Duspatalin® - price, cheaper analogues, list of Russian and imported substitutes. "Duspatalin": what it helps with, reviews, analogues

Undoubtedly, in the media you can find many advertisements for various medicines. Some really help, others have no effect at all. So should you trust advertising? medical supplies? Today we will tell you in detail about Duspatalin and introduce you to customer reviews to find out whether “Duspatalin is really the answer to irritable bowels.”

Instructions for use of the drug

Although Duspatalin is an effective antispasmodic, which can eliminate pain and spasm, before starting use you should read the instructions to find out if you have any contraindications to the use of this drug.

It's not always the same medicine fits different people. We strongly recommend that you consult with your doctor first to correct purpose dosage.

Composition and release form

Main active substance The drug Duspatalin is mebeverine hydrochloride (Mebeverinum), which blocks sodium channels in the myocyte membrane, which prevents the entry of sodium ions into the cell, thereby stopping contraction muscle fibers and the spasm is relieved.

pharmachologic effect

Duspatalin is a myotropic antispasmodic and has a direct effect on the smooth muscles of the intestine. It eliminates spasms without affecting intestinal motility, so the digestion process is not disrupted.

Mebeverine, the main active ingredient, selectively acts on the smooth muscles of the gastrointestinal tract, due to which spasm and pain associated with it disappear.

Prices in pharmacies

Duspatalin is affordable drug and is available in most pharmacies, so you don’t have to look for it for a long time. The cost of one package, however, leaves much to be desired, since the average price is 600 rubles.

Below you can find specific prices for Duspatalin in online pharmacies:

• E-Apteka: capsules – 496 rubles, tablets – 638 rubles;
• ZdravCity: capsules – 525 rubles, tablets – 630 rubles;
• Apteka.ru: capsules – 519 rubles, tablets – 619 rubles;
• GorZdrav: capsules – 471 rubles, tablets – 642 rubles;
• Piluli.ru: capsules – 524 rubles, tablets – 650 rubles.

Analogues of Duspatalin

You don’t always want to spend money on an expensive drug, and not everyone has such an opportunity. That is why it is necessary to know analogues of Duspatalin, which will be much cheaper, their prices and how they differ.

An analogue may or may not be similar in active substance. Of course, if you were prescribed Duspatalin, then if you take an analogue, then only an identical one. Such medicines include:

• Niaspam 200 mg (India) – average cost 380 rubles;
• Sparex 200 mg (Russia) - average cost 360 rubles.

Incomplete analogues differ in the active substance, but they do similar action, being antispasmodics and painkillers. Below are cheap analogues of Duspatalin with prices:

• Papaverine (tablets) – from 15 rubles;
• Drotaverine (tablets) – from 45 rubles;
• No-shpa (tablets) – from 60 rubles;
• Trigan-D (tablets) – from 80 rubles;
• Trimedat (tablets) – from 280 rubles;
• Buscopan (tablets) – from 370 rubles;
• Spascuprel ( homeopathic tablets) – from 380 rubles;
• Dicetel (tablets) – from 475 rubles.

We remind you that before using any of the drugs listed above, you should carefully read the instructions for use.

Niaspam and Sparex

Drugs such as Niaspam and Sparex are complete analogues of Duspatalin. The active ingredient contains the same mebeverine in an amount of 200 mg, and the price category is the same. But what is better to choose?

Both drugs are available in capsule form and have the same amount of active ingredient. As additional ingredients The same substances are used, such as colloidal silicon dioxide, talc, magnesium stearate and gelatin.

The drugs vary by manufacturer. Sparkex is an analogue produced in Russia by the pharmaceutical company Canonpharmaproduction CJSC. Niaspam is produced in India by SunPharmaceuticalIndustriesLtd.

Patients often say that Sparex does not have the desired effect, but there are those who are completely satisfied with the domestic drug.

It is logical to state that in in this case Everything is strictly individual and you will have to select the drug yourself.

Incomplete analogues

In addition to Niaspam and Sparex, there are a number of incomplete analogues that can be used if Duspatalin has run out or is not available in the pharmacy suitable drug. These medications are based on a different active ingredient, but one that can relieve pain in the gastrointestinal tract.

Papaverine

Papaverine is based on the active substance papaverine hydrochloride. The drug is produced in Russia and Belarus.

On the shelves of pharmacies you can find various shapes Papaverina – injection solution, tablets and rectal suppositories.

One tablet of the drug contains 10 mg of the active substance and additional components in the form of starch, talc, sugar and stearic acid. The injection solution contains 20 mg of papaverine hydrochloride per 1 ml. Also, 20 mg of active ingredient is contained in 1 suppository.

Papaverine is a myotropic antispasmodic and is able to relieve spasms in the smooth muscles of the gastrointestinal tract. The question is which form of the drug is best to use. Rectal suppositories are absorbed faster through the walls of the colon and the effect of the drug is achieved faster. In cases where the use of suppositories causes discomfort, it is more logical to use tablets.

Drotaverine

Drotaverine contains the active substance of the same name. The drug is produced both in Russia and Ukraine. Drotaverine not only has an antispasmodic effect, which should be taken into account by people with heart disease.

It is produced in the form of tablets and injection solution in ampoules. It is not recommended to use the injection solution yourself, but you can use tablets. Tablets are available in two types - containing 40 and 80 mg of the active substance.

The drug has an antispasmodic effect and reduces gastrointestinal motility and smooth muscle tone, which reduces spasm and reduces pain.

No-shpa

No-spa is perhaps the most popular antispasmodic in the world. pharmaceutical market for several decades now.

It is surprising that the active substance in the drug is drotaverine, also contained in the drug of the same name at a lower cost.

Excipients also differ little. The only difference is that Drotaverine uses potato starch, and No-shpe uses corn starch.

No-spa has three release forms:

• No-shpa tablets containing 40 mg of active ingredient;
• No-shpa Forte tablets containing 80 mg of active ingredient;
• No-shpa injection solution in ampoules with a concentration of 20 mg/ml.

The action is similar to Drotaverine, but most patients note that No-shpa copes with the assigned tasks better.

Trigan-D

Action drug Trigan-D is based on two active substances - dicycloverine and paracetamol, due to which the drug It is not only an antispasmodic, but also an antipyretic and analgesic.

Trigan-D is produced in India and in one single form - in tablets, each of which contains 500 mg of paracetamol, 20 mg of dicycloverine hydrochloride.

Trimedat

Trimedat, like all the drugs described above, is a myotropic antispasmodic that regulates gastrointestinal motility. In addition, it helps restore the physiological activity of the intestines, which has a positive effect on the entire gastrointestinal tract.

Trimedat is produced in Russia in the form of tablets. The pack contains 10, 20 or 30 tablets. 1 tablet of Trimedat contains 100 or 200 mg of the active substance (maleatatimebutine). Reviews from patients prove the positive effect of using Trimedat.

It is also noteworthy that Trimedat is one of those drugs that are dispensed from pharmacies without a prescription.

Buscopan

Buscopan is the best incomplete analogue of Duspatalin successfully completing the task.

Hyoscine butyl bromide, which is the basis of the drug, has a powerful antispasmodic effect, due to which healing effect is achieved quickly.

As additional substance Paracetamol acts as a muscle relaxant.

Buscopan is available in two forms - tablets and rectal suppositories. It is noteworthy that the tablets are produced in France, while the candles are produced in Italy. Both forms of this medicine contain 10 mg of the active substance, but the effect of suppositories is achieved faster due to rapid absorption through the intestinal walls.

In addition, the drug is widely popular not only among people with gastrointestinal diseases, but also among pregnant women to relieve pain.

Dicetel

Dicetel is another incomplete analogue of Duspatalin. Pinaverium bromide is the main active ingredient of the drug and has an antispasmodic effect, eliminating spasms of smooth muscles and improving blood flow to the walls of the gastrointestinal tract.

Dicetel is produced in France in the form of tablets containing 50 or 100 mg of pinaverium bromide. It is taken not “before”, but during meals, no more than twice a day. Only a doctor can prescribe a higher dosage.

The drug has both positive and negative reviews. Moreover, the latter often mention the emergence allergic reaction. To avoid allergies and side effects Do not take the drug without consulting a doctor.

Spascuprel

The drug Spascuprel, although it is homeopathic, has not only an antispasmodic effect, but also relieves pain and muscle tension in the gastrointestinal tract.

The drug differs from the others in that the active ingredients are natural elements, such as colocynth extract, ammonium bromide, white hellebore and atropine sulfate.

Spascuprel is produced in Germany, and On the shelves of pharmacies you can find both tablets and ampoules for injection.

The tablets are intended for sublingual resorption. You can use no more than 3 tablets per day. There are no strict instructions for use, but it is recommended to take them 30 minutes before meals.

Spascuprel is an excellent solution for those who do not want to use potent drugs. But it is worth noting that it is recommended to use the drug prescribed by the doctor and not to self-medicate.

Diseases gastrointestinal tract V modern world Not unusual. A fast pace of life, poor diet, stress and other reasons lead to functional and more serious illnesses Gastrointestinal tract. The article will talk about modern drug whose name is “Duspatalin”. Its analogues will be considered, and a comparative assessment of some duspatalin substitutes will be given.

Duspatalin - brief instructions

Mebeverine hydrochloride – active substance drug. ICD-10 code – ATX A0ZA A04. Refers to anticholinergic drugs. Release form: tablets (135 g of active substance) and capsules (200 g of mebeverine). Produced in the Netherlands.

Mebeverine has a pronounced antispasmodic property. The effect of the drug is selective, it mainly affects smooth muscles digestive system, while intestinal motility remains unchanged.

When is duspatalin indicated?

Direct indications for use are:

• irritable bowel syndrome (flatulence, colic, constipation, diarrhea);
• spasm of the gastrointestinal tract (GIT);
• painful sensations in the epigastric region (abdominal pain);
• pathologies of the biliary tract.

Contraindications

Mebeverine is not used in following cases:

• individual intolerance;
• pregnancy and lactation;
• childhood up to 10 years.

How to take duspatalin?

Usually the treatment plan is prescribed by the doctor. The duration of the appointment is also agreed with the specialist. According to the instructions for use, for example, if we consider duspatalin in capsules, the drug is taken 1 capsule twice a day.

Possible adverse reactions

Duspatalin rarely causes side effects; negative symptoms such as constipation, diarrhea, nausea, headache or dizziness, and allergic reactions are quite rare.

The average cost of duspatalin in Russia is 500–600 rubles.

Duspatalin analogues are cheaper

It can't be said that this remedy has an exorbitant price, but still the search for cheaper substitutes does not stop. This means that this price is not suitable for everyone, especially in cases where the patient suffers chronic disorders The gastrointestinal tract and duspatalin have to be purchased repeatedly. Good inexpensive means exist, we will discuss them below.

Duspatalin is usually changed for two reasons: the price is not satisfactory, or the patient experiences adverse reactions. First of all, you need to know that only a specialist can replace the drug; there can be no amateur activity in this matter.

As cheap analogues Russian production The following drugs may be considered:

• mebeverine;
• sparex;
• papaverine.

• dicetel;
• trimedate;
• no-shpa;
• buscopan;
• Odeston;
• niaspam.

Let's take a closer look at the presented drugs.

Russian analogues of duspatalin

Mebeverine

Russian mebeverine is a structural analogue of duspatalin, since their active substance is completely the same. The drug is produced in capsules, the action of which has a prolonged effect. The drug is prescribed for heartburn, nausea, and spastic pain in the epigastrium. The drug is also used for pancreatitis, when the patient develops vomiting. The drug is not recommended for use under 18 years of age. As for possible side effects, they are the same as for duspatalin.

average price capsules - about 350 rubles.

Sparex

Like mebeverine, sparex is a structural analogue of duspatalin. Indications, contraindications, and side effects are not particularly different. Sparex has a capsule release form. The drug is not recommended for use under 12 years of age. IN in rare cases, short-term, the drug is prescribed before this age, for example, with severe pain in the epigastrium. Sparex can be used for peptic ulcer stomach, pancreatitis, colic, localized in the liver and kidneys.

The price for a package of sparex is about 350 rubles.

Papaverine

The active ingredient is papaverine hydrochloride. The product has been successfully used to relieve liver and renal colic. Recommended for pylorospasm, cholelithiasis, cerebral vascular spasm. The product is available in tablets, suppositories, and solution for injection.

Tablets in a dosage of 40 mg No. 20 cost about 60 rubles.

Foreign analogues

Niaspam

The drug has a myotropic effect. Country of origin: India. The active ingredient is mebeverine hydrochloride. It is a structural analogue of duspatalin. The main task of Niaspam is to eliminate functional disorders of the large intestine. The drug has a pronounced antispasmodic effect. The drug is not recommended for children under 12 years of age.

Capsules 20 mg No. 30 cost about 380 rubles.

Trimedat

The drug is classified as an antispasmodic that relieves pain and discomfort in the gastrointestinal tract. The name of the active substance matches the name of the drug. Trimedat is available in tablets. Manufacturer: Korea.

The price for trimedat is around 450 rubles.

Odeston

The active ingredient is hymecromone. Country of origin: Poland. The drug is available in tablet form. Odeston has a pronounced antispasmodic effect and also has a choleretic effect. Compared with duspatalin, the drug has more wide application. It is also prescribed in the following cases: all problems associated with dysfunction of the gallbladder (dyskenesia, cholecystitis and others).

The disadvantage of odeston is that it has contraindications for use: hemophilia, severe kidney and liver pathologies, childhood, gastrointestinal ulcers, others. Adverse reactions more often associated with migraines and allergic manifestations.

The price for a package of Odeston is 360 rubles.

Buscopan

The drug is produced in France and Austria. Refers to cholinomimetics, perfectly prevents spasms of the intestines (small and large), stomach and gall bladder. It has two forms of release: tablets and suppositories. The product is based on the active substance butyl bromide hyoscine.

Buscopan is effective for various spasms, it is prescribed for attacks of colic, intestinal dysfunction, pylorospasm, cardiospasm and other problems.

Contraindications for use: myasthenia gravis, pulmonary edema, atherosclerosis, others. Possible adverse reactions: severe drowsiness, dry mouth, tachycardia.

The average price for a buscopan is around 370 rubles.

No-shpa

The product is produced in France. It is a cheap substitute for duspatalin.

Many doctors believe that no-spa is one of the cheapest substitutes for duspatalin. Has a pronounced myotropic effect. It has a strong analgesic effect, so it is often used to relieve renal and hepatic colic, as well as attacks of other etiologies. Release form: tablets and solution for injection. The active substance is drotaverine (antispasmodic).

• Indications: spasms various organs. Approved for use in obstetric practice.
• Contraindications: severe functional disorders liver, kidneys, heart, children under 6 years of age, lactation period, individual intolerance to the composition. Side effects occur extremely rarely: migraine, insomnia, tachycardia, hypotension, dyspepsia.

A package of 40 mg tablets No. 100 can be purchased for 250 rubles.

Dicetel

Pinaveria bromide is the main active ingredient. Refers to m-anticholinergics. Produced in France. Release form: tablets.

It is used to relieve spasms and colic in diseases of the gastrointestinal tract. Dicetel is also used as a preparation for endoscopic procedures. The drug is well tolerated, sometimes adverse reactions occur: diarrhea, nausea, allergies.

Currently, dicetel costs slightly less than duspatalin, and in some pharmacies it is even more expensive.

When choosing antispasmodics, patients sometimes do not know what is best to buy. Specialists often offer several drugs to choose from, and it turns out that the right of choice remains with the patient. Let's compare several pairs of antispasmodic drugs and try to determine which one is more effective and cheaper.

Comparative assessment of duspatalin and its analogues

Trimedat or duspatalin - which is better?

The main indication for the use of these drugs is irritable bowel syndrome. Pharmacological group, to which these drugs belong - myotropic antispasmodics.

Fundamental differences:

• main cast;
• auxiliary staff;
• company manufacturer;
• price;
• operating principle;
• release form;

Mebeverine is the active substance of duspatalin, trimebutine is the main component of trimedate. Both drugs have tablet form; only duspatalin has capsules.

For severe pain, it is better to use duspatalin; for constipation, trimedate is recommended. Duspatalin has an advantage as an antispasmodic.

Trimedat is not used in children under three years of age, duspatalin is allowed only after 10 years of age. During the lactation period, the drugs in question are not used. During pregnancy, only in exceptional cases, in the second and third trimesters trimedate can be used.

The price of trimedate is lower, approximately 15%.

Sparex or duspatalin - what to choose

The drugs are structural analogues, the composition differs only in auxiliary components. The Russian manufacturer produces only capsules, and duspatalin (Netherlands) also has tablets, where the dosage of the drug is lower. This allows therapy to be adjusted when the daily dosage needs to be reduced.

Since the products have identical composition, the indications and contraindications are basically the same. Sometimes side reactions are observed, for example, when taking duspatalin there are none, but there is a reaction to Sparex; rather, such “side effects” are associated with some kind of auxiliary substance.

Whatever one may say, price remains one of the priorities when choosing a medicine. No matter how much they praise, for example, foreign drug, it is difficult to convince a person that only it needs to be purchased. This is especially problematic if the patient’s purchasing power is low. Therefore, specialists should always take this point into account and select funds according to the financial capabilities of the patient.

It should be noted that imported drugs are not always better. Practitioners have experience in using various drugs, therefore, a competent doctor will always tell the patient which remedy to choose.

Comparing the price of duspatalin and sparax, we can conclude that the first product is 30–40% more expensive.

Duspatalin or Niaspam

These means are structural analogues, therefore, according to pharmacological action identical. The capsule dosages of these products are also the same. The effect of the drugs is prolonged.

The drugs differ only in cost, manufacturer and composition of excipients. Niaspam can be used from 12 years of age, duspatalin is allowed from 10 years of age.

Duspatalin is 30% more expensive than Niaspam.

Herbal analogues that relieve intestinal spasms

There is a certain category of patients who do not want to take any chemical drugs, considering such therapy to be fatal to the body. Of course, you can’t think so unequivocally; sometimes you can’t do without certain medications. For example, it is impossible to cure tuberculosis without antibiotics.

Herbal remedies are usually included in complex therapy and contribute to more rapid recovery body. Let's look at a few simple recipes, relieving spasms, where cheap analogues of duspatalin are medicinal plants.

Medicinal mixture for intestinal spasms (infusion)

Compound:

• sage;
• plantain;
• peppermint;
• St. John's wort;
• cottonweed.

You will need 10 grams of dried herbs, 5 grams of mint, and 15 grams of other herbs. All herbs need to be mixed, the collection is ready. In order for the collection to be beneficial, it is very important to properly harvest medicinal plants. If you have no experience in this matter, it is better to purchase finished products at the pharmacy.

Now let's move on to preparing the infusion. You need to pour 5 grams of the collection with boiling water (200–300 ml). Leave for 20 minutes, strain. Divide the resulting infusion into three parts and drink throughout the day.

Peppermint infusion

Many have heard that mint not only calms the nervous system, but is also an excellent antispasmodic. Mint infusion is taken for headaches, intestinal spasms, and menstrual pain. Mint is brewed both dry and fresh. Usually take a dessert spoon of dry raw materials per glass of boiling water. After 15 minutes the infusion is ready. It is recommended to drink this infusion twice a day.

If you are outside the city, please note that a lot of wild mint grows near ponds and lakes, in its own way. medicinal properties it exceeds peppermint. Therefore, do not be lazy, pick mint and dry it. This preparation will help out more than once with nervous excitement and stomach pain.

Horsetail, yarrow and wormwood

The mixture of these plants has a beneficial effect on the smooth muscles of the gastrointestinal tract. Horsetail and yarrow take 20 grams each, then add 10 grams of wormwood. Everything is mixed. The resulting mixture is poured with 0.5 liters of boiling water. Leave for about two hours, then filter. Take 50 ml 4 times a day.

The course of treatment is at least five days, even if the pain in the intestines has gone away on the second day. It is necessary to “calm” the gastrointestinal tract as much as possible, especially in cases where the patient has irritable bowel syndrome.

Dill (infusion)

Dill - excellent remedy to prevent and relieve intestinal spasms. In summer it is better to infuse fresh dill seeds, in winter - dry ones. Pour 200 ml of boiling water over a tablespoon of seeds and let stand for 15 minutes. You can also take dill greens in the summer. It is brewed in the same way.

People with gastrointestinal problems need to constantly include dill in their diet. If there is a baby living in the house, stock up dill water(buy at the pharmacy), it relieves colic perfectly.

Flaxseed (infusion)

This plant belongs to the plantain family. The infusion is prepared as follows: pour a tablespoon of herbs into 300 ml of boiling water. Leave for about 20 minutes, strain. Take a tablespoon every four hours. The course of therapy for gastrointestinal diseases lasts two weeks. A month later, the treatment is repeated.

Conclusion

Duspatalin is a worthy and noteworthy drug that eliminates pain and spasms in various disorders of the gastrointestinal tract. Despite this, many patients are interested in analogues.

The article provided a list of cheap analogues and gave a comparative description of duspatalin and some of its analogues. We hope that the information presented will help patients understand not so simple questions medicine and pharmacology. Be healthy!

Prohibited during pregnancy

Prohibited when breastfeeding

Has restrictions for children

Allowed for older people

Has limitations for liver problems

Has limitations for kidney problems

Duspatalin blocks the penetration of calcium ions into the smooth muscle tissue of the digestive tract, reduces the concentration of calcium in cell membranes, stops their interaction with proteins, which leads to relaxation of the muscle fibers of the muscles of the digestive organs. The active component relaxes the gallbladder sphincter and bile ducts, which promotes a fast and active food processing process. The main component in the medicine is mebeverine.

The medication is prescribed for the following diseases of the digestive system:

• severe pain in the abdominal area due to spasm in the intestines;
• pathologies of the biliary tract;
• cholecystitis;
• irritation in the intestines;
• colic.

The antispasmodic is not used in patients with allergies to the medication and in the treatment of children under 10 years of age. Not carried out clinical trial regarding the use of the drug during pregnancy and breastfeeding. Patients over 10 years of age should take 1 capsule of Duspatalin twice a day.

Among the negative reactions of the body to the drug are the following:

• allergic reactions - dermatological rashes, urticaria, skin itching and Quincke's edema;
• digestive disorders - constipation, dyspepsia, nausea;
• The central nervous system reacts to the medication with body fatigue, dizziness and headaches of varying intensity.

Duspatalin is one of the most effective antispasmodics, but has one drawback - its high price. Therefore, many patients need information about cheap analogues of Duspatalin.

Prices for the drug and analogues of Duspatalin

Not all similar medications to Duspatalin have a budget price. The price depends on the country of origin of the medicine. Domestic medicines are 2-3 times cheaper imported substitutes. The list of Duspatalin analogues is presented in the table

Researchers in therapeutic action

There are analogues of Duspatalin with different structural compositions, but having the same therapeutic direction. The effectiveness of these medications is no lower than the effectiveness of Duspatalin.

Buscopan

Buscopan is produced in the form of suppositories for rectal use and in tablets. The main component is hyoscine butyl bromide. Buscopan is prescribed for spasms:

• in the digestive system - intestinal colic;
• genitourinary organs – colic in the kidneys;
• with exacerbation of gastric ulcer pathology;
• gallbladder.

Buscopan is not used in the treatment of children under 6 years of age, as well as for the following pathologies:

• myasthenia gravis;
• sclerosis of cerebral arteries;
• megacolon;
• glaucoma;
• pulmonary and cerebral edema;
• BPH;
• cardiac disorders (arrhythmia);
• obstruction in the intestines;
• allergy to medication.

Buscopan can be used in therapy during pregnancy, except for the 1st trimester. During lactation, you need to switch the baby to formula feeding and then start therapy.

Take 1-2 tablets three times a day. Suppositories should be inserted into the rectum, 1 piece three times a day. After relieving acute symptoms, take 1 tablet 1-2 times a day for 1-2 days. The same scheme for using suppositories.

Negative reactions appear during long-term therapy or with incorrect dosage and are expressed in the following symptoms:

• dry skin and mucous membranes;
• skin redness;
• eczema;
• arrhythmia;
• hives;
• shortness of breath and difficulty breathing;
• fluid retention in the body.

Dicetel

Dicetel is produced in tablets with the main component - pinaverium bromide. The drug has an antispasmodic effect on pathology, relaxing the muscles internal organs, reduces tone, improves blood supply to the walls of the digestive organs.

Dicetel is used for the symptomatic treatment of pain in the following pathologies of the gastrointestinal tract:

• gastritis and duodenitis;
• pylorospasms and enteritis;
• esophagitis and cholecystitis;
• intestinal colic;
• dyskinesia of internal organs.

The medication is also used to prepare the patient for instrumental diagnostics epigastric organs (x-ray and endoscopy).

Dicetel is not used if the patient has the following concomitant diseases:

• atony and intestinal obstruction;
• colitis of ulcerative etiology;
• sensitivity to components;
• megacolon of toxic type.

It is not recommended to take the medicine before bed. During pregnancy, the drug is prescribed only in as a last resort and except for the 1st trimester, and during lactation, taking the medication is possible only after transferring the child to artificial feeding.

Dicetel should be taken with food. Single dosage– 0.05 g, dosing frequency per day – 3 times. Before diagnostics, take the medication three times a day, 0.2 g, for 3 days.

The medication rarely causes side effects, and only sometimes patients report symptoms of allergies, digestive disorders and headache.

Spascuprel

Homeopathic medicine with an antispasmodic effect on the digestive tract. Herbal medicine is used to relieve spasms urinary tract, urinary and gall bladder, intestinal and gastric spasms of smooth muscles. Also, medication is often prescribed to eliminate spasms of muscle fibers.

Do not use the medicine in the treatment of children under 3 years of age, as well as in case of hypersensitivity of the body to the plant components in the herbal medicine. During pregnancy, as well as during lactation, the medication can be used as prescribed by a doctor and under his personal supervision.

Dosages are prescribed by the doctor personally. Standard dosages are:

• 1 tablet under the tongue three times a day. Should be taken 30 minutes before meals;
• in case of a sharp exacerbation of the disease - 1 tablet every 15 minutes for 2 hours;
• therapeutic course – 14-21 days.

Very rarely occur negative reactions when taking a medication, sometimes an allergy may occur in the form of skin rash and itching.

Russian analogue drugs

Russian analogues of Duspatalin are in the low price segment and are available to many patients. Medicines are not inferior in effectiveness to expensive ones to the original remedy, which also helps relieve acute pain during spasms in the organs of the digestive system.

Sparex

Sparex is an antispasmodic drug with myotropic action that affects smooth muscle fibers in parts of the digestive system and the walls of the large intestine. The active component mebeverine hydrochloride inhibits phosphodiesterase, does not affect peristalsis and does not have anticholinergic effects.

The medication is prescribed to children over 12 years of age for abdominal pain, as well as to adult patients for the following diseases:

• spasms in the gastrointestinal tract;
• colic in the intestines;
• irritable bowel syndrome.

It is prohibited to take Sparex tablets in the following cases:

• allergy to the composition of the medicine;
• up to 12 years;
• lactation period;
• porphyria.

Pregnant women can take the medicine only as prescribed by a doctor. During lactation, Sparex therapy should be started only after the child is switched to feeding with artificial formulas.

Dosages are prescribed by the doctor based on the patient’s age, as well as the development of the pathology. Average doses of medication:

• 135 mg (1 tablet) three times a day;
• 100 mg (1 tablet) 4 times a day.

The dosage must be gradually reduced until a stable therapeutic effect occurs.

Side effects from taking the medication:

• dizziness and slight headache;
• diarrhea or constipation;
• allergies in the form of urticaria, exanthema and Quincke's edema.

Trimedat

Trimedat is a medication that normalizes intestinal motility, as well as the activity of the gastrointestinal tract. Trimebutine in the composition of the drug affects the enkephalinergic system of the intestines, and is also the main regulator intestinal peristalsis. The medication acts on the smooth muscles of the digestive organs and acts as an antispasmodic in hyperkinetic pathologies.

The medication affects all organs in the gastrointestinal tract:

• reduces tone and spasms in the esophageal sphincter;
• promotes normal operation and gastric emptying;
• affects all parts of the intestine and restores peristalsis.

The drug is prescribed for the following gastrointestinal pathologies:

• gastroesophageal reflux pathology;
• dyspeptic disorders in the gastrointestinal tract;
• irritable bowel;
• obstruction in the gastrointestinal tract during the postoperative period;
• preparation for instrumental diagnostics of the gastrointestinal tract;
• gastrointestinal motility disorders in children.

Treatment with Trimedat is not prescribed in the following cases:

• child's age under 3 years;
• allergy to the composition of the medicine;
• pregnancy;
• lactation.

In the first trimester of pregnancy, it is strictly forbidden to take the drug, and starting from the 2nd trimester, it can only be taken as prescribed by a doctor and under his strict supervision. During lactation, taking pills can be started after the newborn has stopped breastfeeding.

Dosages directly depend on the patient’s age:

• 3-5 years – 25 mg three times a day;
• 5-12 years – 50 mg three times a day;
• from 12 years – 100-200 mg 3 times a day.

At secondary prevention In the event of relapses of pathology, it is necessary to take 100 mg three times a day for 2-3 months. Negative effects are rare and may result in allergic skin reactions.

Cheap similar products

Patients who cannot purchase Duspatalin due to the high price can use analogues for treatment, which are cheaper than Duspatalin, but are not inferior to it in quality and effectiveness.

Drotaverine

This is an antispasmodic drug that is used for disorders of the gastrointestinal tract. The active component drotaverine in the drug inhibits the synthesis of phosphodiesterase and the accumulation of cAMP in the intracellular space. These actions lead to relaxation of smooth muscle fibers.

The drug is effective in reducing spasms of muscle or nervous etiology. The medication affects the muscles vascular membranes, urological organs, gastrointestinal tract organs. The drug is produced in tablets.

Drotaverine is used in the treatment of pathologies of the biliary system:

• cholecystitis and pericholecystitis;
• cholelithiasis and cholangitis;
• cholangiolithiasis;
• papillitis

The medication is used in the treatment of genitourinary pathologies:

• nephrolithiasis and pyelitis;
• urethritis and cystitis;
• Tenesmus in the bladder:
• dysmenorrhea and spasms in the fallopian tubes;
• uterine contractions, which can cause miscarriage.

Used to relieve spasms in the gastrointestinal tract in the following diseases:

• gastritis and ulcerative pathology stomach;
• irritation syndrome in the large intestine;
• pancreatitis;
• flatulence and constipation.

Also, the drug is often used to relieve headaches of vascular origin.

Drotaverine is not used in therapy for the following pathologies:

• hypersensitivity;
• renal and liver failure;
• myocardial failure and blockade of 2-3 degrees;
• glaucoma.

Also not used in pediatrics under 6 years of age and during lactation. Drotaverine is prescribed with caution in the following cases:

• hypertension and sclerosis of the coronary arteries;
• prostate hyperplasia;
• glaucoma;
• pregnancy.

Taking the medication may cause the following side effects:

• allergies - urticaria, skin rash, anaphylaxis (shortness of breath, decreased blood pressure and respiratory arrest), dermatitis;
• neurological disorders - dizziness, insomnia and headache;
• cardiac manifestations – tachycardia, bradycardia, decreased blood pressure;
• digestive disorders - nausea and vomiting, constipation or diarrhea.

Dibazol

The medication is prepared in a solution for injections with active ingredient– bendazole. Dibazol is a hypotensive, immunostimulating drug with an antispasmodic effect. The drug effectively blocks the synthesis of phosphodiesterase, which leads to a decrease in the tone of smooth muscle fibers in the internal organs and systems of the body - respiratory, vascular, digestive, genitourinary, and nervous.

Dibazol is used in the treatment of such pathologies:

• cupping hypertensive crisis;
• vascular spasms in the limbs and brain;
• therapy of obliterating atherosclerosis;
• cholecystitis;
• ulcerative pathologies of the gastrointestinal tract;
• pylorospasm;
• colic in the gastrointestinal tract;
• renal colic;
• polio;
• facial nerve palsy.

Dibazol should not be used in the treatment of:

• hypersensitivity;
• epilepsy.

For pregnant and lactating women, the drug is prescribed as a last resort and under the strict supervision of a doctor. Dosages depend on the pathology and the stage of its progression, as well as on the age of the patient. For children in the treatment of neurological pathologies, the following is prescribed per day:

• 0-1 year – 1 mg;
• 1-3 years – 2 mg;
• 4-8 – 3 mg;
• 8-12 – 4 mg;
• over 12 years old – 5 mg.

To relieve a hypertensive crisis in adult patients – 30 mg (6 ml)-40 mg (8 ml) IM and IV. During treatment nervous pathologies Once a day, 5 mg of the drug into the muscles for 5-10 days. The therapeutic course must be repeated in a month.

Taking this medicine may cause allergy symptoms, headache and dizziness, as well as feeling hot and sweating.

Niaspam

Antispasmodic medication with myotropic effects on the smooth muscles of the gastrointestinal tract. The medication eliminates muscle spasms in organs and does not affect intestinal motility.

Niaspam is prescribed for the following disorders in the functioning of the gastrointestinal tract:

• spasms in the intestines;
• colic;
• irritable bowel syndrome;
• gastritis;
• ulcerative pathologies.

In children over 12 years of age, it is prescribed for disorders of the gastrointestinal tract that provoke abdominal pain. The medicine is not prescribed for pediatric patients under 12 years of age, or for those with an allergy to the medication. During pregnancy, Niaspam can be taken under medical supervision. The active components of the drug do not pass into breast milk, so there is no need to interrupt lactation during therapy

You need to take 1 capsule of Niaspam in capsules. 2 rubles/day 20-30 minutes before meals. Therapeutic course is 14-21 days. Adverse reactions of the body to taking the medication:

• allergy;
• dizziness;
• constipation.

Duspatalin is a drug that belongs to the group of myotropic antispasmodics. The main substance of the drug is mebeverine hydrochloride, which has an antispasmodic effect on muscle layer gastrointestinal tract. This medicine is often prescribed to people with acute pain in the intestines and stomach, colic of the intestines and gallbladder, as well as dysfunction of the colon.

When it enters the body, the active component is broken down by enzymes, breaks down into metabolic products in the liver and is excreted mainly by the kidneys.

It is not recommended to take drugs for children under 12 years of age. Duspatalin can be used in the treatment of older children to eliminate spasm of the muscular layer of the digestive organs, accompanied by discomfort and painful sensations in a stomach. Doctors do not recommend treatment with the drug for pregnant and breastfeeding women. Also, the medication is contraindicated if you are allergic to its components.

Dizziness and malaise are considered the main symptoms side effect medicines. Swelling, rashes or itching are less common. An overdose is manifested by digestive disorders and increased excitability. The drug may affect concentration and driving. Duspatalin has many cheap analogues.

Duspatalin is available in the form of yellow dragees in a gelatin capsule, which slowly dissolves in digestive tract and has a prolonged period of action. The drug is packaged in strips of 30 capsules, each containing 200 mg of the main substance.

Duspatalin has big list cheaper analogues, completely identical in the active component. Below is a list of the most common ones:

1. Aspasmin.
2. Mebsin Retard.
3. Meverin.
4. Milorin.
5. Morease.
6. Spark.
7. Sparex.
8. Niaspam.
9. Mebeverine.

Aprofen

Aprofen is a medicine in the form of a white powder that dissolves well in water. The drug is used to relieve spasms and dilate blood vessels. The active substance is aprofen, which inhibits cholinergic receptors, reduces the tone of the muscular layer of the stomach, intestines and urinary tract, dilates blood vessels and affects the tone of the muscles of the uterus.

The medicine is used in cases of spasms of the gastrointestinal tract and genitourinary systems s, most often with colic and ulcers, as well as with severe vasoconstriction of cerebral vessels, endarteritis and weak labor.

Glaucoma, hypersensitivity to the composition, dysfunction prostate gland, deterioration in the functioning of the liver and kidneys are contraindications for prescribing the drug. It is not recommended for pregnant and breastfeeding mothers to use it.

Side effects on the body can manifest themselves as follows:

• dyspeptic symptoms;
• drying out oral cavity and excessive constant thirst;
• impaired urine output;
• a sharp decrease in the concentration and activity of the central nervous system(NS).

When consumed large quantity substances may cause dizziness, nausea, malaise, nervous system excitation, high blood pressure, impaired excretion of urine from the body. To eliminate these symptoms, it is necessary to rinse the stomach, give adsorbents, and treat the symptoms.

Aprofen is available not only in powder form, but also in the form of an injection solution and tablets, which are taken 3-4 times a day, and the effect occurs within half an hour. It differs from Duspatalin in its release form and a wider range of indications for use.

Dibazol

Dibazol is a cheap analogue of Duspatalin, the cost of which is several times less. It differs from the main drug in its pronounced antihypertensive properties, release form and a large number of indications for use. The active substance of Dibazol is bendazole. Available in the form of a solution for injection.

Diabazol injections dilate blood vessels, lowering blood pressure and improving blood flow, stimulate immune system and dock sharp pain. By limiting the entry of calcium into cells, the tone decreases muscular system organs. The drug also improves the transmission of nerve impulses in synapses, thereby stimulating the functioning of the nervous system. Doctors prescribe it to patients with elevated blood pressure, with vascular spasm, atherosclerosis of the extremities, with spasm muscle tissue organs of the digestive and genitourinary systems, with ulcers, colitis and facial paralysis.

Treatment with Dibazol is prohibited for people with hypersensitivity to the composition, if epileptic seizures and dysfunction of the heart, kidneys, or liver. It is recommended to use it with caution in elderly patients. During pregnancy and lactation it is prescribed in rare cases, when absolutely necessary.

Injections of 6-8 ml are given daily for 10 days, repeated every other month. Children under 1 year of age are prescribed 1 mg, and the dosage is increased with age.

Side effects include rash, swelling, hyperemia, nausea, headaches, malaise, and a sharp decrease in blood pressure. An overdose occurs when an excessively large amount of a substance is administered at one time and is manifested by indigestion, headaches and a feeling of fever. To eliminate these signs, the stomach is washed, adsorbents are administered, and symptomatic treatment is carried out.

Dicetel

Dicetel is a drug that is available in tablet form and is widely used as an antispasmodic. This effect is achieved due to pinaverium bromide, which is a blocker calcium channels, that is, eliminates muscle spasms. It breaks down into metabolic products in the liver and is excreted in feces or urine.

The medication is used to normalize the functioning of the digestive organs, reduce excretion of hydrochloric acid, improving blood supply to internal organs. The drug relieves pain that occurs during inflammatory processes stomach, duodenum, gall bladder, esophagus, intestinal colic, enteritis, pyloric spasms. It is often recommended to patients before undergoing X-ray examination and endoscopy of the gastrointestinal tract.

Dicetel is contraindicated in case of hypersensitivity to its components and decreased muscle tone. Doctors do not recommend taking the medicine before bed. Dicetel is rarely prescribed to pregnant women; if prescribed during lactation, the child should be switched to artificial formulas.

Take 1 tablet with food, 3 times a day. The maximum effect appears half an hour after administration, and the highest concentration of the substance in the blood is observed after an hour.

During treatment with the drug, adverse reactions may occur:

• from the gastrointestinal tract: abdominal pain, nausea, vomiting, diarrhea;
• skin reactions: itching, rashes, erythema.

No cases of overdose have been recorded, since only 1/10 of the substance is absorbed in the digestive tract. The drug does not affect the work of cardio-vascular system. It differs from the main drug in fewer side effects.

Mebeverine

Mebeverine is a widely used antispasmodic that is available in capsule form. Active component The drug is mebeverine, which affects sodium channels and blocks the entry of sodium into the cell, which provokes a decrease in the tone of the muscle layer of the digestive system and a decrease in its peristalsis.

Indications for the use of Mebeverine are the following pathologies:

• spasms of the stomach and intestines;
• irritable bowel syndrome accompanied by dyspeptic disorders;
• gallbladder dysfunction;
• inflammatory processes in the biliary tract.

The medication is contraindicated for persons with allergies to the components of the drug, intestinal obstruction, or porphyria. It is also prohibited for women to take Mebeverine during pregnancy and breastfeeding.

For patients with impaired renal, heart and liver function, treatment with the drug is carried out under the close supervision of the attending physician. The medicine may cause nervous system disorders in people with genetic diseases circulatory system.

Directions for use: swallow the capsule whole with a small amount of water, as the capsule provides long action medicines. To obtain the desired effect from treatment, you must take Mabeverine twice a day.

Possible side effects:

• increased excitability;
• rash, swelling, itching;
• digestive disorders.

An overdose may result in overexcitation of the nervous system. To eliminate these symptoms, gastric lavage is performed and adsorbents are administered. Mebeverine differs from the main drug in its active substance, mechanism of action and side effects.

No-shpa

- This is one of the most common antispasmodics. The main substance is drotaverine hydrochloride. The mechanism of action is similar to papaverine and belongs to phosphodiesterase type 4 and calmodulin inhibitors. Available in the form of tablets and solution for injection. It has a wide spectrum of action and is used to eliminate muscle spasms of the gastrointestinal tract, inflammation of the biliary tract, acute headaches and gynecological pain. Has a vasodilating effect. It has no effect on the central nervous system.

No-spa is contraindicated in the following conditions:

• glaucoma;
• prostate dysfunction;
• hypersensitivity to the components of the drug;
• acute dysfunction of the heart, liver or kidneys;
• period of pregnancy and breastfeeding.

During childbirth, No-shpa is prescribed exclusively by doctors. Take 1 tablet. several times a day or during attacks of severe pain. Often used by obstetricians and gynecologists to quickly dilate the cervix.

Taking the medication may cause side effects:

• sudden jumps in blood pressure;
• dizziness, rapid heartbeat;
• dyspeptic symptoms;
• itching, redness skin, swelling.

The main symptoms of overdose are considered to be a violation heart rate, decreased myocardial conductivity, which can lead to the death of the patient.

Different from Duspatalin wide range actions and active substance. According to studies, Duspatalin is more effective in relieving gastrointestinal pain with fewer side effects.

Trimedat

Trimedat is a drug in the form of white oval tablets that contain the active substance trimebutine maleate. The drug as an antispasmodic is often used for gastroesophageal disease, dyspeptic disorders, muscle spasms of the digestive system, colic, intestinal obstruction, preparation for x-ray examination and endoscopy, impaired intestinal motility.

Trimebutine acts on the enkephalinergic system of the intestine, changing its peristalsis. It also affects the muscular layer of the sphincter, pushing chyme from the stomach into the intestines. The active substance is absorbed in the intestine a few hours after administration, the metabolic products disintegrate in the liver and are excreted from the body in the urine.

The drug can be prescribed to children from 3 years of age in small quantities for disorders of the digestive system and abdominal pain. Hypersensitivity to the components of the drug and age under 3 years are contraindications for use. It is not recommended to use Trimedat for early pregnant women and nursing mothers.

The most common side effects are rashes, itching and redness of the skin. There are no known cases of overdose.

The drug differs from Duspatalin in its mechanism of action, price, release form, dosage and active substance. Most often, in cases of gastrointestinal spasm, Duspatalin is used. Trimedat is prescribed to patients with dyspeptic symptoms, most often manifested by constipation.

Duspatalin – medicinal product with myotropic, antispasmodic effect.

Affects the smooth muscles of the gastrointestinal tract without affecting normal intestinal motility. Does not have anticholinergic effect. Another positive effect is that the medication does not accumulate in the body after a single use, but in in full force excreted through the urinary canals.

On this page you will find all the information about Duspatalin: full instructions on application to this drug, average prices in pharmacies, complete and incomplete analogues of the drug, as well as reviews of people who have already used Duspatalin. Would you like to leave your opinion? Please write in the comments.

Clinical and pharmacological group

Antispasmodic myotropic action.

Conditions for dispensing from pharmacies

Dispensed with a doctor's prescription.

Prices

How much does Duspatalin cost? The average price in pharmacies is 550 rubles.

Release form and composition

The active substance of Duspatalin is mebeverine hydrochloride:

• 1 capsule – 200 mg;
• 1 tablet – 135 mg.

Dosage forms:

1. Film-coated tablets: have round shape and white color (10 pcs in blisters, in a cardboard pack of 1 or 5 blisters; 15 pcs in blisters, in a cardboard pack of 1, 2 or 6 blisters; 20 pcs in blisters, in a cardboard pack of 1, 2, 3, 5 or 6 blisters).
2. Long-acting capsules: size No. 1, opaque hard gelatin structure white, are marked “245” on the body; Inside the capsule there are granules of white or almost white color (10 or 15 pieces in blisters, 2 or 3 blisters in a cardboard pack).

Pharmacological effect

The antispasmodic and myotropic effect of Duspatalin is to prevent contraction of muscle fibers during spasms of internal organs. The drug relaxes the smooth muscles of the gastrointestinal tract without significantly affecting intestinal motility.

After reception single dose, the drug is completely excreted in the urine within 24 hours and does not accumulate in the body.

Duspatalin is a misotropic antispasmodic with dual action. It relieves spasms without causing a decrease in intestinal muscle tone. Its mechanism of action does not depend on the autonomic nervous system, so the use of Duspatalin eliminates the occurrence of dry mouth, weakness, problems with stool and urination, and tachycardia. It can be taken for prostate hypertrophy, glaucoma, and insufficient urination.

Indications for use

What does it help with? According to the instructions, Duspatalin is used for the following conditions:

1. Biliary colic;
2. Intestinal colic;
3. Gallbladder dysfunction;
4. Spasmodic pain in the lower abdomen;
5. Irritable bowel syndrome;
6. Condition after surgery to remove the gallbladder;
7. Secondary spasms of the gastrointestinal tract caused by diseases of other systems and organs (for example, pain during or);
8. Functional disorders of the gastrointestinal tract, accompanied by severe pain syndrome in the abdominal area (in children over 12 years old).

The drug is also prescribed as a symptomatic remedy that eliminates spasms, discomfort and pain in the intestines.

Contraindications

The drug is not prescribed in case of hypersensitivity patient to one of its components, if the patient is allergic. Prescribe it with caution to pregnant women and during lactation.

Use during pregnancy and lactation

Taking the drug is completely safe for pregnant women, since it affects only the smooth muscles of the digestive organs and does not affect the blood vessels and uterus. In addition, the medicine has positive influence on the release of bile and juice in the pancreas in duodenum, relaxes the sphincter of Oddi. Does not affect fetal development. Duspatalin is prescribed only with the consent of the doctor, having assessed the ratio possible risk and benefits for mother and fetus.

Pregnant women are prescribed only capsules. They cannot be combined with various antispasmodics such as No-shpa, Papaverine or Drotaverine hydrochloride. Prescribe two capsules twice a day. The duration of treatment is carried out until disappearance pain symptoms and normalization of the patient's condition. The withdrawal of the drug is carried out according to the usual scheme for adults and gradually.

Instructions for use

The instructions for use indicate that the dosage depends on dosage form Duspatalin.

• Film-coated tablets: orally, daily dosage can be 135 mg 3 times or 100 mg 4 times a day. After achieving what you want clinical effect, the dose is recommended to be reduced gradually over several weeks.
• Extended release capsules: taken orally, 20 minutes before meals, swallowed whole and washed down with a sufficient amount of water (100 ml or more). Recommended dosage is 200 mg 2 times a day, morning and evening. The period of application is not limited.

After achieving the desired clinical result, the drug should be gradually discontinued over 3 to 4 weeks. Typically, stopping pills is done as follows:

• 1st week - take one whole Duspatalin tablet before breakfast and lunch, and half before dinner.
• 2nd week - take Duspatalin twice a day, one whole tablet - before breakfast and dinner, that is, in the morning and in the evening.
• 3rd week - take Duspatalin in the morning before breakfast, one whole tablet, and in the evening before dinner - half.
• Week 4 – take one tablet per day in the morning before breakfast.

Cancellation of capsules occurs as follows:

• For one to two weeks, you should take only one capsule per day in the morning, before breakfast. Then stop using the drug completely. In this case, after using the drug for a week, one capsule per day, you need to take a break for two days and evaluate your well-being. If no painful symptoms of spasms in the gastrointestinal tract have developed, then you can no longer take the drug. If marked discomfort, then you should take Duspatalin, one capsule a day, for another week, and only then finally stop taking the drug.

The above scheme for gradual drug withdrawal represents unified recommendations developed by leading Russian clinics specializing in the therapeutic treatment of diseases of the digestive tract.

Side effects

Only during a course of treatment can individual intolerance to the drug become clear, which is expressed in signs of an allergic reaction such as urticaria:

• the occurrence of edema of various localizations;
• rashes and redness on the skin.

There have been extremely rare cases of the following side effects of Duspatalin:

• increased heart rate;
• weakness and fatigue;
• increased sweating.

If you notice one of the above symptoms, you should contact a gastroenterologist, who will adjust the dose or replace the medication.

Overdose

In reviews of Duspatalin, the consequences of an overdose are very rare. If this does happen, it is expressed mainly in increased excitability central nervous system.

Treatment for overdose consists of gastric lavage and taking activated charcoal.

special instructions

Since under the influence of the drug, patients may experience a decrease in blood pressure and dizziness, during the period of therapy they should refrain from driving or driving complex mechanisms requiring increased concentration of attention from the patient.

Drug interactions

No interactions with other medications have been identified. Therefore, Duspatalin can be combined with other medications.

Since there are cases of dizziness developing under the influence of Duspatalin, it is necessary during the period of treatment with this drug to refrain from any activities that are associated with the need to have high concentration attention and speed of psychomotor reactions. This includes driving with caution during the treatment period.

Alcohol compatibility

Taking Duspatalin and alcohol are incompatible things. Alcohol has irritant effect, increases spasms of blood vessels and excretory ducts.

As a result, we can conclude that alcohol and drugs have completely opposite effects. Therefore, when treating with Duspatalin, you need to stop drinking alcohol, because the effect of the drug will either decrease or stop altogether.