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Rheumatoid nodules are one of the most common extra-articular signs of RA, occurring in approximately 10% of patients with seropositive RA. They usually develop in the subcutaneous tissue, and especially often in places exposed to pressure and trauma. Favorite localization is the area of the elbow joint and the extensor surface of the forearm (Fig. 3.9).
They are often located on the hands in the area of the interphalangeal and metacarpophalangeal joints, as well as in the soft tissues of the fingertips and palms; they are also observed on the feet in places where shoe pressure is applied, in particular on the heels and along the heel tendons. In people who spend most of their time in a sitting position, nodules are often found on the buttocks and directly above the projection of the ischial tuberosities; in patients confined to bed - in the area of the back of the head, shoulder blades, spine, sacrum. In people who wear glasses, nodules are sometimes observed on the bridge of the nose.
If RA is suspected, a targeted search for nodules is necessary, since they can be single and small, localized in unusual areas and thereby escape the doctor’s attention or be misinterpreted. This is also facilitated by the fact that rheumatoid nodules are almost always painless. Their sensitivity to palpation, and even more so ulceration or suppuration, is very rare.
The size of the nodules ranges from a few millimeters to 3-4 cm in diameter. Small nodules are sometimes so hard that they are mistaken for gouty tophi. Larger ones are characterized by a consistency reminiscent of dense rubber. Occasionally, nodules are perceived as cysts, and sometimes there is some fluid in their center. In many patients, the nodules are mobile in the subcutaneous tissue. However, very often they are tightly fixed to the underlying periosteum or to the fascia and tendons. In the latter case, this can lead to tears or complete ruptures of the tendons (in particular, the heel or extensor fingers on the back of the hand).
The number of nodules varies from one to several dozen. M. Ginsburg et al. (1975) described a special variant of RA, characterized by very modest clinical symptoms of synovitis in combination with numerous rheumatoid nodules with a typical histological structure. This variant, which the authors called rheumatoid nodulosis, occurs in 90% of cases in men, and more often over the age of 40 years. Synovitis can be mild and sometimes reversible (such as “palindromic rheumatism”).
X-rays often reveal clear intraosseous cysts or small erosive changes. RF is detected in the blood serum in a moderate or high titer, which is generally characteristic of almost all patients with rheumatoid nodules. Some patients also have concomitant visceral manifestations, most often pulmonary or pleural.
Rheumatoid nodulosis should be considered as a unique variant of RA, in which specific extra-articular manifestations come to the fore, being clinically more pronounced than the symptoms of synovitis (similar to a number of patients with Kaplan syndrome, Felty syndrome, etc.). At the same time, there is no doubt that in a number of patients, rheumatoid nodulosis after a few years transforms into the classic version of RA with severe polyarthritic syndrome and progressive destruction of joints.
Rice. 3.9. Large rheumatoid nodules in the area of the elbow joints.
Extracutaneous localization of rheumatoid nodules is very rare, but its possibility must be constantly borne in mind, since in some patients it turns out to be the cause of non-standard clinical manifestations. Rheumatoid nodules were found in the synovial membrane of joints (where they sometimes reached large sizes and impeded movement), muscles, bones (promoting their destruction) and tendons, occasionally leading to their rupture.
In most patients with RA, the nodules are clinically asymptomatic; this also applies to rare visceral localizations. However, serious exceptions are possible in this regard, not to mention real diagnostic difficulties. Thus, single or multiple nodules in the pleura and lungs, especially if they precede obvious arthritis, raise the idea of oncological pathology. Some of them disintegrate with the possibility of breaking into the pleural cavity and forming pneumothorax.
In the heart, nodules were found (usually not clinically, but morphologically) in the myocardium, pericardium and on the valve leaflets. Relevant clinical manifestations were conduction disturbances and regurgitation of the mitral or, more commonly, aortic valve.
Very rarely, nodules develop in the retina with visual impairment and sclera with the risk of perforation. When localized on the vocal cords, pain, hoarseness, dysphonia and respiratory distress are possible, although in RA these symptoms are more often associated with damage to the cricoid-arytenoid joints. Asymptomatic rheumatoid nodules in the central nervous system have also been described, and therefore the potential threat of developing symptoms of spinal cord compression cannot be excluded.
Thus, rheumatoid nodules located in the subcutaneous tissue are one of the most specific signs of seropositive RA. Being mostly clinically asymptomatic, they nevertheless indicate an expansion of the springboard of the main pathological process and, according to a number of authors, indicate a more serious prognosis of joint pathology and disease in general.
This judgment, apparently, can be recognized as correct only with a general statistical assessment; the individual prognostic value of rheumatoid nodules is small. Differential diagnosis of various nodular formations in patients with RA is discussed in the “Diagnosis” section.
Erythema nodosum is a fairly common disease that most often occurs in pregnant women. The peculiarity of this disease is that medium-sized nodules are formed on the human body, or more precisely in the area of the legs, thighs and buttocks, which can reach a diameter of 1 to 3 cm. Most often, these nodules are symmetrical and appear on both legs. When pressing on such nodules, the patient notes pain.
Erythema nodosum always has its reasons and never appears just like that. At the same time, the appearance of nodes on the legs is only a manifestation of a disease, the causes of which must be sought much deeper. For many years, the cause of this disease remained unclear. However, it became clear what could trigger the appearance of such nodules on the limbs. As it turned out, the presence of nodes is more often recorded in pregnant women and in women who used hormonal contraception.
Also today it has become known that the following reasons can become a provoking factor:
However, in order for erythema nodosum to begin to manifest itself, a person must necessarily have vascular diseases of the lower extremities, or more precisely, varicose veins and thrombophlebitis. But there are also cases when this illness is an independent disease. And here it is simply impossible to find out the reason for its development.
Erythema nodosum of the lower extremities can occur in two forms - acute and chronic. And each of these two forms has its own clinical manifestations.
A typical manifestation of this disease is the presence of dense nodes that are located in the subcutaneous tissue or in the deep parts of the dermis. The skin over such formations is smooth and red. In addition, such “bumps” rise slightly above the skin, and it is impossible to determine their exact boundaries due to the swelling of the tissues surrounding them.
Nodes only grow to a certain size. As for the pain syndrome, it can be quite pronounced and manifest itself not only during palpation of the formations, but also with complete rest, while there is no itching.
After 3–5 days from the start of the appearance of nodules, they begin to disappear spontaneously. At the same time, they are strongly compacted, but do not disintegrate. The skin over the nodule gradually changes color, which is very similar to a bruise.
Erythema nodosum on the legs most often begins acutely and unexpectedly. The patient complains of general malaise, increased body temperature, lack of appetite, and chills. More than half of patients experience joint pain and stiffness in the morning. Some may experience symptoms of joint inflammation - swelling and redness of the skin over it, the presence of intra-articular effusion. Moreover, all these symptoms may precede the appearance of subcutaneous nodes by several days.
The nodules themselves completely disappear only after 2-3 weeks from the beginning of their appearance. In their place, skin hyperpigmentation and peeling appear. Simultaneously with the disappearance of the nodules, the articular syndrome also disappears. In total, the disease lasts about a month, in some cases a little more.
It is rare, but it still happens that erythema nodosum has a long chronic course. Exacerbations are manifested by the appearance of small, single nodes, which feel quite dense to the touch and can persist for several months. In addition, joint damage is well expressed, without significant deformation.
Erythema nodosum always requires diagnosis to be confirmed. The first thing you need to do is a blood test, which determines the increased number of leukocytes and ESR. If a bacteriological culture is carried out from the nasopharynx, a streptococcal infection is often isolated. If articular syndrome is present, then this is a reason to go to a rheumatologist.
If the diagnosis cannot be made based on clinical signs, then a biopsy of one of the nodules on the legs has to be performed. In order to understand what caused the disease, consultation with many specialists and studies such as:
Once the cause of the disease has been identified, treatment can begin.
Treatment of erythema nodosum will be successful only if the underlying disease is treated. Treatment of chronic foci of infection, mandatory treatment with the latest generation of antibiotics, and desensitizing therapy are required. To relieve inflammation, NSAIDs are used - nurofen, ibuprofen, diclofenac, and many others. Treatments such as cryopharesis, plasmapheresis, hemosorption, and laser irradiation of blood can be used.
Local treatment is also carried out. Anti-inflammatory and corticosteroid ointments and bandages with dimexide are used. Among the numerous physiotherapeutic methods, ultraviolet irradiation, magnetic therapy, laser therapy, and phonophoresis are used. However, if erythema nodosum on the legs, a photo of which can be viewed on the Internet, appears during pregnancy, then treatment here requires special attention, since many drugs are contraindicated in this case.
Diseases of the musculoskeletal system always bring a lot of discomfort and pain. They are provoked by various reasons. But there are pathologies of a systemic nature that cannot be completely cured, and the patient should be given maximum assistance. Such a disease is rheumatoid arthritis.
The pathology is quite common: the disease occurs more often in women than in men. Age does not matter for rheumatoid arthritis, as it has become much younger in recent years.
The disease is progressive in nature and can lead to complete disability of a person. Rheumatoid arthritis is a systemic disease whose etiology is still unknown. It is characterized by damage mainly to the connective tissue of the joint; erosive changes occur in the joints.
Rheumatoid disease is progressive and chronic. Over time, complete deformation and destruction of the joints occurs. The joints lose mobility, and the person becomes disabled.
The disease can affect the skeleton and internal organs: heart, kidneys, blood vessels, lungs, muscles. The pathology begins with an inflammatory process, which is localized in the synovial membrane of the joint. Over time, it spreads to cartilage and bones. The speed of development of the disease varies.
The body’s autoimmune reaction also leads to aggravation of the patient’s condition: the defense system begins to destroy its cells. The small joints of the legs and arms are most often affected. However, the inflammatory process can affect other areas of the body.
Features of the disease:
Main reasons:
Any infection can cause systemic pathology, so you need to take responsibility for your own health.
First signs:
Most often, the first signs are ignored, so the disease can progress further.
Joint symptoms of rheumatoid arthritis:
Other signs of the disease:
More details
Extra-articular symptoms of arthritis:
Rheumatoid arthritis can affect the gastrointestinal tract, nervous system, respiratory system, kidneys, heart and blood vessels. Therefore, the disease can cause additional pathologies in these organs: colitis, neuropathy, polyneuritis, pleurisy, pneumonitis, bronchiolitis, amyloidosis, arteritis, myocarditis, pericarditis.
The early phase of the disease is characterized by the appearance of exudate, and effusion is present in the joints. When palpating the affected joints, the patient feels sharp pain. Limb movement is significantly limited. The skin over the joint is hot to the touch and red in color.
Not only small but also large joints (hip) can be damaged. Spinal lesions are rare: the spinal column is affected only at the last stage of development of rheumatoid arthritis, mainly the cervical region. If the inflammatory process spreads to the temporomandibular joint, the patient cannot open his mouth normally and has difficulty eating.
Classification of the disease is very important for prescribing treatment. There is some dependence on the patient’s age: the peak development of the pathology can be reached only at 50 years old, although it can begin to develop at 20.
There are types of disease:
As for the stages of development of rheumatoid arthritis, there are only 4 of them:
Diagnosis is difficult, since most symptoms are not specific. The diagnosis must be differentiated.
It is necessary to pay attention to what symptoms the patient will exhibit. For example, a doctor can already make a diagnosis based on the following criteria:
Diagnostic tests are prescribed:
Signs of rheumatoid arthritis may include the following symptoms: skin diseases (vasculitis, dermatitis), lung pathologies, eye diseases, disorders of the circulatory system, diseases of the cardiovascular system (heart attack, stroke). Diagnosis of rheumatoid arthritis can also be complicated by the fact that the symptoms of the disease are similar to other disorders: gout, fibromyalgia, osteoarthritis, arthrosis, systemic lupus, infectious inflammation of the joint.
The doctor is obliged:
Only differentiated diagnostics will accurately determine the presence of the disease and prescribe the necessary treatment.
Juvenile rheumatoid arthritis is a fairly severe form of chronic inflammatory process that affects children under 16 years of age. The etiology of the disease is unknown, and its pathogenesis is very complex. Very often this form of arthritis ends in disability. This disease of the supporting apparatus in children is quite rare, but compared to other skeletal pathologies it ranks first. The symptoms of the pathology are in many ways similar to the clinical picture in adults, but its manifestations are more pronounced.
For example, the temperature rises to 38-39 degrees. A polymorphic allergic rash may appear on the skin, the spleen, liver, and regional lymph nodes become enlarged, and anemia occurs. If the disease was detected in a child under two years of age, he may stop walking altogether. This form of pathology can cause eye damage, which is more common in girls of preschool age. The quality of treatment depends on how quickly the diagnosis was made and how correctly the treatment was carried out. Therapy won't be easy.
Rheumatoid arthritis cannot be completely cured. However, this does not mean that there is no need to fight it.
Key treatments:
Rheumatoid arthritis must be treated, taking into account the nature of the disease and the severity of its symptoms. The patient may not need to take any serious medications. At the initial stage of pathology development, treatment is gentle. If it is ineffective, radical types of therapy are used.
The affected joints need to be given rest, as heavy, prolonged stress only increases inflammation. To completely immobilize the joint, orthopedic splints are used.
Drug treatment with the prescription of several groups of drugs:
Drug therapy is effective only in combination with physiotherapeutic methods and physical therapy. Exercises in the pool are useful when there is active movement of the joints, but they do not experience stress.
Sometimes the patient is indicated for surgery. Radical intervention is a last resort. Modern medicine makes it possible to completely or partially replace a diseased joint with an artificial one. Thanks to the operation, it is possible to restore normal mobility of the affected joints and avoid loss of ability to work. In some cases, surgery is aimed at fusion of joints, for example, when the foot is affected. Then specialists can achieve a reduction in pain attacks.
During treatment, it is important to use special orthopedic devices: boots, means for grasping objects. They improve a person's quality of life.
Treatment of rheumatoid arthritis is quite effective with the drug Methotrexate. It cannot be purchased freely at pharmacies, as it is sold with a doctor's prescription. The main effect of the medicine is to eliminate compounds that cause the destruction of connective tissue in the joints. The drug prevents erosion of joints and relieves inflammation. Therapy lasts quite a long time. The medicine is used in courses.
Treatment of rheumatoid arthritis is possible not only with medications. Traditional recipes will also be useful, but they are used only after consultation with a doctor. They cannot replace primary therapy.
Useful recipes:
Treatment of rheumatoid arthritis with folk remedies and nutrition is an integral part of complex therapy. However, this is not the preferred method.
Related article: Useful properties and recipes for preparing chestnut tincture - for the treatment of rheumatoid arthritis and more.
Rheumatoid arthritis can cause the following complications:
The appearance of the first symptoms of pathology should alert you, because the lack of treatment leads to the fact that it becomes difficult for the patient not just to live, but to exist.
No specific preventive measures have yet been established. However, some recommendations will make it possible to significantly reduce the frequency of attacks of exacerbation of rheumatoid arthritis.
Arthritis treatment Read more >>
Prevention measures:
Rheumatoid arthritis is a complex disease that shortens life expectancy by 3-12 years. At the same time, patients have a significantly increased risk of heart disease. However, with the use of modern medications and other treatments, this negative impact can be reduced. If you follow the recommendations, therapy can provide a permanent positive result.
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Juvenile rheumatoid arthritis is a chronic joint disease, the nature of which has not yet been established. It is only noted that the inflammatory process in the joints always lasts at least 6 weeks and develops in children and adolescents under the age of 16 years. Mostly girls suffer.
Juvenile rheumatoid arthritis (or juvenile rheumatoid arthritis for short) can develop into severe arthritis or ankylosing spondylitis. All these diseases have serious consequences and can lead to disability of the child. Therefore, treatment of juvenile rheumatoid arthritis should be carried out as early as possible.
Advice: parents should always carefully monitor the child; if he has a positive rheumatoid factor, then juvenile rheumatoid arthritis may occur. The slightest changes in gait, gestures, or coordination of movements are a reason to be examined by a rheumatologist to confirm or deny this.
Juvenile type of arthritis is a collective term that refers to all rheumatoid diseases in children. There is an official classification of law:
The diagnosis is made if the clinical picture of the child’s illness is as follows:
This classification is considered general; each term, taken individually, does not have its own definition and is most often indicated in the medical history as “inflammation of the joints of a chronic nature in children under 16 years of age.”
Juvenile rheumatoid arthritis is a separate nosological entity; its manifestations are very similar to adult rheumatoid arthritis. In children who have been ill for more than three months, the following characteristic symptoms can be noted:
Deformation of small joints of the hands;
Symmetrical polyarthritis of the joints of the arms and legs;
Formation of rheumatoid nodules;
The presence of destructive arthritis.
According to the results of the examination, seropositivity in the Russian Federation is revealed
Based on the nature of the flow, two forms of the Jurassic are distinguished:
According to localization, Jurassic can be:
Juvenile rheumatoid arthritis can be rapidly progressive, moderately progressive or slowly progressive.
The following factors can trigger the development of juvenile arthritis:
In some cases, excessive sun exposure causes illness.
Juvenile rheumatoid arthritis primarily affects large and small joints. At the same time, they are swollen, deformed, the skin is hot to the touch, the child complains of burning pain and stiffness in movements.
Typical localization for the Jurassic is the maxillotemporal joints and the cervical spine. Sometimes it looks like periarthritis of the shoulder, so it is important to make a correct diagnosis.
Such lesions are always accompanied by inflammation, gradual destruction of cartilage tissue and fusion of articular elements.
Extra-articular signs of the disease include:
If the temperature drops, the child literally sweats, his underwear and bed linen get wet through. This Jurassic stage can last from several months to several years if a diagnosis is not made and treatment is not started. And only then joint damage will appear.
Note: red eyes in a child are a typical sign of Jurisprudence, although there is no direct connection between the eyes and joint inflammation.
Acute juvenile rheumatoid arthritis is very difficult. All symptoms appear, the nature of the disease is systemic. Relapses often occur, and treatment is ineffective.
Arthritis in children in this form has the same symptoms as in acute form, but they do not appear as severely and often. At the developmental stage, one joint is affected first, most often the knee or ankle. If the child is very small, he becomes capricious, refuses to get up on his feet, and always asks to be held or sits.
Older children complain of “morning stiffness.” The child cannot get out of bed and perform simple household tasks independently. The gait changes: it becomes very slow, as if every step causes pain. He can remain in this state for up to an hour until the joints develop.
For this reason, parents and doctors often mistake the illness for a simulation, explaining that the child simply does not want to go to school or kindergarten. If the pediatrician claims that the child is faking, it makes sense to go to another, more attentive and qualified physician.
In girls of preschool and primary school age, rheumatoid eye damage is often manifested. This disease is called rheumatoid uevitis, unilateral or bilateral. Since the disease affects all the membranes of the eyeball, in just six months, vision sharply decreases until it is completely lost.
It is rare, but it happens that rheumatoid uevitis manifests itself earlier than the underlying disease - then it is very difficult to make a diagnosis.
In subacute rheumatoid arthritis, 2 to 4 joints are affected; this form of the disease is called oligoarticular.
In this case, the disease is recognized by the following signs:
In young children, the disease is characterized by Still's syndrome, in schoolchildren and adolescents - by Visseler-Fanconi syndrome.
If treatment is not started, secondary amyloidosis may develop, caused by the constant presence of immune complexes in the blood. Amyloid deposition begins on the walls of blood vessels and arteries, in the liver, kidneys, intestines and myocardium. As a result, the functioning of these vital organs is disrupted.
The kidneys are most affected, and large amounts of protein are found in the urine. Therefore, as a rule, with rheumatoid arthritis, children primarily suffer from kidney failure.
In order to accurately diagnose the disease, the doctor may prescribe the following examinations and tests:
Based on the results of tests and examinations, complex therapy is prescribed.
The treatment program for children is drawn up depending on the form of the disease and the condition of the joints. During the “quiet” period, dieting is mandatory. Food should be low in calories, rich in vitamins and polyunsaturated fatty acids. Saturated fatty acids and allergenic foods should be completely avoided.
Non-steroidal anti-inflammatory drugs and glucocorticosteroids are used. Therapy is aimed at stopping the inflammatory process, relieving pain and maintaining the functionality of the joints. All this allows the child to lead a full active life.
Basic treatment includes the use of the following medications:
If the disease is caused by an infection, a course of antibiotic therapy is necessary. If the disease has an immune complex etiology, plasmaphoresis is used. For very severe pain, medications are administered intra-articularly.
In some cases, immunotherapy gives positive results. Immunoglobulin is administered intravenously by drip. It is important to follow the technique of administering the drug. In the first 15 minutes, 10-20 drops of the drug are administered every minute, then the speed increases. You can repeat the procedure every month.
In severe forms of the disease and advanced cases, when conservative treatment methods have proven ineffective, surgery is performed - joint replacement.
As for the treatment of rheumatoid uevitis, this complication is treated jointly by a rheumatologist and an ophthalmologist. For local treatment, a combination of GCS and mydriatics is used. If after a two-week course of such therapy no results are observed or the pathology progresses, cytostatics are prescribed.
They begin to be used after confirmation of an acute or seropositive form of rheumatoid arthritis in a child.
In the fight against the symptoms of the disease, proper nutrition of the child is very important. Salt intake should be minimized. This means that the diet should not contain sausages, hard cheeses, pickles, and homemade food should also be salted very sparingly. This reduces the intake of sodium into the body.
To maintain calcium balance, the menu should include nuts, dairy products, and calcium and vitamin D supplements are also recommended.
To maintain muscle tone and joint mobility, a set of gymnastic exercises is prescribed. Massage, various physical procedures, trips to resorts and sanatoriums are very useful as supportive and preventive measures.
Advice: if a child has been diagnosed with this, you should not limit him from communicating with peers and playing sports. He may well attend various sections and take part in outdoor games. Then, in case of exacerbation of the disease, complications and consequences will be minimized.
It is noted that the disease occurs in a milder, milder form if the child leads an active lifestyle. In weak, lethargic children, on the contrary, the symptoms are always more pronounced.
But: at the same time, it is strictly forbidden to force the child to move, do exercises, etc. He himself must regulate the intensity of physical activity. If discomfort and pain occur during physical activity, then it is necessary to review and adjust exercise therapy and other sports.
If treatment was started late, was carried out in bad faith, or was completely absent, then what is the risk of juvenile rheumatoid arthritis? First of all, the fusion of articular elements will progress. And this leads to their complete dysfunction, immobility, and, as a consequence, the child’s disability.
The effect on the kidneys, liver and heart leads to the development of chronic pathologies of these organs, which also negatively affects the general condition of children. With advanced rheumatoid uevitis, the child may become completely blind. It should be remembered that destroyed joint tissues are not restored. But surgery is not always possible.
Even if you cannot completely get rid of rheumatoid arthritis, this diagnosis will remain for life; you can live it actively, without standing out from other people. But only on condition that treatment was started in a timely manner and carried out carefully and comprehensively.
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Inflammation of the joints brings the patient a lot of unpleasant sensations: pain, stiffness, impaired mobility. Along with this, specific nodules may appear under the skin. Despite the fact that such formations are painless and look like a minor cosmetic defect, they are the most important diagnostic sign of severe systemic diseases such as rheumatism and rheumatoid arthritis.
These are dense subcutaneous or periosteal formations, consisting of accumulations of necrotic areas of connective tissue.
Attention! Nodules occur in 20-30% of patients with seropositive rheumatoid arthritis (RA) during an exacerbation.
The etiology of the formations is not fully understood, but there is a theory according to which the nodules appear due to small vessel vasculitis caused by autoimmune disorders. In 5-7% of patients with systemic lupus erythematosus, similar formations are noted.
Nodules in RA are dense to the touch, mobile, painless, round-convex in shape. They develop most often in the subcutaneous tissue, in areas of high pressure. Their size ranges from a few millimeters to 3-4 cm in diameter. The number of formations is individual for each patient - from one to several dozen.
Nodules appear mainly in the area of the elbows, forearms, hands and small joints of the fingers. Localization may vary depending on the individual characteristics of the patient:
Cutaneous:
Visceral:
Attention! Visceral formation of nodules is asymptomatic, but when they grow together with surrounding tissues, disturbances in the functioning of internal organs occur.
Since the appearance of nodules occurs painlessly, many patients do not pay attention to them. In this regard, if RA is suspected, a targeted search for tumors on the skin is carried out with parallel laboratory diagnostics:
The results of the study reveal markers of the inflammatory process: leukocytosis, increased ESR and C-reactive protein, decreased hemoglobin levels. In 90% of cases, rheumatoid factor is present in the blood.
When biopsy of a rheumatoid nodule, a characteristic histological picture is noted: fibrous tissue with limited foci of collagen necrosis, around which macrophages are located in a palisade. In addition, granulation tissue and inflammation of blood vessels caused by high concentrations of immune complexes (IgG and IgM) and rheumatoid factor are detected.
Such nodules develop in the subcutaneous tissue, in the tissues of aponeuroses, tendons, fascia and articular capsules. They are located near the source of inflammation, most often in the bend of the elbow, knee, ankle joints, in the area of the spinous processes of the spine, ankles, back of the head and scalp.
Appear symmetrically one at a time or in groups. The size of the nodules varies from 2 mm to 2 cm, so it is better to diagnose them with the joint maximally flexed.
Despite the external similarity, rheumatic nodules differ from rheumatoid ones in a number of clinical and microscopic signs:
For the differential diagnosis of RA and rheumatism, a tissue biopsy of the nodule and a blood test for rheumatoid factor are prescribed.
Separate treatment for rheumatic nodules is not carried out, since they disappear on their own after the cessation of the inflammatory process in the body. The following drugs are used for drug therapy of rheumatism:
Complex therapy prevents damage to new tissues and significantly accelerates the resorption of rheumatic nodules.
Additionally, to eliminate rheumatic symptoms, you can use traditional medicine:
For joint diseases, pine baths (or turpentine) are effectively used.
A health program dedicated to the manifestations and treatment of rheumatoid arthritis.
Nodules that appear harmless at first glance indicate an inflammatory pathology of the entire body. Therefore, if any subcutaneous formations are detected, you should not self-medicate. You need to immediately consult a doctor and carry out full-fledged therapy for the underlying disease.
There are quite a lot of skin diseases in which various nodules and swellings appear on its surface or directly under it. This article will describe the most common pathologies in which cutaneous and subcutaneous nodules form.
The nodules on the skin, photos of which can be seen below, are small (up to 5 millimeters), clearly defined tubercles. If the elements are larger, then they are called nodes.
Sometimes the nodules are painless, in other cases they cause pain on palpation.
The main types of skin nodes:
Whiteheads. These are painless white nodules on the face. They are formed as a result of blockage of the sebaceous glands.
Acne. With acne, painful, dense red nodules appear on the skin (photo can be seen below). They gradually mature, and a white purulent head appears in their center. The skin near the lesions is inflamed and swollen. After some time, the pimple opens, the purulent contents come out, and a crust forms in place of the acne. Often, after acne disappears, scars remain.
Senile angioma. These are harmless, soft subcutaneous nodules on the body that are purple-red in color. They usually appear in older people.
Warts. They are single, painless formations on the surface of the epidermis (sometimes an accumulation of warts is observed). Most often they form on the fingers.
Cutaneous horn. It is a papillary soft nodule under the skin on the neck or under the arms. Most often appears in older people. The cutaneous horn does not pose a health hazard, but if it grows strongly, it can cause inconvenience.
Uncommon causes of skin nodules:
Rare reasons:
Subcutaneous lumps sometimes do not cause much discomfort to the patient, but most often they are quite painful. Nodules under the skin can appear as a result of exposure to the following factors:
Main types of nodules:
Lipoma(another name is wen). It is a movable, elastic and soft seal. The size of a lipoma is usually 1-5 centimeters. Such nodules appear on the abdomen under the skin, or in any other places.
Hygroma. These are inactive dense tumor-like nodules under the skin on the arms. They have smooth edges and an oval shape. Appear most often after injuries. Hygroma does not pose a health hazard and does not hurt. It can only cause cosmetic discomfort.
Atheroma. Appears on those areas of the skin that have a lot of sebaceous glands. It is a round, dense formation with clearly defined boundaries. It can become inflamed and fester. At the request of the patient, the formation can be removed surgically.
Inflammation of the lymph nodes. It manifests itself as the formation of a painful lump under the skin. Usually the cause of inflammation is an infectious disease.
Nodules on the joints. May be a symptom of joint diseases. For example, the formation of subcutaneous nodules in the elbow joint can be a symptom of rheumatoid arthritis. Nodules on the joints of the fingers are observed with deforming osteoarthritis.
Abscess. In this case, the lump hurts, the patient’s temperature rises, and the general condition worsens. The skin over the lesion is swollen and hyperemic. This clinical picture occurs as a result of the penetration of pathogenic microorganisms into the tissues, which enter there through damaged skin and cause suppuration. If an abscess occurs, you must contact a surgeon, otherwise complications may develop.
A node is a dense formation that appears when infiltrate accumulates in the subcutaneous tissue. Nodules on the skin (photo can be seen below) can subsequently ulcerate and scar.
Red nodules on the skin can be a symptom of many diseases. The main reasons for their appearance may be:
Large, itchy, red, firm nodules on the skin are called erythema nodosum. When red nodules appear on the skin, many simply do not pay attention to them, but in vain. After all, they can be one of the symptoms of a number of diseases.
In order to find out the cause of the rash, you need to contact a specialist, who will conduct an examination, prescribe the necessary tests, make a diagnosis and develop an adequate treatment plan.
Nodules under the skin on the hands form in men with palmar fibromatosis (another name is Dupuytren's contracture). This is a disease in which scarring occurs in the tendons of the patient’s palms.
Due to the proliferation of connective tissue, the tendons are shortened, which causes a violation of the extensor function of the fingers. The course of the disease is accompanied by the appearance of nodes under the skin in the area of damaged tendons. With further progression, stiffness of the damaged fingers develops.
The disease has a clear clinical picture, which is difficult to confuse with the symptoms of other diseases. The patient develops nodes under the skin, which leads to a sharp impairment of the extensor function of the fingers.
With further development, the subcutaneous nodes continue to grow. The skin around them becomes dense and gradually fuses with the tissues underneath. This leads to the formation of retractions and bulges in the lesion. Strands and knots are especially clearly visible when the patient tries to straighten the finger.
The reasons for the development of this disease are still unknown. In the early stages, drug treatment is possible, but most often the contracture still continues to progress. Therefore, the most effective treatment method is surgery.
Subcutaneous nodules on the legs often occur with varicose veins. A varicose vein is a pathological change in a vein in which its walls are deformed and thickened. The cause of the appearance of subcutaneous nodes on the legs is varicose veins.
Nodules on the legs under the skin often appear in obese people with a history of cardiovascular disease. The main danger of such nodes is that with severe overstrain of the legs, the thinned tissues of the vessels will disperse, and bleeding will occur, which can only be stopped by surgery.
Almost 20% of people with rheumatoid arthritis develop nodular rashes called rheumatic nodules. They are subcutaneous or periosteal compactions with a diameter of several millimeters to 2 centimeters.
Most often, such rashes are numerous, but painless. They are located near bone structures, often near joints, especially the elbows. In this article we will look at the reasons for the appearance of such nodules and how to treat them.
To date, there are no exact reasons why subcutaneous nodules. There is a version that the development of such formations occurs as a result of changes in the walls of blood vessels that occur due to a malfunction of the immune system.
These subcutaneous formations are sometimes completely invisible, and Only a specialist can diagnose them. It is noted that nodes under the skin in almost all cases are formed with severe joint damage that occurs over a long period of time.
Sometimes, against the background of a complete absence of diseases, pseudorheumatic nodules, which do not cause inconvenience and do not affect the general well-being of a person.
Patients sometimes do not notice the appearance of rheumatoid nodules, since they are almost painless and do not cause any discomfort. Excessive sensitivity and pain of formations, as well as their suppuration or the appearance of ulcers, are quite rare.
Rheumatoid nodules can be of different sizes, for example, small ones are characterized by a dense structure. Because of this, they are often confused with. More voluminous subcutaneous formations have a consistency that resembles dense rubber.
Sometimes they look like a cyst, since a small amount of fluid can form in the middle of the node. In some patients, movement of rheumatic nodes in the subcutaneous tissue is observed, although to a greater extent the neoplasms grow together with nearby tissues.
Also, nodules can be located outside the skin: in the lung, pleura, heart, retina. You can see in more detail what these neoplasms look like in the photo below.
Rheumatoid nodules
If nodules are detected, you should immediately consult a doctor to make an accurate diagnosis. When diagnosed, the rheumatoid form of diseases such as leprosy, erythema nodosum, sarcoidosis, etc. is revealed. To determine the cause, the following are prescribed: types of diagnostic studies:
You might be interested, what is it and how to treat it.
Treatment of rheumatoid nodes is based on the treatment of the underlying disease – rheumatoid arthritis.
In this case The treatment is complex and includes:
When treating rheumatoid arthritis, a specialist prescribes several types of drugs that have a wide spectrum of action. It is important to remember that only a doctor can build the correct therapy, based on the individual characteristics of the patient.
Types of medicines, which are prescribed for the treatment of rheumatoid nodes:
Read also about which ones you can take for your joints.
On the recommendation of a doctor, in addition to the main therapy, it is possible to use traditional medicine. Home remedies are popular because they are natural and have minimal side effects.
Common recipes for rheumatoid nodules:
Rheumatoid arthritis, which causes subcutaneous nodules, is characterized by joint deformation and limited mobility. To reduce symptoms and avoid irreversible consequences, the doctor prescribes physical therapy to the patient.
Attention! Exercises are selected individually for each patient.
Most Popular exercises for rheumatoid arthritis:
When treating rheumatoid arthritis and subcutaneous nodules, it is important to remember that success in the fight against the disease depends on properly selected treatment and timely consultation with a doctor. By following all the specialist’s recommendations, you can defeat the disease and achieve long-term remission, which means everything is in your hands.