Flemoxin Solutab belongs to the penicillin group of antibiotics. The active ingredient of the drug is amoxicillin trihydrate.
Has a wide spectrum of action:
information Flemoxin is well absorbed (93%), which is ensured by its special form, is not destroyed in the acidic environment of the stomach, and food intake does not affect its bioavailability. The drug is excreted by the kidneys, a small amount may pass into breast milk.
Flemoxin is often used in pediatrics to treat respiratory tract and ENT infections. Its release form, Solutab, is more convenient for use in children, since the medicine can be dissolved in water or chewed. The drug has a pleasant taste, which is also a plus when used in children's practice.
Indications for use are bacterial infections:
Contraindications for the use of this antibiotic are:
Carefully it should be used for renal failure, pregnancy and lactation, infectious mononucleosis and lymphocytic leukemia.
dangerous The most common side effects of penicillin antibiotics, including Flemoxin Solutab, are allergic reactions in the form of angioedema.
There are also side effects on:
The medicine has a pleasant fruity taste. The tablet can be taken in the following ways:
advice The dose of the drug is selected depending on the age, weight of the child, as well as the severity of the disease. The daily dose for children is 30-60 mg per 1 kg of body weight, divided into 2-3 doses.
Standard schemes for children of different ages:
The average treatment period is 5-7 days, for severe infections and a long course of the process - up to 10 days.
Flemoxin Solutab is available in the form of dispersible (the substance is finely ground for better dissolution and absorption) tablets of 125, 250, 500, 1000 mg per amoxicillin trihydrate.
Penicillin antibiotics have been used in the treatment of infections for decades, but have not lost their relevance due to their wide range of effects on various pathogens and effectiveness in the most common infections. One such remedy is Flemoxin Solutab. It differs from analogues with the same active ingredient in a special dosage form, which is convenient for use in childhood.
Is it allowed to give it to the smallest patients, for example, a month-old baby or a one-year-old toddler? How to take these pills correctly and what dosages are used in children? Can this antibiotic harm the body of children and what negative symptoms does its overdose cause? What drugs can replace Flemoxin Solutab if this medicine causes an allergy or turns out to be ineffective?
The drug is produced in the Netherlands in the form of tablets that can easily dissolve in water, which is why they are called dispersible and the word “solutab” is present on the medication packaging. The main ingredient of such tablets is amoxicillin. It is contained in the medicine in the form of a salt - amoxicillin trihydrate. Depending on the amount of this compound, there are Flemoxin Solutab tablets containing 125 mg and 250 mg, as well as 500 mg or 1000 mg of amoxicillin.
All of these drug options are oval white or light yellow tablets that have a score (according to this, the drug can be additionally divided into halves, which is important when treating very young children). The difference between them is the digital designation on the tablet:
Tablets are sold in blisters of 5 pieces, and one box holds 20 tablets. Only the drug containing 125 mg per tablet is additionally presented in packages of 10, 14 and 28 tablets. They come packaged either in 5 pieces or in blisters of 7 tablets.
The auxiliary components in the medicine with any dosage are the same. To ensure that the medication is dense, but at the same time easily dissolves after contact with liquid, microcrystalline cellulose and dispersible cellulose, as well as crospovidone and magnesium stearate are added to its composition. For the sweet taste of the tablet and the solution prepared from it, Flemoxin Solutab contains saccharin. The smell of the medicine is provided by vanillin, as well as tangerine and lemon flavors.
"Flemoxin Solutab" is a representative of semi-synthetic penicillin antibacterial agents, which in their structure belong to a large group of beta-lactam drugs (in addition to penicillins, it also includes carbapenems, cephalosporin antibiotics and monobactams). Such drugs have a bactericidal effect on many types of bacteria, since they are able to disrupt the synthesis of important components of cell walls called peptidoglycans. By influencing bacteria during their division and growth, Flemoxin causes their lysis (death).
The drug is active against various microorganisms, including:
The medicine may not work on Enterococcus, Proteus, Salmonella, Escherichia coli, Vibrio cholerae or Shigella, so if such a pathogen is detected, it is important to first determine the sensitivity and then begin treatment.
There are also types of bacteria that Flemoxin has no effect on at all, for example, pseudomonas or enterobacters. In addition, this medicine is ineffective against viruses, so it is not used for ARVI and other viral infections.
A swallowed tablet or a medicinal solution made from it is absorbed quite quickly and is not destroyed in the stomach (the medicine is resistant to acids). The maximum amount of amoxicillin is detected in the blood approximately two hours after administration. The diet has almost no effect on the absorption of the medication, so you can drink Flemoxin Solutab at any time of the day, without taking into account meals. Drugs are eliminated from the body through urine, so kidney disease can affect this process.
Soluble tablets are used for infectious diseases caused by bacteria sensitive to the action of amoxicillin. "Flemoxin Solutab" is in demand in the treatment of:
The medicine is used in the treatment of children of any age, so it is prescribed to babies up to one year old, preschoolers, and older children. The drug is more often prescribed to patients under 5 years of age, since soluble tablets are very convenient to give to such children.
At the same time, the use of the medication in both infants and schoolchildren or adolescents should be supervised by a doctor. Only after examination by a specialist can you be sure that such an antibiotic is needed, and also accurately calculate the dosage required for a particular disease.
Flemoxin Solutab is not prescribed to children who have shown hypersensitivity to this medicine or other amoxicillin preparations. This medication is also contraindicated if you have an allergic reaction to any beta-lactam antibiotic. Caution in the use of tablets is required by patients who are allergic to any other medications, have infectious mononucleosis, or have been diagnosed with renal failure.
A doctor's supervision is also needed when prescribing Flemoxin to children with lymphocytic leukemia or any diseases of the gastrointestinal tract.
Treatment with Flemoxin Solutab can negatively affect the patient’s digestive system, which is manifested by nausea, inflammation of the tongue, dysbacteriosis, loose stools, changes in taste, vomiting or stomatitis. In some children, the medication provokes colitis or liver damage. In rare cases, the pills cause inflammation of the kidney tissue.
The child’s nervous system may react to taking Flemoxin with confusion, insomnia, behavioral changes, headaches, anxiety and other symptoms. The use of tablets can also worsen the process of hematopoiesis, therefore, in the blood test of some children, a decrease in the number of neutrophils, platelets and other cells is detected. In addition, the drug can cause allergic reactions (for example, rhinitis, redness of the skin or urticaria).
If a child has a weakened immune system, Flemoxin can cause candidiasis. In infants, this side effect often manifests itself as thrush in the mouth: the oral mucosa turns red and itchy, and when examining the baby’s mouth, the mother may notice a white coating. In girls, the medication can provoke vaginitis, the symptoms of which are white discharge, vaginal itching, pain when urinating, and red mucous membranes.
If Flemoxin Solutab is taken incorrectly, a superinfection develops due to bacterial resistance to the drug. This complication appears:
The tablet can be swallowed and chewed, or divided into halves and washed down with water. However, in childhood, the most popular method of administration involves preparing a syrup (the tablet is ground into powder and dissolved in 20 ml of water) or a suspension (the crushed tablet is mixed with 100 ml of water). These liquid versions of the medicine have a pleasant fruity taste, making them easier for children to swallow.
The dosage of Flemoxin Solutab should be selected individually, because the calculation of the required dose is influenced by the age of the child, the severity of the infection, and the body weight of the toddler. Small patients can receive from 30 to 60 mg of amoxicillin per day per kilogram of their weight. If the disease is mild or the severity is defined as moderate, the drug is often used according to the following scheme:
In severe cases, the medicine is taken three times at a higher dose, which is determined by the doctor. The same tactics are used in case of a hard-to-reach source of infection (for example, if the middle ear is inflamed) or chronic infections with relapses. But if kidney function is impaired, the dosage is reduced taking into account blood and urine test results.
For other infections, the medication is taken as long as symptoms of the disease are present plus another 48 hours.
Too high a dose of the medicine provokes vomiting, loose stools or severe nausea, which in severe cases or at an early age can lead to dehydration. If an overdose is detected, it is recommended to rinse the child’s stomach and also give activated charcoal. In addition, in case of Flemoxin poisoning, it is important to replenish lost minerals and fluids, for which they use pharmaceutical preparations or home-prepared rehydration drinks.
In severe cases, hemodialysis is prescribed to speed up the removal of excess amoxicillin from the child’s body.
If you prescribe Flemoxin Solutab with other bactericidal drugs, their effect will mutually enhance (this is taken into account in severe cases of infection), and use with bacteriostatic antibiotics, on the contrary, can weaken the therapeutic effect. The tablets should not be used together with aminoglycosides, antacids, anticoagulants, diuretics, anti-inflammatory drugs and many other drugs.
All drugs, when used together with which Flemoxin can provoke side effects or its effect will change, are indicated in the annotation.
The purchase of Flemoxin Solutab for a child is carried out according to a prescription from a doctor, so the patient must first be examined by a doctor. The price of the drug is affected by the dosage of amoxicillin per tablet and the number of tablets in the pack. For example, a pack of Flemoxin of 20 tablets of 125 mg costs about 220 rubles, and for a pack of 20 tablets of 250 mg you need to pay 250-270 rubles.
The shelf life of Flemoxin Solutab is quite long and is 5 years from the date of manufacture. To prevent the drug from deteriorating and losing its medicinal properties, it should be stored at a temperature not exceeding 25 degrees Celsius in a dry place.
It is important that the medication is not easily accessible to children, since the sweet taste of the tablets may interest a small child, which will increase the risk of overdose.
Flemoxin Solutab is in high demand among parents of young children, since this form of amoxicillin is convenient to give to patients of any age. The drug is easily diluted with water, and the taste of the finished solution is pleasant. Judging by the reviews, the medication effectively copes with various infectious diseases (for example, otitis media, sore throat or bronchitis), helping to eliminate high fever, cough, ear pain and other symptoms. Because of the sweet taste, most children take the tablet without any difficulty.
Nevertheless, there are also negative opinions, since Flemoxin does not help some patients, which is often due to the resistance of bacteria to its main component. You can also see complaints about side effects when taking pills.
Although they are rare, sometimes babies experience nausea, a rash, or other negative reaction. As for the price of the medicine, some mothers consider it too high and buy cheaper analogues, while others call it acceptable.
If there is a need to replace Flemoxin Solutab with a similar antibiotic with the same active ingredient, Your doctor may prescribe a variety of other medications.
Unfortunately, sometimes you cannot do without antibiotics, because if left untreated, certain infectious diseases can cause a lot of complications. Of course, the modern pharmacological market offers a huge number of antibacterial drugs. And doctors often prescribe the drug “Flemoxin Solutab 1000 mg” to patients. Instructions, indications, expert reviews, cost and effective analogues - these are the points that are worth considering in more detail.
In modern medicine, the drug Flemoxin Solutab is often used. Indications, instructions, cost - these are, of course, important issues. However, first you should find out more about the composition of the drug prescribed by your doctor.
The medicine is produced in the form of white oval tablets, often with a yellowish tint. On one side there is a dividing strip, and on the other there is a digital designation of a single dose (1000 mg corresponds to the designation “236”). The tablets are packaged in blisters of 5 or 7 pieces. At the pharmacy you can purchase a package containing 2 or 4 blisters.
The main active component of the drug "Flemoxin Solutab 1000 mg", the instructions for which will be discussed below, is amoxicillin in the form of trihydrate. The tablet also contains some excipients, including crospovidone, microcrystalline and dispersible cellulose, saccharin, vanillin, magnesium stearate, and lemon and tangerine flavors.
Quite often, doctors recommend taking Flemoxin Solutab 1000 mg tablets for sore throat and other respiratory diseases. Of course, patients are interested in questions about how this medicine affects the body. What can Flemoxin Solutab 1000 mg tablets help with?
In order to answer this question, it is worth considering the basic pharmacological properties. Amoxicillin is a fairly powerful antibiotic with a wide spectrum of effects. It belongs to the group that has bactericidal properties, is resistant to acids, and therefore remains active after passing through the acidic environment of the stomach.
This substance is active against a variety of gram-positive and gram-negative bacteria, including streptococci and staphylococci, clostridia, bacilli, listeria, and salmonella. But pathogenic microorganisms that produce beta-lactamases are insensitive to this antibiotic.
How is the drug “Flemoxin Solutab” (1000 mg) absorbed by the body? The instructions contain information that the main active substance is quickly absorbed by the walls of the digestive tract. Amoxicillin is resistant to acidic environments. The maximum concentration of this compound in the blood is observed 1-2 hours after administration.
The degree of binding to plasma proteins is 20%. The antibacterial substance quickly penetrates bone tissue, sputum, mucous membranes, intraocular fluid, and bile. Amoxicillin is partially metabolized by the liver, and most of the formed substances do not have biological activity.
The active substance of the drug is excreted by the kidneys - the half-life is 1-1.5 hours (if the kidneys are healthy and functioning normally).
When do doctors prescribe the drug Flemoxin Solutab to patients? Indications for use: diseases associated with the activity of pathogenic bacteria.
The medicine is often prescribed for infectious lesions of the gastrointestinal tract and genitourinary system. In addition, the drug is effective for diseases of the respiratory system - doctors often prescribe Flemoxin Solutab tablets (1000 mg) for bronchitis, tonsillitis, tonsillitis, and pneumonia. The list of indications also includes ailments of the skin and soft tissues.
It is worth understanding that you should not use antibiotics without permission. Only the attending physician, after familiarizing himself with the clinical picture and test results, will be able to draw up a treatment regimen with Flemoxin Solutab (1000 mg). The instructions for use contain only general information.
The medicine is taken regardless of food. The tablet can be swallowed completely with a glass of water, or chewed first. It is possible to grind the tablet into a powder, which can then be dissolved in a small amount of liquid (about 100 mg) - this will result in a suspension with a pleasant citrus taste.
In what quantities should I take the drug “Flemoxin Solutab 1000 mg”? The dosage is determined individually. As a rule, for mild forms of bacterial diseases, adult patients are recommended to take 500 mg of amoxicillin three times a day (half a tablet). If we are talking about more severe forms of infection or recurrent diseases, then the dose can be increased to 1 g of antibiotic (one tablet) three times a day. For uncomplicated forms of gonorrhea, patients are prescribed a single dose of 3 g of amoxicillin.
The duration of therapy depends on individual factors. Typically, treatment lasts about 5-7 days. In some cases, the doctor may extend therapy for a few more days.
Can all patients take the drug Flemoxin Solutab (1000 mg)? The instructions contain information about the presence of contraindications. You should definitely familiarize yourself with their list before starting therapy.
Adverse reactions when taking tablets are rarely recorded. However, this possibility exists, so it is worth familiarizing yourself with the list of complications.
If during treatment you feel a deterioration, you should immediately report this to your doctor. Sometimes side effects go away after dosage adjustment.
Cases of overdose are rarely recorded, since even large doses of the drug are well tolerated by the human body. However, if you take too many tablets at once, complications may occur. In such cases, patients experience disorders of the digestive system - nausea, severe vomiting, diarrhea. Severe diarrhea can lead to serious electrolyte imbalances and dehydration. That is why the victim must be urgently taken to the hospital.
As a rule, the patient first needs gastric lavage. After this, doctors prescribe sorbents that can bind and remove from the body the remains of the drug that are still in the digestive system. Next, you need to take measures to restore the water and electrolyte balance. Serious, irreversible complications in this case are practically not recorded.
Information about the rules of use and possible complications is, of course, very important. But for many patients, one of the key questions is how much the drug “Flemoxin Solutab” 1000 mg will cost. The price, of course, will vary depending on the pricing policy of the pharmacy, manufacturing company and other factors. For a package of 20 tablets you will have to pay about 500-600 rubles.
This medicine is often used to fight infectious diseases. However, it is not suitable for all patients. What to do in such cases? Is it possible to replace the drug with something?
The modern drug market offers a lot of substitutes. For example, pharmacies sell Amoxicillin with the same active ingredient (the name itself indicates this). This medicine can be purchased in the form of tablets, suspensions, drops and capsules, however, the maximum dose is 500 mg of antibiotic. Analogs include the drug “Amoxin”, as well as capsules “Iramox”, “Graximol”, and “Gramox” powder. Of course, choosing a safe and effective medicine is the task of the attending physician. Using antibiotics without permission is strictly prohibited.
Of course, people who, for one reason or another, have to take the drug are interested in questions about what Flemoxin Solutab tablets (1000 mg) actually are. Reviews about it are mostly positive. The effect of therapy is confirmed by both doctors and their patients. Amoxicillin really copes with infectious diseases of the respiratory tract, skin, and excretory system. Improvement in the patient's condition can be observed within a few days after the start of therapy.
The occurrence of side effects is actually recorded extremely rarely, and the list of contraindications is not that long. An undoubted advantage of the drug is its affordable cost - prices for medications containing the same amoxicillin are often much higher. The drug is really good, which explains the degree to which it is in demand in modern medical practice.
Flemoxin Solutab®
Amoxicillin
Dispersible tablets 125 mg, 250 mg, 500 mg, 1000 mg
One tablet contains
active substance: amoxicillin in the form of amoxicillin trihydrate
125 mg, 250 mg, 500 mg, 1000 mg
Excipients: dispersible cellulose, microcrystalline cellulose, crospovidone, vanillin, tangerine flavor, lemon flavor, saccharin, magnesium stearate.
Tablets are white to light yellow, oval in shape with the company logo and digital designation on one side (125 mg - “231”, 250 mg - “232”, 500 mg - “234”, 1000 mg - “236”) and risky, on the other side.
Antimicrobial drugs for systemic use. Beta-lactam antibacterial drugs. Broad-spectrum penicillins. Amoxicillin.
Code ATXJ01CA04
Pharmacokinetics
Suction
After oral administration, amoxicillin is absorbed quickly and almost completely (about 93%), and is acid-stable. Food intake has virtually no effect on the absorption of the drug. The maximum concentration of the active substance in plasma is observed after 1-2 hours. After oral administration of 500 mg of amoxicillin, the maximum concentration of the active substance of 5 mcg/ml is observed in the blood plasma after 2 hours. When the dose of the drug is increased or decreased by 2 times, the maximum concentration in the blood plasma also changes by 2 times.
Distribution
About 20% of amoxicillin is bound to plasma proteins. Amoxicillin penetrates well into mucous membranes, bone tissue, intraocular fluid and sputum in therapeutically effective concentrations. The concentration of amoxicillin in bile exceeds its concentration in blood plasma by 2-4 times. In amniotic fluid and umbilical vessels, the concentration of amoxicillin is 25-30% of its level in the blood plasma of a pregnant woman. Amoxicillin does not penetrate the blood-brain barrier well; however, with inflammation of the meninges, the concentration in the cerebrospinal fluid is about 20% of the concentration in the blood plasma.
Metabolism
Amoxicillin is partially metabolized in the liver; most of its metabolites do not have microbiological activity.
Removal
Amoxicillin is eliminated primarily by the kidneys, about 80% by tubular excretion, 20% by glomerular filtration. In the absence of renal dysfunction, the half-life of amoxicillin is 1-1.5 hours. In premature infants, newborns and children under 6 months. - 3-4 hours
Pharmacokinetics in special clinical situations
The half-life of amoxicillin does not change with impaired liver function.
Pharmacodynamics
Flemoxin Solutab® is a bactericidal, acid-resistant, broad-spectrum antibiotic from the group of semisynthetic penicillins. Active against gram-positive and gram-negative microorganisms, such as Streptococcus pyogenes, Streptococcus pneumoniae, Clostridium tetani, Clostridium welchii, Neisseria gonorrhoeae, Neisseria meningitidis, Staphylococcus aureus(not producing beta-lactamases), Bacillus anthracis, Listeria monocytogenes, Helicobacter pylori. Less active in relation to Enterococcus faecalis, Escherichia coli, Proteus mirabilis, Salmonella typhi, Shigella sonnei, Vibrio cholerae. Not active against microorganisms producing beta-lactamases, Pseudomonas spp.., indole-positive Proteus spp., Serratia spp., Enterobacter spp.
respiratory infections
infections of the genitourinary system
infections of the gastrointestinal tract
skin and soft tissue infections
The drug is taken orally before or after meals. The tablet can be swallowed whole, divided into pieces or chewed with a glass of water, and can also be diluted in water to form a syrup (20 ml) or suspension (100 ml) with a pleasant fruity taste.
The dose is set individually, taking into account the severity of the disease and the patient’s age. When infectious and inflammatory diseases of mild and moderate severity It is recommended to use the drug according to the following scheme:
INadults and children over 9 years old prescribed 500 - 750 mg 2 times / day or 375 (one and a half tablets of 250 mg) - 500 mg 3 times / day. The minimum single dose is 375 mg (one and a half tablets of 250 mg), the maximum daily dose is 1500 mg.
Children from 3 to 9 years old prescribed 375 mg (one and a half tablets of 250 mg) 2 times a day or 250 mg 3 times a day. The minimum single dose is 250 mg, the maximum daily dose is 750 mg.
Children aged 1 to 3 years prescribed 250 mg 2 times a day or
125 mg 3 times/day. The minimum single dose is 125 mg, the maximum daily dose is 500 mg.
The daily dose of the drug for children is 30-60 mg/kg/day, divided into 2-3 doses. The minimum single dose is 10 mg/kg, the maximum daily dose is 60 mg/kg.
When treating severe infections and diseases such as acute otitis media, a three-time dose is preferable.
At chronic diseases, recurrent infections and severe infections dose the drug may be increased: adults prescribed 750 mg - 1 g 3 times/day, minimum single dose 750 mg, maximum daily dose 3 g; dkids 60 mg/kg/day, divided into 3 doses, minimum single dose 20 mg/kg, maximum daily dose 60 mg/kg.
For acute uncomplicated gonorrhea, 3 g of the drug is prescribed in 1 dose in combination with 1 g of probenecid.
For patients with impaired renal function with a creatinine clearance of 15-40 ml/min, the interval between doses is increased to 12 hours; with CC below 10 ml/min, the dose of the drug is reduced to 15-50%; for anuria - maximum dose 2 g/day.
In case of mild to moderate infections, the drug is taken for 5-7 days. However, in infections caused by Streptococcus pyogenes, The duration of treatment should be at least 10 days.
When treating chronic diseases and severe infections, the dose of the drug should be determined by the clinical picture of the disease. The drug must be continued for 48 hours after the symptoms of the disease disappear.
Often
Allergic skin reactions (maculopapular rash)
Rarely
Change in taste
Nausea, vomiting, diarrhea, anal itching
Erythema multiforme exudative (Stevens-Johnson syndrome)
Pseudomembranous and hemorrhagic colitis
Very rarely
Interstitial nephritis
Possible
Agranulocytosis, neutropenia, thrombocytopenia, hemolytic anemia
Specific maculopapular rash
In some cases
Moderate increase in the activity of “liver” transaminases
Anaphylactic shock
Angioedema
Hypersensitivity to the drug and other beta-lactams
antibiotics
Infectious mononucleosis and lymphocytic leukemia
Probenecid, phenylbutazone, oxyphenbutazone and, to a lesser extent, acetylsalicylic acid, indomethacin and sulfinpyrazole suppress tubular secretion of penicillins, prolonging plasma half-life and increasing plasma levels. Amoxicillin is used in therapy in combination with probenecid.
Bactericidal antibiotics (including aminoglycosides, cephalosporins, vancomycin, rifampicin) have a synergistic effect when taken simultaneously. Antagonism is possible when taken with some bacteriostatic drugs (for example, tetracyclines, macrolides chloramphenicol, sulfonamides). Concomitant use with estrogen-containing oral contraceptives may lead to a decrease in their effectiveness and an increased risk of developing acyclic bleeding. Co-administration with allopurinol increases the frequency of skin reactions.
A history of erythroderma is not a contraindication for the use of Flemoxin Solutab®.
Cross-resistance with penicillin drugs and cephalosporins is possible.
As with other penicillin drugs, superinfection may develop.
The appearance of severe diarrhea, characteristic of pseudomembranous colitis, is an indication for discontinuation of the drug.
During combination therapy with metronidazole, you should not drink alcohol.
Use in pediatrics
Pregnancy and lactation
Use during pregnancy is possible after a medical assessment of the risks/benefits of treatment.
In small quantities, the drug is excreted in breast milk, which can lead to the development of sensitization phenomena in the child.
Effect of the drug on the ability to drive vehicles and other potentially dangerous mechanisms
Does not affect
Symptoms: nausea, vomiting, diarrhea; water-electrolyte imbalance.
Treatment: gastric lavage, activated carbon, saline laxatives; measures to restore water and electrolyte balance.
5 tablets each in a blister pack made of polyvinyl chloride film and aluminum foil. 4 contour packages together with instructions for medical use in the state and Russian languages are placed in a cardboard box.
Store in a place protected from light, at a temperature not exceeding 25 °C.
Keep out of the reach of children!
Do not use after expiration date!
On prescription
Astellas Pharma Europe B.V., Silviusweg 62, 2333 WE, Leiden, The Netherlands
Address of the organization that accepts claims from consumers regarding product quality on the territory of the Republic of Kazakhstan
Representative office of Astellas Pharma Europe B.V. in the Republic of Kazakhstan
From this medical article you can familiarize yourself with the drug Flemoxin Solutab. The instructions for use will explain in what cases the medicine can be taken, what it helps with, what are the indications for use, contraindications and side effects. The annotation presents the forms of release of the drug and its composition.
In the article, doctors and consumers can only leave real reviews about Flemoxin Solutab, from which you can find out whether the medicine helped in the treatment of sore throat, sinusitis and other infections in adults and children. The instructions list analogues of Flemoxin Solutaba, prices of the drug in pharmacies, as well as its use during pregnancy.
Flemoxin Solutab is an antibacterial and bactericidal drug. Instructions for use for children and adults recommend taking tablets of 500, 1000, 125 and 250 mg for the treatment of infectious and inflammatory diseases caused by microorganisms sensitive to the action of amoxicillin: infections of the skin and soft tissues; infections of the digestive, respiratory and genitourinary systems.
The dosage form of the antibiotic Flemoxin Solutab is dispersible tablets 125, 250, 500 or 1000 mg. Sold in blisters of 5 or 7 pcs.
Active ingredient: amoxicillin – 125, 250, 500 or 1000 mg (in the form of amoxicillin trihydrate).
Flemoxin Solutab is a broad-spectrum semi-synthetic penicillin antibiotic. It is a 4-hydroxyl analogue of ampicillin. Has a bactericidal effect.
Active against aerobic gram-positive and gram-negative bacteria. microorganisms that produce penicillinase are resistant to amoxicillin, the active substance of the drug Flemoxin Solutab. Instructions for use for children and adults indicate that in combination with metronidazole, the antibiotic is active against Helicobacter pylori. Amoxicillin is believed to inhibit the development of Helicobacter pylori resistance to metronidazole.
Cross-resistance exists between amoxicillin and ampicillin. The spectrum of antibacterial action expands with the simultaneous use of amoxicillin and the beta-lactamase inhibitor clavulanic acid.
This combination increases the activity of Flemoxin Solutab against Bacteroides spp., Legionella spp., Nocardia spp., Pseudomonas (Burkholderia) pseudomallei. However, Pseudomonas aeruginosa, Serratia marcescens and many other gram-negative bacteria remain resistant.
Indications for use of the drug include infections:
Flemoxin Solutab is intended for oral use only. The tablets should be taken before, during or after meals. They can be swallowed whole, chewed with a glass of plain water, or divided into pieces. You can also dilute the tablet in water to form a suspension (100 ml) or syrup (20 ml), which has a pleasant fruity taste.
The dosage regimen of Flemoxin Solutaba is set individually for each patient. This takes into account the severity of the disease, the sensitivity of the pathogen to the drug, and the age of the patient.
For infectious-inflammatory pathologies of moderate and mild severity, it is advisable to use tablets according to the following scheme: 
The total daily dose of the drug for children (including children under 1 year of age) should be 30-60 mg/kg body weight per day, divided into 2-3 doses.
Taking the pills must be continued for 48 hours after the signs of the disease disappear.
The use of Flemoxin Solutab during pregnancy and lactation is possible if the expected benefit of therapy for the mother outweighs the risk of side effects in the fetus and infant. Amoxicillin is excreted in small quantities into breast milk, which can lead to the development of sensitization phenomena in an infant.
It is used in children according to indications according to the dosage regimen (including infants and newborns).
Due to the high likelihood of developing exanthema, which has a non-allergic etiology, in infectious mononucleosis and lymphocytic leukemia, Flemoxin Solutab is prescribed with caution.
For mild diarrhea that appears while taking the drug, antidiarrheal drugs that reduce intestinal motility should not be used. The presence of erythroderma in the medical history is not a contraindication for therapy.
Due to the growth of microflora insensitive to the action of Flemoxin Solutab, superinfection may develop (appropriate changes will be required in antibacterial therapy).
Probenecid, phenylbutazone, oxyphenbutazone, diuretics, allopurinol, NSAIDs, and to a lesser extent, acetylsalicylic acid and sulfinpyrazone suppress the tubular secretion of penicillins, which leads to an increase in T1/2 and an increase in the concentration of amoxicillin in the blood plasma.
Bactericidal antibiotics (including aminoglycosides, cephalosporins, vancomycin, rifampicin) exhibit synergism when taken simultaneously. Antagonism is possible when taken with some bacteriostatic drugs (for example, chloramphenicol, sulfonamides).
Analogs in composition include:
The average price of Flemoxin Solutab in Moscow is 307 rubles. In Kyiv you can buy an antibiotic for 119 hryvnia, in Kazakhstan - for 1266 tenge. In Minsk, pharmacies offer tablets for 7-9 bel. rubles Dispensed from pharmacies with a prescription.
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The manual discusses programs of domestic and foreign authors that are used in the work...
How often do we see this monster with goat horns when we lay out Tarot cards. "Devil" is the personification of hell...