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Latin name: Ringer's solution
ATX code: B05BB01
Active substance: Calcium chloride,
potassium chloride and sodium chloride
Manufacturer: Kraspharma, Russia
Dispensing from the pharmacy: On prescription
Storage conditions: t from 15 to 25 C
Best before date: 2 years.
Ringer's solution is a drug that is used to restore electrolyte balance in cases of shock, as well as in case of large blood loss.
The drug can also be used for inhalation to eliminate signs of rhinitis.
The solution (1000 ml) contains sodium chloride, calcium chloride and potassium chloride, their mass fraction in the medicine is 8.6 g; 0.33 g; 0.3 g respectively. Ringer's solution also contains:
The colorless injection solution is dispensed in polyethylene bottles of 250 ml and 500 ml; there are 10 bottles inside the pack. The drug is also sold in glass bottles of 200 ml and 400 ml, the packaging can hold 1, 15 or 28 fl.
The INN of the drug does not match trade name. Ringer's solution helps replenish excessive fluid loss, participates in the detoxification process, and helps normalize electrolyte balance. Quite quickly, but briefly, it increases the volume of blood circulating in the body due to its rapid release into the extravascular space.
Ringer's solution is capable of restoring blood volume for about 40 minutes; this must be taken into account during emergency medical care.
The detoxification effect of drugs manifests itself due to the rapid dilution and increase in the volume of circulating blood, as a result of which the concentration of toxic substances in the blood decreases.
Price: from 19 to 1038 rubles.
Ringer's solution is indicated for administration exclusively intravenously (a dropper is placed or infused as a stream). The medicine is dripped at a rate of 60-80 drops. in 1 min.
The selection of daily dosage for children and adults is carried out individually. Ringer solution is used to set up infusions after consultation with a doctor.
Dose for children – 5-10 ml per 1 kg of weight. The medicine should be administered to the child at a rate not exceeding 60 drops. in 1 min. At severe cases it is possible to increase the daily dose to 30 ml per 1 kg of weight.
For an adult, the dose is calculated as follows - 20 ml per 1 kg of body weight. The maximum dosage should not be more than 50 ml per 1 kg.
Duration therapeutic therapy depends on the nature of the disease, usually 3-5 days. Is it possible to carry out further treatment, you should check with your doctor.
Included complex therapy for rhinitis, it is recommended to carry out inhalation procedures with a nebulizer; for one application you will need to take 5 ml of medicine. It is recommended to carry out 2 inhalations per day. The duration of treatment depends on the observed therapeutic effect.
During pregnancy and during breastfeeding The drug should not be used, since experience in its use is limited.
The use of Ringer solution for infusion is not allowed for:
When carrying out long-term treatment with these drugs, the level of electrolytes in the blood should be monitored, as well as acid-base balance blood.
Do not use Ringer's solution after the expiration date, if the integrity of the packaging is damaged, if the injection solution becomes cloudy or if a precipitate appears or changes color.
Cross-drug interactions
Possible Na retention with combined use:
If you drink cardiac glycosides at the same time, their toxic effects may increase.
If you take medications containing ACE inhibitors, diuretics, or potassium-based medications, signs of hyperkalemia may appear.
Side effects
The development of adverse symptoms is most often associated with an increase in prescribed doses and a change in the treatment regimen. Signs of allergies may appear, a decrease in plasma potassium levels, and the development of overhydration.
Overdose
There may be an increase in the frequency or severity of side symptoms. It is recommended to discontinue the medication and adjust the treatment regimen.
Biosynthesis, Russia
Price from 20 to 45 rub.
Acesol, one of the analogues of Ringer's solution, is a plasma-substituting drug that exhibits antiplatelet and diuretic effects and helps eliminate intoxication. The main components are sodium and potassium chloride, sodium acetate. Produced in the form of an injection solution.
Pros:
Minuses:
Rehydration and detoxification drug for parenteral use
Solution for infusion transparent, colorless.
Excipients: water for injection.
Theoretical osmolarity 309 mOsm/L
200 ml - glass bottles (1) - cardboard packs.
200 ml - glass bottles (15) - cardboard boxes.
200 ml - glass bottles (28) - cardboard boxes.
400 ml - glass bottles (1) - cardboard packs.
400 ml - glass bottles (15) - cardboard boxes.
A rehydrating agent, it has a detoxifying effect, restores the water and electrolyte composition of the blood. When used as a means of replenishing the volume of circulating blood, due to the rapid exit from the bloodstream into the extravasal space, the effect lasts for only 30-40 minutes (and therefore the solution is suitable only for short-term replenishment of the volume of circulating blood).
Thermal injury acute blood loss; dehydration; intestinal fistula; spicy intestinal infections(severe course, inability to take oral rehydrating agents); therapeutic plasmapheresis; correction of water and salt balance for acute diffuse peritonitis and intestinal obstruction.
Hypersensitivity, hypernatremia, hyperchloremia, acidosis, severe chronic failure, cerebral edema, pulmonary edema, chronic renal failure, concomitant therapy with glucocorticosteroids.
IV drip, at a speed of 60-80 drops/min, or stream. Daily dose for adults - 5-20 ml/kg, if necessary, can be increased to 30-50 ml/kg. The daily dose for children is 5-10 ml/kg, the rate of administration is 30-60 drops/min, in case of shock, 20-30 ml/kg is initially administered. The course of treatment is 3-5 days. During therapeutic plasmapheresis, it is administered in a volume 2 times greater than the volume removed (1.2-2.4 l), in case of severe hypovolemia - in combination with colloid solutions. The maximum volume of injected solution is 3 l/day.
Overhydration, hypokalemia, allergic reactions.
In case of overdose, an imbalance of water and electrolytes may occur (hypervolemia, hypernatremia, hyperkalemia, hypercalcemia, hyperchloremia) and acid-base balance. In case of overdose, in most cases, it is enough to interrupt the administration.
In the case of rapid administration of a large volume, it is necessary to monitor the acid-base status and electrolyte concentration. A change in blood pH leads to a redistribution of K+ (a decrease in pH leads to an increase in the content of K+ ions in the blood serum). Freezing the drug, provided the container remains sealed, is not a contraindication to the use of the drug. If the contents of the container become cloudy, do not use. When combining with other drugs, it is necessary to visually monitor compatibility.
The ability to influence the reaction rate when driving a vehicle or working with other mechanisms. Information is absent.
Waiting for the birth of a child is a wonderful time, which for a number of reasons can be darkened feeling unwell and health problems of the expectant mother. Infusions are often used to correct conditions that are dangerous for a pregnant woman and her child. Below we will talk about which droppers and in what cases are most often prescribed to pregnant women.
Unpleasant, but seemingly harmless, the notorious early toxicosis of pregnant women is not so harmless. Moderate to severe severity of this condition is characterized by nausea and vomiting 5-20 times a day. Consequence frequent vomiting is dehydration, metabolic disorders, decreased blood pressure, constipation. A pregnant woman can lose up to 10 percent of her original body weight. The lack of treatment for pronounced early toxicosis leads to a lack of nutrients supplied to the embryo, which is especially bad in the early stages of pregnancy, when the organs of the unborn child are formed.
It is worth noting that abroad the phrase “hypertonicity of the uterus” means a rare and dangerous complication in childbirth. There is nothing terrible about uterine hypertonicity in the meaning that domestic gynecologists put into this diagnosis. Uterus - muscular organ, which by definition must be in good shape, otherwise pregnancy is impossible. Pressure from an abdominal ultrasound sensor and active fetal movement can provoke an increase in uterine tone. There is no need to correct the tone detected on ultrasound or expressed in slight stretching of the abdomen.
Obstetricians in the post-Soviet space have a different view of uterine tone. They often offer pregnancy-preserving therapy, including infusions.
Detachment of the ovum, bleeding, problems with blood flow that began earlier due date contractions - all this can lead to very disastrous consequences and requires medical intervention.
Preeclampsia - dangerous to life and health expectant mother and fetal condition that occurs in the second half of pregnancy. It is observed in every sixth pregnant woman. Typical symptoms gestosis is swelling, including hidden edema, manifested as severe weight gain, high blood pressure and the appearance of protein in the urine.
Pharmachologic effect:
Indications for infusion:
Glucose in the form of a dropper is safe in early pregnancy. Glucose infusions are often prescribed to expectant mothers as part of therapy aimed at getting rid of early toxicosis.
Contraindications:
Pharmachologic effect:
Indications for infusion:
Prescription during pregnancy:
Sodium chloride droppers during pregnancy in obstetrics and gynecology are used to alleviate the condition of a woman with moderate and severe toxicosis, to reduce blood pressure during childbirth, during anesthesia or when gestosis occurs, to combat swelling.
Contraindications:
Pharmachologic effect:
Indications for infusion:
Use during pregnancy:
Ringer's droppers are prescribed for severe early toxicosis of pregnant women. The need to use the drug for pregnant women is determined by the doctor after assessing the risk/benefit ratio.
Contraindications:
Pharmachologic effect:
Indications for infusion:
Use during pregnancy:
Contraindications:
Pharmachologic effect:
Indications for infusion:
Papaverine is popular among gynecologists in the CIS countries. It is often prescribed for removal increased tone uterus. Papaverine is not used in obstetrics in Europe and America.
At the moment, there is no convincing evidence of the effectiveness of the drug.
Contraindications:
Pharmachologic effect:
Indications for infusion:
Use during pregnancy:
Ginipral in a dropper during pregnancy can be prescribed as early as the second trimester of pregnancy. The drug suppresses contractions, helps relax the uterine muscles and prolongs the pregnancy period.
Contraindications:
Pharmachologic effect:
Indications for infusion:
Use during pregnancy:
Tranexam is prescribed for bleeding during pregnancy and chorionic detachment. Indications for infusion are also bleeding in postpartum period, manual separation of membranes.
Contraindications:
Pharmachologic effect:
Indications for infusion:
The main reason for prescribing the drug to pregnant women is the correction of feto-placental insufficiency (FPI) - circulatory disorders in the mother-placenta-fetus system. With FPN, the fetus receives less nutrients and oxygen, which is fraught with deviations in its development or even death. To treat FPN, the doctor may also prescribe Pentoxifylline or Trental during pregnancy; droppers with these drugs are equally effective, since active substance Both medications are the same.
Pentoxifylline infusions can be administered intravenously and intra-arterially.
A study of Pentoxifylline on animals revealed a negative effect of the drug on offspring. No human trials have been conducted, but pregnancy is still included in the list of contraindications. Prescribing Pentoxifylline droppers for blood flow during pregnancy is strictly prohibited in the first trimester, when fetal organs are developing. For more later It is appropriate to use a medicine in cases where the expected benefit is higher than the possible harm.
Contraindications:
Pharmachologic effect:
Indications for infusion:
Use during pregnancy:
Eufillin - powerful tool, prescribed to pregnant women primarily for the purpose of getting rid of pathological edema. A study of the drug on animals revealed a negative effect on the fetus, so it is better to resort to Eufillin droppers for edema during pregnancy only in extreme cases. Breastfeeding is also not recommended during treatment with this drug.
Contraindications:
Actovegin is a drug produced from the blood of calves. According to the manufacturer, it is an angioprotector and antioxidant, has wide range use, but there is no convincing evidence of the effectiveness of the product. The drug is used in the CIS countries. Banned in the USA.
Pharmachologic effect:
Indications for infusion:
Use during pregnancy:
Actovegin during pregnancy is prescribed to women with a history of miscarriages as pregnancy maintenance therapy, pregnant women, sick diabetes mellitus, if there is a threat of miscarriage, oxygen starvation in the fetus, low fetal body weight.
Contraindications:
Pharmachologic effect:
Indications for infusion:
Use during pregnancy:
Piracetam is able to penetrate the blood-placental barrier. Studies have not been conducted to understand the effects of Piracetam on the fetus, so the drug is prescribed to pregnant women only in extreme cases. During experiments on animals, negative impact The drug was not found to affect pregnancy and offspring.
The effectiveness of the drug is questionable.
Contraindications:
Pharmachologic effect:
Indications for infusion:
Use during pregnancy:
It is undesirable to use the drug in the second and third trimesters and is completely prohibited for use in the first trimester of pregnancy.
Contraindications:
Pharmachologic effect:
Indications for infusion:
Use during pregnancy:
Contraindications:
An IV during pregnancy is “heavy artillery” that can even save the lives of a pregnant woman and a child in her womb.
Self-medication is unacceptable for expectant mothers, and the prescription of IVs during pregnancy is no exception. What drugs can be used and which ones should be avoided? possible risks, dosage and duration of treatment - all this must be determined by the doctor.
Photo of the drug
Latin name:
Ringer's solutionATX code: B05BB01
Active substance: Calcium chloride + Potassium chloride + Sodium chloride
Manufacturer: Hemofarm (Serbia), Mosfarm, Biosintez, Sakhamedprom Gul, Medsintez Plant, Ozon Pharm, Eskom NPK, Kraspharma (Russia)
Description is valid on: 16.10.17
Ringer's solution is a medicine for restoring electrolytic balance. Promotes detoxification and replenishes fluid loss.
Sodium chloride solution is complex (Compound solution of sodium chloride).
Available in the form of a solution for infusion. It is a clear, colorless liquid. Packaged in 500 ml plastic bottles with built-in dropper holders.
Thermal injuries (frostbite, burns), shock of various etiologies, collapse, electrical injury, intestinal obstruction, acute peritonitis, poisoning of various origins, accompanied by persistent vomiting, intestinal fistula, therapeutic plasmapheresis, acute intestinal infections, characterized by severe diarrhea syndrome, which leads to dehydration of the body, intestinal fistula, alkalosis of metabolic etiology, accompanied by dehydration.
Cerebral edema, hypernatremia (high percentage of sodium in the blood plasma), pulmonary edema, hyperchloremia ( high concentration chlorine in the blood plasma), acidosis, renal failure, taking glucocorticosteroids, heart failure (stage of decompensation), individual intolerance to the drug.
The use of Ringer's solution during pregnancy and breastfeeding is possible only in in case of emergency, since there is no data on its safety in these conditions.
Intended exclusively for parenteral administration. It is administered intravenously by drip (the rate of administration of the solution varies from 60 to 80 drops per minute) or by stream ( emergency help on rehydration).
Average daily dosage medication for children is set at the rate of 5 - 10 ml per 1 kg of body weight. The rate of drug administration ranges from 30 to 60 drops per minute. In severe cases, the dose can be increased to 20 - 30 ml per 1 kg of weight.
The daily dose for adults is 5 – 20 ml per 1 kg of body weight. In emergency situations, the dosage is increased to 30–50 ml per 1 kg of weight.
The duration of therapy is determined by the attending physician individually(usually 3 to 5 days).
It is well tolerated; the side effects of the drug are mainly associated with its overdose. Ringer's solution may cause the following: side effects: allergy ( itchy skin, rashes, urticaria, etc.), overhydration, hypokalemia (decreased potassium concentration in the blood plasma).
For elimination side effects it is enough to reduce the dose of the solution. In case of allergic reaction it is necessary to immediately stop administering the drug and carry out desensitizing therapy.
In case of overdose, an imbalance of water and electrolytes (hypervolemia, hypernatremia, hyperkalemia, hypercalcemia, hyperchloremia) and acid-base balance may occur.
To eliminate the symptoms of an overdose, it is enough to interrupt the administration of the drug.
Analogs by ATX code: Addamel N, Acesol, Disol, Quintasol, Methusol.
Do not decide to change the drug on your own; consult your doctor.
Ringer's solution promotes detoxification, replenishes fluid loss, and also restores electrolytic balance in various states of shock and blood loss. The drug replenishes the BCC (circulating blood volume).
The agent very quickly enters the extravascular space, so it should be borne in mind that the latter effect is short-lived, lasting from 30 to 40 minutes. The detoxification effect of the drug is based on the effect of increasing the volume and thinning of the blood, which leads to a decrease in the concentration of toxic substances in it.
In the case of rapid administration of a large volume, it is necessary to monitor the acid-base status and electrolyte concentration. A change in blood pH leads to a redistribution of K+ (a decrease in pH leads to an increase in the content of K+ ions in the blood serum). Freezing the drug, provided the container remains sealed, is not a contraindication to the use of the drug. If the contents of the container become cloudy, do not use. When combining with other drugs, it is necessary to visually monitor compatibility.
During pregnancy, it is used in cases where the expected benefit to the mother outweighs the possible risk to the fetus. You should refrain from breastfeeding while using the drug due to the lack of relevant clinical data.
Daily dose for children: 5 – 10 ml/kg, rate of administration: 30 – 60 drops/min; for shock dehydration, 20 – 30 ml/kg is initially administered.
Information is absent.
Contraindicated in chronic renal failure.
Possible increase in sodium retention in the body with simultaneous administration the following medications: NSAIDs, androgens, anabolic hormones, estrogens, corticotropin, mineralocorticoids, vasodilators or ganglion blockers.
When taken with potassium-sparing diuretics, ACE inhibitors and potassium supplements increases the risk of developing hyperkalemia.
In combination with cardiac glycosides, the likelihood of their toxic effects increases.
Dispensed by prescription.
Store out of the reach of children at a temperature of +15... +25°C.
Shelf life – 3 years.
The price of Ringer's solution for 1 package starts from 347 rubles.
Attention!
The description posted on this page is a simplified version of the official version of the annotation for the drug. The information is provided for informational purposes only and does not constitute a guide for self-medication. Before using the medicine, you must consult a specialist and read the instructions approved by the manufacturer.
general characteristics:
Basic physicochemical characteristics : transparent, colorless and odorless liquid, salty taste. Theoretical osmolarity - 309 mOsmol/l;
Compound: 100 ml of solution contains sodium chloride 0.86 g, potassium chloride 0.03 g, calcium chloride 0.048 g;
excipients: water for injection.
Release form. Solution for infusion.
Pharmacotherapeutic group. Solutions for intravenous administration. Electrolytes.
ATS code B05B B01.
Pharmacological properties.
Pharmacodynamics. Ringer's solution normalizes the water-salt and acid-base balance and eliminates fluid deficiency in the human body, which develops during dehydration or due to the accumulation of extracellular fluid in areas of extensive burns and injuries, during organ operations abdominal cavity, with peritonitis. Ringer's solution improves the rheological properties of blood and tissue perfusion, increases the effectiveness of blood transfusion measures in case of massive blood loss and severe forms shock.
It also has a disinfecting effect due to a short-term increase in fluid volume, a decrease in the concentration of toxic products in the blood, and activation of diuresis.
Pharmacokinetics. It is quickly eliminated from the vascular system. The drug is retained in the vascular bed for 30-40 minutes and very quickly passes into the interstitial sector and intracellularly. After an hour, only about half of the injected solution remains in the vessels. Very quickly, salts and liquid begin to be excreted by the kidneys, increasing diuresis.
Indications for use. Iso- and hypotonic dehydration and metabolic acidosis as a result prolonged diarrhea, uncontrollable vomiting, with acute massive blood loss, with shock, extensive burns, with severe course postoperative period, poisonings of various etiologies.
Ringer's solution is also used externally to wash wounds.
Directions for use and doses. Ringer's solution is administered intravenously to adults at a rate of 4-10 mL/year in a volume of 50 ml to 3 liters. The drug is prescribed rectally for adults, 75-100 ml. Children under 6 years of age are prescribed at the rate of 5 ml/year in a volume of 50 ml to 500 ml. For children from 6 to 12 years of age, the dose of the drug is about half the dose for adults. For children over 12 years of age, the dose is the same as for adults.
Side effect. Using Ringer's solution in large quantities can lead to the development of chloride acidosis and overhydration.
Contraindications. Intravenous administration Ringer's solution is contraindicated in thrombophlebitis, conditions with increased coagulability blood, pronounced violation excretory function of the kidneys, with decompensated heart defects. The drug should not be administered in conditions where its administration can cause swelling of the brain and lungs, with hyperchloremia, hypernatremia, hyperhydration, metabolic alkalosis.
Overdose. With a significant overdose, phenomena of alkalosis and overhydration may be observed. In this case, the administration of the drug is stopped immediately. Symptomatic therapy is carried out.
Features of application. At long-term use, especially in large volumes, control the content of electrolytes in plasma, urine, and diuresis.
Interaction with others medicines . The drug cannot be mixed with phosphate and carbonate solutions. The drug can be used as a carrier solvent for other drugs.
Storage conditions. Store at a temperature of 0 to 25 ºС out of the reach of children.
Shelf life – 2 years.
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Date of publication: 03/30/17