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30.06.2020

New in the treatment of psoriasis. New remedies for psoriasis. Oral medications

A common chronic dermatosis characterized by scaly plaques and papules is called psoriasis. A new medicine for the treatment of this elusive, multifaceted disease is patented annually in the registry of pharmacological agents.

But, despite many new products, modern treatment of psoriasis has not found a universal remedy.

News in the treatment of psoriasis: internal modern remedies

Cytostatic drugs (Methotrexate) and corticosteroids (Dexamethasone, Prednisolone) - drugs with an extensive list of adverse reactions - have been replaced by glucocorticoid combination drugs. New products from psoriasis:

  • Betamethasone,
  • Betazon,
  • Diprosan

and other new generation drugs effectively relieve acute conditions.

The drugs are administered intramuscularly several times a week in a short course of treatment. Short term - new in the treatment of psoriasis, it allows you to reduce adverse reactions to a minimum.

The latest in the treatment of psoriasis: pathogenetic and etiotropic agents

Drugs that destroy proteins that can damage skin cells are an effective new product of genetic engineering.

Intravenous medications:

  • Etanercept,
  • Remicade,
  • Stelara,

belonging to the group of drugs with monoclonal antibodies - the latest in the treatment of psoriasis.

The newest drugs, administered by dropper into the patient’s bloodstream once every few weeks, neutralize the destructive effect of the protein that damages epidermal cells. In this case, the patient’s body synthesizes specific antibody proteins that match human immunoglobulin. Clinical practice has confirmed the high effectiveness of a new method of treating psoriasis

But besides this, dermatologists who use modern innovations in their practice have noted the following adverse reactions:

the appearance of hematomas on the skin.

  • Depression accompanied by apathy and drowsiness;
  • Rash, itching;
  • Arrhythmia, blood pressure instability;
  • Changes in blood composition;
  • Conjunctivitis, pneumonia with the development of pulmonary edema;
  • Thrombophlebitis, nosebleeds due to bleeding disorders,

Psoriasis News: Local Remedies

1 . Psorkutan- a modern effective drug.

Calcipotril (active substance) is an analogue of vitamin D3, which is an active metabolite. The drug applied to the skin interacts with epidermal cells,

  • suppresses pathological cell division,
  • stops the process of inflammation,
  • has an immunocorrective effect.

Psorcutan does not cause:

  • skin atrophy,
  • relapse after discontinuation of the drug,
  • combines well with PUVA therapy, which cannot be said about glucocorticoid drugs of an earlier generation.

2 .Elokom and Advantan- non-halogenated ointment preparations belonging to the fourth group of glucocorticoid agents. Available in the form of cream, emulsion, ointment. By using new treatments, patients manage to avoid a number of adverse reactions that are often observed when using other glucocorticoids.

The absence of such components as chlorine and fluorine in the composition of the products allows Ekolom and Advant to be prescribed in the form of ointments, emulsions, and creams to elderly patients and children.

3 . Active substance Dithranol has a pronounced antidermatosis effect. Suppresses inflammation and the process of reproduction of histio and hematogenous cells in it.

  • Psorax,
  • Cygnoderm,
  • Cignolin,

New products for psoriasis containing Dithranol.

The course of treatment ranges from two weeks to two months. Improvements are observed in 70% of patients. The duration of therapy and technique (long-term or short-term) are selected by the treating dermatologist.

Itching, swelling and redness (erythema) at the application site are adverse reactions that may occur.

Together with creams and ointments, tablets for psoriasis play a significant role in complex treatment. Today we will look at such effective tablets for psoriasis as Neotigazon, Methotrexate, Psorilom, Laminin, Milgamma, Lecithin and Befungin.

Treatment of psoriasis with tablets is quite successful, both inpatient and in sanatoriums and clinics. Tablets, like , are developed by dermatologists all over the world. But, unfortunately, even the most effective pills will not help.

Treatment of psoriasis with tablets is a complex therapy along with ointments, creams, and lotions. Complex therapy assigns a very important role to vitamins in the treatment of psoriasis. They have a positive effect on processes in the skin and metabolism. Many vitamins, as a remedy for psoriasis, are included in the tablets. In addition, tablets for psoriasis are quite convenient to use.

Neotigazon tablets for psoriasis

Psoriasis tablets Neotigazon are prescribed for particularly severe forms. Therapy is continued until the skin is sufficiently restored. When there are disturbances in keratinization, Neotigazon for psoriasis used for a long time, but use the minimum effective dose. The most effective tablets for psoriasis are taken with milk.

Methotrexate tablets for psoriasis

Tablets for psoriasis Methotrexate are a classic systemic treatment and bring good results, especially in severe forms. Methotrexate for psoriasis performs the function of a cytostatic drug - it suppresses excessive division of skin cells. Methotrexate tablets are similar to folic acid and have an immunosuppressive effect. Read more about this tool in the publication on our website.

Psorilom tablets

Tablets for psoriasis Psoril are included in complex treatment for skin lesions of less than 20%. Therapy lasts more than two months, after which a month's break is required. Psorilom tablets for psoriasis Do not swallow: the tablets are kept under the tongue until they dissolve on their own. There are 3 tablets per dose. You should take 9 tablets per day. Psoril should be taken separately from food.

Information from the Internet, but what is it really!? I can say with certainty that Psorilom tablets will not help in the treatment of psoriasis. They have a positive effect on the immune system, but nothing more, although this is also important for psoriasis. Read more about the drug in the article on our website.

Laminin tablets

Tablets for psoriasis Laminin have thousands of positive reviews and a lot of results. Laminin for psoriasis Provides balanced nutrition to cells, restores aging ones, and nourishes new ones. Laminin tablets increase the serotonin needed by the body, promote collagen production, and restore DNA molecules. Of course, I will add that they are ineffective for psoriasis.

Folic acid

With psoriasis, the body is deficient in folic acid, and ambiguous symptoms may occur. Folic acid for psoriasis evens out pigmentation and cleanses the skin. Effective tablets with folic acid make it possible to cope with the disease much faster and prevent megaloblastic anemia. Actively participating in hematopoiesis, folic acid is considered essential in the treatment of early stages and often contributes to complete recovery from the disease. As such, they are not effective for psoriasis, but are sometimes used in the treatment regimen.

Milgamma tablets

Milgamma tablets for psoriasis are a multivitamin that has an effect on degenerative nervous diseases. The dosage regimen is prescribed by the doctor, but in the absence of an exacerbation, a tablet per day is sufficient. Milgamma for psoriasis Contraindicated in severe form and sensitivity to the components of the drug. Milgamma is also not given to newborns and pregnant women.

Tablet Mumiyo

It is difficult to imagine curing psoriasis without Mumiyo. Healing natural balm – Mumiyo for psoriasis allows you to carry out treatment at home. The patient's condition is quickly stimulated. The use of Mumiyo in tablets allows the body to resist this serious disease. Many folk recipes include Mumiyo. The purified drug is a serious help in getting rid of psoriasis of any form. I can’t add anything on my own, I haven’t seen it in my practice.

Lecithin tablets

Tablets for psoriasis Lecithin significantly shorten the treatment time, eliminate the torpidity of the disease, and reduce the number of relapses. Lecithin has no side effects. It is recommended even for psoriasis with impaired fat metabolism and high cholesterol. Lecithin tablets for psoriasis widely used in the complex treatment of psoriasis as vitamins.

Befungin tablets

Tablets for psoriasis Befungin improve immunity in case of long-term psoriasis and restore hematopoiesis. Befungin consists entirely of natural extracts: St. John's wort, also chaga. Befungin tablets for psoriasis soften the symptoms and do not cause dependence when taken for a long time. Reception is stopped at the first signs of intolerance to the drug. Act as a means to improve the patient's condition.

The “Tablet” program about psoriasis

At the beginning of 2016 it airs on Channel 1 transmission Tablet about psoriasis, which discusses various remedies and medications for psoriasis. Channel One and the Tablet program do not cooperate with pharmaceutical companies, so the discussion of tablets and other remedies for the treatment of psoriasis occurs in the interests of viewers of our site.


Psoriasis is a very ancient disease. During its existence, humanity has accumulated a rich stock of various effective and not so effective ways to treat it. However, this skin problem, which brings a lot of inconvenience to its owner, still remains little studied, and a panacea for psoriasis has never been found. Therefore, treatment is purely individual and is carried out under the strict supervision of medical staff and the attending physician.

Modern methods of treating psoriasis will help you get rid of its painful symptoms and achieve long-term remission.

How does psoriasis manifest itself?

These are external skin changes caused by systemic disturbances in the functioning of many body systems. The skin begins to become covered with red rashes that eventually turn into scaly papules, itching, pain, and irritation appear. Wounds often bleed. The disease is difficult to treat, because getting rid of its external manifestations is not enough; it is necessary to look for the cause that caused the disorder. Alas, they are also not fully studied.

It has been proven that the genetic component plays the most important role, because the probability of getting psoriasis if your parents had it is above 80%.

In addition, the disease can be caused by:

Most often, psoriasis affects the head and joints of the limbs, although it can appear in any part of the body. Bright, bloody, scaly spots often cause inconvenience to their owner, because it may seem to others that the disease is contagious. This is another reason why it is worth educating members of society about such diseases, because it will make the lives of patients easier without turning them into “outcasts” in the eyes of uninformed people.

New treatments for psoriasis

New treatments for psoriasis are emerging every day. Although the disease is difficult to cure, you cannot give up and stop fighting it, because out of thousands of methods, there may be at least one that is relevant for a given individual case.

There are many proven methods of therapy, including:

  • drug and hardware treatment;
  • folk remedies;
  • alternative techniques.

They are aimed at reducing itching, relieving intoxication, increasing immunity, that is, mainly at relieving symptoms.

Basic methods of drug therapy

Hormonal agents

Hormonal agents (glucocorticosteroids) help fight inflammation in the body, regulate metabolism, and improve immunity. The disadvantage of this class of medications is the list of side effects and contraindications.

The most famous hormonal drug in Russia, Diprospan, is prescribed intramuscularly, by injection several times a week.

Particularly dangerous are hormonal drugs such as:

Before taking them, in addition to consulting with several doctors, it is worth reading more about the drugs on the Internet.

After all, the side effects of hormonal treatment include:

  • endocrine system disorders;
  • the appearance of kidney stones;
  • increased blood pressure and irregular heart rhythm;
  • problems with the liver, which will have to filter huge doses of toxins in short periods of time.

New generation medications

New generation medications are developed primarily through genetic engineering and are called biological. Their main purpose is not to relieve external symptoms of the disease, but to suppress cytokines that cause inflammation in the body.

Among these drugs you can find:

  • Thymodepressin;
  • Basiliximab;
  • Ustekinumab;
  • Efalizumab;
  • Alefacept;
  • Infliximab and many others.

Their action is very selective, in contrast to the hormonal principle of shooting sparrows from a cannon, but they are more expensive and are prescribed much less frequently due to many contraindications.

Cytostatics

Cytostatic agents inhibit the regeneration of the epidermis and very effectively destroy psoriasis in the early stages. At the same time, they are very aggressive, cause addiction and weaken the immune system. To correct the last point, immunomodulators are prescribed that increase the body's protective functions.

But they do this in a not entirely obvious way. To increase immunity, you must first act on it with a strong irritant and suppress it, as a result of which, after recovery, it will become stronger and stronger. This recovery can take from several months to six months, and during this time the patient will be susceptible to many infectious diseases.

Nonsteroidal drugs

Non-steroidal drugs relieve inflammation in areas where the skin is affected by psoriasis, but at the same time negatively affect the condition of the blood and organs of the digestive system.

External treatment

External treatment is safer and more effective in combating the symptoms of the disease, eliminating itching and burning. Traditionally, ointments, creams, tinctures based on tar, salicylic acid, and ichthyol, urea, and corticosteroids are used.

Tar is not very convenient to use, has an unpleasant odor and stains clothes, but is very useful in the fight against psoriasis.

Ointments containing vitamin D based on activated zinc are also very good. Often the products are produced in the form of aerosols and shampoos for the body and head. The most famous ointments - Advantan, Skin-cap, Elokom, Dithranol - have many positive reviews and are harmless, but they should only be used as prescribed by a doctor.

A group of vitamin A derivatives called “retinoids” are actively used in the treatment of psoriasis. They slow down the growth process of epidermal cells, which is very important for psoriasis (after all, skin disorders are observed precisely because cell division occurs at an impaired speed). In 10-15% of patients, complete disappearance of plaques is observed, in 50% there is an improvement in the condition of the skin.

Physiotherapy

Physiotherapy for psoriasis is recognized throughout the world. The most famous procedure, photochemotherapy (PUVA), combines irradiation with long ultraviolet rays with the intake of psoralens, substances with photosensitizing properties that increase the sensitivity of the skin to the effects of radiation. The course of treatment ranges from 20 to 40 daily procedures. Efficiency is achieved in over 90% of cases of therapy. But PUVA therapy has a significant disadvantage.

It is contraindicated in case of intolerance:

  • psoralens;
  • photosensitivity;
  • diseases of the digestive tract;
  • hearts;
  • diabetes mellitus;
  • tuberculosis;
  • pregnancy;
  • presence of tumors;
  • as well as people over 55 years of age and children.

Laser therapy

Laser therapy is also popular, as a type of ultraviolet irradiation using a gas laser. By mixing gases in the ultraviolet range, it is possible to obtain a narrow beam of light that is directed to the affected areas of the skin, providing a targeted effect. This slows down cell growth and relieves inflammation. This therapy allows for individual adjustment of the laser to the patient’s skin type and color, as well as the stage of psoriasis. The number of procedures is from 10 to 15, several times a week.

Innovative treatment methods include the excimer laser system, helium-neon and helium-cadmium lasers. The procedures help reduce plaques and relieve inflammation. The physiotherapeutic device for the treatment of psoriasis is a fluorescent erythema lamp. It can also be a quartz lamp for the treatment of psoriasis with a power of 60 W and arc bactericidal lamps.

It is also recommended to perform plasmapheresis, namely the removal of part of the plasma, cleansing it of harmful substances and returning blood cells back to the body in order to update its chemical composition. Up to 500 ml of blood can be extracted in one session. The number of sessions is determined by the doctor, but usually it is 4-5 procedures with an interval of several weeks. Thus, up to 30% of the total blood volume is cleansed and renewed. This helps to quickly get rid of the severe manifestations of psoriasis and allows you to achieve remission.

Alternative Methods

Other alternatives include visiting thermal spas, undergoing Garra rufa skin cleansing treatments, mud therapy or hydrotherapy. Unfortunately, psoriasis is a disease for which you need to be prepared for a long treatment. After all, no means have yet been invented that would most likely relieve the patient of all the unpleasant manifestations of the disease.

Do not forget that complex treatment includes diet, proper sleep patterns, and giving up bad habits. During pregnancy and lactation, it is quite difficult to choose a treatment method that is harmless to the fetus or child. Usually, herbal preparations are prescribed, for example milk thistle oil. It is applied to the skin in the form of compresses to relieve inflammation, heal wounds and relieve pain.

Folk remedies

Various folk remedies can be tested as background maintenance treatment. Their effectiveness has not been confirmed by traditional medicine, but has been tested for centuries.

Many generations of our ancestors saved themselves from annoying symptoms of the disease in these very ways:

Tar-based ointment is very effective:

  • 50 g tar;
  • 10 g fish oil;
  • 2 tbsp. Vaseline;
  • 2 tbsp. honey;
  • egg white;
  • 10 g boric acid;
  • Mix thoroughly and apply to damaged areas.

Boil flax seeds, burdock root and grape leaves in equal proportions in milk, strain and use as lotions.

Currently, there are various medications for psoriasis, the pharmaceutical effects of which are aimed at neutralizing the internal and visual symptoms of psoriasis.

To get the maximum effect in the treatment of psoriasis, completely different forms of medications are used (ointments, lotion, balm, creams, spray), however, it should be remembered that only an INTEGRATIVE APPROACH to the treatment of psoriasis can make the result as positive as possible!

Characteristics of drugs for psoriasis

Psoriasis is a chronic disease characterized by periodic remissions and exacerbations of the skin. There are a lot of medications for its treatment (ointments, tablets, sprays, etc.). Medications for psoriasis reduce skin flaking, itching, redness, and also reduce other negative manifestations on the body that cause discomfort to the patient.

When treating psoriatic manifestations on the skin, as a rule, the “staircase principle” is used, when external medications for mild psoriasis are first prescribed, and then (if they are ineffective) the patient is prescribed pills (including hormonal ones), etc.

If such therapy does not help to cope with the negative symptoms of psoriasis, then the most powerful treatment is used - immunosuppressants. Most often, such medications are prescribed for the development of psoriasis on the scalp. These drugs show maximum results in treatment, but it is important to remember that they have the greatest number of side effects.

Before starting drug therapy for psoriasis, you should consult with your doctor and perform a number of necessary examinations. This will allow you to determine the medications (tablets, ointments, etc.) that will be most effective IN EACH INDIVIDUAL CASE. It is quite possible that simply using the ointment will be enough to eliminate psoriatic manifestations on the elbows, head, knees, skin, etc. or cream to restore nail structure.

External medicines

External medications include:

  • cream;
  • hormonal and non-hormonal ointments;
  • gels (including for nails);
  • sprays;
  • adhesive plasters for skin;
  • natural oils;
  • shampoos;
  • sea ​​salt.

The prescription of a particular drug depends on the severity and severity of psoriatic symptoms on the skin.

CREAMS. This dosage form is considered most suitable for neutralizing skin diseases, especially on the legs and elbows. The components of skin creams are emuldigators, active substance, water and oils.

Creams containing vitamin D:

CALCIPOTHRIOL. This skin drug is an artificial analogue of vitamin D3, which can be combined with steroid drugs. Positive results of Calcipotriol are achieved when combined with UV skin treatment.

ACREEDERM CREAM. The drug has the following effects on the skin:

  • antiexudative;
  • anti-inflammatory;
  • antiallergic;
  • decongestant and antipruritic.

The active substance of the drug Akriderm is betamethasone dipropionate, which suppresses skin phagocytosis and reduces tissue permeability, which helps prevent the appearance of skin edema.

KREMGEN. Refers to combination medications against psoriasis, which effectively relieves skin from itching and allergies. When applied (on elbows, knees, soles of feet and other parts of the body), oxygen starvation of the skin is prevented.

The following skin products are no less popular:

  • Mesoderm, Uniderm;
  • Betaderm, Triderm, etc.

As a rule, CREAMS are prescribed to treat the initial stage of psoriasis, and for obvious symptoms of psoriasis, special OINTMENTS for the skin are most often prescribed.

OINTMENTS. External skin products in the form of ointments, which are prescribed against psoriasis, are divided into 2 groups:

  • non-hormonal;
  • hormonal.

Non-hormonal - have a mild effect on the patient, in contrast to hormonal treatment, which quickly relieves the symptoms of psoriasis on the skin. However, glucocorticosteroids can be addictive with long-term use, as well as many side effects.

1. Hormonal ointments. Glucocorticosteroid drugs contain various active substances on which their medicinal properties depend.

  • The group of medications for the development of psoriasis containing Mometasone (a glucocorticosteroid) includes: Avecort, Nasonex, Uniderm, Monovo, Elokom and Silcaren.
  • Betamethasone group: Betazon, Betasalik, Diprospan, Akriderm, Vipsogal and Flosteron.
  • Flumetasones: Locasalen, Locacorten, Lorinden, etc.

  • Ultralan series: Fluocortolone, Flunitsar, Sinaflan, Sinoderm.
  • Triamcinolone: ​​Kenacort, Fluorocort, Polcortolone, Ftoderm, Nazacort.
  • Hydrocortisones: Laticort, Hyoxysone, Sibicort and Oxycort, hydrocortisone ointment.
  • Clobetasol series: Dermovate, Cloveit, drug Pouecort, etc.
  • Budesonides: Apulein, Pulmicort suspension.
  • Triamcinolones: Berlicort, Kenalog, Nazarcort, Triacort and Fluorocort.
  • These drugs are used in the development of inflammatory processes.

The most effective medications for psoriasis are the FIRST 3 GROUPS of glucocorticosteroids.

Reviews from experts warn that the steroid drug should not be used for a long time, as this can cause atrophic changes in the skin. In addition, knowledge of the active substance included in the drug is especially important for patients with individual sensitivity to its components.

2. Non-hormonal ointments. The advantage of non-hormonal ointments in the fight against external manifestations of psoriasis is safety.

Most often used:

  • Zinc and Salicylic ointment;
  • Daivobet and Akrustal;

  • Kartalin and Belosalik.

However, it should be noted that non-hormonal medications for psoriasis have a much longer and weaker effect on skin problems.

GELS. There are several types of gels against psoriasis:

  • hormonal - Flucinar;
  • combined - Xamiol;
  • homeopathic - Psoril with tar;
  • with Panthenol - Bepanten;
  • antihistamines - Fenistil;
  • cosmetics with herbal ingredients - Zosterin, etc.

As a rule, gels are prescribed to neutralize the symptoms of psoriasis on exposed skin areas (elbows, hands, etc.).

Gel remedies for psoriasis are prescribed for use when:

  • vulgar skin psoriasis;
  • pustular form of psoriasis;
  • for psoriasis of the scalp;

  • nail psoriasis;
  • articular forms of psoriasis.

The therapeutic effect of the gels is explained by the enveloping of the affected areas of the skin with a gel base, which has a beneficial effect on the patient’s skin.

SPRAYS. These remedies are prescribed for the regular treatment of psoriatic rashes on the body and are most effective during remission of psoriasis. Despite the fact that the sprays do not contain steroid components, they have a good antipsoriatic effect.

Most often prescribed:

  • Skin-Cap (suppresses fungal growth, especially on the scalp);
  • Spray 999 (prescribed for the treatment of psoriatic plaques on the body).

An aerosol medication for psoriasis is convenient because it does not leave behind a greasy sheen or traces of use on clothing.

OILS. Oils are widely used in conjunction with medications in the treatment of psoriatic skin manifestations. This direction in the treatment of psoriasis is not new. Since ancient times, traditional healers have used natural oils as a therapeutic effect on the skin.

During periods of exacerbation, 2 groups of oils are used against psoriasis:

1. Essential: bergamot, oregano, jasmine, chamomile, cedar, lavender, tea tree, cumin, mint.

These oils are most often prescribed as part of a general complex of antipsoriatic therapy.

2. Food. Edible oils can help treat psoriatic symptoms at home because they effectively eliminate the inflammatory process, relieve skin irritation and accelerate regenerative processes.

These oils include: olive, linseed, burdock.

Most often, burdock and olive oil are used at home for lesions of the scalp, as they help improve blood circulation and restore damaged hair follicles.

SHAMPOOS. In addition to oils, shampoos are of great importance in the complex treatment of psoriasis of the scalp. In this case, both traditional (with the addition of tar) shampoos and new medications can be used.

Types of shampoos:

  • Tar. They contain tar (from juniper, birch and pine). The tar group of shampoos includes Tana, Algopix, 911 tar, Friederm Tar. Such shampoos effectively neutralize itching on the head.
  • Antifungal. These shampoos additionally contain antimycotic components. The active component of these medications is ketoconazole. The most popular ones include Vichy, Keto Plus, Nizoral, Bioderma, Squafan. The disadvantages of shampoos include the possibility of increased itching during the first uses.
  • Medicinal. These include shampoos with salicylic, urea, ichthyol and zinc, which have an antimycotic effect. This category includes Libriderm, Etrivex, Skin-Cap.

  • Cosmetic. Such shampoos have a healing effect on the affected area of ​​the scalp, preventing dryness. Effective cosmetic shampoos include Sulsena, Natura and Friederm Balance.
  • Children's. Due to the fact that shampoos for children against psoriatic manifestations do not contain various chemical additives, they are ideal means of treatment. The most popular are Nipp and Baby Johnsons.

Using sea salt

Salt has a positive effect, having a healing effect on all parts of the body. A good effect of using salt is observed for psoriatic symptoms of nails and damage to joints on the hands and feet.

Salt is used in the form of medicinal baths (1 kg per 2 liters of boiling water), which are taken for no more than 20 minutes 3 r. within 7 days. The saline solution has a relaxing effect on the patient's body, accelerates regenerative processes, improves the structure of the nails and neutralizes psoriatic manifestations in the joint area.

It should be remembered that even such a seemingly safe remedy as salt may have restrictions for use in cases of hypertension and heart disease.

Therapeutic plasters

The composition of the medicinal patches includes oils (camphor and eucalyptus), methyl salicylates, fluocionide, borneol. Adhesive plasters are designed to remove psoriatic plaques (especially on the elbows) at home. They have a regenerating, anti-inflammatory and anti-allergic effect on the patient's body. According to experts, it was patches against psoriasis that were in greatest demand among patients in 2015-2016.

New products (“Tender Skin” and “Quiannaide Xinmeisu Tegao”) used in the complex treatment of skin psoriasis are called “plaque killers” in medical practice because they suppress the activity of epidermal cells.

Oral medications

Medicines for oral use, as a rule, are prescribed only in complex therapy of the disease.

Such medications are divided into groups:

  • antihistamines;
  • homeopathic
  • antibiotics;
  • enterosorbents;
  • immunosuppressants;
  • vitamin preparations.

Each group of drugs against psoriasis is characterized by certain effects on the patient’s body.

I. HOMEOPATHIC MEDICINES. Homeopathic remedies are widely used against psoriasis.

The list of medications includes:

  • Psoriaten (ointment) and Psorinohel - prescribed orally for all forms of psoriasis;
  • Formicum acidum - prescribed for serious complications in all parts of the body (elbows, knees, etc.);
  • Album arsenicum - the drug is effective for profuse, fine-plate peeling of the skin;
  • Yodatum arsenicum - prescribed to weakened and elderly patients;

  • Hydrocolite - a drug prescribed to get rid of severe flaking on the body;
  • Carbonica calcarea - used for the hardening of psoriatic plaques on the skin and nail fungus;
  • Manganum - prescribed for the treatment of joints on the elbows and knees;
  • Petroleum is a drug that restores the structure of nails well.

Homeopathic medicines are selected individually, based on the patient’s condition - this is the main condition for the effectiveness of homeopathy.

II. ANTIHISTAMINES. This pharmacological group is prescribed for severe itching, swelling of the skin and allergic reactions.

These include:

  • Claritin, Diazolin;
  • Zirtek, Suprastin;
  • Loratadine, Erius, etc.

In addition to the antipruritic effect, antihistamines can have a mild sedative effect, normalizing the patient's sleep.

III. HEPATOPROTECTORS. They can be prescribed to a patient with concomitant complications of psoriasis in the form of gastrointestinal disorders.

The most popular hepatoprotectors are:

  • Essentiale and Likopid tablets;

  • medicine Karsil and Silimar.

The drug Likopid deserves special attention, which, in addition to its hepatoprotective properties, has an immunomodulatory effect, making it stand out from all drugs in this group.

IV. ANTIBIOTICS. Prescribed for the development of psoriasis, in extreme cases, when psoriasis is complicated by the acute development of infectious processes.

Your doctor may prescribe the following antibiotics:

  • Penicillin series (Amoxicillin);
  • Macrolide (Erythromycin);
  • Cephalosporin (Cefazolin).

It is important to consider that any form of antibiotics is prescribed after medical consultation.

V. VITAMIN COMPLEXES. Vitamins and microelements are present in the body of every person. They help restore the functionality of the immune system and contribute to the overall health of the body.

The following vitamin complexes are suitable for getting rid of psoriasis:

  • Decamevit and Complivit;
  • Undevit, Gegsavit and Revit.

In addition, vitamin preparations of groups E and A, which are included in Aevit, are prescribed for mandatory consumption. In its own form, vitamin A is included in Retinol, and E is included in Alpha-tocopherol. Vitamin complexes have a positive effect on lipid metabolism, improvement of nail structure, and metabolic processes. A course of vitamin therapy is recommended 2 times a year.

VI. SORBENTS. When neutralizing psoriasis, the timely removal of toxic substances from the patient’s body, which most often accumulate in the gastrointestinal tract, is of no small importance.

To quickly remove toxins in psoriasis, enterosorbents (Activated Carbon tablets, Enterosgel, Polysorb and Polypefan tablets) are prescribed.

The use of these medications for psoriasis is prescribed not only for exacerbations, but also in complex therapy.

VII. IMMUNOSUPPRESSORS (cytostatics). The effective action of these drugs depends on the cytostatic effect on the cellular composition of the lymphoid system. The most well-known immunosuppressant is Methotrexate. However, its use is limited by high toxicity and many side effects (hepatitis, headache, vomiting, kidney failure, etc.).

Sandimmune (Cyclosporin-A) is considered a more gentle immunosuppressant. Sandimmune therapy is carried out only in a hospital setting for 6-7 weeks. If the patient tolerates this therapy well, the course is repeated 2 times. in year.

To improve cellular respiration and general detoxification of the body, an infusion solution of Reamberin, the active component of which is succinic acid, can be prescribed.

Despite the conflicting opinions of experts, one of the most effective medications for psoriasis from the group of antistatic agents is the long-acting hormonal drug Diprospan. Its effectiveness is explained by the active components, but due to the severe consequences, Diprospan is prescribed only against forms such as psoriatic arthritis, erythroderma and pustular psoriasis.

Genetically engineered biological products

The newest drugs for psoriasis with targeted effects (Secukinumab, Ixekizumab, Netakimab). They very selectively block key steps in the development of the disease and are considered targeted drugs. In the case of IL-17 inhibitors, only IL-17a is blocked, without affecting other immune processes in the body. Genetically engineered biological drugs (GEBP) are prescribed for:

  • severe form of psoriasis;
  • moderate form of psoriasis;
  • nail damage;
  • joint damage;
  • psoriasis of problematic localizations;
  • pronounced deterioration in quality of life.

Genetically engineered biological drugs are effective in treating psoriasis, but they require long-term, ongoing treatment. Provided there is a clear schedule for using such medications, psoriasis goes into stable remission and, as long as the patient follows these rules, the disease does not return.

Biological drugs for psoriasis

Biological medications (Enbrel, Remicade) are used for severe forms of psoriasis. Biological drugs are administered by infusion and block the negative reaction of the immune system.

Biological methods of therapy are used quite rarely and show good results, but their cost is very high, which prevents mass use.

In addition, the possibility of negative manifestations has not been fully studied, and many scientists believe that such medications for psoriasis may increase the risk of developing malignant skin tumors.

Traditional methods of treating psoriasis

Folk remedies were used long before the advent of traditional medicine. For a long time, psoriasis was considered a “cursed” disease and healers treated it secretly, at home, in the strictest secrecy. And even now, despite well-developed medicine, folk recipes have not lost their relevance, primarily because such methods of treatment are due to the effect of medicinal herbs.

The following recipes are used to get rid of psoriasis:

  • at home you can prepare a warm bath with celandine. To do this you need to take 3 tbsp. ground celandine and fill them with 0.5 liters. boiling water, then strain and add to the water prepared for bathing;
  • very often, folk healers use a mixture of Kalanchoe juice (10 g), honey (10 g) and eucalyptus oil (30 g). All ingredients are mixed and the resulting solution is applied to the skin 2-3 times a day;
  • For psoriasis of the elbows and palmar-plantar form, you can use kombucha at home to relieve the inflammatory process on the skin. To do this, immerse your hands or feet in a solution with kombucha 1 hour before bed for 30-40 seconds, and then wait (without wiping) until they dry themselves;

  • For oral use at home, you can prepare a decoction of bay leaves. For this purpose 20 gr. Broken bay leaves are brewed 2 tbsp. boiling water for 10 minutes, after which the solution is filtered and taken 3 times a day, ½ tbsp. in a week;
  • at home, a decoction of burdock and dandelion roots (1 tbsp each), poured into 1 tbsp, is effective against psoriasis. boiling water and kept on fire for 7-10 minutes. After straining, it is recommended to take 100 ml of the decoction warm. 3 r. in a day.

Despite the fact that traditional methods of getting rid of psoriasis are considered safe, before using them, you should consult with your doctor.

Psoriasis drugs from China

2015 - 2016 are characterized by the great popularity of drugs from China to neutralize psoriatic symptoms on the skin, which corresponds to all modern achievements in pharmacology. Chinese doctors are famous for their approach to treating diseases, which is primarily aimed at activating the body's resources. Today, many medications from China are used for psoriasis.

The best ones:

OINTMENT “KING OF SKIN”. This drug from China contains ket oko nazol and clobetasol propionate, and additional components of the drug for the development of psoriasis are ingredients of plant origin (kachari, turmeric, sandalwood, etc.).

The drug (ointment) from China has anti-inflammatory, immunosuppressive and antiallergic effects. It is recommended for use against moderate psoriatic manifestations and fungal nail infections.

"PSORIASIS CREAM". The composition of the medicinal cream includes components such as sophora, pearl powder and osthol. This drug from China has a calming and anti-inflammatory effect, relieving skin irritations, including psoriatic manifestations on the hands and feet. The maximum effectiveness of the drug is observed with continuous use for 7 days. In addition, the advantage of drugs in this group is their ability to be used on the skin at home.

LOTION "FUFAN". One of the most popular drugs from China today. It contains acids (salicylic and fluoric), as well as borneol.

Salicylic acid prevents the development of mycoses, including the nail area. Fluoric acid neutralizes the pathological process on the skin. Borneol has a cooling and analgesic effect on psoriasis-affected skin.

In addition, “Fufan” promotes rapid regeneration of skin tissue and improves local immunity. The lotion can be used on the entire body, as well as on the scalp. “Fufan” softens the keratinized parts of the skin well, is absorbed as much as possible, without leaving marks on clothes.

“Fufan” helps normalize blood circulation in the affected part of the body, preventing secondary infection of the skin, and can be used at home.

It is important to consider that Fufan cannot be used on large areas of the skin, and you should also avoid getting the lotion on the mucous membranes and wound surface, because Fufan can prolong the healing time of a skin wound.

"XIAOYIN" TABLETS. Chinese tablets consist of parsnip, sophora, angelica, noricum, peony and honeysuckle. The pharmacological properties of the drug are determined by the combined effect of herbal preparations on the skin.

Tablets are recommended to be taken as part of complex therapy, as they have a weak therapeutic effect against psoriatic manifestations on the skin. "Xiaoyin" has no side effects and can be taken even by children.

The peculiarity of antipsoriatic drugs for getting rid of psoriasis from China is their natural composition and the complete absence of chemicals. As a rule, they have a minimum number of contraindications and side effects, which makes psoriasis therapy as safe as possible.

It must be borne in mind that all medicines, including Chinese drugs, should not be used without first consulting a doctor. Only a highly qualified specialist can find out which medications are suitable for the patient, taking into account the characteristics of the body and the course of psoriasis.

A new biological drug has appeared in Russia for the treatment of moderate and severe forms of plaque psoriasis - C® (ustekinumab), which combines a unique safety profile comparable to placebo and ease of use: subcutaneous injections once every 12 weeks. The drug, which is a 100% monoclonal human antibody, opens a new class of drugs for the treatment of psoriasis.

Currently, psoriasis is one of the most common chronic dermatoses, affecting about 125 million people worldwide. Scientists believe that a key role in the development of psoriasis is played by disturbances in the immune response (the inflammatory psoriatic process is of an immune nature with impaired T-cell function). Patients with psoriasis experience significant physical and psychological discomfort, they have great difficulties with social and professional adaptation.

According to the European Psoriasis Patients' Association (EUROPSO) study of nearly 18,000 psoriasis patients, 77% reported dissatisfaction with available treatments, despite being generally satisfied with their doctors. Patients consider the most difficult aspects of treatment to be its labor intensity (50%) (the need to take medications daily and use local therapy - ointments, creams), as well as ineffectiveness (32%).

A breakthrough in the treatment of psoriasis are biological drugs that block the action of certain cells of the immune system that play a key role in the development of the disease. Biological therapy makes it possible to achieve the main therapeutic goal - long-term remission and complete cleansing of the skin from the manifestations of psoriasis.

The biological drug STELARA® has a highly selective mechanism of action that affects the cytokines interleukin-12 (IL-12) and interleukin-23 (IL-23) - proteins that play a key role in the development of psoriasis.

Thus, acting at an earlier stage of inflammation, the drug provides a quick and lasting effect. Improvements become noticeable to the patient (according to subjective sensations) already 2 weeks after the 1st injection. Effectiveness is maintained over a long period of time, with maintenance therapy every 12 weeks. Unlike other biological drugs, it has a unique molecule composition, which is 100% monoclonal human antibodies, which are perceived by the body as its own immunoglobulin.

This provides an optimal safety profile comparable to placebo and a low incidence of adverse events compared to other biological drugs for the treatment of psoriasis. The efficacy, safety and tolerability of STELAR® in the treatment of moderate to severe forms of plaque psoriasis were studied in 1996 patients in 2 multicenter, randomized, placebo-controlled, double-blind phase III clinical trials PHOENIX 1 and PHOENIX 2.

Research data indicate the achievement of a PASI index of 75 in patients receiving STELARA® (skin clearing by 75% compared to the initial state) at week 12 (after 2 injections), which persisted for at least one year with maintenance therapy every 12 weeks.

“Modern healthcare in Russia is actively pursuing organizational reforms aimed at improving the quality of life of the population, which is directly related to improving the quality and efficiency of medical care,” comments Academician Kubanova A.A., Director of the Federal State Institution State Scientific Center for Diagnostics, Chief Dermatovenereologist and Cosmetologist of the Russian Federation, “Particular attention is focused on the development of high-tech care using biological drugs for the treatment of severe forms of psoriasis. This highly effective method makes it possible for the first time to achieve long-term remission in the treatment of this complex autoimmune disease, which has a chronic relapsing and torpid nature.” This innovative approach to the treatment of psoriasis opens up good prospects for its widespread implementation in medical practice. STELARA® is also currently being studied for the treatment of psoriatic arthritis, Crohn's disease and sarcoidosis.
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