Questions. Main antibiotics for chlamydia: drugs, description, action The most powerful antibiotics for chlamydia

Content

Some diseases are dangerous not only by their nature, but also because they pose a threat to others and the patient’s family, so you should not delay treatment. In the case of chlamydia, the doctor will definitely prescribe antibiotics. Which of them will be the most effective will be shown by the results of a preliminary analysis of the sensitivity of pathogens to the active substance. The patient just needs to take the pills according to the instructions and become familiar with the side effects of these medications in advance.

What is chlamydia

Urogenital chlamydia is diagnosed more often, and the disease in 67% of cases is asymptomatic for a long time. Even with a latent infection, a sick person can infect his healthy partner. Obvious clinical signs of chlamydia in men are:

  • mucous discharge from the urethra;
  • itching and burning when urinating;
  • redness and swelling of the urethral opening.

Women are capable of transmitting chlamydia to newborns through the birth canal, so doctors recommend that before planning a pregnancy, be tested for bacterial and viral sexually transmitted infections. You can suspect something is wrong based on the characteristic symptoms of the pathology, for women these are:

  • mucous yellow or purulent mucous discharge from the vagina with an unpleasant odor;
  • itching and burning during urination;
  • increased body temperature;
  • pain in the lower abdomen.

Treatment

Chlamydia can remain in a “dormant” state for a long time and become more active when a person becomes very cold or suffers from a viral infection. Moreover, the consequences of the presence of these microorganisms in human cells can be very serious. In 40% of cases, chlamydia in men causes prostatitis, urethritis, and epididymitis. In women, this pathology provokes infertility, endometritis, inflammation of the appendages, fallopian tubes, and uterine mucosa.

In order to prevent the development of complications at the slightest symptoms, you must immediately consult a doctor and, even in the absence of characteristic signs, regularly visit a gynecologist or urologist. Treatment of chlamydia is carried out by taking antibiotics, and both sexual partners must take the medications at the same time. During this time, you should avoid sexual intercourse or use a condom.

The average course of therapy lasts from one to three weeks, then control tests must be taken three times at intervals of about a month. Chlamydia is often accompanied by a secondary infection - gonorrhea, syphilis, ureaplasmosis, gardnerellosis. In order for the treatment to be effective, the doctor chooses a combined tactic, that is, prescribes several groups of antibiotics at once.

A high level of effectiveness is achieved through intravenous or intramuscular administration of antibacterial drugs, but sometimes tablets are prescribed. In complex therapy, antifungal agents, immunomodulators, bacteriophages, digestive enzymes, and vitamin supplements can additionally be used. After recovery, the doctor will recommend undergoing a course of physiotherapy - electrophoresis, magnetic therapy, ultrasound treatment.

Antibiotics for chlamydia

Tetracyclines

Tetracycline antibiotics help to cope with the disease at the initial stage of its development, when the infection has not yet caused inflammation and there are no complications. The mechanism of operation of this group of antibacterial drugs is aimed at suppressing protein synthesis by disrupting the specific binding of bacterial RNA and ribosomes. Resistance of microorganisms to tetracycline develops slowly, so in medical practice it is not customary to prescribe small doses of such antibiotics. Popular antibacterial agents in this group:

  • Tetracycline hydrochloride;
  • Doxycycline;
  • Minocycline;
  • Unidox Solutab.

Tetracycline hydrochloride

The drug is available in different dosage forms - capsules, tablets, ointment, solutions for the preparation of injections in hermetically sealed glass containers. All medications are over-the-counter and sold in pharmacies. The main advantage of all types of drugs is their cost - you will only have to pay about 100-150 rubles for a package of tablets. Tetracycline hydrochloride has a bacteriostatic effect against gram-negative or positive microorganisms, some types of protozoa.

The medicine is prescribed for infectious and inflammatory diseases of various etiologies. An antibiotic for chlamydia is used orally in dosages of 0.25 grams every 6 hours. Intramuscular injections are used in severe forms of the disease. The drug is contraindicated in case of leukopenia, in the third trimester of pregnancy, and in cases of liver dysfunction. During treatment, side effects may develop:

  • nausea or vomiting;
  • abdominal pain;
  • stool disorders;
  • allergic reactions, rashes;
  • intestinal dysbiosis;
  • candidiasis.

Doxycycline for chlamydia

A semi-synthetic antibiotic is available in the form of capsules with a soft gelatin shell. The drug has a bacteriostatic effect and is active against aerobic cocci, gram-negative and gram-positive microorganisms. Doxycycline is prescribed for infectious and inflammatory diseases of the genitourinary and gastrointestinal tract, and for skin lesions.

The medicine, like Tetracycline hydrochloride, is inexpensive and is available without a prescription. It inhibits intestinal microflora to a lesser extent than similar tetracycline antibiotics, and is characterized by good absorption and duration of action. Adults and children weighing more than 45 kg are prescribed 200 mg of Doxycycline on the first day of treatment, then the dose is reduced to 100 mg per day. The course of therapy varies from 10 to 14 days.

The drug is not prescribed for lactose intolerance, lactase deficiency, porphyria, leukopenia. While taking pills, adverse reactions may occur from various organs and systems:

  • central nervous system – increased intracranial pressure, dizziness, papilledema;
  • organs of hearing and vision – ringing in the ears, the appearance of blind spots in the field of vision;
  • digestive tract – nausea, vomiting, constipation or diarrhea, pain in the epigastric zone;
  • allergic reactions - skin rash, itching, hyperemia, angioedema, Stevens-Johnson syndrome;
  • heart and blood vessels – pericarditis, decreased blood pressure, erythema.

Minocycline

A semi-synthetic antibiotic is available in capsule form. The active substance, minocycline hydrochloride dihydrate, affects microbial cells by inhibiting protein synthesis at the ribosome level. The drug has a wide spectrum of bacteriostatic activity. A significant disadvantage of Minocycline is its price. For a package of 20 tablets of 100 mg you will have to pay up to 1000 rubles.

The antibiotic is prescribed for the treatment of acne, skin infections, conjunctivitis, chlamydia and other infectious diseases caused by pathogens sensitive to minocycline. Capsules are taken orally, after meals, in a dosage of 100 mg (1 capsule) every 12 hours. Contraindications are similar to the drugs Doxycycline and Tetracycline hydrochloride. The following side effects may occur while taking the capsules:

  • anorexia;
  • nausea with vomiting;
  • diarrhea;
  • colitis;
  • pancreatitis;
  • vulvovaginal candidiasis;
  • baldness;
  • exacerbation of asthma;
  • dyspnea;
  • noise in ears;
  • hearing impairment;
  • change in color of the oral cavity - tongue, teeth, palate.

Macrolides

A group of antibiotics that is produced primarily in the form of tablets or suspensions. The pharmacological properties of macrolides are somewhat different from tetracycline antibacterial drugs. The effect of these drugs is aimed at disrupting protein synthesis during its transfer to the cellular structures of bacteria. Macrolides bind to the center of the ribosome, destroying peptide bonds and leading to disruption of cyclicity.

The disadvantage of this group of antibiotics is that they act more slowly than their analogues. This is due to the fact that they do not completely destroy bacteria, but stop their activity and reproduction. Resistance of microorganisms to macrolides quickly develops, so these drugs are prescribed less frequently than tetracyclines. At the same time, the risk of allergic reactions is minimal. Popular medications in this group include:

  • Azithromycin;
  • Erythromycin;
  • Macropen;
  • Vilprafen;
  • Clarithromycin;
  • Klacid;
  • Rulid.

Azithromycin

One of the most frequently prescribed drugs. It is quickly absorbed and well tolerated by patients, and is able to suppress the growth of Haemophilus influenzae. Azithromycin is prescribed not only for chlamydia, but also during the treatment of bacterial diseases of the upper respiratory tract or ENT organs. The bactericidal effect lasts up to 24 hours, so Azithromycin tablets are taken once a day, on an empty stomach, 1 capsule at a time.

The standard course of treatment for genitourinary tract infections is 3-5 days. If necessary, therapy can be repeated after three months. Azithromycin should be used with caution during pregnancy. Tablets are contraindicated in case of severe kidney or liver disorders, during lactation. Negative reactions of the body occur extremely rarely, the following are possible:

  • nausea;
  • diarrhea;
  • abdominal pain;
  • flatulence;
  • headache;
  • constipation;
  • dizziness.

Clarithromycin for chlamydia

Semi-synthetic broad-spectrum macrolide antibiotic. Clarithromycin is prescribed for the treatment of bacterial respiratory tract infections, peptic ulcers, and sexually transmitted diseases. The drug has a minimum of contraindications, including:

  • individual intolerance;
  • children under 12 years of age;
  • pregnancy and breastfeeding.

The standard daily dose for adults is 500 mg, divided into two doses. Duration of use – 7 days. Caution must be exercised during treatment of patients with renal or hepatic impairment. In case of simultaneous use of anticoagulants, it is necessary to regularly monitor the level of platelets in the blood. During treatment with Clarithromycin, vomiting, stomach pain, diarrhea, and dizziness may occur.

Klacid

Long-acting tablets inhibit protein synthesis in the microbial cell by interacting with ribosomes. Klacid is capable of accumulating in areas of inflammation and is highly effective against a large number of gram-negative and positive microorganisms, anaerobes and protozoa. The drug is prescribed for the treatment of tonsillitis, pharyngitis, skin and urinary tract infections.

Medicine for chlamydia is prescribed as a single dose of 500 mg (1 tablet) 1 time per day. In the chronic form of the disease, the dosage can be increased to 2 tablets. Take the drug with meals for 5-7 days. Treatment with Klacid is not recommended during pregnancy, breastfeeding, or renal failure. During treatment you may experience:

  • nausea;
  • vomit;
  • thrombocytopenia;
  • ventricular arrhythmia;
  • gastralgia;
  • pancreatitis;
  • transient headaches.

Fluoroquinolones

Powerful antibiotics are prescribed for severe forms of infection. Fluoroquinolones inhibit two of the most important enzymes for microbial cells - DNA gyrase and topoisomerase-4, due to which they destroy the bacterial RNA bond, the cell membrane and lead to the death of pathogenic microorganisms. This group of antibiotics is rapidly absorbed from the gastrointestinal tract (gastrointestinal tract). The maximum concentration of the drug in the blood is achieved 1-3 hours after the start of treatment.

While taking fluoroquinolones, it is important to avoid tanning and avoid sunbathing for three days after the end of therapy. For complete absorption of the active substances, it is necessary to take antibiotics at least 2 hours before meals or 6 hours after meals. Fluoroquinolone medications are available with different active ingredients, but only ofloxacin is used in the treatment of chlamydia. It can be found in medicines with the following trade names:

  • Ofloxacin;
  • Tarivid;
  • Zoflox and its analogues.

Ofloxacin

A broad-spectrum antibiotic is available in the form of tablets, capsules, eye drops, and powder for preparing solutions. Ofloxacin negatively affects the DNA of bacteria and destabilizes the vital activity of chlamydia. The drug is actively used in gynecology and urology for the treatment of sexually transmitted diseases. Somewhat less frequently, the medicine is prescribed for respiratory tract infections.

Ofloxacin antibiotics for chlamydia are prescribed in a dosage of 200-800 mg, for a course of 7-10 days. The medicine should be taken morning and evening with a full glass of water. The antibacterial agent is strictly contraindicated when the convulsive threshold is reduced as a result of injury, hypersensitivity to active components, during pregnancy and lactation. Common adverse reactions:

  • allergy;
  • tendon pain;
  • increased sensitivity to ultraviolet radiation;
  • abdominal discomfort;
  • nausea;
  • diarrhea;
  • drowsiness;
  • dizziness.

Therapy for chronic chlamydia

Treatment of diseases caused by chlamydia using one or two antibiotics in the form of tablets or suspensions is carried out only if there are no complications. When the disease becomes chronic, in order to avoid relapses, a different treatment regimen is used:

  1. Drugs for the treatment of chlamydia are prescribed in the form of injections. Preference is given to drugs with trade names - Cycloferon and Neovir. These are immunostimulating agents with activity against DNA and RNA of chlamydia. The dosage is calculated based on the patient’s weight, 4-6 mg per kilogram of body weight. Injections are given at intervals of 48 hours. The course of treatment is two weeks.
  2. After the third injection, Rovamycin is prescribed, an antibiotic from the macrolide group. The daily dose for adults is 2-3 tablets. If adverse reactions occur while taking Rovamycin, the medicine can be replaced with a safer analogue - Sumamed.
  3. In addition to immunostimulating agents and antibiotics, topical agents are used - suppositories, creams, ointments with antibacterial action.
  4. To maintain the body, vitamins in tablets may be prescribed.

Treatment of chlamydia differs in its features:

  • antibiotic dosages are quite high;
  • often several courses of different drugs are prescribed;
  • Antibacterial therapy is combined with the use of immunomodulators;
  • Antibiotics for chlamydia are prescribed in the acute phase of the disease.

The pharmacological industry offers a wide range of antibacterial agents, however, selecting a drug and calculating an adequate dosage is not easy. In each case, the doctor approaches the development of a treatment regimen individually. After all, chlamydial infection can be aggravated by other infectious processes, and the immunity of all patients is different.

The situation is further aggravated by the fact that the drug does not work during repeated treatment of chlamydia - they adapt to its formula. If the patient has previously had an infection, it is necessary to select another drug with the same effect, but a different dosage formula.

In addition to taking capsules and injections, local products are used - suppositories, ointments and creams.

If it is impossible to defeat the infection with the selected treatment regimens, the patient is tested for the bacterial strain to find out the cause of drug resistance. It takes time and costs money. However, only after laboratory testing can a suitable drug be selected.

Treatment rules

Patients must understand that treatment with antibacterial agents requires strict adherence to certain rules, otherwise the effect will not be achieved. Bacteria behave like completely intelligent creatures and try to survive in any conditions, so only strict adherence to the adjusted dosage and medication regimen will help defeat the infection.

Follow the instructions:

  • medications are taken strictly at the prescribed time;
  • after the symptoms disappear, antibiotics are continued for the time specified by the doctor;
  • the course is prescribed to both sexual partners, even if one of them has no signs of infection;
  • before starting treatment, you should pass all the required tests, on the basis of which a treatment regimen will be developed;
  • During treatment, sexual activity is completely excluded.

Remember that neglecting one of the instructions will lead to unpredictable results.

The antibiotic treatment regimen for chlamydia is the same for men and women. The dosage of drugs is determined individually.

The acute course of the disease involves three stages:

  • preparing the body to take antibiotics using immunomodulators and treating infected areas with Chlorhexidine;
  • use of prescribed medications - 7/10/14 days;
  • restoration of disturbed intestinal microflora and liver cells.

The chronic course changes the scheme of therapeutic procedures:

  1. The first stage involves the use of antibacterial agents together with immunomodulators, antioxidants and vitamin complexes.
  2. The second stage consists of using antifungal agents and enzymes.
  3. The third stage consists of taking medications that restore the liver, as well as visiting a physiotherapy room.

Thus, the chronic stage is subject to three weeks of treatment with drugs, the acute form is treated within two weeks. The duration is due to the destruction of chlamydia at all stages of development.

Description of drugs

Antibacterial drugs have either a broad spectrum of action, that is, they destroy bacteria throughout the body, or they fight specific types of microorganisms. In the case of chlamydia treatment, drugs are needed that can destroy bacteria in intracellular structures. However, chlamydia is complicated by the addition of other forms of microorganisms, which together with it attack the human reproductive organs and cause severe inflammatory processes.

Therefore, doctors prescribe a set of medications that can fight all types of genital tract infections. There are three large groups of medications for this:

  1. tetracyclines;
  2. fluoroquinolones;
  3. macrolides.

Other medications cannot have an adequate effect on these microorganisms, so they are not effective. Incorrectly selected medications will not only not have a positive effect on the course of healing, but may increase the activity of bacteria and their proliferation.

Tetracyclines

Tetracycline and, as its derivative, can overcome a fresh infection in the body, which has not yet had time to strengthen its position. Tetracycline preparations are prescribed for use at 400 mg x 4 times for a week or two. The drug doxycycline has a different regimen - 100 mg x 2 times a day.

Doxycycline is considered the most effective for chlamydia, however, it has strong side effects. These include a disorder of the functionality of the gastrointestinal tract, and the occurrence of thrush, stomatitis or glossitis. However, this applies to patients with severely weakened immune defenses.

Note! Tetracycline group drugs destroy bone structure and tooth enamel. These drugs are prescribed to children after eight years of age; they are contraindicated for pregnant women.

The next active antibiotic is Azithromycin. This drug also causes unwanted side effects associated with gastrointestinal upset, so sensitivity testing should be performed before use. If side effects increase, you should notify your doctor. In case of intolerance to the drug, the doctor will select a less effective, but safe for the body.

Unidox Solutab based on doxycycline monohydrate is best tolerated by patients, as it does not have a strong negative effect on the body. It is recommended for use by patients with gastric problems - it does not irritate the mucous membrane.

Macrolides

This group of drugs is not as toxic as tetracyclines, but no less effective. The medications are well tolerated by patients and do not have significant side effects.

Note! Macrolide antibiotics are the best treatment for chlamydia.

Among macrolides, you can choose many drugs, for example, Sumamed, Erythromycin or Macropen. Erythromycin is taken according to the regimen of 500 mg x 2 times or 250 mg x 4 times for seven days. However, this antibiotic is often poorly tolerated by patients, as it has a high degree of toxicity.

However, when using the ointment, treatment should be completed, otherwise the disturbed infection will develop more actively than during the primary infection.

Important! Antibiotics for chlamydia in men cannot be combined with alcohol and spicy foods.

Patients are more often prescribed Rovamycin, which has a minimal toxic effect on the body and effectively relieves inflammation in the lesions. This antibiotic can also be taken by pregnant women.

Sumamed is very effective in the fight against chlamydia, in addition, it also suppresses the activity of gonococci. Sumamed is also prescribed for gonorrhea. The active substance of the drug has the ability to accumulate in the affected areas, maintaining stability for up to five days. The treatment regimen involves taking the medicine one 500 mg capsule for a week or 250 mg for two weeks. This is determined by the doctor.

Fluoroquinolones

Fluoroquinolones are used when the first two groups of antibiotics for chlamydia have no effect in treatment. In this case, Ofloxacin is most often prescribed, which is used once a day at 400 mg or twice a day at 200 mg. Duration of treatment is up to nine days. The drug Ciprofloxacin is also prescribed, but less frequently - most strains show resistance to this medicinal formula.

Drugs of this group are successfully used in the treatment of mixed infections and chronic infections. However, medications should not be used to kill chlamydia in pregnant women and young children.

Antifungal agents

Since fungi are often associated with chlamydia, patients are also prescribed antifungal drugs. Fungal activity is caused by an imbalance of microflora in the body, since antibiotics destroy all bacteria indiscriminately. Fungi receive fertile soil for reproduction.

Among the antifungal agents, the following medications are widespread:

  • Trichopolum;
  • Metronidazole;
  • Fluconazole;
  • Natamycin;
  • other.

Immunomodulators

The drug Polyoxidonium is usually prescribed, which works well in the treatment of sexually transmitted infections. In addition to strengthening the immune system, Erbisol has a beneficial effect on liver cells. Immunomodulators are administered intramuscularly. Interferon group drugs and enzymes may also be prescribed.

The latter free the body from toxic substances produced by bacteria and strengthen the immune system. To support the liver, it is good to use Essentiale Forte or Karsil.

Probiotics

This group of drugs is prescribed to restore disturbed intestinal microflora. The disorder is caused by the use of potent drugs that destroy both beneficial bacteria and harmful ones. If you do not use probiotics, digestive and intestinal problems are inevitable. As a rule, the patient suffers from stool disorder - diarrhea.

List of beneficial probiotics:

  • Lactobacterin;
  • Bifiform;
  • Bifidobacterin;
  • Linux;
  • Enterol;
  • Bificol.

These drugs cannot be used independently - only after the approval of a doctor. They contain living bacteria that help in the proper processing of food.

Physiotherapy and baths

Antibiotics for chlamydia in women and men are supplemented with physiotherapy and local therapy. Baths with Chlorhexidine relieve the condition and quickly relieve symptoms. Various disinfectants are also used to administer micro-enemas.

Physiotherapy accelerates the body's recovery. For this purpose, electro- and laser phoresis, magnetic therapy, and a procedure using ultrasound are prescribed.

After completing the therapeutic course, the patient must undergo tests to ensure the effectiveness of the treatment. Analyzes include:

  • microflora test.

Chlamydia is one of the most common modern sexual diseases. It proceeds secretly, but leads to serious complications: infertility, impotence and problems with the kidneys and liver.

An additional subtlety is that in most cases, especially recently, chlamydia occurs in a chronic form. That is, the disease is there, there are no symptoms, but the risk of unpleasant consequences is increased. Fortunately, the disease can be treated, although it is quite difficult. What drugs are best suited for removing chlamydia from the body?

After entering the patient’s body, chlamydia (something between bacteria and viruses) invades the cells. It is very difficult to remove them from there, since not all drugs are able to effectively penetrate the cell membrane. There is another complicating factor - chlamydia greatly affects the immune system. This circumstance contributes to the development of other infectious diseases that occur in parallel with the main illness. Thus, in some cases, treatment must be complex, that is, deal with several diseases at once. However, this happens quite rarely.

The following groups of drugs are used to treat chlamydia in modern medicine:

  • macrolides;
  • fluoroquinolols;
  • tetracyclines.

Other drugs have not proven their effectiveness. Moreover, some of them can develop chlamydia resistance to antibacterial medications. This will not only greatly complicate therapy, but will also increase the risk of complications.

Antibiotics Review

Each of the groups of drugs discussed above differs in side effects, effectiveness indicators, and contraindications. Doctors prescribe specific medications based on the general health of patients and their sensitivity to various active substances:

  • Tetracyclines

These drugs are most effective in cases where the disease is at an early stage of development. In advanced forms, the “killer” qualities of tetracycline may not be enough. The main drugs of the group are:

  1. Tetracycline (cost about 100 rubles);
  2. Doxycycline (the drug is cheap - about 25 rubles).

The course of treatment with these drugs is designed for a period of 7 to 15 days. In this case, the daily dose of Tetracycline is 400 mg, that is, four tablets per day, and Doxycycline is 100 mg, which is equivalent to 2 tablets once a day.

  • Macrolides

These drugs are less toxic than representatives of tetracyclines, and are also able to cope with advanced chlamydia (in such a situation, the method of taking the drug differs from the generally accepted one). The list of medications is quite large:

  1. Sumamed (about 150 rubles);
  2. Klacid (costs at least 310 rubles);
  3. Vilprafen ( about 500 rubles each, you can order cheaper online);
  4. Macropen (estimated at approximately 270 rubles);
  5. Rovamycin (one of the most expensive - about 1200 rubles).

Erythromycin is considered one of the most effective. With the cost of everything 40-100 rubles this drug is able to stop the development of chlamydia even at the most advanced stages of the disease. It should be taken for a week, the dosage is calculated by the doctor. Rovamycin is a more expensive analogue of Erythromycin. It is less toxic and causes virtually no side effects, such as kidney and liver diseases.

Despite the positive qualities of Erythromycin, Sumamed has not yet been able to “outdo” any drug from this group. It quickly accumulates in the affected areas and is able to maintain a high concentration for 5 days. Even the expensive Rovamacin (about 3 days) is not capable of this. But this medicine has a drawback. It is practically useless against chlamydia species transmitted by airborne droplets.

  • Fluoroquinolols

It is possible that doctors do not yet know everything about the properties of these drugs, but they fight chlamydia, frankly, not very effectively. Moreover, the only antibiotic from this group that can have at least some effect on chlamydia is Ofloxacin (price about 50 rubles). It is prescribed for intolerance to the components of more effective drugs, as well as to enhance their effect. Please note that exceeding the daily dose of 400 mg of the drug leads to side effects such as nausea, vomiting and intestinal disorders.

Antibiotics for men and women: which ones are suitable for whom?

Treatment regimens for chlamydia in men and women are somewhat different. This is due to the peculiarities of metabolism, the structure of the genital organs and the functioning of the immune system. Moreover, the general groups of drugs remain unchanged, but the method of taking specific medications still has some differences. It is worth noting that chlamydia occurs more easily in men and is easier to treat. Optimal drugs for both sexes:

  • Sumamed;
  • Doxycycline;
  • Erythromycin;
  • Rovamycin;
  • Vilprofen.

For women the situation is somewhat different. The risk of developing complications in women is higher, especially infertility, and the immune system works differently - all side effects appear more clearly and more often.

The list of medications for girls remains the same, but the list of immunomodulators that must be taken several days before starting treatment for chlamydia is expanding. In addition, they should take antifungal medications to reduce the risk of relapse and development of infertility:

  • Diflucan (about 300 rubles);
  • Nystatin (around 100 rubles);
  • Fluconazole (10-35 rubles).

You can, of course, do without them, but then the likelihood of unpleasant consequences becomes significantly higher.

How to take antibiotics correctly?

Do not forget that any antibacterial drugs cause harm to the body. This is especially true for the immune system and microflora of the intestines and genitals. To restore the body you need to take:

  • Bifiform (400 rubles);
  • Linux (approximately 350 rubles);
  • Narine (rarely found, costs about 200 rubles);
  • Rela life (about 550 rubles).

Please note that this is an approximate list of drugs. Only a doctor can give precise recommendations. By the way, to enhance the effectiveness of antibiotics, it would be useful to take vitamin complexes. Also give up bad habits at least for the duration of the therapeutic course.

So, chlamydia can be treated, but it is quite difficult. There are a decent number of drugs, they all have their own characteristics, and you can take them strictly as prescribed by your doctor. Self-medication often leads to serious consequences, such as infertility. To avoid this, you need to regularly conduct scheduled examinations and strive to maintain your health at its best!

You can also find out by watching this video what a disease like chlamydia is, and what other methods of treating this disease are.

Chemotherapy for urogenital chlamydia in women and men is not as simple as it seems at first glance. And the selection of the optimal antibiotic against chlamydia is the key to successful treatment of the disease. Today, the pharmaceutical market is filled with many antibacterial drugs.

Some of them have a wide spectrum of action, while others, on the contrary, are specific to pathogenic microorganisms. One way or another, the choice is large, and you should navigate it correctly.

– one of the most common sexually transmitted diseases (go hand in hand with it). For this reason, special attention is paid to the treatment of this infection in men and women. Despite this, analysis of the disease in the early stages is almost impossible. In the later stages, the situation is easier, but the risk of associated complications and the difficulty of therapy increases.

The treatment regimen and choice of antibiotic depends on what form of urogenital chlamydia we are dealing with. According to one classification, there are 2 forms: infection of the lower and upper sections. The latter is also called the “complicated form”.

Selecting chemotherapy based only on these parameters is not enough. Other factors need to be taken into account:

  • Duration of infection;
  • The presence of chlamydia in a sexual partner.

The first stems from the fact that when a microorganism stays in a person for a long time, a stable relationship arises between them. In addition, prolonged infection and inadequate chemotherapy can lead to persistence of the pathogen, which requires a special approach in choosing an antibiotic.

Diagnostics

Before treating an infection, it must be diagnosed. Modern laboratory analysis can help with this. Depending on the symptoms, urine, feces are given, or a scraping is taken and research is carried out. There is a serological analysis, ELISA, PCR, bacteriological analysis (cultural method).

Each method has its pros and cons: one analysis is long, another is quick, the third does not provide information about the activity of ureaplasma, and the fourth is the opposite... One way or another, you need to get tested.

Treatment

There are many publications on, but even a modern doctor has a hard time navigating such an abundance of literature. Drugs for the treatment of chlamydia are divided into several groups: macrolides, tetracyclines and fluoroquinolones - available in tablets and injections. The name comes from their chemical structure.

It is clear that their pharmacological effect differs significantly. Other groups of antibiotics are at least powerless, since the microorganism has developed immunity to them. It is worth noting that today there is no unified method for determining the resistance of chlamydia; the accumulated data is primarily the result of clinical experience.

Treatment of lower chlamydia

Tetracyclines are the prototype of broad-spectrum antimicrobial drugs. They have a bacteriostatic effect against many G+ and G- bacteria, including various anaerobes, rickettsia, chlamydia, mycoplasma and L-forms, as well as some protozoa, such as amoebas. Equal concentrations of tetracyclines in body fluids and tissues have approximately the same antimicrobial activity.

The differences between individual drugs are not significant. Variations in clinical effectiveness are due largely to the absorption, distribution, and elimination of specific drugs. However, the sensitivity of different strains of certain types of microorganisms to drugs of this series varies.

Tetracyclines, accumulating in the body, disrupt the interaction of structures lying inside, which suppresses protein synthesis and subsequently leads to inhibition of cell growth and development. The selectivity of protein synthesis by microorganisms is explained by the low ability of mammalian cells to concentrate tetracyclines. It should be noted that tetracyclines are the main weapon in the treatment of chlamydia.

The first line drug is. Dosage form – capsules or tablets. It is used orally during meals with plenty of liquid. Prescribe 100 mg of the drug twice a day for two weeks.

The first loading dose is 200 mg. In 90-100% of cases, the infection can be cured. Combined with its low cost, this gives the drug a great advantage over tetracycline and metacycline, which are used as an alternative.

In addition to these benefits, tetracycline is highly bioavailable, better absorbed, and has a long half-life. It is a known fact that antibiotics of the tetracycline group are capable of binding to divalent metals, which significantly reduces the bioavailability of the drug.

Doxycycline does not have this disadvantage, and the patient does not need to be prescribed a special diet. Tetracyclines are contraindicated in children and pregnant women, and persons suffering from renal failure. Side effects: gastrointestinal disorders, allergies, photosensitivity.

Macrolides are considered the most effective group of antibiotics. First-line drugs include, a single use of which provides a high concentration of the drug in the tissues. In this case, the antibiotic remains in places of inflammation for more than seven days.

The use of alternative antibiotics, as injections or tablets, is allowed: spiramycin, roxithromycin, erythromycin, josamycin, clarithromycin, midecamycin or amoxicillin. Erythromycin is inferior to the presented drugs in terms of pharmacokinetics, digestibility and frequency of administration.

Side effects: similar to tetracyclines, plus liver disorders (jaundice, increased transaminase activity and cholestasis)

Fluoroquinolones are the most studied group of antimicrobial agents. Many effective drugs have been synthesized, but not all of them exhibit significant activity against Chlamydia trachomatis. Antibiotics of the III-IV generations can be noted, which have greater activity and frequency of administration compared to previous analogues.

Despite all the promise of fluoroquinolones, modern guidelines highlight one antibiotic that is most active against chlamydia - ofloxacin. Unlike others, it is 100% bioavailable. An antibiotic of 400 mg is used 2 times a day for 10 days. Other possible drugs with a similar dosage frequency: pefloxacin, lomefloxacin, levofloxacin, moxifloxacin.

After fluoroquinolone therapy, there is a high probability of relapse of chlamydia, so drugs in this group are not included in the first line. Contraindications: children under twelve years of age and pregnant women, persons with impaired renal and liver function. Side effects: gastrointestinal disorders (nausea, vomiting, diarrhea), allergic reactions, inflammation and destruction of tendons, photosensitizing effect.

Treatment of the upper sections

For chlamydia of the upper genitourinary tract, the same antibiotics are used - they take pills or give injections, but in a shorter course (up to 3 weeks). In this regard, azithromycin is very convenient, which is used in 3 courses of 1 g per week.

Chlamydia is an intractable disease for the reason that even after prolonged treatment, a recurrence of the disease is quite likely. Having passed into the chronic stage, it is able to develop immunity to a number of diseases.

This makes treatment of chlamydia in men with antibiotics useless. Antibiotics for chlamydia in women may also not bring the desired effect as a result of chlamydia mutation.

There must be therapy comprehensive and be based on the individual characteristics of the patient’s body. Moreover, other sexually transmitted and urogenital diseases can also contribute to the occurrence of inflammatory processes.

Doxycycline is effective, but in large quantities it is dangerous for the digestive system

The difficulty of treatment lies in the fact that antibiotics against chlamydia are strong only when treating the disease in the reticular stage. Still “dormant” chlamydia is not destroyed by the medicine and can develop immunity to it. For this reason, compliance with the instructions prescribed by your doctor is extremely important.

But the complexity of treatment does not negate the fact that the basis on which therapy is built is still antibiotics for the treatment of chlamydia. Only in cases where there is individual intolerance to antibiotic drugs, the doctor prescribes other methods of treatment, but such cases are quite rare.

Treatment plan

The schedule for taking medications is built depending on the clinical form of the disease. Treatment can be divided into several main stages:

  1. Preparatory. This stage lasts about a week. Preparation includes strengthening the immune system, which is carried out through the use of immunostimulating drugs. Localized sanitation of the affected areas is also carried out using Chlorhexidine.
  2. Basic. Lasts up to 2 weeks. This is the period of main treatment, when all antibiotic and antifungal agents planned for use are applied.
  3. Restorative. During this period, the body improves the functioning of the liver and intestines, in which it is helped by specially prescribed drugs to restore the microflora.

Treatment for chlamydia may differ significantly between sexual partners

However, if the disease has progressed to chronic stage and is characterized inflammation of the genital organs, then the treatment plan may change slightly:

  1. First the treatment is carried out antibiotics, antioxidants, immunostimulating drugs and vitamins. A week later, they are connected to therapy enzymes and antifungals.
  2. In another week they will start working hepatoprotectors, and the patient is sent to physiotherapeutic procedures.

What antibiotics are used to treat chlamydia?

Immunomodulators and tetracyclines

First they go immunomodulators, drugs such as Polyoxidonium with chlamydia they manifest themselves quite well. In some cases, an appointment may be made and Erbisol, which is also a hepatoprotector.

Then the antibiotics themselves come into play. from chlamydia in men and women. There are several main groups of antibiotics for this case. For not very severe lesions, most often the doctor recommends taking something from the group of tetracyclines for chlamydia.

Most Popular. However, its use if the immune system is not strong enough can cause indigestion and the appearance of thrush in women. To prevent this from happening, due attention should be paid to the previous stage of treatment.

In addition to nausea, drugs from the tetracycline group can cause disruption of the formation of bone tissue and enamel, so they are strictly contraindicated in young children, as well as pregnant and lactating women.

The choice of drugs for therapy should be entrusted to the attending physician

Also among tetracycline antibacterial drugs we can mention , Vibramycin, Dorix and others. All of them are quite effective in destroying chlamydia, however, still not as effective as macrolides.

Macrolides

Macrolides, perhaps the safest and most reliable method of therapy for chlamydia infection. Moreover, tools such as Erythromycin And Rovamycin can be used during pregnancy. Other well-known drugs in this group include Josamycin, Clarithromycin, Roxithromycin (rulid), Spiromycin, Midecamycin and Azithromycin.

For a long time, doctors have been prescribing erythromycin for chlamydia.. It is more effective than Azithromycin, however, it can cause a greater number of negative side effects, expressed in a temporary deterioration in well-being. Azithromycin, in turn, can be used against concomitant syphilis or developed gonorrheal-chlamydial infection.

Each of the drugs in the macrolide group is highly effective and also has its own dosage. It is extremely important to consult a specialist before using medications during therapy. You should also take into account possible side effects and contraindications, individual in each case.

Fluoroquinolones

Another group of drugs used to track down and kill chlamydia are drugs known as fluoroquinolones. These drugs are cheaper and less effective than macrolides and tetracyclines. However, they are able to play a supporting role in the treatment of mixed infectious diseases.

During pregnancy, you should be careful when choosing medications

The disadvantage of this group of drugs can be considered a large number of negative side effects. Also, their use is unacceptable in the treatment of pregnant women.

Fluoroquinolones are second-order drugs, which makes the use of macrolides more preferable. However, they are very useful in the treatment of resistant and chronic infections.

One way or another, before using any medications, you should consult your doctor. Chlamydia is an insidious disease that can easily recur. It is extremely important to follow the therapeutic course in its entirety and duration in order to destroy chlamydia once and for all.

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