Aspirin (acetylsalicylic acid) is one of the most famous remedies for fever. But the use of this medicine is more extensive - it even helps against thrombosis and other cardiovascular diseases.

Acetylsalicylic acid - description

Acetyl (acetylsalicylic) acid- a substance of the NSAID group, salicylic acid ester. The drug is included in the list of vitally important drugs, has long been known, and has been well studied. It has a number of positive effects on the body, the most important of which are antiplatelet, antipyretic, and analgesic. The drug was first patented by Bayer under the brand name Aspirin.

The acid was isolated in 1838 white willow bark- famous folk remedy from fever, headache. Initially it was used to treat rheumatism, then gout. Since 1904, the medicine has been sold in tablet form (initially it existed in powder form). Tablets of 0.1, 0.25, 0.5 g have round shape, in the middle - with a horizontal stripe.

Additional components:

• lemon acid;
• potato starch.

The drug is produced by almost all well-known pharmacological companies, for example, Dalkhimfarm, Tatkhimfarmpreparaty, Novasil.

Effect on the body

Given medicine It works as follows - it suppresses the synthesis of prostaglandins and inhibits the production of thromboxanes. The substance acts by inhibiting cyclooxygenase, and this enzyme takes part in the creation prostaglandins(inflammatory mediators) and thromboxanes. Acetyl salicylic acid influences the inflammatory process that occurs in tissues. Also medicine:

• reduces capillary permeability;
• reduces hyaluronidase activity;
• limits the formation of ATP, preventing energy from being provided to inflammatory phenomena.

When taken internally, the drug reduces fever - normalizes the temperature, which is due to its effect on the thermoregulation centers of the hypothalamus.

The acid also has an analgesic effect by reducing the production of bradycardin and influencing pain centers.

The most important ability of Aspirin is that it thins the blood - therefore the drug is widely used against the formation of blood clots.

All of these mechanisms of action provide the drug with analgesic, antipyretic, anti-inflammatory, antifever, and antirheumatic effects. Acid also reduces intracranial pressure and reduces headaches.

Indications for use

You can take the medicine for completely different pathologies belonging to different areas of medicine. The best known treatment is Aspirin for acute conditions accompanied by pain, fever, inflammation:

Acetyl acid also helps against pericarditis - inflammation in serosa hearts, with Dressler's syndrome(when pericarditis develops in combination with pneumonia, pleurisy). To thin the blood, Aspirin is indicated for many people over 55 who are at risk of heart attack or stroke. It should also be taken in long courses for ischemic heart disease, a stroke or a heart attack that has already occurred.

Other possible indications conditions for which Aspirin should be given:

• prevention of thromboembolism;
• heart defects;
• atrial fibrillation;
• acute thrombophlebitis;
• pulmonary infarction;
• TELA.

Using small doses of the drug, tolerance to NSAIDs is formed in the presence of the “aspirin triad” (nasal polyposis, bronchial asthma, allergy to acetyl acid).

Instructions for use

According to the instructions, acetyl acid should be taken orally, at the very beginning of a meal, or at the end of a meal. This will help prevent common side effects - the appearance of erosions, irritations on the wall of the stomach and small intestine.

Experts advise drinking Aspirin with milk or alkaline mineral water without gas - this will reduce the irritating effect of acid on the digestive system.

The dosage varies, depending on age and type of disease. Usually enough to drink 0.5 g 2-4 times/day(quantity indicated is for adults). Course duration is up to 12 days, more often - 3-5 days.

Features of therapy in in some cases are:

1. To prevent problems of the heart and blood vessels, dangerous thrombosis. Take half a tablet in the morning (once a day). The course is up to 2 months without a break. At the same time, blood clotting and platelet count tests are done every 2 weeks.
2. For rheumatism. Take Aspirin 5-8 g/day for adults, children 100 mg per kg of weight/day. Specified dose divided into 5 steps. After a week of such pulse therapy, the dosage is reduced to individually, total duration - 6 weeks. Cancellation is carried out gradually.
3. For headaches. An adult can take 2 tablets, a child - 10 mg/kg body weight per dose.
4. Children from 5 years old are usually given 0.25 g of Aspirin per dose, from 2 years old - 0.1 g, from 1 year old - 0.05 g.

The drug is widely used in cosmetology. For example, there is a recipe for a face mask against acne. You need to grind 6 tablets, add lemon juice or honey until it becomes a paste. Apply only to inflamed areas of the skin, leave for 15 minutes, rinse.

Side effects and prohibitions

It is strictly forbidden to give acetyl acid to children if they develop viral infection. In this case, the risk of Reye's syndrome is high, since the drug acts on the structures of the liver and brain that are attacked by the virus. There are other contraindications to therapy:

In many cases, long-term therapy causes a number of side effects. These are nosebleeds, uterine, intestinal, diarrhea, dyspepsia, nausea, vomiting, poor appetite, weakness, dizziness. Short-term visual impairment is possible. The amount of hemoglobin and platelets in the blood may change. With a tendency to kidney pathologies, some people develop renal failure. Allergic reactions include bronchospasm, asthma, rash, and anaphylaxis.

Acetylsalicylic acid, tablets: instructions for use

Compound

pharmachologic effect

Pharmacokinetics

Indications for use

Fever in infectious and inflammatory diseases;

Pain syndrome of weak and medium intensity of various origins.

Contraindications

Directions for use and doses

Side effect

When estimating frequency adverse reactions The following gradation is used:

Very common: ≥1/10;

Very rarely:

Not known: frequency cannot be estimated due to lack of data.

From the outside digestive system: often - nausea, vomiting, anorexia, epigastric pain, diarrhea; rarely - the occurrence of erosive and ulcerative lesions, bleeding from the gastrointestinal tract, impaired liver function.

From the side of the central nervous system: at long-term use possible dizziness, headache, reversible visual impairment, tinnitus, aseptic meningitis.

From the hematopoietic system: rarely - thrombocytopenia, anemia.

From the blood coagulation system: rarely - hemorrhagic syndrome, prolongation of bleeding time.

From the urinary system: rarely - renal dysfunction; with long-term use - acute renal failure, nephrotic syndrome. Allergic reactions: infrequently - skin rash; rarely - Quincke's edema, bronchospasm, "aspirin triad" (a combination of bronchial asthma, recurrent polyposis of the nose and paranasal sinuses and intolerance to acetylsalicylic acid and pyrazolone drugs).

Others: very rarely - Reye's syndrome; with long-term use - increased symptoms of chronic heart failure.

Overdose

Overdose is possible with a single administration of excessively high doses of the drug or with long-term use.

Symptoms: salicylic syndrome (nausea, vomiting, tinnitus, general malaise, fever). More severe poisoning - stupor, convulsions and coma, non-cardiogenic pulmonary edema, severe dehydration, impairment of CBS (initially - respiratory alkalosis, then metabolic acidosis), kidney failure and shock.

Interaction with other drugs

When used simultaneously with acetylsalicylic acid:

Antacids containing magnesium and/or aluminum hydroxide slow down and reduce the absorption of acetylsalicylic acid;

Blockers calcium channels, drugs that limit the intake of calcium or increase the excretion of calcium from the body - the risk of bleeding increases;

The effect of heparin is enhanced and indirect anticoagulants, methotrexate, phenytoin, valproic acid;

Antidiabetic agents - lowering blood sugar levels;

GCS - increases the risk of ulcerogenic effects and gastrointestinal bleeding;

The effectiveness of diuretics (spirolactone, furosemide) decreases;

Other NSAIDs - increases the risk of developing side effects;

Acetylsalicylic acid may reduce plasma concentrations of indomethacin, iroxicam;

The effectiveness of uricosuric drugs decreases;

Griseofulvin - possible disruption of absorption of acetylsalicylic acid;

The concentrations of digosin, barbiturates and lithium salts in the blood plasma increase;

Reduced effectiveness of captopril and enalapril (when using acetylsalicylic acid in high doses);

Caffeine - increases the rate of absorption, plasma concentration and bioavailability of acetylsalicylic acid, the risk of adverse reactions;

Platelet aggregation inhibitors - increased risk bleeding;

Alcohol - increased risk of developing gastrointestinal ulcers and bleeding;

Inhibitors recapture serotonin - increases the risk of developing gastrointestinal bleeding.

Precautionary measures

5-7 days before surgical intervention it is necessary to cancel the dose (to reduce bleeding during the operation and in postoperative period). The irritant effect on the gastrointestinal tract is reduced when administered after meals. During long-term therapy, it is recommended to regularly perform blood tests and examine stool for occult blood. Not recommended for relief of febrile syndrome in children.

ASA, even in small doses, reduces excretion uric acid from the body, which can cause the development acute attack gout in predisposed patients. During the treatment period, you should refrain from taking ethanol.

Use during pregnancy and lactation. Use is contraindicated in the 1st and 3rd trimester of pregnancy and during lactation.

Has a teratogenic effect; when used in the first trimester leads to the development of clefting upper sky; in the third trimester causes inhibition labor activity(inhibition of Pg synthesis), premature closure ductus arteriosus in the fetus, pulmonary vascular hyperplasia and hypertension in the “lesser” circulation. It is excreted in breast milk, which increases the risk of bleeding in the baby due to impaired platelet function. Breastfeeding should be stopped during treatment.

Impact on the ability to drive a car and other potentially dangerous mechanisms. Due to the possibility of developing adverse reactions from nervous system should be taken with caution.

Release form

10 tablets in a blister pack.

10 tablets in contour-free packaging.

One, two or three contour cell or cell-free packages together with instructions for use are placed in a pack of cardboard boxes.

Self-medication can be harmful to your health.
You should consult your doctor and read the instructions before use.

Every family always has a medicine such as acetylsalicylic acid in their medicine cabinet. But every second person is interested in the following question: “Is acetylsalicylic acid “Aspirin” or not?” This is what we will talk about in our article, and we will also talk about the properties and applications this drug.

A little history

Acetylsalicylic acid was first discovered at the end of the 19th century by the young chemist Felix Hoffman, who at that time worked at Bayer. He really wanted to develop a remedy that would help his father relieve joint pain. An idea where to look the right composition, his father’s attending physician told him. He prescribed sodium salicylate to his patient, but the patient could not take it, as it severely irritated the gastric mucosa.

After two years, a drug such as “Aspirin” was patented in Berlin, so acetylsalicylic acid is “Aspirin”. This is a shortened name: the prefix "a" is an acetyl group that is attached to salicylic acid, the root "spire" indicates spiraic acid (this type of acid is present in the form of an ester in plants, one of them is spirea), and the ending "in" in those distant times, they were often used in the names of medicines.

"Aspirin": chemical composition

It turns out that acetylsalicylic acid is “Aspirin”, and its molecule contains two active acids: salicylic and acetic. If you store the drug at room temperature, then at high humidity it quickly decomposes into two acidic compounds.

That is why Aspirin always contains acetic and salicylic acids; after a short period of time, the main component becomes much smaller. The shelf life of the drug depends on this.

Taking a pill

After Aspirin enters the stomach, and then into the duodenum, the juice from the stomach does not affect it, since the acid dissolves best in an alkaline environment. After the duodenum, it is absorbed into the blood, and only there does its transformation occur and salicylic acid is released. While the substance reaches the liver, the amount of acids decreases, but their water-soluble derivatives become much larger.

And already passing through the vessels of the body, they reach the kidneys, from where they are excreted along with urine. At the exit from Aspirin, a tiny dose remains - 0.5%, and the remaining amount is metabolites. They are exactly what medicinal composition. I would also like to say that the drug has 4 therapeutic effects:

• Preventing blood clots.
• Anti-inflammatory properties.
• Antipyretic effect.
• Removes pain syndrome.

Acetylsalicylic acid has a wide range of applications; the instructions contain detailed recommendations by use. You should definitely read it or consult a doctor.

"Aspirin": application

We found out how acetylsalicylic acid works. What it helps with, we’ll figure out further.

1. Used for pain.
2. At high temperature.
3. At various kinds inflammatory processes.
4. In the treatment and prevention of rheumatism.
5. For the prevention of thrombosis.
6. Prevention of stroke and heart attack.

An excellent drug is acetylsalicylic acid, the price of it will also please everyone, because it is low and ranges from 4-100 rubles, depending on the manufacturer and dosage.

"Aspirin": the fight against blood clots

Blood clots form in those places blood vessel, where there is any damage to the walls. In these places, fibers are exposed, which hold the cells together. Blood platelets are retained on them, which release a substance that helps enhance adhesion, and in such places the vessel narrows.

Most often, in a healthy body, thromboxane is opposed by another substance - prostacyclin; it does not allow platelets to stick together and, on the contrary, dilates blood vessels. When the vessel is damaged, the balance between these two substances shifts, and prostacyclin simply stops being produced. Thromboxane is produced in excess, and the platelet clump grows. Thus, blood flows through the vessel more and more slowly every day. This can later lead to a stroke or heart attack. If acetylsalicylic acid is constantly taken (the price of the drug, as already noted, is more than affordable), then everything changes dramatically.

The acids contained in Aspirin prevent fast growth thromboxane, help remove it from the body. Thus, the drug protects blood vessels from blood clots, but it is worth taking the medicine for at least 10 days, since only after this time do platelets restore their ability to stick together.

Acetylsalicylic acid as an antipyretic agent

Due to the fact that this drug has the ability to dilate blood vessels, the secretion human body heat is removed much better - the temperature drops. Acetylsalicylic acid from temperature is considered the best drug. In addition, this drug also acts on the thermoregulatory centers of the brain, giving it a signal to reduce the temperature.

It is not advisable to give this medicine to children as an antipyretic because of its strong irritant effect on the stomach.

Aspirin as an anti-inflammatory and pain reliever

This drug also interferes with the inflammatory processes of the body, it prevents the release of blood to the sites of inflammation, as well as those substances that cause pain. It has the ability to enhance the production of the hormone histamine, which dilates blood vessels and increases blood flow to the site inflammatory process. It also helps strengthen the walls of thin blood vessels. All this creates an anti-inflammatory and analgesic effect.

As we found out, acetylsalicylic acid is effective against temperature. However, this is not its only advantage. It is effective for all types of inflammation and pain occurring in the human body. That is why this drug is most often found in home medicine cabinets.

"Aspirin" for children

Acetylsalicylic acid is prescribed to children for fever, infectious and inflammatory diseases and severe pain. It should be taken with caution by children under 14 years of age. But for those who have reached the age of 14, you can take half a tablet (250 mg) in the morning and evening.

Aspirin is taken only after meals, and children should definitely crush the tablet well and wash it down with plenty of water.

Contraindications

Acetylsalicylic acid (this is “Aspirin”, as most people call it) can not only benefit the body, but also harm it. It is considered a very aggressive agent.

The first thing you should not do is to use an expired drug, since Aspirin can irritate the gastric mucosa, which will ultimately lead to an ulcer. In addition, those who have gastrointestinal diseases should take the drug only as prescribed by a doctor and it is best to take the medicine with milk. People with kidney and liver diseases should also take it with extreme caution.

Women during pregnancy are not recommended to take the drug, as there is evidence that it can adversely affect the development of the fetus. And you should not use it before childbirth, as this will weaken contractions or may cause prolonged bleeding.

If you think that acetylsalicylic acid is completely harmless, the instructions say something completely different. It has a lot of contraindications and side effects. Before use, you need to weigh all the pros and cons.

Conclusion

So, let's summarize. What does acetylsalicylic acid help with? This drug helps with elevated temperature, from the formation of blood clots, it is an excellent anti-inflammatory and analgesic.

Even though the drug has serious contraindications for use, it is promised a bright future. Currently, most scientists are looking for additives that could reduce harmful influence funds for individual organs. There is also an opinion that other drugs will not be able to displace Aspirin, but, on the contrary, it will have new areas of application.

Every day, millions of people open their home medicine cabinets in search of aspirin. It is taken for headaches, hangovers, and in many other cases. The medicine is so familiar that rarely does anyone look at the instructions to find out what acetylsalicylic acid helps with. But is this drug so safe, how can it help and harm the body?

One of the most famous medicines is aspirin. Many people trust only him: it is inexpensive, tested over several generations. If your health worsens - you have a headache, a fever, or symptoms of ARVI appear, then aspirin becomes your salvation. Those who have had too much alcohol also resort to it. Even if you have a stomach ache, the same pill is used.

Over the years of “work” as an analgesic and antipyretic agent, acetylsalicylic acid has acquired a good reputation among patients. This drug is used all over the world and consistently demonstrates high efficiency. In addition, aspirin can prevent the formation of blood clots and is prescribed to older people to thin the blood and prevent strokes.

At the same time, doctors began to suspect that aspirin was not as harmless as it previously seemed. Studies have shown that this medicine often provokes internal bleeding. If taken regularly and uncontrolled, it can cause serious violations in the functioning of the gastrointestinal tract (including causing ulcers). There have been recorded cases of the development of other pathologies due to constant use of the drug. Thus, due to the ability of acetylsalicylic acid to increase vascular permeability, the composition of the blood may change, which negatively affects the clotting process.

There have been rumors that in some countries aspirin has become a banned drug. This is not true. It’s just not prescribed to children under 15 years of age, pregnant women, breastfeeding women, and those who suffer from diseases of the digestive system. Acetylsalicylic acid is useful only for those individuals who are at risk for cerebral hemorrhage. Healthy people can take 1-2 aspirin tablets, but this should only be done if absolutely necessary. To avoid unpleasant (and dangerous) side effects, it is better not to abuse it.

Every medicine, even one as well-known and accessible as aspirin, should be used as directed. The main indications for its use are the following diseases and conditions:

• fever;
• headache (including migraine);
• circulatory disorders (including blood supply to the brain);
• thrombosis;
• heart attack;
• rheumatism;
• pain of various origins.

During the cold season, acetylsalicylic acid can be especially useful. What does it help with? From the temperature that accompanies the infectious-inflammatory process. It is preferable to knock it down with water-soluble tablets or powders. The pop contains not only acetylsalicylic acid, but also vitamin C, which will help you fight a cold faster. If you only have a regular aspirin tablet on hand, you need to crush it. Effervescent aspirin is diluted in 50-70 ml of water at room temperature. The powder is poured into hot water.

Aspirin should not be taken on an empty stomach! You should take the tablet with a large portion of water or jelly, or even better, use milk for these purposes. The standard dosage is 0.25-1 g 3 to 4 times a day.

If the temperature lasts longer than 3 days, then you should stop taking acetylsalicylic acid and immediately call a doctor.

Today, more efficient and safe drugs to combat fever - based on paracetamol or ibuprofen: Panadol, Paracetamol, Efferalgan. The likelihood of side effects when taking them is much lower than when using aspirin.

Many people have experience treating headaches with aspirin. The result is not always successful. So does acetylsalicylic acid help with headaches? If a person is suffering from ordinary pain (and not a migraine) and takes the pill at the first sign of discomfort, then yes, this drug will be effective.

If a headache strikes an adult healthy person at work, you can take a loading dose of acetylsalicylic acid - 2 tablets. If you have the opportunity to rest, then you shouldn’t risk it, it’s better to take 1 tablet.

Aspirin cannot be taken for a long time, so if the discomfort does not go away for several days, then you need to stop taking it and get examined, since headaches are a symptom of 40 diseases!

IN pharmacy assortment you can find more potent drugs of the same spectrum. They cost much more, but they also act quickly and much more delicately. These are Imet, Nurofen, Ibuprom.

Withdrawal (or hangover) syndrome is a painful condition that deprives a person of his ability to work and brings a lot of inconvenience. Many people know that aspirin is a good helper for someone who has drunk too much. Acetylsalicylic acid will provide relief from a hangover, but will only eliminate external manifestations poisoning (that is, headache, aching joints and muscles), but not the poison itself, will not help free the body from ethanol breakdown products. Drinking aspirin is allowed no earlier than 6 hours after drinking alcohol.

The best option to eliminate hangover syndrome- effervescent aspirin. It contains adsorbents that remove toxins. The tablet is diluted in large quantities water - this will reduce dehydration.

To others known drug, which will “heal” after drinking too much is Alka-Seltzer.

How to take aspirin to thin the blood?

A problem like thick blood, becomes relevant in old age. On the background hormonal imbalance platelet aggregation decreases, which leads to the appearance of blood clots. After 40 years (for women) and 45 years (for men), it is recommended to take blood thinning medications. And the first on their list is acetylsalicylic acid.

Aspirin is often prescribed to prevent thrombosis in adulthood. To do this, the drug should be taken for a long time (lifelong) in very small doses. The tablets are taken in the evening before bed with water. In an emergency, the tablet should be chewed or placed under the tongue. The daily dose of acetylsalicylic acid is 100 mg.

The drugs Cardiomagnyl, Warfarin, Aspercard have a similar effect.

Aspirin can not only be taken orally, but also used externally. In cosmetology, acetylsalicylic acid is often used for acne. To do this, apply a mask to the problem area. It’s easy to prepare: just crush a few tablets and dilute cool water, bring to a mushy consistency and apply to acne for 5-7 minutes.

When does aspirin become poisonous?

Before you swallow another aspirin pill, it is advisable to make sure that you have no contraindications to taking it. First of all, this applies to women, since the drug cannot be taken during pregnancy and breastfeeding.

Medicines based on acetylsalicylic acid should not be taken if you have the following pathologies:

• ulcer;
• internal bleeding;
• kidney and liver diseases;
• nasal polyps in combination with asthmatic syndrome;
• thrombocytopenia;
• allergy to active ingredients.

For patients who suffer from gout, gastritis, anemia and cardiac dysfunction, it is better to obtain a doctor's permission before taking aspirin.

If the child is under 15 years old, then it is better not to conduct experiments and refuse treatment with aspirin, since WHO does not recommend this to avoid unforeseen complications. IN as a last resort, it is better to give preference to an effervescent drug: it has a more gentle effect on the digestive tract.

To minimize or completely eliminate side effects, you should not take the medicine for longer than 2-14 days, and the largest daily dose should not exceed 3 g (and it should be divided into 2-3 doses).

It is believed that 1-2 tablets of aspirin will not cause harm. In most cases this is true. But even short-term use of acetylsalicylic acid can cause the following undesirable reactions:

• nausea, heartburn, loss of appetite;
• vomiting, stomach pain;
• disturbances in liver function;
• dizziness;
• hearing loss;
• bleeding;
• skin rashes.

An overdose of the drug is extremely dangerous.

Acetylsalicylic acid is an effective antipyretic and analgesic. With the advent modern analogues The medicine was included in the list of obsolete because it has many side effects. The drug may be harmful to children and is therefore not recommended for use.

The medicine is available in the form of traditional tablets and effervescent tablets. The drug is taken after meals, washed down with a large volume. warm water, alkaline liquid or milk will also work.

The dosage of the medicine is mainly determined by the doctor. You can take no more than 1000 mg of the drug at a time, but not less than 40 mg. On average, a single dose is 250 or 500 mg of the active substance.

You can take the medicine several times a day. After one dose, at least 4 hours should pass. If we are talking about a child, then the maximum amount of active substance per day for him is three grams.

Depending on the purpose of taking the medicine, the duration of its use is determined. If it is used, then treatment should not exceed three days. When used for migraines, it should be taken for no more than a week. Otherwise, there will be a danger to human health.

From temperature

An increase in body temperature is not a signal to reduce it. If it does not exceed 38.5 degrees during an infectious disease, then the body is able to cope with it on its own. Higher temperatures require taking an antipyretic.

• For children under 4 years of age, the dosage is a quarter of a tablet;
• From 5 to 9 years, the single dose increases to 0.5 tablets;
• Children over 10 years old can take 1 tablet.

For headaches

Acetylsalicylic acid helps with migraines. If we are talking about a child, then this medicine should be used as a last resort and only for older children. A single dose is no more than 0.5 or 1 tablet. After which you need to sleep or rest. Do not forget, the drug eliminates pain, but does not cure the disease.

For toothache

The drug is able to fight. Of course, its effect is not immediate and does not completely relieve pain. Efficiency directly depends on the causes of the ailment.

The drug is not able to completely eliminate dental problem. It is aimed at eliminating the feeling of discomfort. Because active substance does not relieve inflammation, but only alleviates the course of the disease.

For acne

Acne becomes a real problem for teenagers. Good for fighting them this medicine. It relieves inflammation, kills bacteria and dries the skin.

Grind one tablet and mix with water. Apply the solution to the problem area of ​​the skin. You can also use a mask. To prepare it you need three tablets, four drops of water and five grams of honey. The pulp is mixed and applied to the face. The duration of one procedure is 15 minutes.

Acne medication is used no more than once a week. Otherwise, it will lead to dry skin.

To thin the blood

The drug allows you to improve your blood condition, but only if long-term use. It can be taken both for treatment and for preventive purposes. If it is needed normalize blood consistency short time, then prescribe 1 tablet per day.

For prevention, a quarter is enough. It is taken before bed after meals. It is recommended to dissolve the tablet and wash it down with water.

Can it be given to children?

Regular use of the drug can lead to the development of Reye's syndrome, since children's body has an undeveloped defense system. In more early age Aspirin is used only as prescribed by a doctor.

The main contraindications include:

• Individual intolerance to components;
• Ulcerative and renal diseases;
• Problems with foldability blood;
• Liver diseases;
• Aspirin asthma.

If you neglect these restrictions, then there is a high probability of side effects:

• The functioning of the stomach is disrupted;
• Poor urine excretion;
• Blood creation deteriorates;
• From nose goes blood;
• Headache, tinnitus and dizziness appear.

Analogues and price

The cost of the medicine is low. On average, the price ranges from 5 to 15 rubles per package.

There are many analogues of the drug. The most popular are and. Their use is safe for children. They reduce well high temperature. Can be used to treat children over 1 month of age.