance is indicated. In case of chronic toxic effects, gradual withdrawal of GCS is recommended.

Drug interactions

There are no clinically significant interactions with other drugs.

special instructions

If there is no effect of treatment within two weeks, it is recommended to consult your doctor for a possible clarification of the diagnosis. If irritation or hypersensitivity reaction is observed when using the drug, treatment should be stopped and consult your doctor. For secondary fungal or bacterial infections, appropriate medications must be used. If there is no immediate positive effect, the use of Akriderm should be discontinued until all signs of infection are eliminated.

Long-term use of the drug on the skin of the face is not recommended. Akriderm should not be used in the eye area, because... in this case, the development of cataracts, glaucoma, fungal infection and exacerbation of herpetic infection is possible.

Use in pediatrics

Children may be more susceptible to the use of topical corticosteroids that cause hypothalamic-pituitary-adrenal (HPA) axis suppression than older patients due to increased drug absorption associated with their larger surface area to body weight ratio. The following side effects were observed in children taking local corticosteroids: suppression of the HPA system function, Cushing's syndrome, linear growth retardation, delayed weight gain, increased intracranial pressure. Symptoms of adrenal suppression in children include decreased cortisol levels and lack of response to ACTH stimulation. Increased intracranial pressure is manifested by bulging of the fontanel, headache, and bilateral papilledema.

Pregnancy and lactation

Due to the fact that the safety of the use of local corticosteroids in pregnant women has not been established, the use of drugs of this class during pregnancy is justified only if the benefit to the mother clearly outweighs the possible harm to the fetus. Drugs in this group should not be used by pregnant women in large doses for a long time.

Since it has not yet been established whether glucocorticosterones, when applied topically and systemically absorbed, can penetrate into breast milk, a decision should be made to stop breastfeeding or discontinue the drug, taking into account how necessary its use is for the mother.

Use in childhood

Children may be more susceptible to the use of topical corticosteroids that cause hypothalamic-pituitary-adrenal (HPA) axis suppression than older patients due to increased drug absorption associated with their larger surface area to body weight ratio. The following side effects were observed in children taking local corticosteroids: suppression of the HPA system function, Cushing's syndrome, linear growth retardation, delayed weight gain, increased intracranial pressure. Symptoms of adrenal suppression in children include decreased plasma cortisol levels and lack of response to ACTH stimulation. Increased intracranial pressure is manifested by bulging of the fontanel, headache, and bilateral papilledema.

Conditions for dispensing from pharmacies

The drug is approved for use as a means of OTC.

Storage conditions and periods

The drug should be stored out of the reach of children at a temperature of 15 to 25°C. Shelf life - 2 years.

Composition and release form

Cream for external use 0.05% - 100 g:

• Active substance: betamethasone dipropionate 64 mg, which corresponds to the content of betamethasone 50 mg.
• Excipients: methyl parahydroxybenzoate - 0.2 g, solid paraffin - 9 g, petroleum jelly - 3 g, propylene glycol - 5 g, liquid paraffin - 18 g, emulsion wax - 7 g, disodium edetate - 0.1 g, sodium sulfite - 0.05 g, purified water - up to 100 g.

30 g - aluminum tubes (1) - cardboard packs.

Description of the dosage form

Cream for external use 0.05% white or almost white.

pharmachologic effect

GCS has anti-inflammatory, antipruritic and vasoconstrictor effects.

Pharmacodynamics

The corticosteroid betamethasone dipropionate inhibits the accumulation of leukocytes, the release of lysosomal enzymes and pro-inflammatory mediators at the site of inflammation, inhibits phagocytosis, reduces vascular tissue permeability, and prevents the formation of inflammatory edema.

Gentamicin is a broad-spectrum antibiotic from the aminoglycoside group. Has a bactericidal effect against pathogens of primary and secondary bacterial skin infections. Active against gram-negative bacteria: Pseudomonas aeruginosa, Aerobacter aerogenes, Escherichia coli, Proteus vulgaris, Klebsiella pneumoniae; ;Gram-positive bacteria: ;Streptococcus spp. ;(susceptible strains of group A beta- and alpha-hemolytic streptococcus), ;Staphytococcus spp. ;(coagulase-positive, coagulase-negative and some penicillinase-producing strains). Inactive against anaerobes, fungi and viruses.

Clotrimazole has an antifungal effect by disrupting the synthesis of ergosterol, which is an integral part of the cell membrane of fungi. Active against: Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum, Microsporum canis, Candida albicans, Malassezia furtur (Pityrosporum orbiculare).

Salicylic acid provides a keratolytic, antimicrobial effect, eliminates horny layers and promotes deeper penetration of GCS.

Clinical pharmacology

GCS for local use.

Indications for use

• allergic skin diseases (including acute, subacute and chronic contact dermatitis, occupational dermatitis, solar dermatitis, neurodermatitis, pruritus, dyshidrotic dermatitis);
• acute and chronic forms of non-allergic dermatitis;
• psoriasis.

Contraindications for use

• lupus;
• viral skin infections;
• vaccination;
• perioral dermatitis;
• rosacea (rosacea);
• hypersensitivity to any component of the drug.

Use during pregnancy and children

Due to the fact that the safety of the use of local corticosteroids in pregnant women has not been established, the use of drugs of this class during pregnancy is justified only if the benefit to the mother clearly outweighs the possible harm to the fetus. Drugs in this group should not be used by pregnant women in large doses for a long time.

Since it has not yet been established whether glucocorticosterones, when applied topically and systemically absorbed, can penetrate into breast milk, a decision should be made to stop breastfeeding or discontinue the drug, taking into account how necessary its use is for the mother.

Use in children

Side effects

Possible: burning, irritation and dry skin, folliculitis, hypertrichosis, hypopigmentation, allergic contact dermatitis, skin atrophy, stretch marks and miliaria. In case of side effects, you should consult a doctor.

Drug interactions

There are no clinically significant interactions with other drugs.

Dosage

Akriderm should be applied in a thin layer to the affected areas 1-3 times a day, lightly rubbing. The duration of treatment should be no more than 3 weeks.

The use of Akriderm in children under 12 years of age is carried out under the supervision of a physician.

Overdose

Symptoms: excessive or prolonged use of local corticosteroids can cause inhibition of the function of the pituitary-adrenal system, which can cause the development of secondary adrenal insufficiency and the appearance of symptoms of hypercortisolism, including Cushing's syndrome.

Treatment: Appropriate symptomatic treatment is indicated. Acute symptoms of hypercortisolism are usually reversible. If necessary, correction of electrolyte imbalance is indicated. In case of chronic toxic effects, gradual withdrawal of GCS is recommended.

Precautionary measures

If there is no effect of treatment within two weeks, it is recommended to consult your doctor for a possible clarification of the diagnosis. If irritation or hypersensitivity reaction is observed when using the drug, treatment should be stopped and consult your doctor. For secondary fungal or bacterial infections, appropriate medications must be used. If there is no immediate positive effect, the use of Akriderm should be discontinued until all signs of infection are eliminated.

Long-term use of the drug on the skin of the face is not recommended. Akriderm should not be used in the eye area, because... in this case, the development of cataracts, glaucoma, fungal infection and exacerbation of herpetic infection is possible.

Use in pediatrics

Children may be more susceptible to the use of topical corticosteroids that cause hypothalamic-pituitary-adrenal (HPA) axis suppression than older patients due to increased drug absorption associated with their larger surface area to body weight ratio. The following side effects were observed in children taking local corticosteroids: suppression of the HPA system function, Cushing's syndrome, linear growth retardation, delayed weight gain, increased intracranial pressure. Symptoms of adrenal suppression in children include decreased plasma cortisol levels and lack of response to ACTH stimulation. Increased intracranial pressure is manifested by bulging of the fontanel, headache, and bilateral papilledema.