Imodium fast acting diarrhea tablets. How to use Imodium: instructions and special instructions. What to do in case of overdose

It’s unlikely that anyone doesn’t know what Imodium helps with, because these capsules are in every second person’s medicine cabinet. In case of an unexpected attack of diarrhea, having tablets in your purse is invaluable.

Despite the fact that the cost of this drug is much higher than its analogues, the speed of action of the active substance is also highly responsive.

Release form, composition and packaging

Imodium comes on the shelves in the form of tablets that must be dissolved, as well as gelatin-coated capsules.

In any of the indicated options, one unit contains 2 mg of the main substance - loperamide hydrochloride.

In addition, there are additional components - mint flavor, gelatin and aspartate.

Tablets are packaged in packs of 10 or 20 pieces.

In addition to the active substance, the Imodium capsule contains:

• talc;
• corn starch);
• lactose particles;
• magnesium stearate;
• talc.

Capsules are formed into plates of 10 pieces; the box may contain a couple of blisters.

pharmachologic effect

1. Imodium is an antidiarrheal drug, the main substance of which acts as an inhibitor of opioid receptors. Laboratory tests revealed an active effect on the tissues of the intestinal walls. Prostaglandins and acetylcholine in the gastrointestinal tract are blocked due to the functioning of various groups of neurons.
2. Taking Imodium provokes an increase in the tone of the sphincter and rectum. The need to have a bowel movement becomes less frequent due to decreased intestinal motility. Feces travel through the gastrointestinal tract for a longer period of time. Reducing mucus in the intestinal lumen is achieved by reducing its secretion. Moreover, the liquid is absorbed faster, reducing the risk of dehydration. With diarrhea, electrolyte imbalance is common, which can be treated with Imodium.
3. The main component of the drug fights pain well, which can occur due to spasms in the muscles of the intestinal walls.
4. The effect of Imodium is achieved in a short time, since the absorption of the drug is very high. Digestion occurs in the liver and is excreted from the body in feces or bile.

Indications for use

Imodium is prescribed for various situations when stool adjustment is required.

It is considered appropriate to carry out drug therapy if the following is diagnosed:

• acute or chronic diarrhea;
• traveler's diarrhea (treatment lasts at least 2 days);
• food poisoning;
• rotavirus infection;

Moreover, it is considered advisable to use Imodium if the patient complains of frequent heartburn, nausea or severe vomiting.

Contraindications for use

Imodium, like any other drug, has a number of contraindications that cannot be ignored.

Below is a list of the most important ones:

• volvulus;
• personal intolerance to the components of the drug;
• colitis of ulcerative type at the stage of relapse;
• diverticulosis;
• infectious diseases (for example, botulism, dysentery, etc.);
• the period of breastfeeding and the initial trimester of pregnancy;
• pseudomembranous enterocolitis.

Also, children under 2 years of age cannot use Imodium in forms other than solution. From 5 years of age, it is permissible to prescribe capsules for resorption.

Instructions for use

Each case of the disease is considered individually; self-medication is prohibited.

An acute attack of diarrhea is observed more carefully; if the patient does not respond to treatment after 2 days, it is recommended to stop using Imodium and select another medication. If normal stool is observed or if it is absent for more than 12 hours, it is also recommended to discontinue Imodium.

Application for children

Despite the prohibitions of specialists that it is forbidden to give various drugs to children, women often begin self-treatment for diarrhea in children. Such behavior is prohibited and can threaten a sharp deterioration in general condition.

For this reason, when therapy using Imodium, it is recommended to adhere to certain rules:

• The dosage is calculated based on the weight and height of the baby; the pediatrician is obliged to indicate the exact parameters so as not to make mistakes when prescribing the medicine.
• Provided that Imodium is prescribed in drops, the amount of the drug is always diluted with a small spoon of warm water. Only after this is the medicine given to the child.
• The younger group of patients often refuses to take pills. Imodium can be diluted in juice or weak tea. But the amount of additional drink does not exceed the volume of a regular spoon.
• Imodium, which is produced in drops for resorption, is prescribed to children who have already crossed the threshold of 5 years.

The home first aid kit should be kept in a place where the child has no access. Moreover, the medicine has a pleasant mint smell and a slightly sweet taste. Therefore, children mistake Imodium for candy and can become poisoned by the drug.

Use during pregnancy and breastfeeding

Imodium should not be used during the first stage of pregnancy.

The reason is that at this moment the child’s internal organs are being formed and any medicinal effect can make negative adjustments.

At a later stage of pregnancy, treatment with Imodium is considered justified if the benefits of the drug are higher than the risk to the health of the baby.

Due to the high degree of absorption of the drug, it is not worth taking Imodium during lactation. If the product passes into breast milk, it is considered dangerous.

Side effects

Despite a number of positive qualities, Imodium is capable of provoking the formation of an undesirable reaction during therapy.

Patients may experience:

• rash on the skin, similar to hives;
• persistent drowsiness and dizziness due to a malfunction in the electrolyte balance;
• nausea, vomiting;
• problems with bowel movements, lack of stool, bloating;
• intestinal colic, discomfort in the abdominal cavity and lower abdomen;
• dryness of the oral mucosa;
• in some cases, problems with urination or intestinal obstruction are noted.

After dissolving mint tablets, some patients felt burning and itching under the tongue, as well as on its surface.

It is worth noting that a severe adverse reaction occurs only in a small percentage of patients. Others tolerate Imodium quite well. If there are pathological symptoms during treatment, then stop taking the medication and consult a doctor.

Overdose

Intoxication when taking Imodium can occur in some situations:

• self-medication with the drug and choosing the wrong dosage, frequent use of capsules;
• absorption of pills by a child who, due to the unusual taste, mistook the medicine for candy;
• deliberately overestimating the dose to get rid of an attack of diarrhea more quickly.

If there is an excess amount of Imodium in the body, the patient experiences toxic damage.

It is manifested by the occurrence of the following symptoms:

• problems with coordination;
• muscle ailments, drowsiness;
• blood pressure surges;
• depression of the respiratory system.

If a patient is diagnosed with severe drug poisoning, intestinal obstruction may occur.

In order to stop an overdose of Imodium, you will need to rinse the stomach cavity, use an antidote and take sorbents. Often, the patient is administered Naloxone, which helps to improve the condition already when the initial stage of an overdose is detected.

Interaction with other drugs

There are no special instructions on this matter from doctors, since Imodium is distinguished by its safety. However, with the simultaneous use of an antidiarrheal agent and cholestyramine, the effectiveness of the former may be significantly reduced.

The bioavailability of Imodium is affected by its parallel administration with Trimaxazole and Ritonavir. This phenomenon was noticed due to the pronounced inhibition of the metabolism of the anti-diarrhea drug during the initial passage of liver tissue.

Otherwise, no complications or adverse reactions were identified during combination treatment or other therapy.

Alcohol compatibility

Imodium should not be combined with alcohol-containing drinks, as it causes depression of the central nervous system and brain cells. Also, there is an increased load on the liver, which is detrimental to its functioning. Patients' general condition worsens and drowsiness appears.

Use for liver and kidney dysfunctions

Patients with severe liver failure must be under constant medical supervision. This measure is required due to possible toxic damage to the central nervous system. When pathological processes are identified, auxiliary therapy is carried out.

Use in elderly patients

Therapy for people in the older age group does not differ from the general guidelines. The dosage is calculated strictly according to the instructions. In the absence of individual intolerance and concomitant diagnoses, treatment with Imodium occurs without adverse reactions.

Application for weight loss

Namely, Imodium is not used as a drug that will help you lose weight. An anti-diarrhea remedy cannot save you from obesity, because it has other tasks. But it acts as an auxiliary tool quite often.

When getting rid of extra pounds, many women have problems with bowel movements, and diarrhea can become a constant companion.

To adjust the frequency of the urge to go to the toilet and avoid diarrhea due to the specific nature of limited nutrition, Imodium is used. Usually a standard dosage is enough to forget about the problem in the future.

Use for prevention

To maintain good health and to avoid recurrence of diarrhea, doctors advise taking Imodium even after the attacks have stopped.

The dosage of the drug is adjusted taking into account bowel movements twice in 24 hours.

Typically, the daily dose of Imodium for an adult does not exceed 6 capsules.

The maximum permissible increase in the number of pills is a couple of units.

special instructions

To achieve maximum effect, it is advised to adhere to a number of rules when carrying out Imodium therapy:

1. The maximum waiting period for improvement is 2 days. If after the expiration of the period there is no relief of symptoms, then it is suggested to consult a doctor for diagnostics with subsequent diagnosis.
2. Children under 5 years of age are considered a limitation for the use of Imodium capsules. In this case, it is recommended to use the medicine in the form of a solution or lozenges.
3. If the patient experiences bloating or constipation, therapy should be stopped.
4. Diarrhea is accompanied by significant loss of fluid from the body, this means that the patient needs to drink plenty of fluids. Due to a failure to replenish the electrolyte balance, experts advise using rice water or rehydron.
5. People who will drive a car in the future, or perform work that requires increased concentration, must take into account the fact that the overall reaction will be reduced.

Conditions for dispensing from pharmacies

To purchase Imodium, you do not need a prescription; the pharmacist sells the medicine without requiring a prescription from a specialist.

Storage conditions and shelf life

Imodium is in the first aid kit, which should not be in the public domain of children. The storage temperature ranges from 14 to 29 degrees.

The shelf life of the drug allowed by the manufacturer is 5 years., if the conditions for its storage were not grossly violated.

After the expiration date, Imodium should not be used, as this can have serious consequences.

Prices

Imodium capsules or tablets can be found in any pharmacy chain. The cost of a package with 6 capsules will cost 160 rubles. This price applies to the drug, which is sold in Moscow and other cities of central Russia.

The release form in the form of lozenges will cost 10-20 rubles more expensive. Since the performance of this option is slightly higher.

Analogs

There are 2 types of medications that can replace Imodium in the treatment of diarrhea. Some will be completely identical, while others will differ in composition, but are similar in their influence.

A list of popular analogues is given below:

1. Levomycetin. Considering that this is an antibiotic with a wide spectrum of influence, the greatest effect is achieved with diarrhea that occurs after infection by microorganisms. Price less 50 rubles.
2. Smecta. Despite the fact that the medicine is used for diarrhea, the therapeutic effect for this problem is weak. Since Smecta has a greater effect on the organs of the digestive tract. The cost of the product is approx. 30 rubles per bag.
3. Stopdiar. They are used for almost all types of diarrhea and are not inferior to Imodium in effectiveness. Capsules are taken every 6 hours to quickly stop the frequent urge to urinate. The amount for the drug reaches 300 rubles.
4. Phthalazol. Helps with infectious diarrhea; to improve the condition, therapy is required, which lasts at least 3 days. Budget product, packaging will cost 15 rubles.
5. Diara. Chewable capsules that quickly provide relief to the patient and retain their effect for about 5 hours. An adult only needs 2 tablets per dose to feel improvement. Price approx. 95 rubles.

Synonyms for Imodium, that is, medications that have one active ingredient, are:

1. Loperamide. One of the cheapest products that has been used by specialists for a long time. The cost of packaging will not exceed 12 rubles.
2. Lopedium. A more expensive option, although cheaper than Imodium. For a box of medicine they will charge about 50 rubles.
3. Loperamide hydrochloride. Also refers to varieties of Imodium, but with a weaker effect on the body. Price per package approx. 24 rubles.

All options from the group of Imodium synonyms are domestic, which is why they have such a low cost.

The medicinal drug Imodium is a powerful tool in the fight against diarrhea, both chronic and acute. This drug is also successfully used as a component of complex therapy for infectious pathologies accompanied by intestinal disorders. The product helps slow down peristalsis and increase the tone of the anal sphincter. Imodium is available in pharmacies without a prescription, but it is strongly recommended that you consult with a specialist before starting use. The product can also be used for preventive purposes.

Dosage form

The most common form of release of the drug Imodium is round lyophilized tablets for resorption, almost white or completely white. Primary packaging consists of aluminum blisters of six or ten units. Secondary packaging is cardboard packs containing one (6 and 10 tablets) or two (10 tablets) blisters. Less popular versions of the drug also exist in the form of chewable tablets, capsules, or oral solution.

Description and composition

The main active element of the drug Imodium is hydrochloride. The active substance content per tablet is two milligrams.

The composition of the medication includes the following auxiliary elements:

• aspartame;
• gelatin;
• mint flavor;
• mannitol;
• sodium bicarbonate.

Pharmacological group

The drug Imodium belongs to the group of antidiarrheal medications. Hydrochloride, which is the active substance of the drug, significantly slows down intestinal motility, which occurs by blocking the release of prostaglandins and acetylcholine. This effect is achieved through the directed influence of the active component directly on the opioid receptors of the intestinal walls. Taking therapeutic doses of the drug helps strengthen the smooth muscles of the rectum and increases the tone of the anal sphincter, which significantly reduces the frequency of the urge to defecate and improves the duration of fecal retention. In turn, decreased peristalsis leads to a slower passage of intestinal contents.

Another effect of hydrochloride is the suppression of mucus secretion in the intestinal lumen. Also, taking the drug improves absorption in the gastrointestinal tract and reduces pain during intestinal spasms of smooth muscles.

The active element of the drug Imodium is easily absorbed from the gastrointestinal tract, as a result of which the therapeutic effect quickly manifests itself. Binding to blood plasma proteins (albumin) is 95–97%. Metabolism occurs primarily in the liver. The half-life is from 9 to 14 hours. Excreted in feces and bile.

Indications for use

Imodium is used to treat acute or chronic manifestations of diarrhea of ​​various origins. Hydrochloride provides quick and effective relief from symptoms of intestinal upset, relieves pain and helps restore electrolyte balance in case of dehydration.

for adults

The main indications for medicinal and prophylactic use of the drug Imodium are the following:

• symptomatic treatment of chronic or acute diarrhea;
• intestinal disorders due to infectious pathologies;
• regulation of stool after an ileostomy procedure;
• irritable bowel syndrome;
• ulcerative colitis (as a component of complex treatment).

Most often, Imodium is prescribed to patients suffering from diarrhea caused by the following factors:

• disturbances of normal metabolism;
• radiation therapy;
• constant stress;
• broken power supply;
• consumption of stale food;
• allergic reactions.

for children

Therapeutic or prophylactic use of the drug Imodium is permitted only for children over six years of age. The list of indications for use is the same as for adult patients. Children aged six to eighteen years should take this medication only under the supervision of a physician.

There are no data on studies on the negative impact of the active element of the drug Imodium on fetal development. However, taking the product is strictly prohibited. During the second and third trimesters, the use of a medication is justified only if the expected benefit for the woman significantly exceeds all possible risks to the health of the fetus. In this case, strict supervision by a specialist is necessary.

Due to the possibility of hydrochloride passing into breast milk, it is not recommended to use Imodium during lactation. However, in cases where the use of a medication is absolutely necessary, the drug can only be used if the child is completely and immediately stopped breastfeeding.

Contraindications

The most common prohibitions on the therapeutic or prophylactic use of Imodium are conditions such as:

• children under 6 years of age;
• individual intolerance or hypersensitivity to elements of the drug;
• acute form of dysentery (in the presence of fever and bloody stools);
• enterocolitis of bacterial origin;
• breastfeeding period;
• exacerbation of ulcerative colitis;
• lactose intolerance;
• pseudomembranous colitis, which manifested itself while taking antibacterial medications;
• paralytic ileus.

Imodium is not recommended for use during the second and third trimesters of pregnancy without constant medical supervision. If characteristic bloating appears, as well as difficulty in defecation, the drug should be stopped immediately.

Patients suffering from various liver dysfunctions should be careful when using this drug.

Applications and dosages

Imodium should be taken immediately after each bowel movement if the stool is liquid. To do this, you need to put the tablet on your tongue, wait a few seconds and swallow it along with saliva. It is not recommended to drink the product with water. After the patient’s condition has normalized or there has been no bowel movement for twelve hours, the medication should be discontinued.

for adults

When treating acute diarrhea, the initial dose should be four milligrams (2 tablets), after which it is recommended to take two milligrams (1 tablet) after each unformed stool.

For the treatment of chronic diarrhea, the dosage is selected by the doctor individually based on the nature of the pathology and the presence of concomitant disorders. However, the first dose of Imodium should also be 2 tablets.

The maximum amount of the drug per day should not exceed 12 mg (6 tablets).

for children

For children over 6 years of age, the initial and subsequent dosages of Imodium should not exceed 2 mg (one tablet) after each loose bowel movement. The maximum daily intake should be 3 tablets of the product for every 20 kg of the child’s weight. However, taking more than six tablets per day is strictly prohibited.

for pregnant women and during lactation

In the second and third trimesters of pregnancy, an individual calculation of the dosage of the medication is necessary. In the first trimester and during breastfeeding, the use of Imodium is contraindicated. The contraindication is due to the ability of the substances included in the product to penetrate into mother’s breast milk.

Side effects

Among the most common side effects associated with the use of Imodium are:

• dry mouth;
• headache and dizziness;
• nausea;
• urinary retention;
• seizures;
• sleep disturbance and anxiety;
• burning or tingling sensation on the tongue;
• difficulty breathing;
• pain and discomfort in the abdominal area;
• flatulence.

If a clear clinical picture occurs after taking Imodium, seek help from a specialized institution.

Interaction with other drugs

With the simultaneous use of cholestyramine and Imodium, the effectiveness is inhibited. Ritonavir and co-trimoxazole increase the bioavailability of the drug. In case of Imodium intoxication, the use of naloxone is recommended.

special instructions

If the therapeutic effect does not occur after 48 hours of continuous use, it is necessary to clarify the diagnosis. During treatment, it is imperative to replenish fluid and electrolyte losses.

During the therapy period, you should be careful when driving a car, playing extreme sports and working with dangerous mechanisms.

Overdose

When intoxicated with Imodium, the following symptoms are observed:

• stupor;
• violation of spatial orientation;
• constriction of the pupil;
• dizziness;
• hypertension of muscle fibers;
• drowsiness;
• difficulty breathing;

To eliminate the consequences of Imodium poisoning, it is necessary to carry out symptomatic therapy. However, before this, it is recommended to take a large amount of sorbent and rinse the stomach.

Analogs

You can replace Imodium with the following medications:

1. is a complete analogue of Imodium. This is a drug from Sandoz, which costs less than the original drug, but the generic is of good quality. Available in tablets and capsules that can be prescribed to patients over 6 years of age. It should not be taken during lactation.
2. Diara is available in chewable tablets and capsules, which contain as an active ingredient. The drug should not be prescribed to children under 6 years of age, in the first 13 weeks of pregnancy, or during the entire period of breastfeeding.
3. Imodium Plus is available in the form of chewable tablets. Its active ingredients are and. The drug is recommended as an antidiarrheal agent for patients over 12 years of age when indigestion is accompanied by bloating.
4. contains diosmectite as an active component. The drug is produced in powder, from which a suspension is prepared for oral administration. The medicine comes in vanilla, orange, and caramel flavors. The medicine is available to all groups of patients.

Storage conditions

Imodium should be stored out of the reach of children at room temperature and in relatively dry air.

Shelf life – 5 years.

Price

The cost of Imodium is on average 371 rubles. Prices range from 164 to 870 rubles.

Imodium is a drug produced in capsule form. For acute diarrhea, it is preferable to use Imodium in the form of lozenges. Thank you for explaining in detail how this Imodium works.

Imodium ® (lat. Imodium ®) is an antidiarrheal drug. Imodium comes in two dosage forms: capsules and lozenges, also called lingual tablets. Imodium (lomeramide) is the drug of choice for the treatment of traveler's diarrhea. For secretory diarrhea, Imodium is also very effective due to its antisecretory opiate-like effect.

How to take Imodium: rules and warnings

The information presented in this section about medications, diagnostic and treatment methods is intended for medical professionals and does not constitute instructions for use. Imodium (lomeramide) is an effective remedy for acute diarrhea of ​​a non-infectious nature, as well as for infectious diarrhea of ​​mild and moderate severity.

Loperamide increases the tone of the anal sphincter, resulting in a decrease in the frequency and severity of the urge to defecate. Loperamide reduces mucus hypersecretion in the colon, and also has an antisecretory effect, which is realized through both opioid and non-opioid receptors. Moreover, in these situations it can worsen diarrhea. For infectious diarrhea, Imodium should be prescribed with caution, since the retention of the infectious agent in the body increases diarrhea and intoxication.

If normal stool appears or if there is no stool for more than 12 hours, the drug is discontinued (Instructions for use). The WHO training manual “Treatment of diarrhea”, 2006, notes that Imodium, as “... and other inhibitors of intestinal motility may reduce the frequency of bowel movements in adults. None of these drugs should be given to infants and children with diarrhea."

The composition of Imodium and its effect

Loperamide, which is part of the drug, takes effect an hour after use. The active substance of the drug (Loperamide) is easily excreted from the intestines, completely absorbed by the liver and excreted in the bile. In the USA in 1973, the drug was patented and it became known under the brand name IMODIUM®. At the moment, it is the only drug containing Loperamide in this form (among its analogues).

Find out more about the drug IMODIUM®, the principle of its action and the history of the drug’s appearance in the world and in Ukraine. IMODIUM® should be used to treat acute and chronic diarrhea and in cases of traveler's diarrhea. If symptoms persist for more than 48 hours, you should consult a doctor. To establish a diagnosis and prescribe a course of treatment, you must consult a doctor.

Indications for use:

The effect of imodium is associated with the effect of its active component, loperamide, on nerve cells. Feces are retained in the intestines, while partial reabsorption of water and salts into the blood occurs and dehydration is prevented.

For all chronic diseases and intestinal conditions, Imodium can only be prescribed by a doctor who selects an individual dose of the drug and monitors the patient’s condition. If the patient shows signs of drug overdose, intestinal obstruction or intestinal infection, Imodium is discontinued. Some resort to emergency treatment with widely advertised medications, such as the popular Imodium.

A spoiled and contaminated product, which contains pathogenic microorganisms and the dangerous toxins they produce, is eaten by an adult or child. In the stomach, under the influence of hydrochloric acid, microbes may die, but the toxins are not neutralized, unfortunately.

The pharmaceutical industry has been producing Imodium for over 30 years. It comes in capsules that must be swallowed and washed down. Another more convenient form, especially on the road, is round tablets of white color and mint taste, they need to be dissolved.

Briefly about food poisoning and intestinal infections

The drug relieves pain associated with spasms in the intestines. The medicine begins to act within half an hour. Imodium has no effect on pathogenic bacteria. With diarrhea, microbes and their toxic products are present in the intestines.

There is no need to grab Imodium yet if diarrhea occurred due to taking antibiotics - then complications may arise against the background of dysbacteriosis. Imodium or its synonym Loperamide, which costs less, are often found in home or travel first aid kits. They are used by many because they are easy to use. People think that they can resort to these drugs in any case of diarrhea without fear.

Now it is clear that you still need to drink something else against intestinal microbes, or Imodium in extreme cases, if you really are traveling in transport. This drug acts on the intestinal muscles and slows down the movement of its contents. What medicine will quickly and effectively help against diarrhea? In this article you can read the instructions for using the drug against indigestion.

This is a fairly well-known and effective antidiarrheal drug that has found wide use throughout the world. The manufacturer of this drug is Janssen.

However, as for newborns, this drug paralyzes their intestinal muscles. As a result, most children die. A similar tragedy occurred in Pakistan. Many experts argue that children's Imodium should no longer be supplied to pharmacies.

That’s when many people pull out pre-stocked Imodium tablets or other drugs or its analogues from their purse. But in such situations it is still undesirable to use Imodium. To prevent this from happening, it is better to take Imodium as prescribed by a doctor, despite the fact that this drug is sold in pharmacies without a prescription.

Imodium: instructions for use

How does Imodium work?

In the classification of drugs, the drug belongs to the antidiarrheal group. Loperamide reduces the motor activity of the muscular wall of the intestine and increases the tone of the anal sphincter (the muscular ring that locks the rectum), thereby slowing down the passage of contents through the intestinal tube. The effect occurs within half an hour after administration and lasts up to 6 hours.

Dosage of the drug

Imodium is available in capsules and tablets of 2 mg. For adults and children over 12 years of age, it is recommended to start with 4 mg for diarrhea, then another 2 mg after each episode of diarrhea. The maximum permissible dose for adults is 16 mg per day, and for children - 6 mg per 20 kg of body weight up to 16 mg. In children it is approved for use from 4 years of age at the following dose:

• from 4 to 8 years: 1 mg up to 4 times a day for 3 days;
• from 9 to 12 years: 2 mg up to 4 times a day for 5 days.

Mode of application

Imodium capsules are taken orally half an hour before meals. Lozenges are placed on the tip of the tongue. Within a few seconds, the tablet dissolves and can be swallowed without drinking water. Stop taking the drug when formed stool appears or if there is no urge to defecate for more than 12 hours.

Use during pregnancy and lactation

Imodium during pregnancy is contraindicated in the first trimester, when the newly developing tissues and organs of the fetus are most susceptible to all influences, including medications. If it is necessary to take it in the second and third trimesters, the issue of prescription is decided individually with the attending physician in order to adequately assess the benefits for the mother and the possible risk for the baby. A small amount of the active substance is found in breast milk, so taking the drug is not recommended during breastfeeding.

Indications for use

Imodium is prescribed for the symptomatic treatment of diarrhea, i.e. the drug does not affect the cause of the pathology that has arisen, but only counteracts the unpleasant sign of the disease:

• allergic diarrhea;
• upset bowel movements due to emotional reasons;
• loose stools as a side effect of taking other medications;
• radiation diarrhea;
• when changing diet and diet composition;
• in case of disruption of absorption processes in the small intestine;
• for infectious diarrhea - only as an adjuvant;
• in patients with ileostomy - to regulate stool frequency.

Contraindications

There is a list of conditions for which Imodium should not be used:

• intestinal obstruction;
• constipation;
• flatulence;
• acute ulcerative colitis;
• pseudomembranous colitis as a result of taking certain antibiotics (lincomycin, clindamycin, less often penicillins and cephalosporins);
• age under 4 years, and in capsules – under 6 years;
• pregnancy at less than 13 weeks.

Loperamide or Imodium – which is better?

The active ingredient in the drug under the trade name Imodium is loperamide. Imodium is an original drug, that is, it is produced by the same pharmaceutical company that developed and researched it. In addition, there are generics on the market - medicines with a similar composition and instructions for use, but they are produced by other manufacturers:

• Loperamide (Russia, Ukraine, Latvia);
• Vero-Loperamide (Russia);
• Diara (Russia);
• Lopedium (Slovenia, Germany, Switzerland);
• Superilop (India).

They are significantly cheaper than their prototype, since the company does not need to recoup the costs of the invention and clinical testing of the chemical formula. Nevertheless, any practicing doctor confidently recommends the original drug, since it is more effective than analogues and is less likely to cause side effects. This is due to the release form and the quality of the excipients that are inevitably included in the tablet or capsule.

What is Imodium Plus?

Imodium Plus is a multicomponent drug that contains two active ingredients - loperamide and simethicone. Simethicone is an antifoaming agent used to relieve increased gas formation and bloating, which are often observed when taking loperamide. Imodium Plus has similar indications and contraindications for use, but is approved only for patients over 12 years of age.

Features of taking the medicine

If diarrhea occurs, it is advisable to consult a specialist so as not to worsen the condition. If symptoms do not subside within 2 days of self-treatment, be sure to consult a doctor to determine the cause of the disease and receive the necessary recommendations for treatment.

With diarrhea of ​​any origin, the body loses water and salts, so they need to be replenished by taking a sufficient amount of fluid - preferably saline solutions (such as Oralit, Regidron). This is especially important in case of poisoning, when drinking plenty of fluids is intended not only to cover the body’s costs, but also to dissolve and remove toxins from the bloodstream. You can independently prepare a solution similar to physiological (0.9% sodium chloride), for which a teaspoon of coarse table salt (it does not contain an anti-caking agent) is dissolved in 1 liter of boiled or bottled water at a temperature of 37 - 40 ° C.

Remember that if a child has an intestinal infection, his condition may worsen sharply. Children become dehydrated faster, tolerate intoxication more severely, and shock can develop—a life-threatening drop in blood pressure. They are more likely to vomit, making it difficult to give them enough liquid to drink. In this case, the baby needs intravenous administration of saline solutions and medications. If your child experiences diarrhea or vomiting, be sure to consult your pediatrician. If the doctor considers hospitalization necessary, do not refuse - delay could cost the baby his life.

Use caution when performing activities that require increased alertness and reaction, including driving. Loperamide may cause drowsiness, loss of coordination, stupor, and depression of consciousness. If these symptoms appear, stop taking the drug and seek help from a specialist.

Any disease can be treated more effectively with an integrated approach - it is not enough just to take a remedy for diarrhea. If we are talking about an intestinal infection (salmonellosis or dysentery), the first place is taken by an antibacterial drug; in case of an allergic infection, the search for and exclusion of the intolerable product from the menu comes first. The doctor will draw up a detailed treatment plan and explain how to take this or that drug.

Learn how to take Imodium for diarrhea

Intestinal disorders can occur suddenly, ruining all your plans for the day. Especially when it comes to irritable bowel syndrome, which occurs due to stress and nervous tension.

Therefore, you should always have anti-diarrhea tablets on hand that can neutralize the symptoms of diarrhea in the shortest possible time. One such drug is Imodium. It slows down intestinal motility, reducing the urge to defecate. We will discuss further how to use Imodium anti-diarrhea tablets and what you need to know.

Pharmacokinetics

The main active ingredient of the drug is loperamide, which, after entering the gastrointestinal tract, is completely absorbed, penetrating into the intestines. This substance is not able to be absorbed into the blood, so it acts locally, bypassing the general bloodstream. This is one of its main advantages, thanks to which the therapeutic effect occurs as quickly as possible.

The drug molecules act on opioid receptors, suppressing the synthesis of prostaglandins and acetylcholines.

This in turn reduces the sensitivity of the mucous membrane to the irritant, which helps reduce the manifestations of diarrhea. Slow peristalsis provokes a decrease in the speed of movement of masses through the intestines, due to which the urge to defecate disappears immediately after taking the pill.

Loperamide has a selective effect, that is, it affects exclusively the intestinal mucosa, without reducing concentration and speed of psychomotor reactions. Its effectiveness can also be described by the following therapeutic manifestations:

• regulates the production of mucus by the cells of the intestinal mucosa;
• increased tone of the rectum and sphincter, which dulls diarrhea, reducing urge;
• normalization of the absorption of nutrients in the intestines, which avoids dehydration and disturbances in water-salt balance;
• decreased spasm of smooth muscles, which helps eliminate unpleasant pain in the abdomen;
• slowing down intestinal motility.

The complete elimination period is hours.

Does it help with diarrhea?

The drug reduces intestinal motility, helping to reduce the urge to defecate.

Release form and composition

The drug is produced in the form of lozenges, as well as in the form of gelatin-coated capsules.

Each tablet and capsule contains 2 mg of the main component loperamide hydrochloride, as well as auxiliary components such as natural flavor (mint), gelatin, aspartate. The tablets are packaged in plastic blisters of 10 or 20 pcs.

Capsules are packaged in plastic blisters of 10 pieces. One package contains 1 or 2 blisters.

Dosage and application regimen

The tablets are intended for resorption in the oral cavity. To do this, it is placed under the tongue or behind the cheek, where it slowly dissolves. In the presence of acute diarrhea, use 1 tablet every 3-4 hours. As maintenance therapy, the drug can be used twice a day, morning and evening. If diarrhea has not decreased on the second day, a decision is made to discontinue this medication and replace it with another.

Capsules are taken orally with a small amount of water. For acute diarrhea, it is recommended to take 1 capsule three times a day. If there is no bowel movement for more than three days, the medicine should be discontinued.

In the presence of chronic diarrhea caused by systemic diseases, you should take Imodium 1 tablet per day or 1 capsule. For chronic forms of diarrhea, it is recommended to use capsules, since they dissolve directly in the intestines, which provides a prolonged antidiarrheal effect. The dosage should be adjusted depending on the improvement of the patient's condition. Imodium is suitable for both long-term and one-time use.

The maximum daily dose is mg, which is equal to 8 tablets. Their intake is divided into equal periods of time, which ensures maximum effect.

Indications for use

Imodium is prescribed in the presence of diarrhea of ​​various etiologies. For bacterial diarrhea, it acts as an adjuvant in complex therapy. If diarrhea is a consequence of systemic diseases and disturbances of the intestinal microflora, it can be used as the main medicine for diarrhea.

If there is an intestinal disorder caused by pathogenic microflora, treatment is supplemented with medications such as:

1. Antibiotics (Nifuroxazide, Ceftriaxone, Cefazolin) - help destroy bacteria not only in the intestines, but throughout the body.
2. Enterosorbents (Sorbex, Laktofiltrum, Polysorb) - help reduce the concentration of toxic substances produced by bacteria by gluing and neutralizing them.
3. Probiotics (Linex, Bifiform, Acipol) - replenish the deficiency of benign bacteria in the intestines by seeding the mucous membrane.

If diarrhea has other causes (stress, diseases of the stomach and intestines), the following may be included in the course of treatment:

• enzymes;
• diuretics and choleretic drugs;
• drugs that normalize pH;
• antidepressants.

Contraindications

Considering the fact that the drug has a local effect and practically does not enter the general bloodstream, there are still some contraindications for use that should be taken into account when choosing remedies for diarrhea. These include:

• the presence of ulcerative colitis, accompanied by profuse and prolonged diarrhea;
• severe constipation (no bowel movements for more than 4 days);
• bloating and increased gas formation;
• intestinal pathologies, in which it is extremely dangerous to reduce its motility;
• in the presence of blood and pus in the stool;
• acute dysentery, which is characterized by vomiting and high fever;
• intestinal obstruction not associated with diarrhea;
• diverticulosis;
• first trimester of pregnancy;
• children under 5 years of age, due to the presence of a high dosage of loperamide.

Nuances of use for special categories of patients

To date, it is not reliably known how Imodium affects the intrauterine development of the fetus. There are no facts that would confirm its detrimental effect on the development of a child. However, you should not self-medicate during pregnancy. It is strictly forbidden to use the drug in the first trimester of pregnancy, when all the vital organs and systems of the child are formed. In the case when the doctor assesses the current situation and notes that the expected benefit to the mother is several times greater than the possible harm to the fetus, the drug is prescribed using minimal dosages. Treatment should begin with lozenges, using no more than half at a time.

Long-term use of this medication during lactation can provoke the development of persistent constipation in the child, as well as impaired intestinal motility. Accordingly, Imodium is not used during lactation.

Children under 5 years of age are strictly prohibited from using this medicine. After 5 years, diarrhea therapy is carried out taking into account the individual characteristics of the child, paying attention to weight. The calculation is carried out as follows: for every 20 kg of weight, 1 tablet. The frequency of doses is 1-2 times a day. For children, it is recommended to use lozenges, as they are easier to dose. After resorption, you do not need to give it a drink, at least for a few minutes. The course of treatment is 1-2 days. If there is no effectiveness, the medicine is replaced with an analogue.

In elderly patients, intestinal motility naturally slows down due to decreased secretion. This fact should be taken into account, since there are often cases when, after taking Imodium tablets, patients complained of persistent constipation and difficulty in normalizing stool.

special instructions

It has been proven that the drug has little effect on the liver and kidneys. However, for patients who have pathologies in the functioning of these organs, it is important that constant monitoring is carried out.

Imodium

Description current as of 01/24/2015

• Latin name: Imodium
• ATX code: A07DA03
• Active ingredient: Loperamide
• Manufacturer: Janssen-Cilag (France), Johnson & Johnson (Russia), Gedeon Richter (Hungary)

Compound

The composition of the drug includes loperamide hydrochloride as an active substance. Additional capsule components: lactose, talc, corn starch, magnesium stearate. The capsule shell contains yellow iron oxide, titanium dioxide, erythrosine, black iron oxide, indigo carmine, gelatin.

Release form

The medicine is available in capsules and lozenges.

pharmachologic effect

Pharmacodynamics and pharmacokinetics

The medicine acts as an antidiarrheal agent. Its active substance is a synthetic selective inhibitor of opioid receptors. It affects the cells of the intestinal walls. The release of acetylcholine and prostaglandins in the gastrointestinal tract is blocked by affecting the functions of cholinergic and adrenergic neurons.

After taking Imodium, an increase in the tone of the anal sphincter and rectum is observed. Feces are better retained, and the urge to defecate becomes less frequent. Intestinal motility decreases. The contents travel through the gastrointestinal tract longer.

The drug normalizes the amount of mucus in the intestinal lumen by reducing its secretion. It also improves the absorption of fluids and electrolytes from the gastrointestinal tract, reducing the likelihood of dehydration and problems with electrolyte balance, which often appear with diarrhea. The active substance reduces pain that can be caused by spasm of the smooth muscles of the intestinal wall.

The medicine is easily absorbed from the gastrointestinal tract. It works quickly. It is broken down in the liver and excreted mainly with bile and feces. Half-life is 9-14 hours. The systemic impact is negligible.

Indications for use of Imodium

Indications for the use of Imodium: the need for symptomatic treatment of acute and chronic diarrhea. Recommended for use for traveler's diarrhea. In this case, the drug is used for two days. But whatever the indications for the use of Imodium, the use of this drug should be discontinued if bloody discharge appears in the stool until the cause is determined.

Contraindications

This drug should not be used if you are hypersensitive to its components. In addition, the following contraindications are known:

Prescribe with caution for liver dysfunction. Before using the drug, contraindications must be excluded.

Side effects

Adverse reactions may depend on the nature of the disease:

In addition, the following side effects are known:

The medicine may cause drowsiness, so when using it, it is not advisable to perform work that involves the use of dangerous mechanisms.

During clinical trials, the most commonly reported adverse reactions that are characteristic of diarrhea syndrome are: abdominal pain, nausea, dry mouth, drowsiness, constipation, discomfort and excessive fatigue, vomiting, dizziness, flatulence. Thus, it is difficult to distinguish these manifestations from side effects.

Instructions for use of Imodium (Method and dosage)

The drug should be used only after consultation with a doctor. Only a specialist knows how to use Imodium, what it will help with in each specific case and how long it should be used. In the case of acute and chronic diarrhea, 2 capsules are usually used at the beginning of the course. Instructions for the use of Imodium for children over 6 years old indicate that in this case, as a rule, they are given one capsule per day.

For the purpose of maintenance therapy, the dosage is adjusted so that bowel movements occur 1-2 times a day. As a rule, it ranges from 1 to 6 capsules for adults. The maximum dosage is no more than 8 capsules. Children over 6 years old are given no more than 3 capsules.

For those taking Imodium tablets, the instructions for use advise that they should be placed on the tongue and allowed to dissolve for a few seconds, after which they should be swallowed without liquid.

In case of acute diarrhea, the initial dosage is 2 tablets for adults and 1 tablet for children over 6 years of age. If the drug works successfully, it is continued to be taken one tablet after each bowel movement in case of loose stools.

The initial daily dose for chronic diarrhea is 2 tablets for adults and 1 tablet for children. Then the dosage is adjusted individually so that the frequency of stool is 1-2 times a day. Every day an adult patient can take from 1 to 6 tablets. The maximum dose should not exceed 8 tablets. For children, dosages are calculated based on weight (3 tablets per 20 kg, but not more than 8 tablets).

If, in case of acute diarrhea, the effect of the drug is not observed for two days after use, its use should be stopped immediately and another medicine should be selected. When the patient begins to have normal stools or does not have them for 12 hours or more, the drug is also discontinued.

Overdose

In case of an overdose, symptoms of central nervous system depression may appear: stupor, drowsiness, loss of coordination, miosis, muscle hypertonicity, etc. In addition, urinary retention and a set of symptoms reminiscent of intestinal obstruction are possible.

Children when taking the drug are more sensitive to the effects on the central nervous system.

Naloxone can be used as an antidote. It may need to be reapplied as Imodium lasts longer. To identify possible symptoms of overdose, the patient should be observed for two days. Treatment is symptomatic. Gastric lavage and the use of activated carbon are possible.

Interaction

Combination with P-glycoprotein blockers can lead to an increase in plasma loperamide levels by at least 2-3 times.

Terms of sale

Available without a prescription.

Storage conditions

The medicine should be stored in a dry place at room temperature.

Best before date

5 years. This product cannot be used after the expiration date, which is indicated on the original packaging.

Imodium analogs

In the pharmacy chain you can find the following analogues of Imodium:

All medications have their own application characteristics. Imodium analogues are not recommended for use without consulting a doctor. If the drug turns out to be ineffective, you need to consult a specialist before purchasing another replacement product.

The price of analogues, as a rule, is noticeably lower than the cost of Imodium.

Imodium for children

Only a specialist knows what the tablets will help with in each specific case and how to take them for children under 6 years of age, so they should be given under strict medical supervision.

Imodium for children over 6 years of age should be given in lower dosages than for adults. They are determined by a specialist individually.

It is not advisable to give Imodium to children under 6 years of age in capsule form.

Imodium during pregnancy and lactation

Imodium should be used with caution during pregnancy. It does not have a teratogenic, embryotoxic or mutagenic effect on the fetus. During pregnancy, it may be prescribed if the expected benefit to the mother outweighs the possible risk to the child.

Cannot be used during breastfeeding. If admission is necessary, discontinuation of breastfeeding should be considered.

The drug Imodium's indications for use are laconic: caused by intestinal motility disorders and external irritants of a non-bacterial nature. But despite the apparent ease of use, this medicine cannot be used thoughtlessly.

What do Imodium tablets actually help with?

Stomach upset and diarrhea can occur for a variety of reasons. Imodium will effectively cope with diarrhea of ​​any origin, but this will not always benefit the patient. Let's find out why.

The main active ingredient in this drug is loperamide. It selectively acts on receptors of the intestinal mucosa, blocking some of them. As a result, motor functions weaken, the sphincter closes more tightly, the movement of feces slows down and mucus production stops. The effect has been achieved - the contents of the intestines no longer ask to be released. But diarrhea didn’t just start out of nowhere!

If the body is in a hurry to empty itself, it means it needs to get rid of some substances. The use of Imodium is justified in cases where diarrhea does not stop for a long time and the body continues to spew out water and waste products. In this case, diarrhea must be stopped urgently to avoid dehydration and other dangerous phenomena. Imodium will cope with this task better than any other product. If the situation is not so critical, it is better to choose an antidiarrheal drug from a number of enterosorbents or microbiotic drugs.

Imodium has the following indications for use:

• allergic diarrhea;
• diarrhea of ​​a neuro-emotional nature;
• diarrhea caused by certain medications and radiation therapy;
• upset stomach due to changes in climate, diet, water;
• ileostomy causing fecal incontinence.

How to use Imodium

For adults, the drug is indicated for use 2-3 times a day, 2 mg, that is, one capsule at a time. The maximum daily dose is 16 mg. In emergency cases, the first dose may include 4 mg of Imodium. Children are recommended to take 1-2 capsules per day, the maximum possible amount of the drug is 8 mg per day. Children under 6 years of age should only use Imodium under medical supervision. The dose should be selected strictly individually.

The drug begins to act within an hour after administration, the maximum effect is achieved after 2-3 hours. After 4 hours, Imodium is inhibited by the liver and kidneys and leaves the body in the urine. If you have used other antidiarrheals, the effect of the medicine may be completely unpredictable - prolonged or short-term. It is advisable to avoid such cases.

Contraindications to the use of Imodium

This medicine has quite a lot of contraindications. First of all, these include the following factors:

Also, the drug is not used in the treatment of children under 5 years of age and in the first trimester of pregnancy. Imodium can be used only by doctor's prescription for people with impaired kidney and liver function.

The drug Imodium-plus has no different indications for use and contraindications; the drug contains a component that reduces flatulence and relieves cramps. The only difference between Imodium and Imodium-plus is that the latter is somewhat easier to tolerate and eliminates the symptoms associated with diarrhea.

Imodium is a medicine designed to combat the symptoms of diarrhea. The most common form of release is lyophilized lozenges, chewable tablets (Imodium plus), capsules.

Lyophilization is the drying of substances by rapid freezing and placing in a vacuum chamber. This method is used to increase the shelf life of substances, in this case it is loperamide hydrochloride, which is the main active ingredient of Imodium.

In this article we will look at why doctors prescribe the drug Imodium, including instructions for use, analogues and prices for this drug in pharmacies. If you have already used Imodium, leave your feedback in the comments.

Composition and release form

Pharmacological action: antidiarrheal agent.

• Lingual tablets are white or almost white in color and round in shape. 1 tablet contains 2 mg of loperamide hydrochloride and excipients (aspartame, sodium bicarbonate, mannitol, mint flavor and gelatin). Imodium tablets are packaged in blisters of 6 or 10 pieces, in a cardboard pack there are 1 or 2 blisters.
• One capsule of Imodium contains 2 mg of loperamide hydrochloride and auxiliary components (talc, corn starch, magnesium stearate and lactose). The capsule shell contains yellow iron oxide, black iron oxide, sodium indigotin disulfonate, titanium dioxide, gelatin and sodium erythrosine. Imodium capsules are packaged in 6 or 20 pieces in blisters, 1 blister in a cardboard pack.

As you can see, the drug is available in two dosage forms - film-coated capsules and lingual tablets.

What is Imodium used for?

Imodium is used for non-infectious diarrhea of ​​various forms and origins:

• in cases of acute and chronic diarrhea;
• in cases of drug-induced, emotional, allergic and radiation diarrhea;
• due to changes in diet and type of food;
• in cases of metabolic disorders and disturbances of the absorption mechanism;
• for correction of stool in patients with ileostomy;
• as an additional remedy for infectious diarrhea.

pharmachologic effect

Imodium - the antidiarrheal effect of the drug is due to the selective effect of the active substance on the cells of the intestinal walls, increasing the tone of its muscles, blocking acetylcholine and prostaglandin receptors, as well as reducing its secretory activity. In addition, Imodium slows down the movement of feces and reduces pain in the abdominal area by eliminating spasms of smooth muscles.

Imodium is quickly absorbed and has a therapeutic effect within half an hour after its use. Its elimination occurs 18-28 hours after administration, with bile or feces. The drug is neutralized in the liver.

Instructions for use

Imodium capsules are taken orally half an hour before meals. Lozenges are placed on the tip of the tongue. Within a few seconds, the tablet dissolves and can be swallowed without drinking water.

• For adults with acute diarrhea, the first dose is 4 mg, then 2 mg after each act of defecation in case of loose stools. For chronic diarrhea, the first dose is 2 mg, the maintenance dose is selected so that the stool frequency is 1-2 times a day (2-12 mg/day). The maximum daily dose for adults is 16 mg.
• Children aged 4-8 years – 1 mg 3-4 times a day for 3 days; 9-12 years – 2 mg 4 times a day for 5 days.

Stop taking the drug when formed stool appears or if there is no urge to defecate for more than 12 hours.

Contraindications

Imodium should not be used in the following cases:

1. Acute ulcerative colitis;
2. Diverticulosis;
3. Intestinal obstruction (including in cases where suppression of peristalsis is not recommended);
4. First trimester of pregnancy and period of breastfeeding (lactation);
5. Pseudomembranous enterocolitis (diarrhea associated with antibiotics);
6. Acute dysentery and other gastrointestinal tract infections (caused, including Shigella spp., Salmonella spp., Campylobacter spp.);
7. Age up to 6 years;
8. Hypersensitivity to the components of the drug.

Imodium should be used with caution in patients with liver failure.

Side effects

The drug is usually well tolerated by patients, however, the following adverse reactions may develop:

1. Allergic reactions: pruritus, urticaria, erythema, Steven-Johnson syndrome, toxic epidermal necrolysis. If recommended doses were exceeded or there was increased individual sensitivity, patients developed anaphylactic shock.
2. From the gastrointestinal tract: dry mouth, intestinal obstruction, dyspepsia, lower abdominal pain, nausea, vomiting, flatulence, defecation disorders. Sometimes patients experience megacolon and toxic megacolon.
3. From the central nervous system: headache, dizziness, increased fatigue, disturbance of sleep and wakefulness.
4. Other side effects: urinary retention.

If any side effects occur, you should stop taking the drug and contact your doctor.

Overdose

An overdose of Imodium may cause central nervous system depression (impaired coordination, miosis, drowsiness, stupor, respiratory depression, muscle hypertonicity), urinary retention and a symptom complex characteristic of intestinal obstruction.

Treatment for overdose. If symptoms consistent with an Imodium overdose occur, naloxone can be used as an antidote. Due to the fact that the duration of action of Imodium is longer than that of naloxone, repeated administration of naloxone may be necessary.

In case of overdose, symptomatic therapy is also carried out. For timely detection of possible CNS depression, the patient must be under medical supervision for 48 hours.

Pregnancy and lactation

Contraindicated in the first trimester of pregnancy. In the second and third trimesters of pregnancy, loperamide can be prescribed in cases where the expected benefit of therapy for the mother outweighs the potential risk to the fetus.

Because small amounts of loperamide are found in breast milk, use during breastfeeding is not recommended.

Analogs

In the pharmacy chain you can find the following cheap analogues of Imodium:

1. Lopedium;
2. Loperamide;
3. Loperamide Grindeks;
4. Loperamide Hydrochloride;
5. Stoperan;
6. Imodium Lingual;
7. Loperamide-Health.

Attention: the use of analogues must be agreed with the attending physician.

Prices

The average price of Imodium in pharmacies (Moscow) is 180 rubles.

Storage conditions

Dry place without access to light at room temperature. Shelf life – no more than 5 years.