Iodine instructions for use. Alcohol solution of iodine: instructions and use. Indications for the use of iodine preparations

Iodine coagulates proteins to form iodamines. It has a bactericidal effect and also has cauterizing and tanning properties. Irritates receptors of mucous membranes and skin. Participates in the formation of thyroxine. During contact with skin or mucous membranes, 30% is converted into iodides, the rest is converted into active iodine. Iodine is partially absorbed. The absorbed part enters organs and tissues. Iodine preparations have the most pronounced effect on the thyroid gland. If there is iodine deficiency in the body, they help restore the impaired formation of thyroid hormones. When the body contains iodine in normal quantities, it inhibits the formation of thyroid hormones, reduces the sensitivity of the thyroid pituitary gland to TSH and blocks the secretion of TSH by the pituitary gland. The effect of iodine preparations on metabolism is manifested by an increase in dissimilation processes. In atherosclerosis, they lead to a slight decrease in the content of beta-lipoproteins and cholesterol in the blood; they also increase lipoproteinase and fibrinolytic activity of blood serum and inhibit the rate of blood clotting. Iodine promotes the resorption and softening of syphilitic gums when they accumulate in them. But with the accumulation of iodine in the foci of tuberculosis, it leads to an increase in inflammation processes in them. When iodine is released by the excretory glands, the glandular tissue is irritated and secretion increases. This is due to the stimulation of lactation (in small doses) and expectorant effect. But in large doses, iodine can inhibit lactation. It is mainly excreted by the kidneys, to a lesser extent by the intestines, mammary and sweat glands.

Indications

Inflammatory and other diseases of the mucous membranes and skin; cuts; abrasions; microtraumas; neuralgia; myositis; atherosclerosis; inflammatory infiltrates; syphilis (tertiary); ozena; chronic atrophic laryngitis; endemic goiter; hyperthyroidism; chronic mercury and lead poisoning; disinfection of wound edges, skin of the surgical field, and surgeon's fingers.

Method of application of iodine and dose

Apply externally to the affected areas of the skin, larynx, into the conjunctival sac (3 times a day, 1 drop), instill into the nose (2 times a day, 5 drops). Orally, diluted in milk, after meals, for atherosclerosis - 1–2 times a day for 4 weeks, 5–12 drops, repeated courses (2–3 times a year), for syphilis - 2–3 times a day, 5 –50 drops, for children 2–3 times a day, 3–5 drops of a 5% solution.
If you miss the next dose of iodine, take it as you remember, and take the next dose after the set time from the last use.
When used together with yellow mercury ointment, it is possible to form mercury iodide in the tear fluid, which has a cauterizing effect. With prolonged use, phenomena of iodism are possible.

Contraindications for use

Hypersensitivity, for oral administration: nephritis, pulmonary tuberculosis, furunculosis, chronic pyoderma, acne, urticaria, hemorrhagic diathesis, adenomas (including the thyroid gland), age under 5 years, pregnancy.

Restrictions on use

No data.

Use during pregnancy and breastfeeding

The use of iodine is contraindicated during pregnancy. When breastfeeding, it can be used according to indications when prescribed by a doctor.

Side effects of iodine

For external use: skin irritation; with prolonged use on large surfaces - iodism (rhinitis, lacrimation, Quincke's edema, urticaria, salivation, acne).
When taken orally: tachycardia, skin allergic reactions, nervousness, increased sweating, sleep disturbances, diarrhea.

Interaction of iodine with other substances

Iodine is pharmaceutically incompatible with sedimentary white mercury (an explosive mixture is formed), ammonia solutions, and essential oils. An acidic or alkaline environment, the presence of pus, fat, and blood reduce the antiseptic activity of iodine. Iodine reduces the goitrogenic and hypothyroid effects of lithium preparations.

Overdose

When inhaling iodine vapor, damage to the upper respiratory tract occurs (laryngobronchospasm, burn); when concentrated iodine solutions are ingested, severe burns of the digestive tract occur, the development of hemoglobinuria, hemolysis; the lethal dose is approximately 3 g. Treatment: gastric lavage with 0.5% sodium thiosulfate solution, intravenous administration of sodium thiosulfate 30% - up to 300 ml.

◊ Alcohol solution for external use 1% transparent, red-brown in color, with a characteristic odor.

Excipients: ethanol 95%.

15 ml - bottles.

pharmachologic effect

Elemental iodine has pronounced antimicrobial properties. Elemental iodine preparations are characterized by a pronounced local irritating effect on tissue, and in high concentrations - a cauterizing effect. The local effect is due to the ability of elemental iodine to precipitate tissue proteins. Preparations that remove elemental iodine have a much less pronounced irritating effect, and iodides have local irritating properties only in very high concentrations.

The nature of the resorptive effect of elemental iodine and iodides preparations is the same. During the resorptive effect, iodine preparations have the most pronounced effect on the functions of the thyroid gland. In case of iodine deficiency, iodides help restore impaired synthesis of thyroid hormones. With normal iodine content in the environment, iodides inhibit the synthesis of thyroid hormones, the sensitivity of the thyroid gland to pituitary TSH decreases and its secretion by the pituitary gland is blocked. The effect of iodine preparations on metabolism is manifested by increased dissimilation processes. When they cause a slight decrease in the concentration of cholesterol and beta lipoproteins in the blood; in addition, they increase the fibrinolytic and lipoproteinase activity of blood serum and slow down the rate of blood clotting.

Accumulating in syphilitic gums, iodine promotes their softening and resorption. However, the accumulation of iodine in tuberculosis lesions leads to an increase in the inflammatory process in them. The release of iodine by the excretory glands is accompanied by irritation of the glandular tissue and increased secretion. This is due to the expectorant effect and stimulation of lactation (in small doses). However, in large doses, iodine preparations can cause suppression of lactation.

Pharmacokinetics

Upon contact with skin or mucous membranes, 30% is converted into iodides, and the rest into active iodine. Partially absorbed. The absorbed part penetrates tissues and organs and is selectively absorbed by the thyroid gland. It is secreted mainly by the kidneys, intestines, sweat and mammary glands.

Indications

For external use: infectious and inflammatory skin lesions, injuries, wounds, myalgia.

For local use: chronic tonsillitis, atrophic rhinitis, purulent rhinitis, trophic and varicose ulcers, wounds, infected burns, fresh thermal and chemical burns of I-II degree.

For oral administration: prevention and treatment of atherosclerosis, tertiary.

Contraindications

Hypersensitivity to iodine. For oral administration - pulmonary tuberculosis, nephritis, nephrosis, adenomas (including the thyroid gland), furunculosis, acne, chronic pyoderma, hemorrhagic diathesis, urticaria, children under 5 years of age.

Dosage

When applied externally, iodine is used to treat damaged areas of the skin.

For oral administration, the dose is set individually, depending on the indications and age of the patient.

Topically used for washing lacunae and supratonsillar spaces - 4-5 procedures at intervals of 2-3 days, for irrigation of the nasopharynx - 2-3 times a week for 2-3 months, for instillation into the ear and rinsing - for 2-4 weeks; in surgical practice and for burns, gauze napkins applied to the affected surface are moistened as needed.

Side effects

For external use: rarely - skin irritation; with prolonged use on large wound surfaces - iodism (rhinitis, urticaria, salivation, lacrimation, acne).

When taken orally: allergic skin reactions, tachycardia, nervousness, sleep disturbances, increased sweating, diarrhea (in patients over 40 years of age).

When we hear the word “iodine”, we immediately imagine a medicine that is used to disinfect a wound and treat inflammation. With iodine you can quickly relieve bruises and bruises on the skin. But, above all, it is a chemical element whose properties make it a truly universal remedy. It is everywhere around us, although in small quantities: in soil and minerals, in plants and water. It is practically insoluble in water and can evaporate at normal temperatures.

What is iodine

Iodine is an element that is responsible for the normal growth of all mammals, including humans. If it did not exist in nature, life would look different; It’s even hard to imagine what people would be like.

Iodine enters the human body through water and food, and through inhaled air and through the skin - in small doses; then accumulates in the thyroid gland. Participates in the synthesis of thyroxine and triiodothyronine - hormones necessary for the normal functioning of the thyroid gland. When the thyroid gland is functioning normally, its cells extract iodine from the blood. At the same time, metabolism proceeds normally - which means that iodine affects the functioning of the whole organism.

It also helps the formation of cells necessary for our body, a kind of cleaners that capture and destroy foreign microorganisms and damaged cells. This element is of paramount importance for the normal growth and development of children and adolescents; participates in the formation of bones and cartilage, in protein synthesis, stimulates mental abilities, improves performance and neutralizes fatigue.

Iodine is also necessary for lipid metabolism and metabolism in subcutaneous tissue. It promotes the breakdown of fat and prevents the appearance of cellulite. A normal amount of iodine in the body helps burn fat during diets, keeps you active and gives you energy, and promotes healthy skin, nails and teeth.

How does iodine deficiency manifest itself and the consequences of its deficiency?

Iodine deficiency and deficiency develops in residents of areas where the soil and water are poor in this element. The deficiency condition is aggravated if the food of these people is poor in complete proteins and vitamins C and A. Then, “Hashimoto’s goiter” develops - a disease of the thyroid gland; immunity weakens and metabolic processes in the body are disrupted; memory deteriorates, the affected person’s energy is quickly depleted and fatigue is constantly felt; he is irritable, often has a headache, his weight changes sharply, he experiences severe sweating and drowsiness. Iodine deficiency diseases are the basis of cardiovascular diseases and respiratory disorders.

Thyroxine and the thyroid gland

- iodinated thyroid hormone. It is an inactive compound representing 90% of the gland's production. It is capable of being converted into the active phase and converted under the action of enzymes into triiodothyronine. Two iodine-containing hormones optimize energy processes in the body, affect the nervous system and the functions of the heart, kidneys and liver.

Thyroxine affects blood pressure - increases it; mobility and mental activity depend on the level of the same hormone. Thyroxine affects metabolism and the speed of thought processes. This affects your heart rate.

With normal levels of the hormone in the blood, there is no excess weight, unless there are diseases that contribute to excess weight. This type of effect is associated with the role of thyroxine in metabolic rate. When a person with normal thyroxine levels eats more than necessary, the body produces more thyroxine and active fat burning follows.

The daily need for iodine depends on the type and physiological state of the person; features of puberty, pregnancy, breastfeeding, etc., which require taking high doses. The World Health Organization has established the following daily iodine requirements for adults and children:

• 50 mcg for infants and children up to 12 months;
• 90 mcg for children 2-6 years old;
• 120 mcg for children 7-12 years old;
• 150 mcg for adolescents over 12 years of age;
• 100 mcg for adults;
• 200 mcg for pregnant and nursing mothers.

Treatment and prevention

Treatment with iodine for internal use requires dosage. It is taken for iodine deficiency. 90% of the element comes through food, and the remaining 10% through water and air. That is why a walk along the seashore is an addition to the menu, where the air is saturated with healing vapors of iodine compounds. When taken, iodine affects metabolism, enhances the functions of the thyroid gland and promotes the production of thyroid hormones, reduces cholesterol in the blood, and is necessary in the treatment of atherosclerosis. In addition, the microelement increases the fibrinolytic activity of the blood.

What is iodine tincture used for?

Tincture of iodine is an alcohol solution that is used to disinfect tissue around the damaged area. This is a good antiseptic, which is also used for purulent skin lesions. If treatment with iodine tincture on the damaged area is insufficiently effective, consultation with a doctor is necessary. In some therapeutic practices, iodine is also used to treat respiratory diseases and nasopharyngeal infections.

Official medicine defines iodine tincture as a topical remedy with a therapeutic effect on the skin and mucous membranes. The solution is also used as an additional remedy for muscle inflammation (applied to the skin over the problem muscle).

Composition of iodine tincture

Tincture of iodine is an alcohol solution. The classic formula contains 5% iodine in a 70% ethanol solution of potassium iodide and a small amount of purified water. In practice, weak solutions of 0.5%, 1%, 2%, 5 to 7% are used for treatment of mucous membranes and wounds.

A standard 5% tincture is also used to disinfect untreated drinking water; you will need 10 drops of tincture per liter of water.

Use of Povidone-iodine

Povidone-iodine is a product for local external use in the form of a solution or ointment (a chemically stable complex of polyvinylpyrrolidone and iodine). Used in the treatment of dermatoses with secondary bacterial infection, affecting wounds and trophic ulcers, infections, the drug is effective in painful conditions with bacteria, fungi and viruses. It is applied in a thin layer several times during the day.

How do iodine vapors affect humans?

Inhaling iodine vapor on the seashore, an old therapeutic approach to strengthening the immune system and respiratory system. It is recommended to take walks along the seashore 7-10 days within half an hour to an hour after sunrise. When there is a high concentration of beneficial ions in the air and the effect is most effective.

Direct inhalation of iodine vapor obtained when passing into a gaseous state is dangerous: they are toxic, and their entry through the respiratory tract causes irritation and burns.

At the same time, iodine vapor is used at home for irritation of the upper respiratory tract. To do this, add five drops of iodine to boiled water and inhale the steam, covered with a towel. Breathe like this for 15-20 minutes twice a day.

With a small amount of iodine tincture - 5%, you can make a solution for gargling, for problems with the mouth and throat. Add one teaspoon of table salt and soda, and 2-3 drops of iodine to a glass of warm water. Stir and gargle 5-8 times a day. An excellent disinfectant.

Use as an antiseptic in the treatment of wounds

Iodine is a proven antiseptic with a proven effect in eliminating pathogenic microorganisms. Iodine solution is regularly used when treating operating areas in surgery. Antiseptic preparations containing iodine are used in medical interventions, for example, when placing catheters, punctures, etc.

Iodine solution is used to disinfect the skin around the injury, with open wounds. The tincture is also suitable for those cases when it is necessary to dry an injured skin area. Iodine should not be used on an open wound or deep cut.

How to treat nail fungus with iodine at home

To treat fungus on toenails, a tincture is used; a solution with a concentration of 5% is suitable. When a fungal infection occurs, nail treatment is carried out every day, and for preventive purposes - once every three days. With regular use, you may feel a slight burning sensation, if it intensifies or you notice redness, treatment is suspended.

How does the procedure work? Each infected nail is treated with one drop of tincture. The procedure is performed twice a day. This causes your nails to turn yellow - we hope you won’t wear sandals like this. Also, you won't be able to use nail polish until the fungus is treated.

Iodine solution also works on fungi on the feet and between the toes. On average, it takes about 20 days to cure fungus on the skin and nails with iodine.

How does iodine help the thyroid gland with hypothyroidism?

When a person has hypothyroidism, the production of thyroid hormones decreases. This condition occurs when the gland tissue is damaged or due to iodine deficiency in the body. It is important to diagnose the cause of this condition; if this is the so-called “endemic goiter”, it is recommended to take iodine-containing drugs. A diet with an emphasis on iodine-containing foods, such as beets, garlic, walnuts, onions, chokeberries, strawberries and fish is also recommended.

Radioiodine therapy - treatment with radioactive iodine

Radioactive iodine is useful in the treatment of goiter, thyroid cancer, and hyperthyroidism. This type of treatment requires a hospital stay, for thyrotoxicosis - one day, and for tumor formation - up to 5 days. For treatment and diagnosis, special tools and equipment are needed.

How to gargle

You can gargle with iodine tincture - this is an old method from traditional medicine. It is used for sore throat and is suitable for adults and adolescents. Some recipes recommend five drops of a 5% iodine solution per 50 ml of water; rinsing is carried out in the morning and evening. According to other recommendations, the proportion is as follows: 7-8 drops of tincture are dripped into a glass of water and a teaspoon of salt and baking soda is added.

It is important not to overdose as there is a risk of throat irritation. It is safer to take a three percent tincture or buy water enriched with iodine ion vapor at a pharmacy. Iodine concentrate is also available with varying ionic contents of thermally stable iodine. It is used to prepare various iodized products according to special recipes.

Can I take iodine?

Self-medication while taking iodine tincture is dangerous and can cause burns to the respiratory tract; In addition, there is no consensus on the effectiveness of this approach, and at the same time there are warnings about subsequent dysbiosis. However, supporters of traditional methods of treatment use some recipes that they consider safe. We will quote them with the condition that you will use them after consulting your doctor, in order to avoid unwanted side effects and reactions:

• Five drops of iodine tincture are dripped into a glass of water or fresh milk and drunk for heavy metal poisoning, endocrine diseases and inflammation of the respiratory tract;
• A drop of iodine tincture in a glass of milk helps with atherosclerosis; add a spoonful of honey and drink once a week - in the evening, after meals;
• When coughing, drink a glass of hot water with three drops of iodine;
• If you have a runny nose in the initial stages, drink half a glass of water with five drops of iodine tincture. Inhaling the vapors of an iodine solution also helps with a runny nose.
• A liter of water from an uncertified source can be “legalized” with 1-3 drops of tincture; drink after half an hour.

Use for indigestion

An old practice is to suppress severe indigestion with tincture of iodine. Suitable therapy for adults is 2-3 drops of solution per glass of water, which is drunk immediately. The solution has an unpleasant taste, so you should have some kind of bite to suppress nausea, such as a piece of lemon.

Iodine and aspirin for joint pain

Iodine with aspirin is a well-known combination from traditional medicine practice. It is believed to help with arthritis and rheumatism; It is used as an external remedy and relieves pain and stiffness. It is very simple to prepare a cheap antibiotic; five crushed aspirin tablets are dissolved in 10 ml of iodine tincture. The ointment is applied to the sore spot in the evening before bedtime and loosely wrapped with a bandage. With the same ingredients, you can make a healing oil by mixing white Vaseline from the pharmacy.

For pain in the legs, you can take a partial bath with warm water, in which 25 g of sea salt and 12 drops of iodine tincture are dissolved. Take 15 minutes every evening for two weeks.

For psoriasis

According to the recommendation of users on the Internet: you can use 5% iodine tincture against psoriasis. It is believed that baths diluted with iodine help in the healing process of psoriasis plaques. If your feet are affected, every evening fill a bowl with hot water and a tablespoon of sea salt, and add 20-30 drops of iodine to it. Keep your feet in it until the water cools down. Then, using a cotton swab soaked in the cooled solution, apply to the remaining stains and leave on the smeared area until dry. This therapy is practiced until the spots begin to disappear and the itching stops.

However, this approach only partially solves the problems of this disease. Since the underlying disease is associated with the reactions of the immune system, it is important to balance it, and healthy eating, cleansing the body, etc. help with this.

For hair

Iodine deficiency always affects the condition of the hair; the lack of this element affects the functions of the thyroid gland, and deviations in it become noticeable through symptoms such as hair loss, dry and brittle hair, fatigue, and irritability.
Regarding hair, you need to act in two directions: taking iodine-containing drugs or supplements if the doctor has identified abnormalities, or using an external mask and shampoos with added iodine.

The simplest approach is to prepare an herbal tea suitable for your hair type with the addition of five drops of iodine. A universal means of strengthening hair and restoring its shine and elasticity is green tea, to which 5-8 drops of iodine are added when cooled.

Make the following hair mask with iodine tincture:

Beat a raw egg with a spoonful of cream or whole yogurt; add 5-8 drops of five percent iodine tincture; lubricate the hair roots and massage, and then distribute over the entire length. Rinse with shampoo and warm water after an hour or an hour and a half.

Iodine and baby oil for hair removal

The combination of iodine and baby oil produces a mixture that can be used to painlessly remove unwanted hair. This homemade recipe calls for a two percent tincture solution, which is mixed very thoroughly with the oil. One tablespoon of iodine solution, and one coffee cup of baby oil. The treated area is lubricated and wiped with a cloth after five minutes. This mask not only removes hair, but also stops the growth of new ones after it is repeated 2-3 times.

Pregnancy test with iodine

In order to determine a possible pregnancy, many women use iodine. This method, despite its unconventionality, is a very common, and most importantly, harmless way to determine the presence of pregnancy.

This method is often used because of its reliability. Also, it should be noted that iodine solution is almost always at hand, which makes it possible to find out if you are pregnant without any additional means. Iodine allows a woman to know if she is pregnant even in the smallest stages.

Scientists have found that an iodine solution, when in contact with the urine of a pregnant woman, gives an oxidation reaction. This happens due to the fact that iodine meets with female hormones, which are produced by the body only during gestation. Under the influence of this oxidation reaction, the iodine solution changes its usual brown color to purple.

An interesting fact is that in translation from ancient Greek the word “iodine” is translated as “purple”. It was named so because since ancient times, this substance has been used to check the freshness of certain products, as well as their starch content.

How to take a pregnancy test using iodine

For the test you will need:

1. A small piece of napkin or paper.
2. Pipette.
3. Urine jar. It can be either glass or plastic. Urine must be collected in the morning.

The procedure itself is very simple.

To begin, apply a few drops of urine onto a napkin or paper using a pipette. Then take a few drops of iodine and apply it to the same piece of paper or napkin. After this you only need to wait a few seconds.

If the place where iodine was applied changes its color to purple or pink, this result indicates a positive test result. If the color is dark blue or brown, this indicates the absence of pregnancy.

This pregnancy test is popular because it is not difficult to carry out, and the test result can be seen immediately with the naked eye.

Sugar syrup for bees with nosematosis

Magic powder: iodine and ammonia

Mixing these components is one of the experiments in recreational chemistry. To implement it, you need equal amounts of ammonia and iodine from the pharmacy. As a result of the chemical reaction, a precipitate and a clear liquid are formed - our interest is directed to the precipitate. Filter it thoroughly and spread a small amount onto sheets of paper. Dry in the shade. Traces of fallen sediment, when touched, emit a crackling sound - thunder. This is a chic room, especially among teenagers.

Iodine on potatoes. Detection of starch in milk

If we drop a few drops of iodine tincture on potatoes, they will turn blue - this is due to the presence of starch in the tubers. This reaction can be used to test whether starch is added to fresh milk to mask dilution with water. Even one drop of iodine in a cup of milk is enough to check the content of the product - if starch is present, the reaction will be exactly the same as for potatoes.

Lugol's solution is named after its creator, Lugol. The drug was created in the early 19th century and has been used for a long time as an effective antiseptic, including for internal use and enemas. It is a combination of iodine, potassium iodide and water or glycerin. The drug contains up to 5% iodine and practically resembles the well-known tincture of iodine, without alcohol. Lugol's solution is used for wounds and skin irritations, as a prophylactic against endemic goiter, atherosclerosis, in the complex treatment of syphilis, and much more.

After the Chernobyl accident, it was one of the main preventive measures for the population to prevent the accumulation of radioactive iodine in the thyroid gland.

Lugol's throat solution

For diseases of the nasopharynx and affected mucous membranes, the places are wiped with a cotton swab dipped in a solution - the mucous membranes of the oral cavity, throat with atrophic rhinitis of the nasal cavity, as well as chronic inflammation of the tonsils. It is usually recommended to repeat the procedure two or three times a day for 2-3 days.

Lugol's spray - for children and adults

The solution has an unpleasant taste, so a spray is recommended for children, with which it is easy to reach the problem area of ​​diseased mucous membranes. One injection is prescribed 4-6 times a day for 2-3 days; then we continue 2-3 times a day, up to three times a week for two months.

Foods rich in iodine

The main source of iodine for the body is food. We will specifically mention iodized and sea salt because they help maintain normal iodine intake. The most iodine-rich seafood products are fish, tuna, cod, shrimp, as well as eggs, milk and dairy products, potatoes, green beans, plums and blueberries, seaweed, bananas and strawberries. Canned corn and white bread are healthy.

Which foods contain the most iodine and selenium?

Seafood and dairy products must be consumed due to the rich presence of selenium in them. Selenium deficiency also impairs thyroid function and causes various problems in the gastrointestinal tract, vision and makes the immune system more vulnerable to negative effects. Taking optimal doses of iodine and selenium is mentioned among cancer prevention measures.

Seeds and nuts, especially Brazil nuts, are another source of selenium. It is also present in berries such as strawberries and grapes, grains and meat.

Prices for drugs with iodine

Information about these prices is for 2017. Changes could occur.

Povidone-iodine

Povidone-iodine is the active ingredient in many antiseptics - products used to treat wounds, burns, infections and inflammation, such as Braunovidone, Braunol, Iodosept, etc. As a rule, Povidone-iodine derivatives are not expensive and are easy to use and last a long time . The price is 250-500 rubles.

Iodine tablets

The available "iodine" form is potassium iodide tablets, equivalent to 94 mg of iodine. A package of 100 tablets costs about 100 rubles. The product is recommended for problems with the thyroid gland and is taken in doses and duration determined by a specialist.

Yodoral

Yodoral is a dietary supplement - potassium iodide capsules from Optimox Corporation. Sold on iherb.com, costs approx. 2500 rub. for 180 capsules and 1400 rubles for 90 capsules. Before taking this drug, consult your doctor about the dosage and duration of use.

Iodoform

Another antiseptic and disinfectant; crystalline volatile substance with a strong odor - for purulent wounds and ulcers. 25 grams in a dark glass bottle cost approximately 500 rubles. It is a compound of iodine, hydrogen and carbon. It is also used as an anesthetic.

Iodixanol

X-ray contrast agent for cardiac angiography, coronary angiography, cerebral angiography, abdominal aortography, examination of blood vessels, urography, examination of the gastrointestinal tract, myelography, arthrography. Also applicable to studies of children. Iodixanol price from 18,000 to 40,000 rubles.

Iodomarin

A widely used iodine preparation that can be accurately dosed depending on the application. The average price is from 120 to 350 rubles.

Iodine active

An organic compound of iodine that is built into the milk protein molecule. With a lack of iodine, the microelement is actively absorbed and the excess is excreted from the body rather than entering the thyroid gland. Cost from 65 to 270 rubles per pack, depending on the number of tablets.

Endocrinol

It is a source of flavonoids and vitamin E. It helps improve the functional state of the thyroid gland. Price per pack from 190 to 400 rubles.

Contraindications

With long-term use of drugs containing iodine and hypersensitivity, responses such as runny nose, increased salivation, lacrimation, urticaria, rash, and Quincke's edema may occur. You should not use drugs with iodine for pulmonary tuberculosis, pregnancy, kidney disease, chronic pyoderma.

Overdose

Home iodine prophylaxis and self-treatment with iodine-containing products can lead to an overdose. Symptoms:

• Thirst,
• Labored breathing,
• Nausea,
• Vomit.

These symptoms require immediate medical attention.

Unregulated use of iodine supplements can cause iodine accumulation in the body, which affects the condition and function of the thyroid gland. An overdose can also have toxic effects leading to death.

In this article you can read the instructions for use of the drug Iodine. Reviews of site visitors - consumers of this medicine, as well as the opinions of specialist doctors on the use of iodine in their practice are presented. We kindly ask you to actively add your reviews about the drug: whether the medicine helped or did not help get rid of the disease, what complications and side effects were observed, perhaps not stated by the manufacturer in the annotation. Iodine analogues in the presence of existing structural analogues. Use for the treatment of injuries, wounds and other infectious and inflammatory skin diseases in adults, children, as well as during pregnancy and lactation.

Iodine- has pronounced antimicrobial properties. Elemental iodine preparations are characterized by a pronounced local irritating effect on tissue, and in high concentrations - a cauterizing effect. The local effect is due to the ability of elemental iodine to precipitate tissue proteins. Preparations that remove elemental iodine have a much less pronounced irritating effect, and iodides have local irritating properties only in very high concentrations.

The nature of the resorptive effect of elemental iodine and iodides preparations is the same. During the resorptive effect, iodine preparations have the most pronounced effect on the functions of the thyroid gland. In case of iodine deficiency, iodides help restore impaired synthesis of thyroid hormones. With normal iodine content in the environment, iodides inhibit the synthesis of thyroid hormones, the sensitivity of the thyroid gland to pituitary TSH decreases and its secretion by the pituitary gland is blocked. The effect of iodine preparations on metabolism is manifested by increased dissimilation processes. In atherosclerosis, they cause a slight decrease in the concentration of cholesterol and beta-lipoproteins in the blood; in addition, they increase the fibrinolytic and lipoproteinase activity of blood serum and slow down the rate of blood clotting.

Accumulating in syphilitic gums, iodine promotes their softening and resorption. However, the accumulation of iodine in tuberculosis lesions leads to an increase in the inflammatory process in them. The release of iodine by the excretory glands is accompanied by irritation of the glandular tissue and increased secretion. This is due to the expectorant effect and stimulation of lactation (in small doses). However, in large doses, iodine preparations can cause suppression of lactation.

Pharmacokinetics

Upon contact with skin or mucous membranes, 30% is converted into iodides, and the rest into active iodine. Partially absorbed. The absorbed part penetrates tissues and organs and is selectively absorbed by the thyroid gland. It is secreted mainly by the kidneys, intestines, sweat and mammary glands.

Indications

For external use:

• infectious and inflammatory skin lesions;
• injuries;
• wounds;
• myalgia.

For topical use:

• chronic tonsillitis;
• atrophic rhinitis;
• purulent otitis;
• trophic and varicose ulcers;
• wounds;
• infected burns;
• fresh thermal and chemical burns of 1-2 degrees.

For oral administration:

• prevention and treatment of atherosclerosis;
• tertiary syphilis.

Release forms

Alcohol solution 3% and 5%.

Tablets 80 mg.

Instructions for use

When applied externally, iodine is used to treat damaged areas of the skin.

For oral administration, the dose is set individually, depending on the indications and age of the patient.

Topically used for washing lacunae and supratonsillar spaces - 4-5 procedures at intervals of 2-3 days, for irrigation of the nasopharynx - 2-3 times a week for 2-3 months, for instillation into the ear and rinsing - for 2-4 weeks; in surgical practice and for burns, gauze napkins applied to the affected surface are moistened as needed.

Side effect

• skin irritation;
• iodism (rhinitis, urticaria, Quincke's edema, salivation, lacrimation, acne);
• skin allergic reactions;
• tachycardia;
• nervousness;
• sleep disorders;
• increased sweating;
• diarrhea (in patients over 40 years of age).

Contraindications

Hypersensitivity to iodine. For oral administration - pulmonary tuberculosis, nephritis, nephrosis, adenomas (including the thyroid gland), furunculosis, acne, chronic pyoderma, hemorrhagic diathesis, urticaria, pregnancy, children under 5 years of age.

Use during pregnancy and breastfeeding

Contraindicated for oral administration during pregnancy.

Drug interactions

Pharmaceutically incompatible with essential oils, ammonia solutions, white sedimentary mercury (an explosive mixture is formed). An alkaline or acidic environment, the presence of fat, pus, and blood weaken the antiseptic activity. Reduces the hypothyroid and goitrogenic effects of lithium preparations.

Analogues of the drug Iodine

Structural analogues of the active substance:

• Fine-crystalline iodine, instant soluble;
• Potassium iodide;
• Povidone iodine;
• Iodine balance;
• Iodomarin.

If there are no analogues of the drug for the active substance, you can follow the links below to the diseases for which the corresponding drug helps, and look at the available analogues for the therapeutic effect.

One bottle (10 ml) contains: active substance: iodine – 0.5 g, Excipients
One bottle (800 ml) contains: active substance: iodine – 40 g, Excipients– potassium iodide, ethyl alcohol, purified water.
One bottle (900 ml) contains: active substance: iodine – 45 g, Excipients– potassium iodide, ethyl alcohol, purified water.

Pharmacotherapeutic group

Antiseptic.
ATX code: D08AG03.

Pharmacological properties

Pharmacodynamics
Antiseptic. The main active ingredient is molecular iodine, which has antimicrobial and antifungal properties. Iodine is able to oxidize and denature the proteins of microorganisms, causing their death. Molecular iodine preparations are characterized by a pronounced local irritating effect on tissue, and in high concentrations, a cauterizing effect. When absorbed and released into the blood, it can have a systemic effect, participating in the synthesis of thyroid hormones.
Pharmacokinetics
Upon contact with skin, 30% is converted into iodides, and the rest remains in the form of elemental iodine. Partially absorbed from the skin surface. The absorbed portion can enter tissues and organs, being selectively absorbed by the thyroid gland. Iodine is secreted by the kidneys (mainly), intestines, sweat glands and mammary glands.
The absorption of iodine through damaged skin and mucous membranes can be significant.

Indications for use

It is used externally as an antiseptic for infectious and inflammatory skin diseases, for treating the surgical field, and for preventing infection of minor damage to the integrity of the skin.

Contraindications

Individual intolerance (including a history of hypersensitivity).
Patients with thyroid dysfunction (hyperthyroidism and adenoma) or receiving lithium therapy.
Skin treatment for furunculosis, acne, hemorrhagic diathesis, urticaria, diabetic trophic ulcers is not allowed.
Dühring's dermatitis herpetiformis.
Newborn period.

Directions for use and doses

For external use, a cotton swab is moistened with an iodine solution and used to treat affected areas of the skin. The medicine should not be used for more than 10 days. When treating the surgical field, the skin is wiped twice with a sterile gauze swab soaked in a solution of the drug. The total processing time is 4-6 minutes.

Side effect

Skin irritation, allergic reactions, including angioedema, urticaria, contact dermatitis, with prolonged use on large wound surfaces - “iodism” (lacrimation, hypersalivation, rhinorrhea, bronchorrhea, swelling of the mucous membranes).
May cause skin hemorrhages or purpuras, fever, arthralgia, lymphadenopathy and eosinophilia.

Overdose

In case of overdose, phenomena of iodism, irritation and burns are possible.
When inhaling concentrated vapors - damage to the upper respiratory tract (burn, laryngo- and bronchospasm); if concentrated solutions get inside - severe burns of the digestive tract; in case of ingestion – development of hemolysis, hemoglobinuria; the lethal dose is about 3 g.
Treatment: gastric lavage with 0.5% sodium thiosulfate solution, intravenous administration of 30% sodium thiosulfate solution - up to 300 ml. In case of a severe skin reaction to iodine, the drug should be immediately removed with 70% ethyl alcohol. It is also recommended to rinse the skin with plenty of water for 15 minutes. In case of accidental ingestion, if the patient is conscious, milk orally every 15 minutes.
Unless the drug is used for the treatment of large open wounds or is used for no more than 10 days, clinically significant systemic absorption is unlikely. Systemic toxicity may result in shock, tachycardia, fever, metabolic acidosis, and renal failure. Death may be caused by circulatory failure, swelling of the epiglottis leading to asphyxia, aspiration pneumonia or pulmonary edema.

Precautionary measures

It is not recommended to use the drug in children under two years of age due to the increased risk of hypothyroidism.
Do not allow the undiluted drug to come into contact with the mucous membranes of the mouth, eyes, vagina and rectum.
It is not recommended for use on deep or puncture wounds or serious burns, as the use of the drug may cause excessive iodine absorption and tissue irritation.
Do not use the medicine for more than ten days!
It is not recommended to treat large areas of skin with the drug.
The use of the drug may affect the results of studies of thyroid function.

Pregnancy and breastfeeding

Children

The use of the drug in newborns is contraindicated and the use of the drug in children under two years of age is not recommended due to the high probability of systemic absorption of iodine when applied externally.
Topical use in children can lead to severe skin reactions to iodine, iodism, and transient hypothyroidism.