How is a test for ureaplasma carried out in women? Why do you need a test for ureaplasma in women? Positive test for ureaplasma in women

  1. Ureaplasmosis is indeed a disease that is prone to chronicity.
  2. When diagnosing ureaplasmosis, false-positive responses are often encountered, which leads to overdiagnosis and false responses when monitoring treatment.
  3. Chronic ureaplasmosis requires complex treatment.
  4. Ureaplasma is a conditionally pathogenic microorganism (for some women it is the normal flora of the vagina). Symptoms of ureaplasma

From the moment of infection with ureaplasmosis until the first symptoms of ureaplasmosis appear, it usually takes from 4 days to a month. However, the latent period of ureaplasmosis can last longer, sometimes reaching several months in duration. During the latent period, a person is already a carrier of ureaplasmosis himself, and can become a source of infection for his sexual partners. After the end of the incubation period, that is, on average, a month after infection, the first symptoms of ureaplasmosis appear. It should be noted that ureaplasmosis often manifests itself with mildly noticeable symptoms, to which the patient may not pay attention, and sometimes does not manifest itself at all. The asymptomatic development of ureaplasmosis is especially typical for women who can live with the infection for decades without knowing it. Moreover, just as in the case of mycoplasmosis, ureaplasmosis does not cause any specific symptoms and the symptoms of ureaplasmosis completely coincide with the symptoms of any other inflammatory infections of the genitourinary tract.

Symptoms of ureaplasmosis in men:

Nongonococcal urethritis is the most common manifestation of ureaplasmosis in men.

  • frequent absence of subjective symptoms (cramps, pain when urinating);
  • small, cloudy discharge from the urethra, mainly after prolonged urinary retention (in the morning);
  • tendency to a sluggish, recurrent course (discharge from the urethra spontaneously disappears for a certain period of time, then appears again);
  • Orchiepidymitis - inflammation of the epididymis and testicle occurs against the background of sluggish urethritis.

Symptoms of ureaplasmosis in women:

  • cervicitis - the diagnosis of cervicitis is often established only on the basis of the results of a microscopic examination of a smear from the cervical canal;
  • frequent, painful urination;
  • vaginal discharge, colpitis - very often U.urealyticum is found in bacterial vaginosis
  • pain in the lower abdomen, the appearance of endometritis, myometritis, salpingo-oophoritis - a rather rare manifestation of ureaplasma infection. The patient, as a rule, is unaware of his illness for a long time. The latent period averages about a month; after this period, rather sparse symptoms appear.

Ureaplasma and pregnancy

Ureaplasmosis is one of those infections for which a woman needs to be examined when planning a pregnancy. This needs to be done for two reasons. Firstly, even a small amount of ureaplasma in the genitourinary tract of a healthy woman during pregnancy (which is a significant stress for the immune system of the expectant mother) can revive and lead to the development of ureaplasmosis. Secondly, it is impossible to treat ureaplasma during pregnancy, especially in the early stages, when it is most dangerous for the fetus and can lead to miscarriage, due to the fact that the effect of antibiotics on the fetus in the first weeks of pregnancy can be dangerous. Based on this, when planning a pregnancy, a woman who cares about her health and the health of her unborn baby needs to think about how to “remove” ureaplasma from the body in a timely manner.

As for the fetus, during pregnancy infection occurs in the rarest cases, since the fetus is reliably protected by the placenta, which does not allow ureaplasma to pass through. However, in approximately half of the cases, the baby becomes infected while moving through the infected birth canal during childbirth. In such cases, ureaplasma is detected on the genitals of infants, most often in girls, or in the nasopharynx of infants, regardless of gender. If during pregnancy a woman nevertheless becomes ill with ureaplasmosis, then she needs to consult a doctor who is monitoring her pregnancy as soon as possible. In order to avoid infection of the child during childbirth and reduce the risk of premature birth, a pregnant woman with ureaplasmosis after 22 weeks of pregnancy is prescribed antibiotic treatment, which is selected by a specialist taking into account the patient’s pregnancy. In addition, a pregnant woman with ureaplasmosis is prescribed drugs that strengthen the immune system in order to minimize the risk of secondary infections. At the present stage, medicine is already successfully coping with ureaplasmosis in pregnant women, and the presence of ureaplasma during pregnancy is not an indication for artificial termination of pregnancy.

Tests for ureaplasmosis

Diagnosis of ureaplasmosis is often difficult for several reasons. First of all, ureaplasmas can constitute the natural biological environment of the genitourinary tract of a completely healthy person and are capable of provoking pathological processes only under a certain set of circumstances. Therefore, the existence of ureaplasma in the human genitourinary tract does not indicate the presence of ureaplasmosis. The greatest importance in diagnosing ureaplasmosis is not so much the fact of the presence or prolonged presence of ureaplasmas in the genital tract, but rather their number and distribution in parts of the genitourinary tract. Only if ureaplasma is found in large quantities, and the patient has all the external signs of the disease, does the doctor have the right to make a diagnosis of “ureaplasmosis” and talk about the need for treatment of ureaplasma.

To diagnose ureaplasmosis, a specialist always uses a combination of diagnostic methods. It is possible to determine whether there is ureaplasma in the body using special tests. Based on the results of a general smear, one can only assume the presence of ureaplasma. To determine the pathogen, more accurate examination methods are used - PCR and bacterial culture. Quite often (up to 75-80% of cases) simultaneous detection of ureaplasma, mycoplasma and anaerobic microflora (gardnerella, mobiluncus) is noted.

Methods for diagnosing urepalasma

  • Culture study on selective media. Such an examination allows you to determine the culture of the pathogen within 3 days and separate ureaplasmas from other mycoplasmas. The method makes it possible to determine the sensitivity of isolated pathogens to various antibiotics, which is extremely important given the fairly common antibiotic resistance today. The specificity of the method is 100%. This method is used for the simultaneous detection of Mycoplasma hominis and Ureaplasma urealyticum.
  • Detection of pathogen DNA by PCR. The examination allows one to detect the pathogen in a scraping from the urogenital tract within 24 hours and determine its species.
  • Serological tests. They can detect the presence of antigens and specific antibodies to them in the blood. They can be useful in cases of recurrent disease, complications and infertility.
  • Using the ELISA method (enzyme-linked immunosorbent assay) - the presence of antibodies to ureaplasma.

Treatment of ureaplasma

Treatment of ureaplasma includes complex procedures depending on the location of the inflammatory process. In general, antibacterial agents are used that are aimed at destroying the infection; immunomodulators that activate the body's defenses; medications that reduce the risk of side effects when taking antibiotics. A specific treatment regimen for ureaplasma can only be determined by a specialist who has all the information about the patient (examination, anamnesis, tests. Ureaplasma is resistant to beta-lactam antibiotics (penicillins and cephalosporins), due to the fact that they lack a cell wall, and sulfonamides, since these microorganisms do not produce acid. In the treatment of ureaplasma infection, those antibacterial agents that affect the synthesis of protein from DNA, that is, those that have a bacteriostatic effect, can be effective. The question of the influence of ureaplasma on the reproductive function of people remains open. Meanwhile, female infertility can be also explained by inflammatory processes in the genital area infected with ureaplasma, which lead to a change in the passage of the egg into the uterine cavity. Male infertility can be explained, firstly, by inflammatory processes, and secondly, by the influence of ureaplasma on spermatogenesis. Localization of ureaplasma on the surface of spermatozoa can disrupt their mobility, morphology and chromosomal apparatus.

Testing for ureaplasma in women has become a source of controversy in scientific medical circles. Some insist on the insidiousness of the microorganism, the hidden threat of delayed illnesses and breakdowns, complicated pregnancy, even miscarriage. Some make good money by exploiting people's fear for their health. Others tend to rely only on facts confirmed by experiments, shifting the responsibility of choice to the patient, and question the clinical significance of the infection itself.

Let's try to separate commercial myths from medical data and talk about the true danger of ureaplasma so that people understand what they are facing.

Information about ureaplasma

Information about ureaplasma

The microorganism belongs to the family of mycoplasmas - tiny bacteria that do not have their own cell wall, which makes them slightly vulnerable to most antibiotics. Mycoplasmas (mollicutes) occupy an intermediate position between viruses and unicellular microbes.

The fact that ureaplasma is found in the majority of women (60 - 80%) and a significant part of the male sex (45%) allows us to consider the microbe part of the normal microflora. But when local immunity fails, the bacterium tends to grow rapidly, provoking ureaplasmosis.

Although this diagnosis is not included in the list of the International Classification of Diseases, it is considered when, in the presence of inflammation, no more significant pathogenic factors have been identified. Ureaplasma and mycoplasma as a specified pathogen are included in the diagnoses:

  • Cervicitis (code N72.0 + B96.8);
  • Urethritis (code N34.0 + B96.8);
  • Vaginitis (code B07.0 + B96.8).

Given the recent start of research into ureaplasma and its pathogenic role, the study of the microorganism continues. Two biologically significant variants of ureaplasma have been found: urealyticum and parvum, with the biovar urealyticum being less common and more dangerous. A person can be a carrier of one of them, or both at the same time. Mycoplasmas are considered to be opportunistic flora that can cause harm only to people with immune deficiency.

Today there is a consensus: the very fact of detection of ureaplasma parvum and urealyticum in a woman in tests is the norm; if the numbers are insignificant, there are no complaints. Treatment for the only reason - a positive test - is not carried out.

If the disease is present, and laboratory data do not show other pathogens, except for an increased level of ureaplasma, a diagnosis of “ureaplasmosis” is made. Treat with broad-spectrum antibiotics (tetracycline, erythromycin, doxycycline, ofloxacin, azithromycin), based on the results of sensitivity tests.

Tetracycline
Erythromycin Doxycycline Ofloxacin
Azithromycin

Important! The picture is different before a planned pregnancy or during its course. A woman whose tests have shown the presence of ureaplasma has the right to know that hormonal changes can reduce local immune defense. This provokes the proliferation of pathogens suspected of causing miscarriage, premature fetus, and pneumonia of the newborn.

How is ureaplasma detected?

Today, precise laboratory methods together make it possible to identify with high reliability both the ureaplasma itself and the antibodies to it produced by the immune system. Any single method will show a contradictory picture, so a set of tests is prescribed. Responsible doctors simultaneously take tests for ureaplasma in women, which include:

  • Serological examination of blood serum (IgG, IgA);
  • Microbiological analysis (culture with antibiotic sensitivity control);
  • PCR (polymer reaction) technique for detecting pathogen DNA.

For serology, venous blood is taken, for microbiology and PCR - biological fluids (urine, in men also prostate secretions, sperm), epithelial cells of the genitourinary tract.

Note! Before taking the test, a woman needs to know that the menstrual cycle affects hormonal levels and the balance of microflora. To avoid getting a false positive answer, you should, on the recommendation of your doctor, choose the optimal time for collecting the material.

It is advisable to repeat the examination after 2 weeks to monitor the dynamics of microorganism growth.

After antimicrobial therapy, it is important to monitor whether the disease is cured - if the result is negative, ureaplasma and other bacteria are excluded as a pathogenic factor.

Problems in interpreting tests for ureaplasma

Problems in interpreting tests for ureaplasma

Practicing doctors are of the opinion that the contamination rate is up to 104 CFU per 1 ml acceptable, above - considered dangerous and subject to treatment. There is no convincing data on such figures in the scientific literature; there are only assumptions.

The problem of interpreting tests for ureaplasma remains unresolved - each doctor takes his own responsibility, analyzing the clinical picture of each individual patient, and makes an informed decision about the advisability of fighting the microbe.

An honest doctor has a responsibility to inform the patient of the risks revealed by medical research, but at the same time refrain from trying to intimidate and prey on his gullibility. Some people are guilty of commercial temptation, attributing mythical horrors to mycoplasmas, thereby inclining the patient to expensive, often useless, treatment.

Information about the dangers of ureaplasma

What are mycoplasmas really guilty of, what are they suspected of, based on research results?

Some data on the impact of Ureaplasma urealyticum contamination on women's health concern:

  • Inflammation of the urogenital tract, uterus, genital appendages;
  • Pathological course of pregnancy;
  • Miscarriages;
  • Cases of ectopic pregnancy;
  • Formations of adhesions in the pipes;
  • Low birth weight;
  • Pneumonia of the newborn;
  • Infertility.

The male sex is at risk of urethritis, impaired spermatogenesis (sedentary and immobile sperm), prostatitis, and damage to the musculoskeletal system.

Arguments about the relative harmlessness of mycoplasmas

Examining healthy women who have no complaints or clinical signs of the disease, ureaplasma parvum is found in tests in 80 - 90% of women of reproductive age, urealyticum - in 30%. In this case, women carry the fetus normally and give birth to healthy babies.

Analyzing individual data on the dangers of mycoplasmas, it is difficult to trace the cause-and-effect relationship. Indeed, in patients with the listed ailments, increased contamination with urealyticum was detected, but its role as a trigger is not yet clear.

Note! It is fair to talk about the risks for persons with impaired immune defense function, microflora imbalance, and immunodeficiency conditions. Such people must be treated for ureaplasmosis.

Regarding the advisability of treating asymptomatic ureplasma, preventive therapy is not practiced in the world. Treatment is prescribed exclusively based on obvious indicators - the presence of complaints, obvious symptoms, positive laboratory results.

Important! If urethritis, cervicitis, or vaginitis is diagnosed, therapy is mandatory, even when the pathogen is not identified.

During pregnancy, if a sexually transmitted infection is detected that is included in the list of TORCH infections (dangerous to the fetus), then when the pathogen is destroyed with antibiotics, ureaplasma will also suffer, since it is sensitive to the prescribed drugs.

Mycoplasmas themselves are not currently included in the list of TORCH infections, so they should not be treated only when the test is positive during pregnancy, especially if the pregnancy proceeds without problems in the genital organs. The negative effect of therapy may outweigh the therapeutic result. There is evidence that antibiotics during pregnancy do not protect against premature birth.

Responsibility of choice for treatment of ureaplasmosis

Responsibility of choice for treatment of ureaplasmosis

I was diagnosed with ureaplasmosis.
Please tell me whether this infection could have occurred during oral sex, and if so, should oral sex be avoided?
How to protect yourself from this infection (except using a condom)

Without a condom there is no way to protect yourself from infection. Of course, there are contraceptives that have a bactericidal effect: Pharmatex, Patetex oval, but only a high-quality condom has 100% protection.

It is not transmitted through oral sex.. There is a small chance of contact transmission - through a shared sheet, but the main route is ordinary sexual intercourse.

If there is already an infection, there is no point in protecting yourself from it. Both partners are still treated at the same time, even if the second is not diagnosed with the disease. This is a general rule. During treatment, be sure to use a condom. Otherwise, partners re-infect each other, and treatment becomes useless.

THEY WERE DIAGNOSED - ureaplasmosis and gardnerellosis, during examinations using the PCR method, but the usual analysis did not show the presence of any infection, I underwent 2 courses of treatment, but the situation is the same. The second doctor says that there is no need to pay attention to PCR, because this test is too sensitive. I don’t know whether I should continue treatment or calm down. And will this interfere with future pregnancies?

If the usual analysis does not show the classic signs of gardnerellosis: key cells. small rod and coccal or mixed flora, no need to treat. If PCR repeatedly detects ureaplasma several times, then the point is not in the high sensitivity of the method, but in the fact that ureaplasma really exists. If you are planning a pregnancy, you need to undergo treatment. Both (all) partners, the same antibiotics, with the addition of immune drugs, for a long time, using a condom... And be tested no earlier than a month after the end of treatment. Ureaplasma is quite resistant to treatment. You need to change the drug and try again

I was diagnosed with ureaplasma. My husband and I have been living together for six years (since 1994), and we have not cheated on each other, that is, we could not become infected through sexual contact. But I had two sexual intercourse eight years ago. Could this infection appear after so many years?

Firstly, the infection could appear after 8 years.

Secondly, my husband may also have ureaplasma for a long time.

Thirdly, you could get ureaplasma from your mother during childbirth or in childhood through household means.

Fourthly, detection of ureaplasma in a smear is not a manifestation of infection. What else worries you? There are frequent cases of the existence of ureaplasma in healthy women.

Fifthly, there are cases of incorrect, false-positive diagnosis, i.e. in fact, there is no ureaplasma.

Therefore, it is necessary not to find out who infected whom, but to solve the problem. If there are no complaints, repeat the analysis. If something worries you or you are planning a pregnancy in the near future, treat ureaplasma together with your husband (you don’t have to check him, infections in sexual partners are always the same).

After getting tested, I was diagnosed with (Ig G) CHLAMYDIOSIS 0.563 weakly positive. with def=0.242, MYCOPLASMOSIS 0.348 - sex with def=0.273 and UREAPLASMOSIS 0.510 - sex with def=0.271. What do these numbers mean, and how serious is this result? I was prescribed REAFERON 1 ml IM for 10 days, TIMELAN 1 tablet/day for 14 days, METRANIDAZOLE for 5 days, and BETADINE suppositories for 14 days. How effective and safe is this treatment? Is it possible to cure Chlamydia in one course of treatment, or will it be necessary to repeat it?

If the numbers you gave are IgG indicators for all three infections, then they only mean that you suffered them in the past and you have antibodies to them. You also need to take an IgM test, which indicates an exacerbation of the infection. Only if IgM is elevated does it need treatment. The scheme you provided is not a treatment. Most likely, some other infection was detected in your regular smear: gardnerellosis, elevated white blood cells,? If not, you don’t have to take the prescribed medications; they won’t save you from chlamydia, and in general you don’t need treatment during your tests. Maybe there were some other tests with some other results?

The analysis revealed Cytomegalovirus and Ureaplasma. Treatment was prescribed - Isoprinosine (5 days. 2 t. * 3 times), Tinidazole (5 days. 1 t * 2 times), Macropen (6-10 days), Trichopolum (11-15 days. 1 t * 3 times). I haven’t seen the first two medications in any article (and they are expensive). Is their use justified? I am not pregnant and have not given birth.

Isoprinosine is a drug that stimulates the immune system, i.e. does not act directly on the infection, but helps the body cope with it. From my point of view, it is not a necessary component of therapy. In addition, the effect of immune drugs on the immune system is not fully known. Tinidazole is an analogue of Trichopolum, so it is completely replaceable. The only point: it is so widely used in practice that many bacteria are no longer sensitive to it.

After a miscarriage at 6 weeks, I was diagnosed with ureaplasma +++ and mycoplasma ++, although there are no signs of the disease. She underwent a course of antibiotic treatment, but as a result, the infection did not go away, but psoriasis began to grow throughout the body, although before it was almost invisible. Now I'm afraid to be treated with antibiotics, because... It is more difficult to cure psoriasis. Can I have a baby now?

These microorganisms in 30% of men and women are representatives of the normal microflora of the genital tract. Most often they occur in sexually active people. If they do not cause inflammation in either you or your partners, then no treatment is required. If there is no inflammation, then there is no threat to pregnancy. If inflammation is present, appropriate therapy is carried out. After a miscarriage, you should abstain from pregnancy for 6 months. The cause of miscarriage is not only infection, but also hormonal disorders.

When I came to register at the hospital at 12 weeks of pregnancy, the doctor said that I had cervical erosion. After the birth, the doctor did a biopsy and said that it was not erosion and directed me to take a smear for ureaplasma, mycoplasma, chlamydia, herpes virus and blood from a vein for toxoplasmosis and cytoplasmovirus. I've passed. Then it turned out that instead of a smear for ureaplasma, they took a smear for Trichomonas vaginalis. But the doctor said that if there is no Trichomonas vaginali, then most likely there will be no ureaplasma. And she said you don’t have to test for toxoplasmosis at all, since it most likely won’t happen (since I didn’t have a miscarriage during this pregnancy, everything is fine with the child and nothing bad happened to him at all). As a result, chlamydia, mycoplasma, herpes virus, Trichomonas vaginalis and toxoplasma were not found. But I have something on the cervix (it looks like erosion, but not erosion). The doctor believes that this is due to hormonal disorders during pregnancy.
QUESTIONS:
1. What could be wrong with me?
2. Is it true that since there is no Trichomonas vaginalis, then there are no ureaplasmas?
3. Is it true that there should be no toxoplasma, since the child is healthy and was born normal?
4. Could this be caused by Staphylococcus aureus in me (it was discovered in the child after birth, but it is not in the milk) and how can I determine if I have it (they took a simple smear from me after giving birth, they discovered colpitis, I have already cured it): Would they have found it with a regular smear if it was there, or do we need to do a special test for staphylococcus?

1. What is and what is the essence of treatment. With cervical erosion, the columnar epithelium (mucous membrane) of the inner part of the cervical canal is located on its vaginal part, where the squamous epithelium (mucous membrane of the outer part of the cervix) should be. The reason may be the youthful structure of the cervix. In women over 24 years of age, this structure is considered pathological. The cause of erosion in adulthood is most often the inflammatory process in the cervix, and in second place - hormonal disorders. When it is cured, erosion, if it is small, can heal itself. During childbirth, tears and tears form in the cervix, as a result of which the cervix seems to turn out a little. In this case, the mucous membrane of the cervical canal is everted into the vagina. This is no longer called erosion, but ectropion. The cervix becomes loose and easily vulnerable. At the same time, various pathological processes can develop in it. The risk of developing pathology is higher with a large size of erosion. If the erosion is large or has pathological changes, treatment is necessary. Erosion therapy consists of destroying the pathological epithelium, then forming a normal one in its place. For women who have not given birth or who have given birth, but with very slight erosion, they do not cauterize it, unless it turns into leukoplakia, dysplasia, etc. It is recommended to see a gynecologist once every 6 months. If treatment is still necessary. Erosion is cauterized using a laser; cryodestruction (freezing) and diathermocoagulation are also used. The latter is less preferable due to side effects. In addition, upon examination, inflammation of the cervix can be mistaken for erosion -. If the biopsy does not reveal pathological changes, the most common of which are dysplasia and leukoplakia. Then you can simply be observed once every 6 months. see the doctor, there is nothing wrong with you. Otherwise it is necessary to be treated.
2. 30% of men and women are representatives of the normal microflora of the genital tract. Most often they occur in sexually active people. If they do not cause inflammation in partners, then no treatment is required. If inflammation is present, appropriate therapy is carried out. is a sexually transmitted infection. So the absence of one does not absolutely exclude the presence of the other.
3. If you have pets, especially cats, that walk along the street, then there is a possibility that you have one. But since the child was born healthy, and the pregnancy proceeded without complications, then the disease is either in a dormant form or it really does not exist.
4. In order to find out whether you have Staphylococcus aureus, you need to do a culture. Secretions are taken from the genital tract and placed on a nutrient medium. Within a week, microorganisms living in the vagina germinate, and then determine what kind of bacteria they are and which antibiotics they are sensitive to. But keep in mind that small amounts of Staphylococcus aureus can be found in the genital tract normally.

Please answer my three questions, since I can’t find answers to them:
1. Can I get a sexually transmitted infection again if my husband and I have recently been cured of ureaplasma, but there are no other infections? (And how).
2. Does a decrease in prolactin levels (I’ve been taking parlodel for only 2 months) indicate that the pituitary adenoma is shrinking, or is this only for the time being to treat symptoms (in fact, NMR has not revealed convincing evidence for prolactinoma), and does such a rapid decrease in prolactin indicate that there really is no tumor? (I plan to have a child in the near future, could this really affect my health in connection with such an analysis).
3. Can the color fields of vision be narrowed on their own if no pituitary adenoma is detected? (The ophthalmologist confirmed the narrowing of the color fields, but the peripheral ones are normal

1. If you and your husband have cured everything, used contraception during treatment, and you have no other sexual partners, then there should not be a new infection. What could happen: an old untreated infection may worsen, dysbiosis () may develop, which you mistakenly consider an infection, may develop against the background of reduced immunity.
2. Parlodel is a special medicine that blocks prolactin synthesis. Naturally, while taking it, the level of this hormone decreases. Pituitary adenoma, if present, decreases only with long-term use. Another important indicator is the disappearance of the symptoms of hyperprolactinemia: milk discharge from the mammary glands, headaches. if they were... If there is an adenoma, planning a pregnancy until it is completely cured is undesirable, since all tumors grow and progress during pregnancy. Still, the most accurate way to diagnose a tumor is NMR, and it is its data that you should focus on. But if the symptoms have completely disappeared, Parlodel can be discontinued and prolactin levels monitored. Taking Parlodel will not affect pregnancy, but it is better to stop taking it before you plan to conceive.
3. Narrowing of color fields of vision is a specific sign of pituitary adenoma. They simply cannot be narrowed down. If there is no adenoma, then there is some other pathology of the pituitary gland.

I am 24 years old, tests showed that I have ureaplasma and condylomatosis. Please tell me what treatment you could recommend for me and how quickly I need to get rid of this kind of thing?

These infections are normal in 30% of women. They are most often found in sexually active women. If they do not cause inflammation in either you or your partner, then no treatment is required. Condylomatosis is a disease caused by. A manifestation of this disease is condylomatous growths. Condylomas are contagious and must be treated. Therapy is prescribed by a doctor.

what test is best to do after a course of treatment for ureaplasmosis (culture, ELISA or PCR). 2 months have passed since the course of treatment. I will not give a treatment regimen, but will simply list all the drugs. She was treated with Rulid, Macropen, Doxycycline, Cycloveron (injections), KIP suppositories, nystatin, Viferon-suppositories. I don’t know what to think, but it seems to me that this disease has become chronic, because... the symptoms of this disease (burning sensation, pain when urinating, etc.) returned a month after stopping treatment.

In 10% of women, they are representatives of the normal vaginal flora. They are most often found in sexually active women. Treatment is carried out if they do not cause an inflammatory process in you and your partner. Therefore, you need to take a regular smear for flora. Based on the results of this analysis, one can judge the presence of an inflammatory process. The same analysis will show the presence of a fungal infection or bacterial vaginosis, diseases that are the result of long-term and massive antibacterial therapy, and may also be the cause of the symptoms you experience. The cause of pain when urinating may be cystitis or urethritis, which are caused not only by ureaplasma, but also by such banal flora as E. coli. Contact a urologist, a specialist who deals with problems of the genitourinary system. Take a urine test and urine culture for flora and determine its sensitivity to antibiotics.

A year ago I was diagnosed with ureaplasmosis. After treatment with antibiotics (in my opinion, sumamed), ureaplasma was not detected during repeated analysis. My husband didn’t take any tests, but we were treated together. Now (a year later) the infection has been detected again (neither my husband nor I had contact with other partners). Please tell me what could be causing the relapse, and whether a complete cure is possible in principle or, once it appears, this infection will constantly make itself felt. Is it possible to cure it without the use of antibiotics, by, for example, increasing immunity?

Re-detection of the infection is possible if your spouse has not been completely cured. This infection is a normal variant in 10% of women. Most often it occurs in sexually active women. If these microorganisms do not cause inflammation in either you or your partner, then no treatment is required. If inflammation is present, treatment is necessary. Unfortunately, immunostimulating drugs play only a supporting role in the treatment of these diseases.

Ureaplasmosis 1:20. How serious is it? Can infection cause the body's inability to conceive? (7 months )

It all depends on the titer of which immunoglobulin you mean. If it is IgM, then this indicates a recent infection, if IgG, then you have been cured of this disease, the antibodies simply remain in the blood for some time. However, even if this is a recent infection and the bacterium is present in the body, but does not cause an inflammatory process (this can be determined by a regular smear on the flora), then there is nothing to worry about.

I am currently being treated for ureaplasmosis, can I start taking hormonal contraceptives or should I wait?

Antibacterial treatment is not a contraindication to taking (OK). Some antibacterial drugs reduce the effectiveness of hormonal contraceptives. If the treatment used does not affect the effect of contraceptives, then you may well start using them; otherwise, in addition to taking OK, you need to protect yourself with other methods (condom).

1. What may be the consequences after suffering from chlamydia and ureaplasma - how to check whether infertility has occurred or not.
2. I started having problems with my kidneys (cirrhosis, I think it’s called) - does this mean that this is a consequence of these diseases? What other problems might I encounter? How to understand How else did this infection manage to cause harm before it was cured?

Answer: and ureaplasmosis - sexually transmitted infections that cause inflammation in the genitals. Chlamydia causes a strong adhesive process in the pelvic and abdominal organs. The consequence of the adhesive process is infertility and pain in the lower abdomen. Inflammation of the appendages caused by chlamydia is difficult to treat and tends to recur. Chlamydia and ureaplasmosis can cause inflammation of the cervix and, as a result, formation.
You can check the patency of the fallopian tubes using kymographic pertubation (gas or air is passed through the uterus and fallopian tubes and contraction of the fallopian tubes is recorded) or hysterosalpingography (x-ray examination of the uterus and tubes). If obstruction is detected, surgical treatment is performed using laparoscopic techniques.

Lately I have often started to feel a burning sensation in my vagina. Some time ago, ureaplasmosis was discovered and she was treated. Tests showed that there were traces left; I tested it for biovar: nothing was found. Thrush pops up periodically. Could this be a consequence of it?

One of the symptoms of a fungal infection, which you apparently mean by, is itching and burning of the genital tract. Ureaplasmosis can also be a cause of vaginal inflammation. You need to be examined and, if these infections are detected, treated

A year ago I was diagnosed with urea and mycoplasma. She did not treat. Six months later, I installed a spiral. Now I have problems with discharge, I want to be cured. Is it necessary to remove the spiral and is it too late for treatment? At what stage of the disease does infertility occur?

The need to remove the IUD during treatment will be determined by your attending physician. The combination of intrauterine contraception and infections is a significant risk factor for the development of inflammation in the genital tract. The inflammatory process can provoke the formation of connective tissue - adhesions, and, as a result, infertility. The formation of adhesions may begin immediately after infection, or may not begin even after 10 years of inflammatory diseases - depending on your luck, treatment must begin immediately.

During the examination, my friend was found to have ureaplasma. I wanted to ask about this disease, as well as about its diagnosis and the possibility of doing it in Moscow. I would also like to know about treatment methods.

The correct name is ureaplasmosis. An infectious disease caused by ureaplasma - a microbe. Treated with antibiotics.

Although most experts consider PCR diagnostics to be the most reliable in detecting ureaplasmosis, not all laboratories carry it out, so sometimes patients have to take ELISA or RIF. The results of these tests sometimes raise doubts about the presence of the causative agent of ureaplasmosis in the body, especially in the early stages of the disease or during the recovery period, when a course of treatment has been completed. In such cases, a false positive result of ureaplasma may be obtained. With such a conclusion, a comprehensive examination is required in order to confirm or reject this conclusion and state complete recovery.

A false positive result with ELISA can be obtained after treatment. There are still antibodies in the blood, which will definitely reveal themselves for a long time when examining the material, showing a positive reaction. At the same time, PCR and bacterial culture do not detect the viruses themselves and give a negative answer. Doctors call this phenomenon a “residual trace” after a course of therapy. To make sure that the virus is really absent, you can do the ELISA again after a few months and compare the titers. With a false positive result, ureaplasma is absent, so titers will decrease over time.

The result of ureaplasma may be false positive due to the fact that when carrying out the ELISA and PCR methods, completely different material is taken for research. If the ELISA shows class A antibodies, then there is an infection in the body and the fight against it is already underway, as evidenced by the presence of immunoglobulins in the blood. However, a PCR test can indicate a negative result on the same day. This happens solely because the material was taken from the wrong place where viruses live. Since antibodies are found in the blood, they can be found anywhere. With the causative agent of the disease, everything happens completely differently. Ureaplasma in the body can be local, that is, in a certain area. If it is present in the uterine cavity, then when examining urethral discharge, the analysis will be negative. This happened only because the area for collecting material was incorrectly defined.

There is ureaplasma in the body, which has been shown to be effective by PCR, but there are completely no antibodies in the blood if the immune system is weakened. This situation is also a reason to draw a conclusion about a false positive result, because the PCR and ELISA readings do not match. In this case, you can start

In humans, only two species of this genus are capable of causing the development of a pathological process: ureaplasma urealiticum and. The habitat of these microbes is the genitourinary area. In more rare cases, the microorganism is found in lung and kidney tissue.

Ureaplasma urealyticum and ureaplasma parvum cause. This disease is more often diagnosed in women, since men usually do not have acute symptoms. Ureaplasmosis is a sexually transmitted sexually transmitted disease. In women, one pathogen is more often detected, and in rare cases, two pathogens are detected at once, which allows us to draw a conclusion about the presence of ureaplasma spp. Ureaplasma parvum has more pronounced pathogenic properties than ureaplasma urealyticum. Treatment of infection caused by ureaplasma parvum is more complex and lengthy, and the risk of complications is very high.

Ureaplasma infection is currently widespread. Experts note a high degree of colonization of the genitourinary organs with ureaplasma urealiticum: in men - 25%, in women - up to 60%.

Ureaplasma urealyticum

Ureaplasma urealyticum gets its name from its ability to break down urea. This is its main difference from those included in the same genus. The ability to realize is a trigger for the development of urate nephrolithiasis and urolithiasis.

U.urealyticum is a causative agent of sexually transmitted infections. The disease is characterized by signs of prolonged inflammation with complications and sexual transmission of the pathogen. Ureaplasma urealyticum can cause asymptomatic carriage and realize its pathogenic properties only under certain conditions.

Factors that provoke inflammation of the urogenital tract:

  • Diseases of the genital organs,
  • Decreased immune defense
  • Sexual infections
  • Inflammation of the prostate
  • Immunodeficiencies and impairment of local defense factors,
  • Vaginal dysbiosis in women.

Ureaplasma urealyticum is a T-mycoplasma capable of forming small colonies. Microbes grow at a temperature of 37 °C and an optimal pH of 6.5-7.0. Ureaplasmas are catalase-negative, inert to sugars, and cause beta-hemolysis of rabbit and guinea pig erythrocytes. A feature of ureaplasma is the need for urea and cholesterol. They break down uric acid to ammonia, grow well on dense enriched media and practically do not grow on liquid media.

According to generally accepted medical standards in women, ureaplasma urealyticum is an opportunistic microorganism that exhibits its pathogenic properties only under the influence of unfavorable factors. In association with other pathogenic or opportunistic microbes, ureaplasma can lead to the development of a number of pathologies that require urgent treatment. In most cases, this microorganism is highly resistant to modern antibiotics and is difficult to treat.

Routes of transmission

The spread of ureaplasma infection occurs as follows:

  1. Ureaplasma urealyticum is a causative agent of sexually transmitted infections. Infection occurs during unprotected sexual intercourse with an infected person. The microorganism feels great on the surface of sperm and on the vaginal epithelium.
  2. By ascending route, microbes penetrate the genitourinary system and the uterus. The vertical route of transmission of infection occurs when ureaplasma penetrates from the vagina and cervical canal into the ureter and kidneys.
  3. Transmission of infection from mother to fetus occurs through the transplacental route. Intrauterine infection is possible through the gastrointestinal tract, skin, eyes and organs of the urinary system of the fetus.
  4. During childbirth, mechanical infection of the newborn occurs during passage through the birth canal.
  5. Organ transplant patients can become infected. This is a transplantation route for the spread of infection.
  6. In more rare cases - anal and oral contact.
  7. The contact-household method accounts for less than 1%.

What causes ureaplasma urealyticum?

Among women

The microbe can cause the development of pelvic diseases, bacterial diseases, cervical erosion, cervical insufficiency, and infertility in women.

Ureaplasma infection in women often occurs latently. The pathology clinic is determined by the location of the pathological process. Women experience moderate mucous discharge, pain and burning sensation when urinating, aching and cramping pain in the abdomen, itching of the genitals. Symptoms are usually mild and disappear quickly. The infection is activated by nervous overstrain, physical fatigue, and weakening of the body's defenses.

An infected woman does not feel any effects of the microbe on her body. She usually leads an active sex life, does not use protection, and plans to have a child. Complications in women develop extremely rarely. In weakened individuals with reduced general resistance, the diseases described above arise that require antibiotic therapy.

In men

In men, ureaplasma urealiticum provokes the development of cystitis and sexual dysfunction. The first symptoms appear a month after infection. Ureaplasma infection in men disrupts spermatogenesis and promotes kidney stone formation. With urethritis, the head of the penis turns red, there is itching and burning in the urethra, pain that increases with urination, and clear discharge. In advanced cases, the infection can spread to the prostate and kidneys.

Chronic ureaplasmosis in men occurs without subjective symptoms. In the mornings or after a long period of urinary retention, scanty, cloudy discharge appears. The external opening of the urethra often sticks together, the urine becomes cloudy, and a “urine” smell appears. In men, carriage is practically not observed.

Diagnostic methods

To determine the etiological significance of ureaplasma urealyticum in the development of the disease, it is necessary to establish the number of microbial cells in the discharge of the genitourinary organs.

  • Typically, people who are preparing to become parents and are under the supervision of specialists at a family planning center are sent for analysis.
  • Pregnant women are screened for this infection.
  • Persons with chronic pathology of the genital organs must undergo an examination to determine the etiology of the pathological process.
  • All persons suspected of having sexually transmitted diseases should be examined.

The main diagnostic methods for ureaplasma infection are:


Treatment

If there are corresponding symptoms and when the pathogen is isolated in an amount of more than 10 4 CFU/ml, the disease must be treated. Antibacterial therapy is indicated for patients.

During treatment, patients must abstain from sexual activity, do not drink alcohol, do not sunbathe in the sun or in a solarium, and do not drink milk, carbonated and mineral water. The duration of treatment is 10-14 days. Both sexual partners should be treated.

In the absence of timely and adequate treatment, ureaplasmosis can lead to the development of serious complications: prostatitis, salpingo-oophoritis, pyelonephritis. The cause of infertility in men is a violation of the process of sperm formation. Ureaplasma urealyticum causes impaired sperm motility and quantity, and the appearance of pathologically altered forms. In women, infertility is caused by infection of the endometrium with ureaplasma or infection of the fertilized egg.

Prevention of ureaplasmosis

Preventive measures to prevent the development of ureaplasmosis and other sexually transmitted diseases:

  1. Using condoms.
  2. Use of antiseptic solutions after sexual intercourse - Miramistin, Chlorhexidine, suppositories - Polizhenax, Hexicon.
  3. Strengthening the immune system.
  4. Genital hygiene.
  5. Periodic screening for STIs.

Ureaplasma urealyticum is the causative agent of a typical venereal disease that requires treatment to avoid complications and the spread of sexually transmitted infections in society.

Video: specialist about ureaplasma

Video: obstetrician-gynecologist about ureaplasma



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