Antihistamines during pregnancy. What antihistamines can be taken during pregnancy - allergy remedies. The safest antiallergic drugs for pregnant women

Allergy is represented by an atypical immune response to any irritant that has entered the body. Sometimes familiar, non-hazardous substances can provoke a painful reaction in the body. Allergies can show up in various bodies, body systems. Faced with such a problem, future mothers consult with specialists. They are interested in the question: which antihistamines during pregnancy are less dangerous for their baby.

Varieties of allergies in pregnant women

To easily recognize the signs of an atypical reaction of the body to allergens in such a delicate position in women, you need to know what types of allergies are:

  • . This type of reaction is considered the most common in pregnant women. It is observed not seasonally, but at any time of the year. Most often manifested from the second trimester;
  • Conjunctivitis. It occurs when a certain allergen enters the eye. It rarely occurs on its own. It usually accompanies rhinitis;
  • Dermatitis, urticaria. Skin reaction manifested by redness, rash on the dermis, itching, peeling of the epithelium;
  • . This pathology is fixed in 2% of pregnant women. Its exacerbation is observed at the end of the 2nd trimester;
  • Quincke's edema;
  • Anaphylactic shock.

Any kind of allergic reaction should be treated under the supervision of a specialist.. This condition of the mother is dangerous due to hypoxia (oxygen starvation) of the fetus. The development of fetal hypoxia is provoked by spasms of the vessels of the placenta, which occur when certain drugs are taken, swelling of the nasal mucosa, lung tissues, and respiratory failure. Having diagnosed an allergy in a pregnant woman, the doctor prescribes certain antihistamines for pregnant women.

Causes of an allergic reaction

During the bearing of a child, there is an increased production of cortisol by the body, which exhibits anti-allergic activity. Given this feature, pregnant women rarely suffer from signs of allergies. But there are exceptions. It is more difficult for pregnant women to get sick, because many medicines are contraindicated for them because of their special situation.

How do antihistamines work?

Pharmacists have developed three generations of antihistamines. They have the same principle of action, the difference is represented by the accuracy, selectivity of the attachment of drug molecules to the receptor sites of the body.

Histamine is responsible for the occurrence of immediate allergy symptoms. This organic compound produce special mast cells, then it attaches to 3 types of receptors. These receptors are located in different places:

  • stomach;
  • nervous system;
  • most body tissues.

Under the influence of antihistamines, free receptors are engaged, blocked for a certain period. At the same time, there is a decrease in the severity of the allergic reaction.

Effective antihistamines during pregnancy

Pharmacists have created antihistamines for several generations. Medicines improve over time. This manifests itself in the following points:

  • decreased addiction;
  • reducing the strength of side effects;
  • decrease in quantity side effects;
  • increase the duration of the drug.

First generation agents can be used in the treatment of acute allergic conditions in pregnant women (the annotation states that they are prohibited when carrying a baby). The most common are:

  • "", "Chloropyramine". They are used in the 2nd, 3rd trimesters (provided that the benefit to the mother significantly outweighs the potential risk to the fetus);
  • "Tavegil", "Clemastin". Reception by pregnant women is allowed only for health reasons (if it is impossible to use another medication). In a number of cases, a negative effect on the offspring was noted when conducting a study on pregnant rats. Defects of extremities, heart defects were recorded in the offspring;
  • "Dimedrol". Assign only in extreme cases because of the ability to cause hyperexcitability uterus;
  • "Pipolfen", "Promethazine". These medicines are not prescribed during pregnancy.

Second-generation antihistamines include the following:

  • "Astemizol". Due to the toxic effect on the fetus, its use when carrying a baby is prohibited;
  • "", "Claritin". Pregnant women are prescribed after an adequate assessment of such risk / benefit indicators;
  • "Azelastine". According to the tests, the dose exceeding the therapeutic dose does not have a teratogenic effect on the fetus. But in the 1st trimester, it is not recommended for pregnant women to take it.

The third generation includes such drugs:

  • "Fexofenadine", "Telfast". Against allergies in pregnant women is used only as directed by a specialist;
  • "Zirtek", "Parlazin", "Cetirizine". Pregnancy for the use of these drugs is not considered an absolute contraindication. According to animal studies, these drugs do not have a teratogenic, mutagenic, carcinogenic effect on offspring;
  • Desloratadine, Levocetirizine. Medicines do not have a cardiotoxic effect.

What antihistamines can be taken in different periods pregnancy, see below.

1 trimester

Is the period when everything antihistamines strictly contraindicated.

2 trimester

This period of pregnancy does not have such severe restrictions as the first. Experts focus on the fact that not a single antihistamine agent guarantees absolute safety for an unborn child.

During this period of gestation, doctors may prescribe such drugs:

  • "Suprastin";
  • "Zyrtec";
  • "Desloratadine";

3rd trimester

Usually characterized by a decrease in the manifestation of allergic reactions. Pregnant women experience significant relief. Doctors may prescribe antihistamines, taking into account the possible risks to the fetus, the benefits to the mother. Used against allergies:

  • "Zyrtec";
  • "Desloratadine";
  • "Claritin";
  • "Azelastine".

How to alleviate (eliminate) the manifestation of allergies during pregnancy?

Specialists warn expectant mothers that there is no antihistamine drug that is completely safe to use. For removal allergic symptoms they suggest trying natural antihistamines (certain vitamins). These substances will help to cope with unpleasant symptoms without harming the fetus.

Of the vitamins, the following have an antiallergic effect:

  • AT 12. It belongs to the universal natural antihistamines. Used in the treatment of dermatitis, allergic asthma. The doctor may prescribe a course of treatment for 3 to 4 weeks. It is worth taking 500 mg of vitamin per day;
  • WITH ( ascorbic acid). Respiratory allergy symptoms can be minimized by taking 1 to 4 grams of acid per day. This vitamin prevents an anaphylactic reaction;
  • pantothenic acid. It is prescribed for allergic rhinitis. 100 mg of the drug can alleviate the symptoms of the disease. It should be taken before bed. Over time, the dosage can be increased (250 mg);
  • Zinc. Assign to reduce allergies to household chemicals, perfumes, cosmetics. It is recommended to take in a complex compound (aspartate, picolinate). A pure trace element can cause anemia. The therapeutic course is about a month. Daily dose 50 - 60 mg;
  • A nicotinic acid. Reduces the severity of allergy symptoms. It is shown at reaction of an organism to pollen of plants. The therapeutic course is about a month. Daily dose 50 - 60 mg;
  • Linoleic acid, fish fat. They help prevent the development of allergic reactions (itching, runny nose, redness of the eyes, lacrimation, redness of the dermis);
  • It is used to prevent allergic reactions.

Such antihistamines during pregnancy will bring more benefits to the mother, and the fetus will not be harmed. Taking vitamins is allowed only after consulting a doctor. Dosage, course of therapy is prescribed by a specialist.

Allergy medications prohibited during pregnancy

When carrying a baby, a future mother needs to think first of all about his health. Symptoms of an allergic reaction are simply unbearable, but taking medication without consulting a specialist is strictly prohibited. There are a number of drugs that are prohibited during pregnancy. This list is quite large:

  • "Betadrine". The use of this medicine is prohibited at all stages of pregnancy;
  • "Dimedrol". The drug is able to affect the contractile function of the uterus. It cannot be used throughout pregnancy;
  • "Tavegil". Taking this medication can cause birth defects in the fetus. It is prohibited during the gestation period;
  • "Claritin". When carrying a fetus, the doctor may prescribe this medication only for health reasons;
  • "Pipolfen". The entire period of gestation is forbidden to take this drug;
  • "Astemizol". Able to have a teratogenic effect (in other words, causes malformations). It is not prescribed for pregnant women;
  • "Ketotifen". Its use in pregnant women is contraindicated due to the lack of data regarding its effect on the fetus;
  • Cromolyn sodium;
  • "Zafirlukast";
  • "Histaglobulin".

The use of antihistamines can be dangerous for the unborn baby. Pregnant women should not risk self-medication. An antiallergic medication should be prescribed by a specialist after examining the patient, determining the allergen.

There are several reasons for this. Among them are the hormonal restructuring of the body, and the reaction to the tissues and waste products of the fetus, and the seasonal factor also joins.

Fearing harmful effects on the fetus, women try to avoid taking extra pills. But at the same time, they experience discomfort from allergies: shortness of breath or itching interfere with proper rest and relaxation. What pills can be taken during pregnancy?

Allergies are faced by a huge number of people. Men and women of all ages are affected allergic reactions children are highly susceptible. Therefore, research in this area and the development of new drugs is very active.

Allergy medications that require multiple doses and cause drowsiness are being replaced by new generation formulas - with prolonged action and a minimum of side effects.

Vitamin preparations for allergies

Do not forget that not only antihistamines can help, but also some vitamins. And pregnant women usually have a more trusting attitude towards them.

  • vitamin C can effectively prevent anaphylactic reactions and reduce the incidence of respiratory allergies;
  • vitamin B12 is recognized as a powerful natural antihistamine, helps in the treatment of dermatosis and asthma;
  • pantothenic acid(vit. B5) will help in the fight against seasonal allergic rhinitis and reaction to household dust;
  • nicotinamide (Vit. PP) relieves seizures spring allergies on plant pollen.

Traditional antihistamines: allergy pills

Newly emerging drugs are effective and do not cause drowsiness. However, many doctors are trying to prescribe more traditional remedies for pregnant women.

For drugs that have been on the market for 15-20 or more years, enough statistical data has been collected to talk about their safety or negative impact on the health of the fetus.

Suprastin

The drug has been known for a long time, it is effective in various manifestations allergies, is allowed for both adults and children, and therefore is also allowed for use during pregnancy.

In the first trimester, when the fetal organs are forming, this and other drugs should be taken with extreme caution, only in case of emergency. In the rest of the period, suprastin is allowed.

Advantages of the drug:

Flaws:

  • causes drowsiness (for this reason, it is prescribed with caution in the last weeks before childbirth);
  • causes dry mouth (and sometimes mucous eyes).

Diazolin

This drug does not have such speed as suprastin, but effectively relieves the manifestation of chronic allergic reactions.

It does not cause drowsiness, therefore, there are restrictions in the appointment only in the first 2 months of pregnancy, in the rest of the period the medicine is approved for use.

Advantages of the drug:

Flaws:

  • short-term effect (requires taking 3 times a day).

cetirizine

Refers to the new generation of drugs. It can be produced under different names: Cetirizine, Zodak, Allertec, Zyrtec, etc. According to the instructions, cetirizine is prohibited for use during pregnancy and lactation.

Due to the novelty of the drug, there is not enough data on its safety. But, nevertheless, it is prescribed to pregnant women in the 2nd and 3rd trimester in situations where the benefits of taking it significantly outweigh the risk of side effects.

Advantages of the drug:

  • a wide range of activities;
  • speed;
  • does not cause drowsiness (except for individual reactions);
  • reception 1 time per day

Flaws:

  • price (depending on the manufacturer);

Claritin

The active substance is loratadine. The drug can be produced under different names: Loratadin, Claritin, Clarotadin, Lomilan, Lotharen, etc.

The same as that of cetirizine, the effect of loratadine on the fetus has not yet been sufficiently studied due to the novelty of the drug.

But studies conducted in America on animals have shown that the use of loratadine or cetirizine does not increase the number of pathologies in the development of the fetus.

Advantages of the drug:

  • a wide range of activities;
  • speed;
  • does not cause drowsiness;
  • reception 1 time per day;
  • affordable price.

Flaws:

  • used with caution during pregnancy.

Feksadin

Refers to the new generation of drugs. It is produced in various countries under a different name: Feksadin, Telfast, Fexofast, Allegra, Telfadin. You can also meet Russian analogue- Gifast.

In studies on pregnant animals, fexadine showed the presence of side effects when long-term use V large doses(increased mortality due to low fetal weight).

However, no such dependence was found when administered to pregnant women.

During pregnancy, the drug is prescribed for a limited period and only in case of ineffectiveness of other medicines.

Advantages of the drug:

  • wide spectrum of action
  • performance
  • reception 1 time per day.

Flaws:

  • with caution is prescribed during pregnancy;
  • effectiveness decreases with prolonged use.

The drug in the form of capsules is currently not available on the Russian market. In pharmacies there are drops for oral administration and gels for external use.

The drug is approved for use in children infancy, and therefore often prescribed for pregnant women.

Gel for local treatment can be used without fear, it is practically not absorbed, does not enter the bloodstream. Fenistil is a part of antiherpetic emulsions.

Advantages of the drug:

  • safe even for babies;
  • average price range.

Flaws:

  • not a very wide spectrum of action;
  • limited release forms;
  • side reactions are possible.

These drugs differ in price and form of release (tablets for daily intake, injectables For emergencies, gels and ointments for local application, drops and syrups for children)

Name of the drug Release form, dosage Volume/quantity price, rub.
Suprastin Tablets 25 mg 20 pcs 150
Injection 5 ampoules of 1 ml 150
Diazolin Dragee 50/100 mg 10 pieces 40/90
cetirizine Cetirizine Hexal tab. 10 mg 10 pieces 70
Cetirizine Hexal drops 20 ml 250
Zyrtec tab. 10 mg 7 pcs 220
Zyrtec drops 10 ml 330
Zodak tab. 10 mg 30 pcs 260
Zodak drops 20 ml 210
Claritin Loratadine tab. 10 mg 10 pieces 110
Claritin tab. 10 mg 10 pcs/30 pcs 220/570
Claritin syrup 60ml/120ml 250/350
Clarotadine tab. 10 mg 10pcs/30pcs 120/330
Clarotadine syrup 100 ml 140
Feksadin Feksadin tab. 120 mg 10 pieces 230
Feksadin tab. 180 mg 10 pieces 350
Telfast tab. 120 mg 10 pieces 445
Telfast tab. 180 mg 10 pieces 630
Fexofast tab. 180 mg 10 pieces 250
Allegra tab. 120 mg 10 pieces 520
Allegra tab. 180 mg 10 pieces 950
Drops 20 ml 350
Gel (external) 30g/50g 350/450
Emulsion (external) 8 ml 360

Antihistamines with fetal side effects

Previously used antihistamines had a significant sedation, some also have a muscle relaxant effect. In some cases, it was useful in the treatment of allergies and even, but the effect on the fetus can be extremely negative.

Antihistamines are not prescribed before childbirth to keep the newborn active.

It will be difficult for a lethargic and “sleepy” child to take his first breath, this threatens with aspiration, possible pneumonia in the future.

The intrauterine effect of these drugs can manifest as fetal malnutrition, which will also affect the activity of the newborn baby.

  • Diphenhydramine

can cause premature contractions

  • Tavegil

has a negative effect on fetal development

  • Pipolfen
  • Astemizol (Histalong)

affects liver function, heart rate, toxic effect on the fetus

In order to avoid harmful effects on the fetus, antihistamines are not recommended for pregnant women during the first trimester. During this crucial period, when all the organs of the unborn child are being formed, the placenta has not yet been formed, and substances entering the mother's blood can affect the health of the fetus.

Medicines during this period are used only in case of a threat to the life of the mother. In the second and third trimester, the risk is less, so the list of acceptable drugs can be expanded.

However, in any case, preference is given to local and symptomatic treatment, antihistamine tablets are prescribed in small doses and for a limited period.

The appearance of allergic reactions is possible at any stage of life, including during the period of bearing a child. If they are life-threatening or significantly worsen a woman's well-being, a doctor may prescribe antihistamines during pregnancy. Such a decision is made taking into account the potential benefit to the mother and the risk to the fetus.

There are a number of drugs with a teratogenic effect, that is, they cause malformations or abnormalities incompatible with life in the unborn child. The possibility of this effect is evaluated primarily in studies on laboratory animals. It should be remembered that on early dates most of the medicines intended for the treatment of various diseases. Therefore, in the 1st trimester of pregnancy, the list of allowed drugs is very poor, and antihistamines are not included in it.

Types of allergies in pregnant women

A hypersensitivity reaction in pregnancy may occur for the first time, which is associated with a change in work immune system in this period. If a woman used to have allergic diseases, then they can change in severity during childbearing.

The main types of allergic manifestations in pregnant women:

  • rhinitis is the most common variant, not necessarily seasonal, usually occurring from the 2nd trimester;
  • conjunctivitis, rarely found in isolated form, usually combined with rhinitis;
  • local (contact) itchy dermatitis or eczema;
  • urticaria, in severe cases Quincke's edema;
  • symptoms of bronchial asthma, the risk of exacerbation of which is higher at the end of the 2nd trimester of pregnancy;
  • anaphylactic shock.

Allergy in the mother can cause hypoxia in the fetus. The reasons for this are spasm of the vessels of the placenta when using certain drugs, respiratory failure with swelling of the nasal mucosa or lung tissue. Therefore, the doctor prescribes necessary treatment, including antihistamines during pregnancy.

Antihistamines

Currently, there are 3 generations of antihistamines. Their principle of action is the same, and the differences lie in the accuracy and selectivity of attaching drug molecules to receptor sites in the body.

Histamine is responsible for the onset of immediate allergy symptoms. He stands out from the special mast cells and attaches to special receptors of 3 types. They are located in different places and are indicated Latin letter H. H1 receptors are the most common, they are found in almost all tissues, H2 is in the stomach, and H3 is in the nervous system.

Antihistamines occupy free receptors and block them on certain time. As a result, few points of application remain for the released histamine, which leads to a decrease in the severity of allergic reactions. Increasing the selectivity of drug attachment minimizes side effects when it is used.

Main Representatives

There are different types of antihistamines chemical structure depending on the class (generation) of drugs.

1st generation antihistamines have a powerful and quick effect, low selectivity and additional anticholinergic action. This group includes Suprastin, Diphenhydramine, Pipolfen, Diazolin and Tavegil. The main side effect is sedation.

Representatives of the 2nd generation are Claritin, Astemizol, Fenistil. They do not have an inhibitory effect on the central nervous system, since they do not penetrate the blood-brain barrier and do not block H3 receptors. But the result of treatment can be expected only after a few weeks of regular use.

Modern 3rd generation drugs are also intended for long-term therapy. allergic diseases. They do not have a cardiotoxic effect, which is inherent in some representatives of the 2nd generation of antihistamines, and are well tolerated. The most commonly used are Cetirizine (Zirtek, Cetrin), Erius, Telfast.

During pregnancy, it may be necessary to quick relief an acute allergic reaction, and long-term treatment diseases. But given the side effects and the possibility of drugs affecting the fetus, it is important to use not only effective, but also fairly safe means. Therefore, not all antihistamines can be used by women in an "interesting" position.

How to treat allergies in pregnant women

Even permitted antihistamines should not be taken on their own initiative and uncontrolled. A mandatory consultation with an allergist is necessary, which will select the right treatment. Pregnant women with an acute severe reaction are hospitalized. They are prescribed intensive complex therapy for the speedy relief of a dangerous condition that has arisen.

When a hypersensitivity reaction occurs in the first trimester, antihistamines should not be taken. Indeed, at this stage, the risk of developing complications of pregnancy and the influence of drugs on the formation of organs in a child is very high. For example, Astemizol and Tavegil have an embryotoxic effect. Diphenhydramine and Betadrine can cause uterine contractions and lead to spontaneous abortion. At the same time, if the life of the mother is threatened or if the treatment of early toxicosis is ineffective, the doctor may decide to prescribe some drugs of the 1st generation.

In the 2nd and 3rd trimesters of pregnancy, antihistamines can be taken on the recommendation of an allergist if potential benefit from such treatment outweighs the potential risks. The most commonly used are Cetirizine, Loratadine (Claritin), Feksadin (Telfast). Suprastin is used to treat acute allergic reactions under the strict supervision of a physician.

Before childbirth, it is advisable to cancel antihistamines so as not to cause sedation in the newborn and not to suppress his work. respiratory center.

So, if necessary, it is possible to use some antihistamines during pregnancy, but only under the strict supervision of a doctor.

Antihistamines are very often used to treat allergic reactions and pathologies. It is very difficult to completely get rid of allergies, and its predisposition. With the help of antihistamines, you can only partially get rid of the symptoms, this disease cannot be completely cured. A pregnant woman should be especially careful about taking them, almost all of them are contraindicated, because they can negatively affect the fetus in utero.

What allergic reactions can occur in pregnant women?

1. Allergic rhinitis, with which it is difficult nasal breathing and stuffy nose, the nasal mucosa swells, the discharge is watery.

3. Urticaria.

How to take antihistamines during pregnancy?

Pregnant women often have an allergic reaction and it is very difficult to choose medicines that can help relieve allergy symptoms during pregnancy. Remember that during pregnancy, you need to be careful about the use of antihistamines, only after consulting and recommending a doctor. In the first trimester of pregnancy, it is forbidden to use drugs of this group. In the second trimester, only after resolution and very great need, antihistamines can be used. You also need to pay attention to the fact that this group drugs are not remedy, which is completely safe and can be used.

Can natural antihistamines be taken during pregnancy?

These drugs help relieve an allergic reaction. Natural antihistamines include vitamins, they do not harm the unborn child, but rather relieve allergic symptoms:

1. Ascorbic acid or vitamin C. You need to take it from 1 to 4 grams per day, in this way you can completely get rid of respiratory allergies. With the help of ascorbic acid, an anaphylactic reaction can be prevented. But remember, only after you consult a doctor, you can take vitamins. Ten days at 500 mg per day.

2. Vitamin B12 is a versatile natural antihistamine. It is taken in order to reduce dermatitis and with. The drug should be taken for three to four weeks at 500 mg.

3. Pantothenic acid is used to relieve symptoms, you need to take 100 mg, always at night. Then the dose is gradually increased, which can be taken once or twice a day.

4. Nicotinic acid helps to get rid of the complications of allergies. Most often it is used when there is an allergy to plant pollen. It should be taken up to 300 mg per day per month.

5. Zinc helps protect against allergies to cosmetics, perfumes and household chemicals. This trace element must be taken in combination with aspartate or picolinate. You can not take one, it is dangerous because it can cause anemia.

6. Oleic acid is the main constituent olive oil. Olive oil is a prophylactic against allergies.

7. Linoleic acid and help prevent reactions such as itching, runny nose, tearing and redness of the eyes.

Remember, in order to prevent an allergic reaction of the body, you need to know the allergen and not come into contact with it anymore. To do this, special tests are carried out, for which potential allergens are used - herbal extracts, pollen, animal skin, drugs, etc.

Are antihistamines safe during pregnancy?

1. Diphenhydramine should never be used during the entire pregnancy, because it can cause or premature birth. For the same reason, betadrine should not be used. This drug is prescribed if a pregnant woman is very ill.

2. Suprastin can be taken, but only starting from the second trimester of pregnancy as prescribed by a doctor.

3. Tavegil should not be taken in the first trimester of pregnancy. This drug is used very rarely, only if there is a threat to life, because it has already been confirmed that it negatively affects the fetus.

4. Bikarfen during pregnancy should never be taken.

5. Flonidan can be prescribed only in rare cases.

6. Safe drug is Zyrtec, but it is very important to follow the dosage when using it.

7. In the second trimester you can take Pheniramine.

8. The well-known antihistamine drug Ditek, which is produced in the form of an aerosol, is also very dangerous during pregnancy, until the causes are identified and how it negatively affects the fetus, but it is better to stop using it. sodium, histaglobulin, ketotifen. Remember that taking antihistamines is dangerous for the unborn baby, therefore it is so important not to self-medicate, it is best to consult a specialist who will advise you on the drug that suits you.

10. In the second and third trimester, you can use Allertec.

11. It is possible to use Feksadin only in cases where there is a risk to the fetus.

So, it is very important to control the intake of antihistamines during pregnancy, in no case should you self-medicate, because almost all antihistamines are dangerous for the fetus and negatively affect internal organs. It is best to pay attention to natural antihistamines. And you need to understand that all antihistamines only relieve symptoms, and do not treat. And they are only used in cases where there is a threat to life for both the mother and the unborn child. But every pregnant woman should understand that taking medications affects the baby. Therefore, if the allergy is tolerable, you do not need to immediately grab the medicine.

It is impossible to completely exclude the occurrence of an allergic reaction during pregnancy. If for an ordinary patient this is not a particular problem, then it is not so easy for pregnant women. The main catch is choosing the optimal drug for allergies during pregnancy, which will be effective and safe.

Predisposition to certain types of allergens can be determined before the conception of a child by contacting a specialist.

The effect of allergies on the fetus

As evidenced clinical researches, a direct allergic reaction in a pregnant woman does not have a particular detrimental effect on the fetus. The thing is that allergens, having contacted with specific immunoglobulins in the blood (antibodies), cannot pass through the placenta. However, allergies are different allergies. severe forms, such as anaphylactic shock or angioedema, will always affect not only the health of the mother, but also the fetus. At the same time, mild forms (allergic rhinitis or conjunctivitis) can indirectly affect the development and formation of the child. As a rule, an allergy in a mother affects the baby through:

  • Deterioration general condition pregnant.
  • Features of treatment, in particular, antiallergic drugs used during pregnancy.

Prohibited drugs

Not all antihistamines that can suppress an allergic reaction can be given to pregnant women. Some drugs are absolutely contraindicated regardless of the gestational age, while others may have significant limitations in use. Here are some specific examples:

  1. Diphenhydramine is able to increase the excitability and contractility of the uterus ahead of time.
  2. Terfenadine leads to a decrease in body weight of a newborn child.
  3. Astemizol has a very negative effect on the intrauterine formation of the fetus.
  4. Allertec and Fenkarol are contraindicated in the early stages of bearing a child.
  5. Tavegil is used only in extreme cases, when the patient's life is in danger.
  6. Pipolfen negatively affects the fetus.

Currently pharmaceutical market crowded various analogues Diphenhydramine, Terfenadine, Astemizol, Tavegil, Pipolfen and other antihistamines that are not recommended for use while carrying a baby. If the official instructions indicate that the medicine is contraindicated for pregnant women, then it means that it cannot be used under any circumstances.

Approved drugs

What can you drink for allergies during pregnancy? It should be noted right away that not a single antiallergic drug should be taken without the approval of the supervising physician. The appointment of antihistamines is considered appropriate if the expected therapeutic effect of taking the drugs significantly exceeds possible risk for the fetus. What pills for allergies during pregnancy can be prescribed:

  • Loratadine.
  • Cetirizine.
  • Suprastin.
  • Chlorpheniramine.
  • Benadryl.

Loratadine

The representative of the second generation of antihistamines is Loratadine. It helps to stop an allergic reaction, eliminate increased vascular permeability and tissue swelling, and cope with itching. Most allergic diseases and conditions (rhinitis, conjunctivitis, urticaria, dermatitis, angioedema, etc.) are an indication for the use of Loratadine. What are the possible side effects of taking it?

  • Headache.
  • Drowsiness.
  • Weakness.
  • Depressive state.
  • Increased irritability.
  • Various functional disorders of the digestive system.
  • Difficulty breathing through the nose or mouth (bronchospasm).
  • Problems with urination.
  • Disruptions in the menstrual cycle.
  • Jumps in blood pressure.
  • Palpitation.
  • Pain in the joints and muscles.

Targeted clinical studies in animals have not recorded the negative effects of an antihistamine at therapeutic doses on the fetus. For women who have severe problems with the functioning of the kidneys or liver, the dosage of the drug should be adjusted.

Loratadine is available in tablets and is sold at a price of 16–20 rubles per pack. Claritin, Lorahexal, Lomilan, Claridol, Clarisens, Clarotadin, Tyrlor are considered analogues of this drug.

Any anti-allergic drug taken during pregnancy without the approval of a specialist doctor can provoke extremely severe consequences for woman and fetus.

Suprastin

Suprastin belongs to the first generation antihistamines. 20-30 minutes after application, the therapeutic effect begins. pharmachologic effect the drug lasts for 3-5 hours. Almost all types of allergic diseases are considered an indication for the appointment of Suprastin. The decision on the possibility of using this antihistamine during pregnancy is made by a specialist doctor.

Extreme caution must be exercised when using Suprastin in patients suffering from glaucoma, impaired renal and / or liver function, cardiovascular pathology. If the drug is taken at night, it is possible to increase clinical manifestations disease such as reflux esophagitis. Side effects are almost identical, as with Loratodin.

In some cases on early stages treatment with antihistamine medicine provokes the appearance of drowsiness, fatigue, decreased concentration and dizziness. For the duration of therapy, it is better to refrain from driving a car and professional activities that require precise manipulations and high concentration attention.

In pharmacies, a package of Suprastin tablets can be purchased for about 120-140 rubles. Among analogues, Suprastinex, manufactured by the Hungarian pharmaceutical company Egis, and domestic Chloropyramine are the most popular.

cetirizine

The classic antiallergic drug that is allowed to be prescribed during pregnancy is cetirizine. One of its distinguishing features is that it easily penetrates and accumulates in the skin. Therefore, cetirizine is considered the drug of choice for therapy. allergic dermatitis and hives. This medicine is very effective in permanent or seasonal allergic conjunctivitis and rhinitis.

A number of studies demonstrate the absence of pathological effects on the fetus. The antihistamine drug does not lead to malformations or disruption of the formation of the child. Also not found negative effect on a woman's fertility. However, cetirizine may be excreted in mother's milk. I would like to remind you that both during pregnancy and during breastfeeding, antiallergic treatment is fully prescribed and monitored by a specialist doctor.

In some patients, taking this antihistamine medicine may be accompanied by the appearance of unwanted adverse reactions, which usually disappear after stopping the drug. We list the most common:

  • Headache.
  • Weakness.
  • Increased fatigue.
  • Dryness in the mouth.
  • Nausea.
  • Violation of the liver.

Depending on the manufacturer and the number of tablets in a package, the price of Cetirizine can range from 55 to 85 rubles. Drops of this drug will cost you 230-250 rubles.

Chlorpheniramine

Of the first generation antihistamines, which have a pronounced antiallergic effect, Chlorpheniramine can also be noted. Available in pharmacies under trade name Pyriton. It is successfully used for all types of allergic reactions of varying severity. The dosage and frequency of administration is determined by a specialist, taking into account the patient's condition and the nature of the pathological manifestations. Side effects are similar to any first generation antihistamines. In case of unwanted clinical symptoms Chlorpheniramine should be stopped immediately.

If you have a tendency to allergic reactions (for example, rhinitis or bronchial asthma), then you should discuss with your doctor in advance which medications will be effective against allergies during pregnancy.

Benadryl

Today, many patients prefer Benadryl, which is available in the form of tablets and syrup. This antihistamine has been clinically proven to have several properties at the same time:

  1. Antiallergic.
  2. Bronchodilator (expands the bronchi, suppresses cough).
  3. Sedative (calming effect on the central nervous system).
  4. Anticholinergic (suppression of the transmission of nerve impulses).

The maximum concentration of the drug in the blood is noted within half an hour after taking the drug. Duration therapeutic effect persists for 4-6 hours. You can buy this drug without a prescription. However, pregnant women can take it only after consulting a specialist doctor. It is not excluded the occurrence of adverse reactions typical of first-generation antihistamines, such as fatigue, lethargy, dizziness, loss of strength, jumps blood pressure, disorders digestive system, neurological disorders, etc.

If the medicine is ineffective for several days, it is recommended to stop treatment and consult a doctor who will adjust the treatment.

Medications for mild allergies

According to clinical statistics, most often a pregnant woman develops allergic rhinitis, conjunctivitis or dermatitis. What are the main drugs for mild allergies during pregnancy:

  • Tablets (Suprastin, Cetirizine, Loratadine, etc.).
  • Nose drops (Aqua Maris, Marimer, Pinosol, Salin).
  • Eye drops (Allergodil, Kromoheksal).
  • External means (Fenistil-gel, Diphenhydramine, Elidel).

A woman in position should not use an antiallergic drug without obtaining the consent of the attending physician. It is worth noting that during early pregnancy, most medicines for allergies are contraindicated.

Prevention

Special attention should be given to the prevention of allergies in pregnant women. What measures should be taken to avoid the development of allergic diseases:

  1. Stick to a hypoallergenic diet. However, recent Scientific research show that by eliminating allergenic foods to which you are not allergic, you can significantly more harm than good. For example, omega-3 fatty acid, which are rich in fish and shellfish, contribute to the normal formation of the fetal brain, or folic acid, contained in peanuts, helps prevent defects in the development of the neural tube (back bifida).
  2. Completely exclude foods that may cause an allergic reaction.
  3. It is highly recommended to avoid contact with potential allergens. This mainly concerns household cleaning products, new cosmetics, etc.
  4. Regularly clean the apartment.
  5. To give up smoking. It has been proven that children whose mothers constantly smoke have a significantly increased risk of developing allergic forms dermatitis and bronchial asthma.
  6. Do not self-medicate. Uncontrolled intake of various medicines may result not in improvement, but in serious consequences for both the woman and the child.

Before using an allergy medicine during pregnancy, always carefully read the instructions for the drug.

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Causes of allergies in pregnant women

Experts call many reasons for the occurrence of allergies - both unfavorable ecology and the presence of alien to the body synthetic substances, and hormonal changes in the body during pregnancy. But with all this, the paradox lies in the fact that it is simply impossible to predict the immune response of the female body to stimuli. Theoretically, everything looks logical. During pregnancy, the body increases the production of cortisol, a steroid hormone that increases stamina and has a powerful anti-allergic effect. Therefore, the severity of the reaction, even in allergic women, is noticeably reduced, especially starting from the second trimester of pregnancy, when a sufficient amount of the hormone accumulates in the blood. However, in practice, there are three options for the development of allergies during pregnancy:

  • exacerbation of allergic reactions, incl. the appearance of symptoms in women who did not suffer from allergies before;
  • maintaining allergic reactions at the same level, regardless of the timing and course of pregnancy:
  • improvement of a woman's condition during pregnancy.

All this once again confirms how imperfect knowledge is. modern man in this branch of medicine.

How dangerous is an allergy for a pregnant woman and an unborn child?

For the most part, allergy symptoms cause trouble for the expectant mother. They have little effect on the child - the fetus is reliably protected from substances that cause allergies in the mother by the placental barrier. The risk that a child will be allergic is 40% if the mother suffers from allergies, 20% if only the father suffers from it, and 70% if both parents have it.

However, it should be noted that with a long development pathological process allergies adversely affect the condition of the fetus. Instead of directing its forces to its development and growth, the mother's body is struggling with allergens. Therefore, the situation cannot be ignored in any case. And first of all, you should start with local funds- drops and sprays in the nose, ointments, creams, etc. The use of tablets and injectables is resorted to only in last resort.

Nose drops from allergic rhinitis during pregnancy

From the modern arsenal of tools used to alleviate the condition of a pregnant woman, there are 3 main groups of nasal drops and sprays:

  • drugs based on sea ​​salt or saline solutions - Aqua Maris, Aqua Spray, Marimer, No-salt, Salin. When treating the nasal mucosa with hypertonic saline, allergens in a physical way removed from the mucosal surface. The method is simple, safe and effective. An additional plus - a solution for washing the nasal cavity can be made independently;
  • preparations based on essential oils - Pinosol. However, taking into account the fact that essential oils are allergens, these drops should be used with caution. It is best to first check the body's reaction to them. To do this, drip yourself 1-2 drops of the drug on the bend of the elbow. If within 24 hours there is no redness and burning of the skin in the area of ​​application, drops can be used as directed;
  • homeopathic preparations - Delufen, Euphorbium compositum. These funds are absolutely safe for pregnant women. The only contraindication of manufacturers is an allergic reaction to the components, but the concentration of active substances is so meager that this probability is extremely low.

Important! Do not use in the treatment of allergic rhinitis vasoconstrictors! They impair the blood supply to the mucosa and, with prolonged use, lead to necrosis (cell death). As for sprays containing hormonal agents, for example, Nasonex, Nazofan, Flixonase, their use should be agreed with the attending physician.

Antiallergic ointments during pregnancy

The approach to using creams, ointments and other external agents is the same as when using nasal drops - hormonal preparations should only be used as a last resort. With dermatoses of pregnant women, doctors often prescribe ointments of the following groups:

  • for moisturizing and nourishing the skin - most often these are ointments containing dexpanthenol (Panthenol, Bepanten, Heppiderm). It is a provitamin involved in the synthesis process skin, and beneficially affecting it with various kinds of inflammation;
  • anti-inflammatory - Fenistil (possible from the II trimester), Psilo-balm, Elidel, Psoriaten. The first two drugs are actively used in pediatric practice(Fenistil - in children from 1 month), so they can be used during pregnancy.

If there is a need to appoint hormonal ointments you should definitely consult your doctor. The most popular options for pregnant women are chlorine-containing glucocorticosteroids, for example, mometasone (Elokom, Momederm drugs). A feature of this active substance is that it is practically not absorbed into the blood and does not have a systemic effect on the body. Also, with prolonged use, it has fewer side effects characteristic of steroid hormones.

allergy pills during pregnancy

To one of the safe and effective ways relief of allergy symptoms include vitamin therapy. In addition to traditional complex vitamin preparations for pregnant women, the doctor may additionally prescribe vitamins A, C, B vitamins (pantothenic acid, a nicotinic acid, cyanocobalamin).

Despite the absence clear understanding mechanisms for the formation of allergic reactions, it was found that the state of the body's immune system is 70% dependent on the state of the intestine, 20% on the liver and 10% on other factors. That's why good effect gives the appointment of drugs that help normalize the work of these organs - hepatoprotectors (Antral, Glutargin, Liv-52, Karsil, Essentiale) and bacterial agents to correct the condition intestinal microflora(Simbiter, Fluvir, Bifi-form, Laktofiltrum, Prema Duo).

As for the classic drugs for the treatment of allergies, the so-called. antihistamines, there is none that can be called absolutely safe during pregnancy. Therefore, they should be appointed only in case of ineffectiveness of local and non-specific means and only on doctor's orders. Only a doctor, after weighing the benefits and risks for the mother and unborn child, will be able to choose best option treatment. Within the framework of this article, we note only that during pregnancy the use of the following means is prohibited:

  • Diphenhydramine - increases the tone of the uterus, can provoke premature birth;
  • Suprastin ( active substance chloropyramine) - in premature babies can cause retinal detachment, up to total loss vision;
  • Tavegil (active substance clemastine) - has a negative impact on the formation and development of the nervous system of the unborn child

Drugs that are subject to a relative ban include drugs containing:

  • loratadine - Claritin, Agistam, Lorano, Aleric;
  • fexofenadine - Altiva, Tigofast, Fexofast;
  • cetirizine - Allertec, Cetrin, Zodak.

And again we will not tire of repeating - no self-treatment! Taking all medications, even over-the-counter and completely harmless ones, only after agreement with the doctor!

Allergy Prevention

It is easier to prevent a disease than to treat it. In the case of allergies, this is quite difficult, because. it is often very difficult to determine exactly what exactly caused such a response of the body. You have to proceed by trial and error, and this takes a lot of time. For example, the author of the article was able to get rid of dermatitis only after a complete change in household chemicals, and it took about a year to understand that this particular measure helped. But that doesn't mean you shouldn't try. Here is a list of recommendations that help in most cases:

  • exclude from the diet foods that are considered allergens - honey, coffee, citrus fruits, smoked meats, canned food, strawberries, raspberries, pastries;
  • if you are allergic to pollen, leave your home less and do not go out of town during the flowering period. Try to use air conditioners, be sure to wash the filters in them at least once a month;
  • get rid of dust collectors in the apartment, which are traditionally carpets, books, soft toys. We do not call for throwing everything away, but putting all these things in boxes and plastic bags is quite within your power;
  • regularly do wet cleaning in the apartment, ventilate the rooms, wipe the dust.

Important! Try not to use household chemicals when cleaning;

  • do not keep animals and fish at home, refrain from visiting houses where there are animals.

Also good preventive measure in the fight against allergies, physiotherapy can become - halotherapy (sessions in salt room), electrophoresis, darsonvalization.

Be healthy!

mamapedia.com.ua

Treatment of allergies during pregnancy comes down to suppressing it. analog), at the rate of 1 tablet of the drug per 5 kg of human weight 2-3 times a day. the entire first trimester of pregnancy, then only on the recommendation of a doctor. 1 What you need to know about allergies during pregnancy. It is important to remember that in the first and third trimester, taking medications is extremely. Allergies during pregnancy can worsen, so the expectant mother. from taking medications - especially in the first trimester of pregnancy, when. Allergies during pregnancy develop in about 35% of women who. funds in the first trimester, because it is in the early stages that everything is laid. Each of these conditions has specific symptoms. If the disease appears within 1-2 months, it is recommended not to. Prevention and treatment of allergies during pregnancy. 2 and 3 trimesters);; allertec (after 14 weeks); pheniramine (after the end of the 1st trimester). Allergies during pregnancy Allergies are very unpleasant state organism, accompanied by specific symptoms. Dermatitis, rhinitis. Allergy during pregnancy is a common phenomenon, and its symptoms. In the 1st trimester, the placenta has not yet formed, which means that the fetus has no protection. 11 08 - 1 . soya | 11.11., 19:15:17 . You can drink medicines, but only as prescribed by the doctor with whom you are registered. I am allergic to citrus 9 months pregnant!!! what to drink, the doctor says zodak. It is possible that allergy medications can cause the decrease. The main thing in the treatment of allergies during pregnancy should not be. Go to the section Groups of antihistamines during pregnancy - Pregnant women from the 1st trimester. from allergies during pregnancy. Go to Trimester - It's hard to find allergy medications for children,. Treatment of orvi during pregnancy in the 1st, 2nd and 3rd trimester: what. Go to the section Antihistamines during pregnancy 1st trimester - Relief of allergic manifestations occurs during this period. 12 01 2007 — Global theoretical basis the use of drugs in Items 1, 2, and 3 imply inference: appoint a pregnant woman. 22 03 2016 - Allergy medicines for pregnant women. Author: Likar.info Friday, March 01, Rating: Worried about allergies during pregnancy. What are the causes of allergies during pregnancy? . I haven’t been able to get pregnant for 1.5 years, now it’s already the third month already.. Taking medications for allergies during pregnancy is a delicate topic. Each. Especially their reception can be unfavorable in the first trimester, when it comes. 16 04 - If necessary, it can be used in the treatment of acute allergic reactions in pregnant women in the II and III trimesters of pregnancy. Materials on the topic. Allergy during pregnancy: why does it appear and why is it dangerous? . 1st trimester: first 13 weeks of pregnancy. Especially dangerous. 31 08 — Why is allergy dangerous during pregnancy? . active substances(serotonin, histamine and others), causing symptoms allergies. home Allergy in mothers Ointment for allergies during pregnancy: how to relieve itching and irritation on the skin? . Medicines are very important in the treatment. ointments, if the allergy occurred in the 1st trimester of pregnancy. In that. 4 08 - Which allergy medications can be safely taken with. Washing the nasal cavity saline solutions 1-2 times a day can also help. Return to the section Second trimester of pregnancy. 7 02 2017 - During pregnancy, allergies may not make themselves felt (especially they pose a threat to the unborn child, especially in the first trimester. Safe medicines described in the table below. What to do if an allergy occurs in pregnant women? . 1 . Allergy on the face. These are small reddish dots or large ones. in the form of rashes, sometimes specific symptoms- flatulence,. A thick mop for a month. 13 07. 2017 - Antihistamines during pregnancy The appearance of allergic. Therefore, in the 1st trimester of pregnancy, the list of permitted .. But if the symptoms are found in a pregnant woman, the attending physician is obliged to. Tell! Who took Suprastin during pregnancy? . I suffer from allergies and at the beginning of my pregnancy

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Antihistamines during pregnancy. pregnancy and allergies

And although huge changes occur in the body of a woman with the onset of the period of bearing a peanut, the expectant mother does not always receive an unpleasant gift in the form of an allergy. If there is a predisposition to this disease, with the onset of the waiting period for the peanut, several scenarios are possible:

  • A new life - a baby in the mother's womb - does not affect the course of an allergy in any way. If a woman knows that certain products environment (cosmetics, household chemicals, some foods, etc.) cause her an atypical reaction, then it is enough for her to simply avoid contact with them.
  • During pregnancy, the intensity of allergic manifestations decreases. In some cases, an increase in the level of the hormone cortisol leads to the fact that the allergy "recedes".
  • Carrying a baby is accompanied by an increase in allergies. The increased load experienced by the body of a pregnant woman, in some cases, leads to an increase and exacerbation of diseases that were present even before the birth of a new life in the female womb. One such disease is bronchial asthma.

Triggering an allergic reaction

Why, in some cases, atopy is not long in coming, while other pregnant women do not even know what an allergy is? What triggers an allergic reaction?

  • The appearance of an allergen. An allergic reaction to something occurs as a result of contact with a provocateur component. The latter can be played as pollen, animal hair or insect venom, as well as a cosmetic or food product. Interaction with an allergen provocateur triggers a reaction, which results in an allergic response.
  • Repeated "meeting" with the allergen. It is no secret that acute atypical reactions (anaphylactic shock, Quincke's edema) occur almost immediately and after the first contact with the allergen. As for other manifestations of atopy, there is an accumulation effect, when, after a repeated encounter with an irritant, the production of antibodies begins and a response is formed.
  • Effect of antibodies on mast cells. As a result of the interaction of antibodies and mast cells, their contents are released from the latter, incl. histamine. It is he who is responsible for the appearance of a rash, lacrimation, edema, hyperemia and other "companions" of allergies.

Allergy symptoms during pregnancy

Depending on the causes that caused the allergic reaction, the following manifestations of atopy are possible:

  • Rhinitis. allergic rhinitis is the most frequent and common manifestation of allergies in expectant mothers. It is not seasonal and can occur from the first weeks of gestation. At the same time, congestion appears in the area of ​​​​the nasal passages, swelling of the nasal mucosa, there is a discharge of a watery mucous secretion, a burning sensation in the larynx may occur.
  • Inflammation of the mucous membrane of the eye - conjunctivitis. This manifestation of allergy in most cases is combined with a runny nose. There is swelling, hyperemia (redness), itching in the eyes and eyelids, lacrimation.
  • Urticaria - rashes on the skin in the form of blisters, accompanied by severe itching.
  • Symptoms of bronchial asthma.
  • In more severe cases - anaphylactic shock, Quincke's edema, which can lead to suffocation, extensive urticaria.

Manifestations of allergies can not only cause discomfort to a pregnant woman, but also pose a threat to the child in her womb, as there is a risk of oxygen starvation. Taking antihistamines during pregnancy is aimed at alleviating the manifestations of atopy, reducing the discomfort that they cause to a woman in position, and normalizing her condition as a whole.

Therapy for allergies

For effective fight with allergies and its manifestations A complex approach. It should include not only taking medications (if necessary), but also measures to prevent recurrence of the disease. The latter include nutritional correction if atopy is caused by food products, minimizing, or better, completely eliminating, contacts with an allergen - dust, animal hair, pollen, chemicals, cosmetic products. The largest number Questions and concerns in women are caused by the use of antihistamines during pregnancy. Therefore, to eliminate atopy, it is necessary to combine medication with folk methods to alleviate allergic reactions.

Antihistamines during pregnancy

When an allergy occurs in women in position drug therapy administered with extreme caution. The doctor assesses the severity of intoxication and determines the need for medical correction, because it is important not only to alleviate the condition future mother, but not harm the baby in her womb. What antihistamines can be used during pregnancy, and which therapy should be categorically abandoned even without regard to the waiting period for the baby?

Types of antihistamines

The development of antiallergic drugs has been going on for many years, and with each new generation of drugs, pharmacologists strive to increasingly reduce the level of toxicity of drugs, as well as to ensure the selective effect of their active ingredients. What antihistamines can be used by women during pregnancy? There are 3 generations of antihistamines:

  • 1 generation. Medicines of this group have the most extensive effect, therefore, not only block histamine receptors, but also affect the work of other body systems. Many of them have a sedative effect - cause a feeling of drowsiness, reduce the reaction. Among the side effects, dry mucous membranes are noted, there is a risk of developing heart defects on the part of the child. Medicines of this group - Suprastin, Diphenhydramine, Pipolfen (Diprazine), Tavegil, Diazolin, Zirtek, Allergodil.
  • 2 generation. Medicines of this group, like their predecessors, are also not particularly popular, since in varying degrees, but have a cardiotoxic effect. The difference is the absence of an inhibitory effect on the woman's nervous system. Among the drugs in this group, Claritin, Fenistil, Astemizol can be distinguished.
  • 3rd generation. This category of drugs included the most modern facilities, which have neither sedative nor cardiotoxic effects. However, even these drugs cannot be guaranteed safe for a pregnant woman and her baby. The drugs in this group include Desloratadine (Telfast, Eden, Erius), Feksadin.

The work of antiallergic drugs is directed in two main directions - the neutralization of histamine and the reduction of its production.

Antihistamines during pregnancy 1st trimester

As you know, the first weeks of bearing the crumbs are especially important, since it is during this period that the formation of the future person takes place. That is why even the most seemingly small interventions can have Negative consequences. Relief of allergic manifestations during this period occurs without the participation of pharmacological products. The exception is extremely severe cases that threaten the life of a woman or her baby. Therapy is prescribed strictly by a doctor and is carried out under medical supervision.

Antihistamines during pregnancy 2nd trimester

Stepping into the second trimester, thanks to the formed placental barrier, the baby becomes more protected from external influences, including from the influence of drugs that his mother is forced to take. However, most antihistamines that can relieve allergic manifestations, and during pregnancy, including, to a greater or lesser extent penetrate into the systemic circulation. During this period, medical correction of the condition is allowed, but carefully and strictly according to indications.

Antihistamines during pregnancy 3rd trimester

Despite the proximity of the birth of a peanut, the danger to the baby from the components of anti-allergic medicines still exists. If the woman's condition requires intervention, the doctor can prescribe the most benign drugs, taking into account the woman's situation. Before giving birth, taking antiallergic drugs should be stopped, as their action can suppress the work of the baby's respiratory center.

What antihistamines are allowed during pregnancy

The intervention of medicinal antiallergic drugs during the first weeks of gestation is highly undesirable. But already in the second and third trimesters, depending on the clinical manifestations, the doctor may prescribe a medical correction of allergic manifestations.

  • Suprastin. Not recommended for use in the first and third trimesters.
  • Zyrtec. The drug may be the choice of the doctor, as animal studies have not shown negative effects as a result of the use of the drug. Positioned women did not participate in the studies.
  • Cromolyn sodium will alleviate the condition with bronchial asthma. The drug is not recommended for use in the first 12 weeks of gestation.
  • Eden (Erius), Karitin and Telfast. The negative effect of the components of these medicines on the health of the mother and her child has not been proven, studies have not been conducted. Drugs can be prescribed strictly for health reasons.
  • Diazolin. It is acceptable to use the medication in the third trimester.

Some vitamins will also help reduce some manifestations of atopy:

  • Vitamin B5 (pantothenic acid). Helps to cope with allergic rhinitis.
  • Vitamin C (ascorbic acid). Reduces the susceptibility of the female body to respiratory manifestations allergies.
  • Vitamin PP (nicotinamide). Reduces manifestations of an atypical reaction of the body to plant pollen.

It should also be taken into account that the antiallergic drugs themselves can provoke atopy.

Antihistamines prohibited for use by pregnant women

A number of anti-allergic drugs are strictly prohibited for use by women in the position, regardless of the gestational age.

  • Tavegil. The medicine is categorically contraindicated, since experimental testing on animals has shown the development of pathologies.
  • Dimedrol. The medication is prohibited even in the later stages of waiting for the little one, as it can increase the uterine tone. As a result, the pregnancy may end prematurely.
  • Astemizol. The drug is contraindicated for use, as it has a toxic effect on the fetus (studies were conducted on animals).
  • Pipolfen. Medicine prohibited for use during the entire period of pregnancy.
  • Terfenadine. As a result of taking this tool the baby may lag behind in weight.
  • Feksadin. Use by pregnant women is prohibited.

Prevention of allergies during pregnancy

A few simple rules will help prevent the appearance of atopy:

  • Eliminate stress, try to devote sufficient time to walking, rest and relaxation.
  • If you have not yet acquired a pet, postpone this issue until the birth of the little one. If you already have a pet, it is better to give it to relatives or friends for a while.
  • Observe hypoallergenic diet. Watch what you eat and do not overdo it with allergenic foods (milk, honey, chocolate, citrus fruits, bright fruits and vegetables (eg strawberries, beets, eggs).
  • Perform regular wet cleaning and change of bed linen.
  • For the flowering period of "allergic" plants, it is advisable to leave, be careful about the indoor garden.

In the presence of skin manifestations allergies good help provide various talkers, ointments and decoctions prepared from the gifts of nature. Chamomile, calendula, celandine, nettle, succession, clay have proven themselves well.

Unfortunately, if preventive and folk methods do not bring long-awaited relief, taking antihistamines during pregnancy cannot be avoided. A consultation with a doctor and a competent risk assessment will allow you to choose the best therapy.

beremennuyu.ru

Permitted drugs during pregnancy: what drugs can I drink?

Allergies are faced by a huge number of people. Men and women of any age are ill, children are highly susceptible to allergic reactions. Therefore, research in this area and the development of new drugs is very active.

Vitamin preparations for allergies

Do not forget that not only antihistamines, but also some vitamins can help in the fight against allergy symptoms. And pregnant women usually have a more trusting attitude towards them.

  • vitamin C can effectively prevent anaphylactic reactions and reduce the incidence of respiratory allergies;
  • vitamin B12 is recognized as a powerful natural antihistamine, helps in the treatment of dermatosis and asthma;
  • pantothenic acid (vit. B5) will help in the fight against seasonal allergic rhinitis and a reaction to household dust;
  • Nicotinamide (Vit. PP) relieves attacks of spring allergy to plant pollen.

Traditional antihistamines: allergy pills

Newly emerging drugs are effective and do not cause drowsiness. However, many doctors are trying to prescribe more traditional remedies for pregnant women.

For drugs that have been on the market for 15-20 or more years, enough statistical data has been collected to talk about their safety or negative impact on the health of the fetus.

Suprastin

The drug has been known for a long time, it is effective for various manifestations of allergies, it is allowed for both adults and children, and therefore it is also allowed for use during pregnancy.

In the first trimester, when the fetal organs are forming, this and other drugs should be taken with extreme caution, only in case of emergency. In the rest of the period, suprastin is allowed.

Advantages of the drug:

  • low price;
  • speed;
  • effectiveness in various types of allergies.

Flaws:

  • causes drowsiness (for this reason, it is prescribed with caution in the last weeks before childbirth);
  • causes dry mouth (and sometimes mucous eyes).

Diazolin

This drug does not have such speed as suprastin, but effectively relieves the manifestation of chronic allergic reactions.

It does not cause drowsiness, therefore, there are restrictions in the appointment only in the first 2 months of pregnancy, in the rest of the period the medicine is approved for use.

Advantages of the drug:

  • affordable price;
  • a wide range of activities.

Flaws:

  • short-term effect (requires taking 3 times a day).

cetirizine

Refers to the new generation of drugs. It can be produced under different names: Cetirizine, Zodak, Allertec, Zyrtec, etc. According to the instructions, cetirizine is prohibited for use during pregnancy and lactation.

Due to the novelty of the drug, there is not enough data on its safety. But, nevertheless, it is prescribed to pregnant women in the 2nd and 3rd trimester in situations where the benefits of taking it significantly outweigh the risk of side effects.

Advantages of the drug:

  • a wide range of activities;
  • speed;
  • does not cause drowsiness (except for individual reactions);
  • reception 1 time per day

Flaws:

  • price (depending on the manufacturer);

Claritin

The active substance is loratadine. The drug can be produced under different names: Loratadin, Claritin, Clarotadin, Lomilan, Lotharen, etc.

The same as that of cetirizine, the effect of loratadine on the fetus has not yet been sufficiently studied due to the novelty of the drug.

But studies conducted in America on animals have shown that the use of loratadine or cetirizine does not increase the number of pathologies in the development of the fetus.

Advantages of the drug:

  • a wide range of activities;
  • speed;
  • does not cause drowsiness;
  • reception 1 time per day;
  • affordable price.

Flaws:

  • used with caution during pregnancy.

Feksadin

Refers to the new generation of drugs. It is produced in various countries under a different name: Feksadin, Telfast, Fexofast, Allegra, Telfadin. You can also meet the Russian analogue - Gifast.

In studies on pregnant animals, fexadine showed the presence of side effects with long-term use at high doses (increased mortality due to low fetal weight).

However, no such dependence was found when administered to pregnant women.

Advantages of the drug:

  • wide spectrum of action
  • performance
  • reception 1 time per day.

Flaws:

  • with caution is prescribed during pregnancy;
  • effectiveness decreases with prolonged use.

Fenistil

The drug in the form of capsules is currently not available on the Russian market. In pharmacies there are drops for oral administration and gels for external use.

The drug is approved for use in infants, and therefore is often prescribed for pregnant women.

Gel for local treatment can be used without fear, it is practically not absorbed, does not enter the bloodstream. Fenistil is a part of antiherpetic emulsions.

Advantages of the drug:

  • safe even for babies;
  • average price range.

Flaws:

  • not a very wide spectrum of action;
  • limited release forms;
  • side reactions are possible.

These drugs differ in price and form of release (tablets for daily use, injections for emergency cases, gels and ointments for topical use, drops and syrups for children)

Name of the drug Release form, dosage Volume/quantity price, rub.
Suprastin Tablets 25 mg 20 pcs 150
Injection 5 ampoules of 1 ml 150
Diazolin Dragee 50/100 mg 10 pieces 40/90
cetirizine Cetirizine Hexal tab. 10 mg 10 pieces 70
Cetirizine Hexal drops 20 ml 250
Zyrtec tab. 10 mg 7 pcs 220
Zyrtec drops 10 ml 330
Zodak tab. 10 mg 30 pcs 260
Zodak drops 20 ml 210
Claritin Loratadine tab. 10 mg 10 pieces 110
Claritin tab. 10 mg 10 pcs/30 pcs 220/570
Claritin syrup 60ml/120ml 250/350
Clarotadine tab. 10 mg 10pcs/30pcs 120/330
Clarotadine syrup 100 ml 140
Feksadin Feksadin tab. 120 mg 10 pieces 230
Feksadin tab. 180 mg 10 pieces 350
Telfast tab. 120 mg 10 pieces 445
Telfast tab. 180 mg 10 pieces 630
Fexofast tab. 180 mg 10 pieces 250
Allegra tab. 120 mg 10 pieces 520
Allegra tab. 180 mg 10 pieces 950
Fenistil Drops 20 ml 350
Gel (external) 30g/50g 350/450
Emulsion (external) 8 ml 360

Antihistamines with fetal side effects

Previously used antihistamines had a significant sedative effect, some also have a muscle relaxant effect. In some cases, it was useful in the treatment of allergies and even relieved nausea, but the effect on the fetus can be extremely negative.

It will be difficult for a lethargic and “sleepy” child to take his first breath, this threatens with aspiration, possible pneumonia in the future.

The intrauterine effect of these drugs can manifest as fetal malnutrition, which will also affect the activity of the newborn baby.

  • Diphenhydramine

can increase uterine tone, cause premature contractions

  • Tavegil

has a negative effect on fetal development

  • Pipolfen
  • Astemizol (Histalong)

affects liver function, heart rate, has a toxic effect on the fetus

In order to avoid harmful effects on the fetus, antihistamines are not recommended for pregnant women during the first trimester. During this crucial period, when all the organs of the unborn child are being formed, the placenta has not yet been formed, and substances entering the mother's blood can affect the health of the fetus.

Medicines during this period are used only in case of a threat to the life of the mother. In the second and third trimester, the risk is less, so the list of acceptable drugs can be expanded.

However, in any case, preference is given to local and symptomatic treatment, antihistamine tablets are prescribed in small doses and for a limited period.



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