Panavir use. The drug Panavir is an effective treatment for HPV. Release form and composition

Viral infections are familiar to each of us to one degree or another, starting with the fairly common cold on the lips and ending with serious diseases, for example, tick-borne encephalitis. Regardless of the type of virus and the disease it provokes, it is important to provide timely support to the immune system, since the lion’s share of success in treatment depends on it. The Russian herbal drug Panavir is designed to help fight a wide range of viral infections due to its strong immunomodulatory effect.

Panavir is a progressive Russian development. The drug has been produced by National Research Company LLC since 2008 and is produced at the Institute of Molecular Genetics of the Russian Academy of Sciences. The development of the technology was carried out on the basis of several research institutes. In 2013, the development team was awarded a government prize in the field of science and technology for the creation and production of Panavir. Meanwhile, the substance Panavir is not patented, and the drug itself is not listed on the WHO list of drugs, since the manufacturer did not submit the drug for registration in the EU and the USA.

What it consists of and how it works

The active ingredient of Panavir is potato shoot extract (a polysaccharide that belongs to the class of hexose glycosides). Excipients are used only to facilitate the administration or administration of the drug, depending on the form of release.

The drug stimulates the induction of endogenous interferons (literally increases the body’s own immunity) and prevents the synthesis of viral proteins - this is responsible for the antiviral and immunomodulatory effect

It has antipyretic, anti-inflammatory and analgesic (for thermal irritation: burns, frostbite) properties. In the treatment of gastrointestinal ulcers, Panavir demonstrated significant wound healing function.

>>We recommend: if you are interested in effective methods of getting rid of chronic runny nose, pharyngitis, tonsillitis, bronchitis and persistent colds, then be sure to check out this site page after reading this article. The information is based on the author’s personal experience and has helped many people, we hope it will help you too. Now let's return to the article.<<

Release form

The manufacturer produces a fairly wide range of the drug. Depending on the location of the infection and the area of ​​application, there are several forms of release of Panavir:

  • spray (Intimate and Inlight);
  • gel (3 g and 30 g);
  • suppositories (vaginal and rectal);
  • solution for injection (2/5 ampoules per package).


Contrary to misconception, Panavir is not available in tablets; confusion arose due to the fact that some patients call vaginal suppositories “tablets.”

All types of medicines, except gel and sprays, are available with a prescription. The shelf life of Panavir is 3 years from the date of production.

Who can take Panavir and who can’t?

Due to the fact that the maximum effectiveness of treatment depends on the method of delivery of the high-molecular polysaccharide, the indications for use for different forms of release of Panavir also differ.

Injection

The Panavir injection solution has the widest list of indications - this dosage form ensures the fastest possible penetration of the drug to the internal organs directly through the bloodstream. The solution in ampoules (injections) is used in therapy:

Intravenous injections of Panavir can be used in the treatment of children over 12 years of age and those who are not allergic to the components of the drug. According to research, the drug is also not contraindicated in pregnant women, but only if the health benefits to the pregnant woman outweigh the possible risk of complications for the fetus. The lactation period is an absolute contraindication for taking Panavir intravenously.

Rectal suppositories

Almost the same list of indications contains instructions for the use of Panavir rectal suppositories:

Suppositories should not be used by pregnant and lactating women, children under 12 years of age and those who are hypersensitive to the ingredients of the medicine. In rare cases, patients develop hypersensitivity as a side effect of using suppositories.

Vaginal suppositories

Panavir vaginal suppositories are used only as part of complex therapy for genital herpes in women over 18 years of age. In addition to being a minor, the list of contraindications includes individual intolerance to the drug or its components, pregnancy and lactation, as well as kidney and liver diseases. Despite the fact that cases of overdose when taking Panavir were not recorded in any of the studies, vaginal suppositories can cause a local reaction in the form of irritation and allergic itching.

The list of indications for the use of Panavir gel is also narrow - it is used only for the treatment of rashes on the mucous membrane and skin characteristic of herpetic infections. The list of contraindications includes: pregnancy, lactation and hypersensitivity to the components of the gel. Panavir gel may cause local skin irritation.

Panavir is an original domestic antiviral drug based on medicinal plant raw materials, which has a wide range of antiviral effects. Increases the body's resistance to viral infections and promotes the formation by immune cells of the main endogenous protective protein - interferon. The active ingredient of the drug is an extract of the Nightshade plant. Panavir is endowed with original pharmacological effects, is well tolerated and demonstrates good results when traditional antiviral drugs do not cope with the task or are contraindicated for use. Panavir is used in complex therapy of the following diseases:

Herpes simplex virus (including genital herpes, ophthalmic herpes, herpes zoster);

Human papillomavirus (including anogenital warts);

ARVI, influenza;

Cytomegalovirus;

Gastric and duodenal ulcers;

Spring-summer tick-borne meningoencephalitis;

Rheumatoid arthritis;

Inflammation of the prostate gland.

Panavir is available in the form of a solution for injection, rectal and vaginal suppositories, and gel. Regardless of the dosage form, it is well tolerated by the body. Clinical studies have demonstrated the absence of allergenic, teratogenic, and carcinogenic effects.

It has antiviral, immunomodulatory, anti-inflammatory, analgesic and antipyretic effects. For stomach and duodenal ulcers, it exhibits wound-healing properties. Direct contraindications to the use of the drug are age under 12 years, individual intolerance (allergy to glucose, mannose, xylose and other components), and the period of breastfeeding. Use during pregnancy is possible only after assessing the benefit/risk ratio. In case of herpesvirus infection, Panavir in the form of systemic and/or local therapy helps reduce the duration of the acute phase of diseases, accelerates the healing of skin and mucous membrane lesions, prolongs the period of remission, increasing the quality of life of patients. In a study of the effectiveness of the drug in patients with recurrent genital herpes, positive treatment results were achieved in 95.8% of study participants. The cure of patients correlated with the restoration of the production of their own interferons. When treating labial herpes, the drug reliably reduces the duration of relapse by half and increases the period between relapses by 1.5-2 times. Significant improvement occurs in 70% of patients, improvement in 18%. There were no cases of clinically significant adverse reactions that led to drug discontinuation.

Pharmacology

Antiviral agent of plant origin. High molecular weight polysaccharide belonging to the class of hexose glycosides. Increases the body's nonspecific resistance to various infections and promotes the induction of interferon synthesis.

Pharmacokinetics

When administered intravenously, polysaccharides are detected in the blood within 5 minutes after administration and are captured by the cells of the RES, liver and spleen. After 20-30 minutes they are found in urine and exhaled air.

Release form

3 g - aluminum tubes (1) - cardboard packs.
5 g - aluminum tubes (1) - cardboard packs.
10 g - aluminum tubes (1) - cardboard packs.
30 g - aluminum tubes (1) - cardboard packs.

Dosage

IV infusion slowly, 200 mcg.
For tick-borne encephalitis, it is administered 2 times with an interval of 48 or 24 hours. If necessary, the course of treatment is repeated after 1 month.

For CMV or human papillomavirus infection, administer 3 times with an interval of 48 hours during the 1st week and 2 times with an interval of 72 hours for 2 weeks.

Side effects

Possible: allergic reactions.

Indications

As part of complex therapy for tick-borne encephalitis (reducing the viral load and relieving neurological symptoms, including anisoreflexia, decreased reflexes, pain at the exit points of the cranial nerves, nystagmus).

As part of complex therapy: herpes virus infections of various localizations (including recurrent genital herpes, Herpes zoster and ophthalmic herpes).

Decreased immunity in combination with infectious diseases.

Cytomegalovirus infection in combination with recurrent miscarriage.

As part of complex therapy: human papillomavirus infection (anogenital warts).

Contraindications

Severe diseases of the kidneys and spleen, lactation period, childhood, hypersensitivity to herbal remedies.

Features of application

Use during pregnancy and breastfeeding

Use with caution during pregnancy. Contraindicated during lactation.

Use for renal impairment

Contraindicated in severe kidney disease.

Panavir is a Russian-made antiviral drug that has a wide spectrum of action. Contains natural plant raw materials as active ingredients.

It was developed based on the discovery of Nobel Prize laureate N.N. Semenov about the powerful immunostimulating properties of biologically active substances contained in rapidly dividing cells of any plants.

The active ingredient Panavir strengthens the body's immune system, increasing its resistance to infections and viruses. When using Panavir and analogues of the drug based on Nightshade polysaccharides, the level of interferon, a protective protein that is produced in the body when infected with viral infections, significantly increases.

Clinical and pharmacological group

Antiviral drug with a broad spectrum of action.

Conditions for dispensing from pharmacies

Dispensed without a doctor's prescription.

Prices

How much does Panavir spray cost in pharmacies? The average price is 340 rubles.

Release form and composition

Panavir spray is available in two versions. One of them is called Inlight, and the other Intimate. It’s easy to guess from the name that the first type is used to treat infections of the oral cavity, and the second to treat the genitals. The active ingredients remain the same.

Spray composition:

  • active ingredient: Panavir (polysaccharides of Solanum tuberosum potato shoots) or eucalyptus oil and Panavir;
  • additional components: polyethylene glycol, lanthanum nitrate, sodium hydroxide, PEG-40 hydrogenated castor oil, water.

Pharmacological effect

Panavir is a drug with antiviral and immunomodulatory effects. It contains Solanum tuberosum shoot extract. The main active ingredient of the extract is a hexose glycoside, which includes mannose, rhamnose, galactose, arabinose, glucose, xylose and uronic acids.

During treatment with Panavir, there is an increase in the production of interferon and an increase in nonspecific immunity. The drug has an antiviral effect due to the ability of the active substance to inhibit the synthesis of viral DNA in cells that have been infected by the virus. Panavir in therapeutic doses is tolerated normally, there are no negative effects (allergenic, mutagenic, teratogenic, carcinogenic, embryotoxic) on the body.

The drug also has analgesic and anti-inflammatory properties, produces a certain regenerative effect, and accelerates the process of scarring of ulcers. It also has an antipyretic effect. The ability of the drug to improve the functions of the optic nerve and retina is noted.

Indications for use

Spray gel Panavir Inlight is used to prevent and relieve symptoms of diseases caused by viruses, bacteria and fungi: ARVI, influenza, acute respiratory infections, viral; for infectious and inflammatory diseases of the external genitalia. The drug can also be prescribed for the prevention of cervical cancer due to human papillomavirus infection. The use of Panavir gel after removal helps to avoid their reappearance.

Panavir intimate gel is indicated in the following cases:

  • Operations to remove condylomas. After such a surgical intervention, it is recommended to treat tissues, including the mucous membranes of the genital organs;
  • Venereal symptoms due to hormonal imbalance. When hormonal status changes, itching, dryness and burning may occur;
  • HPV with high oncogenicity. In this case, the spray acts as a preventative measure against cervical cancer;
  • Changes in microflora. If you have problems with immunity, the chance of developing infections and inflammations in the genital area is especially high. Such processes are characterized by changes in microflora, which becomes a signal for the use of intimate spray.

Unpleasant sensations, such as itching and burning, sometimes occur after sexual intercourse. In this case, you can again turn to the help of Panavir. Moreover, the medicine is used as a prophylaxis against sexually transmitted pathologies. It can be used after completion of unprotected intercourse.

Most often, Panavir is used in complex therapy of human papillomavirus and human papillomavirus. It is prescribed against interferon-deficiency conditions. They can be diagnosed in women who are planning to become pregnant in the near future.

As it becomes clear from the indications, the drug (especially in the gynecological field) does not act as an independent medicine. This is only an adjuvant drug that is most often prescribed for preventive purposes, but it also contributes to more effective treatment through other drugs.

Contraindications

The only contraindication to the use of Inlight spray is individual intolerance to the components of the product.

Spray Panavir Inlight: instructions for use

Take out the nozzle intended for treating the oral cavity and ENT organs from the box and place it tightly on the bottle. Then insert the nozzle shallowly into the mouth or nose and press 2 – 3 times.

For the treatment and prevention of ARVI and influenza, as well as maintaining the mouth and nose in a normally functioning state, Inlight spray must be used twice a day - morning and evening for a long time. The spray can be used daily.

If necessary, Inlight Panavir can be used to treat the genitals instead of Intim Panavir by wearing the second nozzle included in the kit.

Spray Panavir Intim: instructions for use

Place the nozzle included in the kit tightly onto the bottle. Then press the nozzle 2 - 3 times, directing the stream to the surface of the skin of the genital organs so that the gel covers it with an even and thin layer. You can rub the gel into the surface of the skin with light massaging movements or leave it to absorb on its own. In addition, by inserting the nozzle into the vagina, you can apply the gel to the mucous membrane, also making 2–3 presses. If you use any attachment not included in the kit, it can be inserted into the vagina no deeper than 2 cm.

The gel should be applied before and after sexual intercourse and can be used every day.

If necessary, Intim Panavir gel spray can be used to treat the oral and nasal cavity instead of Panavir Inlight, since their composition is the same. In this case, to spray the spray, you need to place the bottle on a table or other flat surface, tilt your head over it so that the nozzle enters your mouth or nose 1–2 cm, and then press it with your fingers 2–3 times.

Side effects

Side effects of Panavir dosage forms boil down to possible allergic reactions to the main active substance, or an auxiliary component in the drug. Usually the medication is taken without visible negative consequences.

The drug is non-toxic and can be used for a long time without fear of decreased effectiveness or irritation.

Overdose

Preclinical studies showed low toxicity of the drug, and not a single overdose was recorded. If negative symptoms appear, you should consult your doctor and stop taking the medication.

special instructions

Medical consultation is required before use.

The use of Panavir Inlight spray can be combined with medications for influenza and acute respiratory viral infections, as well as with anti-inflammatory drugs. It has no contraindications for long-term and repeated use. The spray is non-toxic, does not contain hormones and alcohol.

Panavir Inlight is not a medicine.

Patients are interested in how to take Panavir for HPV. The treatment regimen for papillomas includes both removal of large tumors using various methods, as well as conservative treatment aimed at reducing the activity of the virus and strengthening the immune system.

Will Panavir help?

Treating papilloma with Panavir gives good results. The main active ingredient of the drug is a hexose glycoside, which is isolated from potato shoots. The main effect is antiviral and immunostimulating.

Instructions for using Panovir for condylomas and papillomas should be studied in full. The drug has the ability to directly act on the pathogen. It prevents the reconstruction of the DNA and RNA chains of the virus. When used correctly, the human body gains the ability to resist the virus itself. Under the influence of the drug, the production of alpha-interferon increases and at the same time the synthesis of gamma-interferon is normalized, while the reaction of mediators to inflammation decreases, swelling disappears in the places where the inflammatory process began.

An important advantage of this drug is the complete absence of carcinogenic, teratogenic, mutagenic and embryotoxic effects that some types of drugs used to treat papillomavirus have.

The drug does not harm humans, therefore it is allowed to be used by pregnant women up to the 2nd trimester; further treatment can only be carried out under the strict supervision of a doctor, since the use of Panavir at this stage of pregnancy must be justified by the possible positive effect exceeding the risk of negative effects on the fetus.

How to use Panavir?

Panavir is available in 4 forms: injection solution, ointment, suppositories, spray.

When using the drug, the patient needs to know that Panavir can alleviate a person’s condition and prevent the appearance of new formations, but the full treatment will have a positive effect when Panavir is combined with other drugs used to treat ICP. Any of the products containing a hexose glycoside should not be taken without a doctor’s prescription. Panavir for papillomas can be used in treatment, which will be carried out with medications or using surgical methods of treatment.

Hardware treatment is often carried out in conjunction with medication. After removal of papillomas and candylomas, the use of the medicine accelerates the healing of the mucous membrane and skin. Today, Panavir is one of the effective drugs successfully used to treat human papillomavirus infection.

The drug has undergone rigorous testing. The drug turned out to be capable of producing interferon. The active substance, entering the body, leads to the synthesis of active protective proteins that help cells successfully resist the introduction of the virus. As a result, the rate of cell infection decreases sharply.

The drug successfully copes with its main task - bringing the virus into a dormant state. None of the modern drugs, including Panovir, can completely destroy the virus. In addition to the tasks associated with suppressing the virus, the drug has the following properties:

  • antipyretic;
  • pain reliever;
  • wound healing.

After completing the full course of treatment with the drug, you must undergo examination.

Thank you

The site provides reference information for informational purposes only. Diagnosis and treatment of diseases must be carried out under the supervision of a specialist. All drugs have contraindications. Consultation with a specialist is required!

Panavir represents Russian antiviral drug with a wide spectrum of action, containing natural plant raw materials as active components. The drug was created based on the discovery of Nobel Prize laureate N.N. Semenov about the powerful immunostimulating properties of biologically active substances contained in rapidly dividing cells of any plants.

The active component of Panavir has an antiviral and immunomodulatory effect, therefore it allows you to cure various diseases with short courses. Currently, Panavir is used in the treatment of herpes, papillomas, condylomas, tick-borne encephalitis, cytomegalovirus infection, including in pregnant women, as well as other infectious diseases caused by viruses or opportunistic bacteria.

Names, composition and release forms of Panavir

Currently, Panavir is available in the following dosage forms:
  • Solution for intravenous administration;
  • Rectal suppositories (candles);
  • Vaginal suppositories (candles);
  • Gel for external and local use;
  • Gel spray Intim;
  • Gel spray Inlight.
A solution for intravenous administration, rectal and vaginal suppositories, as well as a gel for external and local use are medications produced in different forms under the same name: Panavir. Gel spray Intim and Inlight are a gel in a tube that can be sprayed like a regular aerosol spray. These gel sprays Intim and Inlight are not medicines, but belong to prophylactic agents containing the same active ingredients as the drugs Panavir, but in lower dosages. Panavir Intim and Inlight are often called simply sprays, suppositories - suppositories, solution for intravenous use - ampoules. In the further text of the article, we will also use these stable and understandable designations for the various forms of the drug Panavir.

As an active component, all dosage forms of Panavir contain purified extract from potato tops shoots (Solanum tuberosum). The main active ingredient of the extract is a complex saccharide consisting of glucose, rhamnose, arabinose, mannose, xylose, galactose and uronic acids. In principle, this extract from potato tops has a patented name Panavir, which gave the name to all forms of the drug.

Solution for intravenous administration, gel, rectal and vaginal suppositories Panavir as an active component contain 200 mcg of potato shoot extract in one ampoule or suppository. As auxiliary components, the solution for intravenous administration contains water and table salt, rectal suppositories - confectionery fat, paraffin and T2 emulsifier, vaginal suppositories - macrogol 1500 and 400, and gel for external and local use - glycerin, macrogol 400 and 4000, ethanol, sodium hydroxide, lanthanum nitrate hexahydrate and water.

Gel sprays Panavir Intim and Inlight have almost the same composition:

  • Polyethylene glycol;
  • Water;
  • Lantana nitrate;
  • Sodium hydroxide;
  • Castor oil;
  • Eucalyptus oil;
  • Potato shoot extract.
The differences between Intim and Inlight gel sprays lie in the area of ​​application - the first is used to prevent infection of the genitals, and the second - in the oral cavity. Therefore, the two forms of the product have different attachments for ease of use, but otherwise are not fundamentally different from each other.

Therapeutic effects of Panavir

The therapeutic and pharmacological effects of Panavir are determined by the properties of the extract from potato shoots included in the drug. All dosage forms of the drug strengthen the nonspecific component of immunity and activate the production of interferon, which increases the human body's resistance to various viral and some bacterial infections. Thus, Panavir has the following therapeutic and pharmacological effects:
  • Immunomodulatory effect;
  • Antiviral effect;
  • Anti-inflammatory effect;
  • Analgesic effect;
  • Antipyretic effect;
  • Neuroprotective effect;
  • Wound healing effect.
The main therapeutic effects of all dosage forms of Panavir are immunomodulatory and antiviral. The anti-inflammatory effect is due to the immunomodulatory effect, due to which leukocytes and interferon synthesis are activated, and appears only in chronic and protracted pathological processes. Leukocytes enter the focus of a chronic inflammatory process, destroy pathogenic microbes in a short period of time, and interferons activate blood flow and promote the complete removal of decay products and toxins against the background of simultaneous tissue regeneration. Thus, the focus of chronic inflammation is quickly eliminated, and the person recovers. Panavir effectively suppresses chronic inflammatory processes of an infectious or pseudo-allergic nature.

The analgesic effect of Panavir is due to the ability to stop inflammation and suppress pain impulses during temperature irritation, for example, burns, frostbite, etc.

Due to the suppression of inflammation, Panavir is able to moderately reduce body temperature.

Panavir reduces the inflammatory process and damage to nerve cells, increasing their resistance to the negative effects of environmental factors. Thanks to this effect, the drug exhibits moderate neuroprotective properties, thanks to which it is able to improve the functioning of the retina and optic nerve.

For ulcerative defects of the gastric mucosa, Panavir is able to have a pronounced wound-healing effect, accelerating the process of restoring normal tissue structure.

Indications for use of Panavir solution, gel, suppositories and spray

Various dosage forms of Panavir are indicated for use in different conditions, since the method of delivery of the active substance determines the maximum effectiveness for any specific diseases. The solution for intravenous administration has the widest range of indications for use, since this form of delivery of the active substance guarantees its penetration into all organs and tissues. The gel and suppositories have a narrower range of indications, since they are effective only for the treatment of diseases and symptoms manifested by damage to the skin and mucous membranes. And Intim and Inlight gel sprays have the narrowest range of indications for use, since they contain the lowest concentration of the active component.


Solution for intravenous administration Panavir

So, Panavir solution for intravenous administration is indicated for use for the following diseases:
  • Infections caused by various types of herpes virus (for example, genital herpes, herpetic keratitis, chickenpox, herpes zoster, etc.);
  • Cytomegalovirus infection is primary or in the acute stage in the II or III trimesters of pregnancy;
  • Long-lasting and complexly cicatricial ulcers of the stomach and duodenum;
  • Tick-borne encephalitis (to eliminate the pathology of reflexes, nystagmus and pain in the areas where nerves exit the skull);
  • Viral dermatoses;
  • Rheumatoid arthritis in combination with herpes virus infection in people suffering from HIV/AIDS;
  • ARVI;
  • Flu;
  • Chronic bacterial prostatitis (as part of complex therapy).

Rectal suppositories Panavir

Panavir rectal suppositories are indicated for use in the following diseases:
  • Infections caused by various types of herpes virus (for example, genital herpes, herpetic keratitis, chickenpox, shingles, etc.);
  • Decreased immunity due to long-term or severe infectious diseases;
  • Cytomegalovirus infection, including women suffering from recurrent miscarriage;
  • Preparing for pregnancy in the presence of chronic viral infections;
  • Warts in the anus and genital area caused by human papillomavirus;
  • Tick-borne encephalitis (to eliminate the pathology of reflexes, nystagmus and pain in the areas where nerves exit the skull);
  • ARVI;
  • Flu.

Vaginal suppositories Panavir

Panavir vaginal suppositories are indicated for use only as part of complex therapy for genital herpes in women.

Gel for external and local use Panavir

Gel for external and local use Panavir is indicated for use in the treatment of infectious and inflammatory diseases of the skin and mucous membranes (nose, mouth, throat, vagina, urethra, etc.) caused by Herpes simplex viruses 1 and 2. That is, the gel is used for treatment of herpetic rashes and blisters on the skin and mucous membranes.

Gel spray Intim Panavir

Gel-spray Intim Panavir is used to treat the external genitalia of both sexes and the vagina of women after intimacy. Gel spray reduces the risk of contracting various viral infections, and also promotes rapid healing of wounds and restoration of tissue integrity. That is, the indication for the use of Intim Panavir gel spray is the prevention of viral sexually transmitted infections and care of the intimate area.

Gel spray Inlight Panavir

Inlight Panavir gel spray is used as part of the complex treatment of influenza and ARVI, as well as to maintain the oral cavity in a functionally active state. Inlight Panavir is able to prevent infection with ARVI and influenza. That is, the indications for use of Inlight Panavir gel spray are the treatment and prevention of influenza and ARVI, as well as oral care.

Panavir - instructions for use

Each dosage form has its own rules and features of use, so we will consider the instructions for each of them separately.

Solution for intravenous administration Panavir (injections)

Panavir solution is injected into a vein slowly in a stream (by injection, not by dropper). For injection, the contents of the ampoule are transferred into a sterile syringe with a thin needle, and then slowly injected into the ulnar, subclavian or any other vein. The solution in the ampoule is ready for use; it does not need to be diluted or any other substances added. The drug can be administered at any time of the day.

Before using the solution, you must carefully examine it for turbidity. If any, even minimal, degree of turbidity of the solution is noted, then it cannot be used. Only a clear solution without any flakes or inclusions is suitable for use.

A single dosage of Panavir for various diseases and conditions is 200 mcg of potato shoot extract, which corresponds to the contents of one ampoule - 5 ml of solution. That is, for one injection it is necessary to completely use one full ampoule of Panavir solution. The frequency of injections and duration of therapy with Panavir depend on the disease.

For the treatment of herpetic infections and elimination of symptoms of tick-borne encephalitis, Panavir is administered twice in one ampoule with an interval between injections of 24 or 48 hours. If necessary, the course of therapy can be repeated after one month.

For the treatment of cytomegalovirus infection (including during exacerbation in pregnant women) and papillomas on the genitals and anus, Panavir solution is administered according to the following scheme:
1. In the first week, one ampoule every other day (a total of three injections during the week);
2. In the second week, one ampoule every two days (a total of two injections during the week).

To accelerate the scarring of ulcerative defects in the mucous membrane of the stomach or duodenum, five injections of Panavir are required, which are administered one ampoule every other day for 10 days.

Panavir gel is widely used for the treatment of herpetic rashes on the skin and mucous membranes of the mouth and nose in children of all ages. Most often, parents apply Panavir gel to herpes on the child’s lips or elements of chickenpox rash, so that they quickly go away, do not itch and do not cause a painful desire to scratch and pick off the scabs.

The intravenous solution is used only in children over 12 years of age. In this case, a single dosage of the solution for adolescents from 12 to 18 years old is 100 mcg of potato shoot extract, which is equivalent to 2.5 ml or half an ampoule. The solution can be administered to children 2.5 ml once a day. However, usually for the treatment of herpes and tick-borne encephalitis, children are administered half an ampoule of the solution every 1 or 2 days. If necessary, courses of therapy are repeated at monthly intervals. For the treatment of cytomegalovirus infection and papillomas, children are administered half an ampoule of Panavir solution according to the following scheme:

1. Half an ampoule of solution every other day for a week;
2. Half an ampoule of solution every two days during the second week.

Panavir Inlight gel spray is widely used in the complex treatment of viral inflammatory diseases of the throat, mouth, nose and pharynx in children. This spray is often called “children’s Panavir” precisely because of its widespread use in pediatrics. So, the throat, mouth or nasal passages are treated with a spray to speed up recovery and relieve symptoms of a viral infection. Most often, Panavir Inlight spray is used for a runny nose, pharyngitis, viral tonsillitis and other inflammations of the ENT organs caused by ARVI, influenza, herpangina or other viral infections to which children are very susceptible.

Naturally, such clinical trials on pregnant women, for obvious ethical reasons, were not carried out, therefore, according to the existing international regulations on the preparation of instructions for drugs, the manufacturer must indicate that Panavir is contraindicated during pregnancy and breastfeeding.

But during the treatment of pregnant women who needed it for health reasons, it was found that the solution for intravenous administration is quite safe, since it does not have a negative effect on the fetus, and therefore can be used throughout the entire period of gestation. Therefore, the indications for use of Panavir solution indicate the treatment of cytomegalovirus, herpetic and other viral infections during pregnancy.

There are no similar data regarding rectal and vaginal suppositories, so they are prohibited for use during pregnancy.

Panavir gel for external and local use can be used during pregnancy only if the expected benefit to the mother outweighs all possible risks to the fetus. This formulation means that targeted studies of the safety of the gel for the fetus have not been conducted, but a fairly large number of women used it during pregnancy and no fetal pathology was observed. That is, based on observations, the drug can be allowed to be used during pregnancy, but due to the lack of experimental data, this cannot be done according to international regulations. Under such circumstances, the manufacturer indicates in the instructions that the drug can be used if the risks are lower than the expected benefits. In practice, this means that Panavir gel has a fairly high level of safety and can be used by pregnant women if necessary.

Panavir Intim and Inlight sprays can be used during pregnancy because, firstly, they contain a small amount of active substance, and secondly, observational data regarding the gel for external use can be extrapolated from them. And since the gel does not cause negative consequences for the fetus, sprays containing less active substance are not able to negatively affect the growth and development of the embryo.

Side effects

Solution for intravenous administration, rectal and vaginal suppositories Panavir as adverse reactions can only cause hypersensitivity phenomena, for example, itching, rashes, redness of the skin, especially at the injection site. Gel for external use Panavir and sprays Intim and Inlight can also provoke itching and redness of the skin or mucous membrane, but only in those areas to which the drug was applied. These side effects of the gel and sprays quickly go away on their own without any treatment. In general, all forms of Panavir are well tolerated and very rarely cause any side effects.

Contraindications for use

All dosage forms of Panavir are contraindicated in the presence of severe kidney disease, as well as individual intolerance or an allergic reaction to glucose, mannose, rhamnose, arabinose, xylose or other components of the drugs. Panavir Intim and Inlight sprays have no other contraindications for use. And the solution, gel and suppositories have a number of contraindications, which are reflected in the table.

Panavir - analogues

On the pharmaceutical market of the CIS countries there are only analogue drugs of Panavir, which have similar therapeutic effects, but contain other active components. Moreover, drugs produced in the same forms can be considered analogues of various dosage forms of Panavir. For example, analogues of Panavir suppositories will be other suppositories, etc. Analogues of Panavir solution can be considered other solutions and lyophilisates for their preparation, as well as tablets or capsules for oral administration.

So, the following drugs are analogues of Panavir:

  • Allokin-alpha lyophilisate for the preparation of a solution for subcutaneous administration;
  • Alpizarin tablets;
  • Amizon tablets;
  • Amiksin tablets;
  • Arbidol capsules and tablets;
  • Armenicum concentrate for the preparation of solution for infusion;
  • Viracept powder and tablets for oral administration;
  • Hyporamine tablets and lyophilisate for the preparation of a solution for inhalation or nasal administration;
  • Groprinosin tablets;
  • Isoprinosine tablets;
  • Ingavirin capsules;
  • Isentress tablets;
  • Yodantipyrine tablets;
  • Kagocel tablets;
  • Lavomax tablets;
  • Liracept powder for oral administration;
  • Nikavir tablets;
  • ORVItol NP capsules;
  • Polyferon-CD4 tablets;
  • Proteflazid extract for oral and topical use;
  • Vaginal and rectal suppositories with hyporamin 0.05 g;
  • Tivicay tablets;
  • Tilaxin tablets;
  • Tiloron capsules and tablets;
  • Triazavirin capsules;
  • Ferrovir solution for intramuscular administration;
  • Fuzeon lyophilisate for the preparation of a solution for subcutaneous administration;
  • Celsentry tablets;
  • Ergoferon tablets.

Panavir (gel, suppositories, solution, Inlight and Intim sprays) - reviews

Most reviews of Panavir relate to the experience of using an intravenous solution and rectal or vaginal suppositories, which are used in the complex treatment of human papillomaviruses, herpes or cytomegalovirus. The reviews are contradictory - there are both positive and negative, enthusiastic and accusatory, etc. However, all reviews about Panavir are united by one thing - they are extremely emotional and filled not with analytical calculations, but with impressions and certain established ideas about the expected effect.

From this series, we can conditionally highlight positive reviews left by people who underwent treatment with Panavir and were able to achieve stable remission of viral infections, which is confirmed by the absence of viruses in the tests. In addition, people noted that in addition to this, Panavir increased immunity and for six months they did not suffer from any colds, ARVI or flu.

Some negative reviews are due to the fact that people were unable to achieve remission and the disappearance of viruses from tests. In addition, there are negative reviews about Panavir, which were left by people who did not receive the expected effect and at the same time realized that they used the drug not according to indications, for example, to eliminate the human papillomavirus in tests, and not to reduce papillomas or



Random articles

Up