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The drug Ibuklin is a representative of the NSAID (non-steroidal anti-inflammatory drugs) group of medications. Medicines in this category have antipyretic, anti-inflammatory and analgesic properties.
The term "non-steroidal" means lack of a hormonal basis in the preparations. Their action is aimed at blocking chemicals that provoke pain.
How to replace Ibuklin: instructions for use, prices, reviews of cheap analogues, read below.
Active ingredients are ibuprofen (non-steroid) and paracetamol (painkiller and antipyretic component). Additional ingredients: starch, glycerol (trihydric alcohol), cellulose, talc, silicon dioxide, magnesium stearate.
The combined effect of the two main components reduces inflammation, relieving symptoms of fever, reducing pain.
Ibuklin and its analogues are widely used to treat inflammatory processes in the joints. The components of the drug are active against arthralgia (painful joint changes).
The maximum concentration of the drug in the body is reached after an hour and a half.
For heart disease and diabetes, the medication is prescribed with caution.
During treatment with Ibuklin and its analogues, alcoholic beverages are not allowed.
Prescribing a non-steroidal drug during pregnancy it is highly undesirable.
Ibuklin is produced in tablet form. Children's version (Ibuklin Junior) - soluble tablets with mint flavor. For the treatment of children, the drug is used from 3 years to 12 years of age.
For adults, the standard dosage is one tablet per dose. You are allowed to take no more than three tablets within 24 hours. In this case, the range between doses should be 4 hours or more.
The children's dosage of the drug is calculated in proportion to the child's weight: from 11 to 15 kg - one soluble tablet at 8-hour intervals, 16-21 kg - 1 tablet. at 6-hour intervals, 22-40 kg – 2 tablets every 8 hours.
Ibuklin is manufactured by Dr. Reddy's Laboratories Ltd. Hyderabad, Andhra Pradesh, (India). The cost of both children's and adult drugs is about 100 rubles.
Drugs replacing Ibuklin are produced in Russia and abroad. The active ingredients of inexpensive analogues in tablets are ibuprofen and paracetamol.
Indications and contraindications for use of substitutes correspond to the original. The drugs differ in price, manufacturer and recommended dosage.
A list of Ibuklin analogs that can be purchased cheaper is presented in the table.
Analogue | Dosage | Manufacturer | Price |
---|---|---|---|
Khairumat | Three times a day after meals, one tablet. In severe cases, the dose is doubled. | Highglance Laboratories Pvt. Ltd. (India) | 140 rub. |
Nurofen Long | One tablet after the main meal. The interval between doses is 6 hours | Reckitt Benckiser Healthcare International Ltd (UK) | 190 rub. |
Next | Adults take one tablet three times, children over 12 years old take no more than 2 tablets. | Pharmstandard-Tomskkhimpharm OJSC (Russia) | 130 rub. |
Ibuprom | Per tablet with a range interval - at least 6 hours | US Pharmacia Sp.zo.o (Poland) | 86 rub. |
Brustan | Adults – one tablet 4 times a day | Ranbaxy Laboratories, Ltd. (India) | 110rub |
Replacement therapy can be carried out with medications whose composition is based on a combination of paracetamol and diclofenac. The most common are Dolaren and Panoxen.
Medicines are prescribed to treat inflammatory processes in joints and muscles, neuralgia, toothache and headaches. To relieve cold symptoms, such a replacement for Ibuklin is not recommended.
The decision to replace the original with an analogue is made by the doctor!
Ibuklin and its substitutes are quite aggressive medications, the use of which may cause the following side effects:
If sudden side effects occur, you should consult a doctor to change the medication.
What is the drug “Ibuklin” prescribed for? You will find a comprehensive answer to the question posed below. Moreover, we will tell you what the composition of this drug is, how it should be taken and in what dosages.
What is the drug “Ibuklin”, what is this drug taken for, and how often is it prescribed by doctors? This drug is a combined synthetic drug that has analgesic, antipyretic, and anti-inflammatory effects on the body.
The medication "Ibuklin" (doctors' reviews of this drug are mostly positive) is available in the form of:
How does the drug "Ibuklin" work? The instructions for use of this medicine state that its active ingredients are able to regulate the development of inflammation in the lesion, as well as provide analgesic, anti-inflammatory and antipyretic effects.
It should be noted that this medication affects the joints, significantly reducing their morning stiffness and swelling. A component such as paracetamol begins to act within 7-10 minutes after ingestion, and reaches its maximum effect after about an hour. As for ibuprofen, it is absorbed a little more slowly. Its maximum absorption is achieved after approximately 2.5-3 hours. Such a drug has a longer lasting effect than the components presented on their own. That is why doctors quite often prescribe the drug “Ibuklin” to their patients. The indications for this medicine include a huge number of different abnormalities. Let's look at them in more detail.
This drug is indicated for moderate or mild pain of various origins, namely:
What is the medicine “Ibuklin” prescribed for by doctors? In addition to eliminating pain of various etiologies, this drug is indicated for the treatment of the following disorders:
Now you know what Ibuklin is and what this drug helps with. However, such a drug has not only many indications, but also a large number of contraindications. According to the instructions, the presented medication is not recommended for use if:
This drug should be taken with extreme caution and only under medical supervision when:
Among other things, this drug is prescribed with extreme caution in case of allergic reactions to acetylsalicylic acid or other non-steroidal anti-inflammatory drugs, as well as during the simultaneous use of oral anticoagulants.
Dispersible tablets intended for children under 12 years of age are prescribed at the rate of 20 mg per 1 kg of child weight per day. The indicated dose can be divided into 2 or 3 doses.
How should I take Ibuklin? The dosage for adults and adolescents over 12 years of age is 1 or 2 tablets twice or thrice a day. It should be especially noted that you should not take more than six tablets per day.
What nuances should be considered before using the drugs “Ibuklin” and “Ibuklin Junior”? Dosage for children and adults should only be prescribed by an experienced specialist based on diagnosis. This medicine should only be taken orally. It is recommended to do this before a meal or 120-180 minutes after it. For elderly people, as well as patients with liver or kidney problems, it is advisable to reduce the daily dose. In this case, the interval between taking tablets should be increased to 8 hours.
According to the instructions, the drug "Ibuklin" can cause many side effects, namely:
If you experience at least one of the above side effects, you should reduce the dosage or stop taking the drug altogether.
Ibuklin is a typical member of a group of drugs called non-steroidal anti-inflammatory drugs. According to the international classification, the drug belongs to anti-inflammatory and antirheumatic drugs, which are derivatives of ibuprofen and its combinations.
M01AE51 Ibuprofen in combination with other drugs
Ibuprofen
Paracetamol
Non-narcotic analgesics, including non-steroidal and other anti-inflammatory drugs
Analgesic (non-narcotic) drugs
Anti-inflammatory drugs
Thanks to its complex composition, the drug has a wide range of effects, which ensures its use in many areas of medicine.
Thus, indications for the use of Ibuklin include severe hyperthermia, and the fever may have a different genesis of origin. These can be either colds or more serious infectious diseases with severe inflammation.
Ibuklin copes well with pain, but its degree should not be excessively great. The drug relieves the average intensity of pain in the presence of an inflammatory focus in the bones, joints and muscles, for example, with gouty or rheumatoid arthritis, ankylosing spondylitis.
Indications for the use of Ibuklin in the fight against pain include degenerative processes in joints and bone structures with deforming osteoarthritis and osteochondrosis.
The drug is effective for tendovaginitis and bursitis, when the periarticular capsule is involved in the process. Lumbago, neuralgia, muscle pain, as well as post-traumatic injuries from dislocations, sprains, fractures and bruises are also grounds for the use of Ibuklin.
The main characteristics of this pharmaceutical product are its release form, which is represented by a tablet preparation, as well as its physicochemical properties. They involve coating each tablet with a film coating, the shade of which varies from light orange to a more saturated color.
It is also worth highlighting the capsule-like shape, which has a dividing strip on one side and a smooth surface on the other.
The release form in the form of tablets determines the packaging of the drug. So, Ibuklin comes with 10 tablets in one blister, which corresponds to one cardboard package.
Each tablet contains 400 mg ibuprofen and 323 mg paracetamol. In addition to the main components, there are several additional ones, for example, cellulose, starch, glycerin and others.
The tablet form is very convenient to use, since thanks to the specific composition of each tablet, you can strictly monitor the dose and avoid overdose.
Pharmacodynamic properties are determined by the main components of the drug - ibuprofen and paracetamol.
Each of the above components has certain capabilities, which in combination with another component provides a pronounced therapeutic effect.
The pharmacodynamics of Ibuklin is a complex of actions of both drugs, which have an analgesic and anti-inflammatory effect. By blocking cyclooxygenases, the drug not only reduces the manifestations of the inflammatory reaction, but also acts as an antipyretic.
As for paracetamol, it is not capable of providing a pronounced anti-inflammatory effect on its own, since its activity is inhibited by peroxidases. As a result, Ibuklin additionally contains ibuprofen to enhance the therapeutic effect.
The components of the drug, having a combined effect, provide a reduction in pain in the joints, which in turn leads to a decrease in stiffness in motor activity and returns the previous mobility of the joint.
The complex drug consists of two main active drugs, therefore the pharmacokinetics of Ibuklin is based on the combined action of both components.
Thus, ibuprofen quickly penetrates into the general bloodstream through the mucous membrane of the digestive organs after oral use. Within a couple of hours its maximum concentration in plasma is observed.
Almost 99% of ibuprofen binds to plasma proteins, with which it is carried through the bloodstream. Excretion of ibuprofen is carried out by filtration by the kidneys in unchanged form or in the form of oxidized metabolites in an inactive form.
In the above ways, all ibuprofen metabolites are eliminated from the body within 24 hours, and after 24 hours the person completely gets rid of the drug.
The pharmacokinetics of Ibuklin, which contains paracetamol, is due to good absorption. Half an hour after taking the tableted drug orally, the concentration of paracetamol in the bloodstream reaches its maximum value. This level remains for 4 hours and gradually begins to decrease.
As for the connection with blood proteins, paracetamol is transported in combination with them only in a partial amount (approximately 25%). After 1.5-2 hours, only half of the taken dosage remains in the human body. Metabolism occurs in the liver with the formation of glucuronides and sulfates. Paracetamol is excreted by the kidneys, gradually decreasing the concentration in the blood and increasing in the urine.
Throughout the entire period of pregnancy and after childbirth, when the baby is breastfed, any medication should be taken under the supervision of a doctor. This is due to the high probability of the drug reaching the child.
The use of Ibuklin during pregnancy is permitted if the benefit to the expectant mother is significantly greater than the harm to the fetus. During the experiments, it was concluded that Ibuklin is not capable of exerting a mutagenic or teratogenic effect.
You need to use medications especially carefully in the first trimester of pregnancy, when gradual development of fetal organs is observed. Subsequently, their formation and development occurs.
The use of Ibuklin during pregnancy usually does not cause harm to the woman and the fetus, however, it is necessary to strictly control the dosage and duration of use of the drug to avoid negative effects on the fetus.
In order for the drug to have a therapeutic effect without the occurrence of adverse reactions and aggravation of the condition, it is necessary to know the contraindications to the use of Ibuklin.
These include the age of children under 12 years old, the individual characteristics of the body, when responses to the administration of a certain medicinal component are genetically determined. Also, contraindications to the use of Ibuklin include the presence of ulcerative defects in the mucous membrane of the digestive organs and bleeding in the acute phase.
It is not recommended to take Ibuklin in case of renal failure in the stage of decompensation, with combined pathology of the paranasal sinuses with bronchial asthma, polyposis and an allergic reaction to acetylsalicylic acid.
In addition, Ibuklin is not advisable for use in cases of damage to the optic nerve, pathology of the circulatory system, in the early period after coronary artery bypass surgery, as well as in cases of severe liver pathology, inflammatory bowel diseases and an increased amount of potassium in the blood.
In addition to absolute ones, there are also relative contraindications, which include metabolic pathologies, heart diseases, vascular disorders, simultaneous use of hormones, anticoagulants, antiplatelet agents and NSAIDs.
Monitoring is necessary when taking Ibuklin over a long period of time.
The main side effects of Ibuklin, as in many other cases of taking medications, are allergic reactions. They may manifest themselves in connection with the individual characteristics of the body’s immunity. As a result, oral administration of the drug may result in a powerful immune system response, manifested by various clinical symptoms.
Most often, you can observe a rash of various diameters and shapes, tingling sensations, itching, up to the development of urticaria and Quincke's edema. In addition, manifestations include pain in the stomach and abdomen, nausea, slight dizziness, vomiting, headache and visual impairment.
Side effects of Ibuklin may also relate to impaired renal function, the appearance of erosive damage to the mucous membrane of the digestive organs and changes in the blood picture with a decrease in the number of platelets, red blood cells, changes in the size of blood cells, hyperkalemia, hyperuricuria and azotemia.
If pain occurs in the stomach and vomiting, it is necessary to monitor the color of the vomit. If it resembles “coffee grounds,” then you need to urgently call an ambulance. These symptoms signal the onset of gastric bleeding.
In addition, bleeding from the intestines is indicated by the appearance of blood in the stool (the so-called melena). This condition also requires immediate medical intervention.
The tablet form of the drug involves taking it orally a couple of hours before or after meals. The tablet should not be chewed and should not be swallowed whole with a few sips of water.
The method of administration and dosage of medications are selected individually, taking into account the degree of illness, age and health status of the person.
Since children under 12 years of age do not have permission to take this drug, at an older age adults can use it, 1 tablet up to 3 times a day. It is necessary to maintain a certain interval between taking the medication, which should not be less than 4 hours.
Please note that a single dose of the tableted drug Ibuklin is a maximum of 2 tablets, and for a daily dosage - a maximum of 6 tablets.
The method of administration and dosage should be adjusted in elderly people, as well as in the presence of severe concomitant pathology. So, their break between doses of the drug should not be less than 8 hours.
Without medical supervision, the use of Ibuklin as an antipyretic drug is approximately 3 days, and as an analgesic drug - no more than 5 days.
If the drug Ibuklin needs to be taken for a long time, then the functioning of the liver, kidneys and the state of the circulatory system should be monitored using laboratory research methods.
If the dosage and duration of administration are not observed, the likelihood of an overdose increases. In this case, certain nonspecific symptoms may suggest an accumulation effect of the drug and an increase in its side effects.
An overdose of Ibuklin can manifest itself in the form of digestive disorders with nausea, vomiting and pain in the epigastric zone. Clinical signs of hepatotoxic syndrome, disturbances of consciousness, headache, decreased blood pressure and pallor of the skin are also possible.
If such symptoms are observed, it is necessary to carry out some procedures that will remove metabolites and drug residues.
So, you first need to rinse the stomach so that part of the drug that has not yet been absorbed can be eliminated from the body. In addition, it is necessary to take activated carbon, which is a sorbent. It will also help block further entry of the drug into the bloodstream.
Overdose in some cases requires hemodialysis and monitoring of the blood picture. If the balance of electrolytes is disturbed, the deficiency should be replenished and the indicators returned to normal.
People who abuse alcoholic beverages should not use Ibuklin at the same time due to the fact that the likelihood of liver damage increases.
The interaction of Ibuklin with other drugs, for example, those affecting the coagulation circulatory system, is undesirable, as the risk of erosive damage to the mucous membrane of the digestive tract and the development of bleeding increases.
Ibuklin can be bought without a prescription at any pharmacy. The drug is a combination drug: it has anti-inflammatory, analgesic and antipyretic (antipyretic) effects on the patient’s body. The triple effect is due to the interaction of two of the safest painkillers and antipyretic non-steroidal anti-inflammatory drugs - the well-known paracetamol and ibuprofen.
Paracetamol and ibuprofen are not only unconditionally compatible, but also complement each other. They are approximately the same in terms of effectiveness and safety. Only paracetamol has an insignificant anti-inflammatory effect, unlike ibuprofen, which is a much better pain reliever (the analgesic effect begins already at a dose of 5 mg/kg of body weight).
Paracetamolum is absorbed somewhat faster, but ibuprofen has a longer effect. Ibuprofen is concentrated more in the synovium of the joints than in the blood; paracetamol is distributed more evenly in body fluids. These features determine the list of indications for the use of the drug.
Although the components of the drug have an anti-inflammatory effect, the question: “Is Ibuklin an antibiotic or not?” is completely incorrect. Of course, this medicine is not an antibiotic, since it is not an etiotropic drug, but a pathogenetic one, that is, it relieves only symptoms: fever and pain.
Numerous tests and studies have shown that ibuprofen and paracetamol, of all similar analgesics-antipyretics, differ for the better in terms of the number of side effects. Of course, this is especially important when treating children.
Ibuklin is produced in two types:
1. In adult dosage (0.4 g ibuprofen, 0.325 g paracetamol). It looks like capsules in an orange shell, sometimes marbled in color, separated on one side by a line. Recommended only after 12 years.
2. “Junior” ibuklin for children - a pink round tablet with the smell of mint and fruit. In addition to auxiliary components, it contains 0.1 g of ibuprofen and 0.125 g of Paracetamolum. Indicated for children over 3 years old. It has the property of being easily and quickly dispersed in liquids, which makes it easier to take.
If we analyze why ibuklin is prescribed, it is clearly seen that the treatment is symptomatic and has an indirect effect on the disease itself.
Contraindications:
Side effects:
Ibuklin can cause:
The medicine can be used for no longer than 5 days as an analgesic and no longer than 3 days as an antipyretic.
In the practice of doctors, there are cases where a significant excess of just a dose of paracetamol for several days caused fulminant liver failure in a child. The hepatoxic effect of ibuklin when the dosage is exceeded can be quite high in adults. Therefore, in some countries, drugs combining paracetamol and ibuprofen are sold only with a doctor's prescription.
It is necessary to ensure that ibuclin is not used together (or the use is under the supervision of a doctor):
Ibuklin can affect a person's concentration and ability to react quickly. Therefore, for the period of treatment you need to stop operating machinery and vehicles.
1. Ibuklin for adults is taken without chewing, 2 hours after meals. Maximum daily dosage: 3 tablets per day. Adolescents over 12 years old - 2 tablets per day.
2. If you take ibuklin for children, the instructions for use suggest a dosage depending on weight/age:
Children's effervescent tablet ibuklin is dissolved in 1 tsp. (5 ml) cooled boiled water. This form is convenient for babies who are difficult to persuade to swallow hard capsules.
Attentive parents should know that to relieve high fever, they should still use single-component drugs, and consult a doctor before using ibuklin.
Anti-inflammatory non-steroidal drugs are in great demand among people of all ages: they can work as an antipyretic and analgesic, or only alleviate the inflammatory process.
A particularly well-known substance in this category is ibuprofen and a drug based on it, which is often used to relieve migraines. How does the combined drug Ibuklin differ from it, what does this medication help with?
We are talking about ibuprofen for a reason - Ibuklin is a derivative of the tandem of ibuprofen and paracetamol that are already familiar to everyone. The latter substance is also well known, especially to young parents, because doctors often prescribe the medicine of the same name as an antipyretic for children. What happened after combining these components?
Due to the fact that Ibuklin is a combination drug, doctors can prescribe it for several purposes that do not intersect with each other. At the same time, for adults and children, the indications for the use of Ibuklin are approximately the same. This is mainly:
However, you need to clearly understand what Ibuklin tablets help with in the latter situation - they will not eliminate the infection and will not shorten the duration of the disease: the drug will only remove the symptoms or reduce their severity. For this reason, Ibuklin during ARVI is used only as an element of complex therapy.
At the same time, doctors insist that every consumer understands that Ibuklin is a drug that affects only symptoms: this is more pronounced with flu and colds, however, even in the case of pain in the musculoskeletal system, it is not aimed at treatment, although it can eliminate inflammatory process. Therefore, you should not abuse this medication - by constantly relieving unpleasant sensations, you may miss the serious development of the disease.
This drug can be used without medical advice, but pediatric therapy is still recommended to be carried out under the supervision of a doctor. In adults, the dose is taken before meals, or after it, but after 1.5-2 hours, because a full stomach will interfere with the absorption of the active components and, accordingly, will make taking the drug completely useless or significantly reduce its effectiveness.
At the same time, it is desirable that the conditional age limit be observed - children under 6 years old should not be given more than 3 tablets per day.
Ibuklin is taken as an analgesic for no longer than 5 days, and as an antipyretic - only for 3 days. In children, it is advisable to reduce this period as much as possible. If it was not possible to achieve the effect within the specified time, it is necessary to agree with the doctor on further use, or change the therapeutic course. For anorexia and exhaustion, the dosage is adjusted individually, since the risk of adverse reactions to paracetamol increases.
Like other NSAIDs, Ibuklin is not an absolutely safe drug, therefore, even in the absence of an overdose, adverse reactions are possible (especially pronounced in children), partly due to the high sensitivity of the body. The main reactions to Ibuklin Junior are:
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Adult Ibuklin has a higher dosage of active substances, so the number of unwanted responses from the body is higher. Absolutely all internal systems can be affected. In addition to the digestive and circulatory reactions already mentioned above, which are also relevant for regular Ibuklin, the following side effects are possible:
To minimize the risk of liver problems, doctors advise not to combine Ibuklin and alcohol, and this medication is not combined with SSRIs. In addition, if symptoms of a peptic ulcer occur (in particular, gastrointestinal bleeding), the drug is discontinued.
The main contraindications to taking Ibuklin (Junior and classic) are renal/liver failure, pregnancy (especially the 1st trimester), children under 2 years of age, inflammation of the gastrointestinal tract (including ulcers), disorders of the hematopoietic process, hyperkalemia, as well as disturbances in the functioning of the visual nerve.
Having figured out what Ibuklin - Junior and Classic - helps with, you should pay attention to the real opinion of consumers on this medicine. Most of the reviews are positive, both for children's medicine and for adults. However, people with high sensitivity of the body note that adverse reactions occur too often, even in adults.