What does Omez help with? Instructions for use. The right approach: how to take Omez

Inhibitors proton pump(PPI) were introduced in medical practice almost a quarter of a century ago. Today these are the most prescribed medications for the treatment of many diseases of the digestive system. The ancestor is Omez and its analogues. What kind of drug is this and what is it for? Let’s try to figure it out.

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general information

Omez is trade name a medicine that has become widespread in our country since the 90s of the last century. The drug was created on the basis of, which is considered the first chemical compound from the class of antisecretory agents.

It has the properties of a weak alkali and suppresses the production of hydrochloric acid in the stomach due to the inhibitory effect on the proton (cellular) pump - this is the name of the biochemical process occurring in the parietal islets of the stomach.

The effect of omeprazole on acid formation is effective because it inhibits not only basal (nighttime) but also stimulated daytime secretion of hydrochloric acid, regardless of the type of food consumed.

This allows you to use Omez for heartburn for any gastrointestinal diseases associated with increased acidity, V gastric juice and (or) with the presence of gastroesophageal reflux as the main cause of this unpleasant symptom. The antisecretory effect of omeprazole occurs within 60 minutes, reaches its maximum after 2 hours and lasts up to 24 hours.

Others important properties are:

• protection of the mucous membrane;
• reduction in scarring time ulcerative defects in the stomach or duodenum;
• destruction of HP infection - Helicobacter pylori (therefore, patients may have a question whether Omez is an antibiotic or not);
• reversible hypertrophy of producing cells in the stomach.

Important! Full recovery secretory activity occurs approximately within 5 days after discontinuation of the drug.

Omez method of application

Omez is produced by the Indian pharmaceutical company Dr. Reddy's, an analogue of Omeprazole, is produced by various domestic companies. Release form – capsules of 10 and 20 mg active substance for oral administration. There is also a form for intravenous infusion - this is a lyophilisate (40 mg of omeprazole in 1 bottle) for preparing a solution with 5% glucose.

Who is the medicine indicated for?

Most gastroenterologist patients know about PPIs and understand what they are buying, antibiotic or not. Omeprazole can be purchased at a pharmacy to relieve heartburn without a prescription. However, it is more correct for the doctor to prescribe a course of treatment, explain the need to take Omez according to the instructions for use and tell him why it is needed.

The medicine is effective for many diseases digestive system and can be used as a main or additional therapeutic agent, for monotherapy or as part of a complex of measures.

possible side effects

Main indications for use:

• treatment of exacerbations of duodenal and gastric peptic ulcers, as well as prevention of relapses;
• therapy for GERD (gastroesophageal reflux disease), associated with the reflux of acidic stomach contents into the esophagus;
• relief of hypersecretory pathologies, which include Zollinger's disease, gastrointestinal ulcers caused by stress, etc.;
• participation in schemes for the destruction and removal (eradication) of HP in patients with proven infection as prescribed by a doctor or according to instructions for use approved for Omez for gastritis or peptic ulcer;
• treatment and prevention of gastropathy caused by damage to the mucous membrane of the stomach and duodenum before or after long-term use of NSAIDs (non-steroidal anti-inflammatory drugs);
• prevention of the development of acid aspiration pneumonitis (non-infectious inflammation of the pulmonary parenchyma).

Indications for use for children

Is it possible to give medicine to children who have similar diseases, or prescribe Omez during pregnancy? Security and high efficiency the drug has been proven only against certain pathologies of the gastrointestinal tract that arise in childhood. Namely:

• GERD – for patients weighing more than 20 kg (from 4-5 years);
• duodenal ulcer associated with Helicobacter pylori in children of the same age category.

Important! Expectant mothers and breastfeeding women are allowed to use this product, as indicated by the instructions for use that come with Omez.

In the form of an intravenous solution, it is intended exclusively for the treatment of ulcers complicated by the development of gastrointestinal bleeding.

Methods of application

How to take Omez correctly, before or after meals - there are clear instructions on this matter. Omeprazole-based drugs should be drink half an hour before meals 1 or 2 times a day depending on the diagnosis and condition of the patient.

The capsule must not be chewed; it must be taken with enough plain water to swallow.

If Omez has difficulty swallowing, can children or other people open the capsule and mix the powder with food? This technique is allowed, only fruit juice must be used for dissolution, but not milk or carbonated drinks.

The prepared mixture cannot be stored. It is not advisable to take the drug after eating.

When treated with Omez, the method of application will differ depending on the patient’s diagnosis:

1. For ulcers of the duodenum and stomach, 20 mg is prescribed 1 or 2 times a day (half an hour before breakfast and dinner). The duration of therapy is determined individually from 2 to 8 weeks or more.
2. For GERD, the dose is from 1 to 4 capsules per day for 1-2 months depending on the severity of esophagitis. For maintenance therapy, Omez is prescribed as an intermittent course of treatment or on demand at a minimum dose of 10-20 mg in the morning.
3. For hypersecretory pathologies, the dosage can reach 80-120 mg per day, divided into 3 doses. Instructions for use for gastritis with high acidity allow long-term use of 20 mg of the drug as prescribed by a doctor and, especially with concomitant hiatal hernia and other causes constant heartburn and the risk of developing Barrett's disease (precancerous degeneration of the epithelium).
4. To carry out eradication treatment for patients with HP and duodenal or gastric ulcers, the drug is included in 3 or 4-component treatment regimens together with two antibiotics and bismuth preparations. The duration of such a scheme is usually 14 days. The dose for the treatment of adults is 2 capsules of 20 mg per day (morning and evening).
5. For the prevention and treatment of NSAID gastropathy, 20 to 40 mg of the drug is prescribed every day for the entire duration of treatment with nonsteroidal drugs.

For what diseases is medicine prescribed?

How to take Omez before adulthood is decided by the attending physician. Usually pediatric dose does not exceed 20 mg per day, and the duration of therapy is 2 months. ABOUT It is advisable to drink mez during pregnancy according to indications from the second and third trimester in the minimum possible dosage.

Cautions

Instructions for use and doctors always pay attention to possible side effects and contraindications for treatment with a particular medicine.

Who should not take omeprazole-based medications:

• children under 2-4 years of age (body weight less than 20 kg) with peptic ulcer disease or GERD;
• children and adolescents under 15 years of age with other gastrointestinal diseases (gastritis, etc.);
• persons with indications of allergies and individual intolerance to omeprazole in the anamnesis;
• patients with severe osteoporosis;
• patients with malabsorption syndrome (deficiency of enzymes that digest sugar);
• persons receiving treatment with cytostatics;
• insufficiently examined people with suspected stomach cancer.

The drug has contraindications

The frequency of adverse reactions depends on the patient’s initial level of health and the presence of concomitant pathologies. In most cases the drug is well tolerated. The following are possible unwanted effects from treatment:

• anaphylactic reactions - Quincke's edema, bronchospasm;
• sleep disturbance, excitability or depression;
• dizziness, migraine;
• dermatitis, skin itching, urticaria;
• vague abdominal pain, nausea, stool retention, flatulence, stomatitis;
• elevated liver enzymes, very rarely hepatitis;
• muscle weakness, pain in the spine and joints, bone fractures, development of osteoporosis.

During treatment it is necessary pay attention to emerging alarming symptoms (weight loss, pain, black stools or vomiting blood), which may indicate the presence of malignant neoplasms.

Important! Suppression of acid formation leads to a smoothing of the clinical picture, so there is a danger of delaying the diagnosis of cancer.

Reduced acidity in the stomach is fraught with the development pathogenic microflora in the small intestine, which increases the risk of intestinal infections. Long-term treatment with PPIs leads to decreased absorption of vitamin B12 and the development of anemia. To avoid undesirable consequences It is possible provided that you follow the recommendations of the doctor who prescribed the drug.

Video: Omez for the treatment and prevention of ulcers and lesions of the duodenum

Omez with its indications for use has gained wide popularity due to its effectiveness and affordable price. Today this drug is trusted by patients of gastroenterologists all over the world, as it helps improve the quality of life of patients with various diseases digestive organs.

A myriad of new medicines, problem solvers concerning the functionality of the gastrointestinal tract and its specific organs, could not relegate to the background such an effective and material affordable drug like Omez. Instructions for use of the drug Omez are intended for medical workers and patients, contains information on how to take the medicine (before meals or after), what it is prescribed for, what is the current price for pharmaceutical market, what reviews consumers give and what analogues experts prescribe.

Description and general characteristics

The development of diseases such as gastritis and peptic ulcers is caused by increased acidity of digestive juice. Poor nutrition- a common factor that provokes an increase in the level of hydrochloric (hydrochloric) acid. In such circumstances, it is important to prescribe the drug Omez, the purpose of which is to reduce the secretion of hydrochloric acid.

Manufacturer - India, international name- omeprazole.

The medicinal form of release is capsules that are resistant to digestive juice and soluble in the intestines. There are three types of capsules, distinguishable by size No. 3, No. 2, No. 0, 0.01 g, 0.02 g and 0.04 g, respectively, with a characteristic mark on the capsules in the form of the name of the drug OMEZ.

Pharmacological group - PPI (proton pump inhibitor), antisecretory, acid-controlling drug.

The instructions for use describe the following composition of the drug Omez (capsules No. 2 are discussed in this annotation). The main component is omeprazole, a white powder that has an inhibitory effect on the secretion of hydrochloric acid.

Auxiliary components:

• mannitol (sexahydric alcohol)
• sodium salt of lauryl sulfuric acid
• lactose
• sodium hydrogen phosphate
• sucrose
• hypromellose.

Cardboard packaging contains:

• No. 3 / No. 2 - three aluminum strips of 10 capsules each and instructions for using the drug Omez.
• No. 0 - four blisters of 7 capsules and instructions.

There are also the following types and forms of medicine:

1. Omez - in the form of an ampoule with lyophilisate for subsequent dissolution and intravenous injection.
2. Omez Insta - powder for preparing suspensions for internal use.
3. Omez D is a capsule containing a couple of active ingredients, omeprazole and domperidone (a prokinetic agent).

One of the main causes of constipation and diarrhea is use various medications . To improve bowel function after taking medications, you need to do it every day. drink a simple remedy ...

Action

Omez counteracts the final phase of hydrochloric acid release by slowing down the intensity of H+/K+-ATPase in the parietal cells of the stomach, thus reducing acid production.

The effect of Omez develops rapidly, an hour or two after taking the tablet and lasts for 24 hours. The maximum antisecretory effect is observed after four days of therapy and is completely completed three to four days after the last medication.

Indications for use

According to the instructions, Omez is prescribed for the prevention of renewed and progressive gastric ulcer and duodenum And in hyperexcretory states:

• Ulcerogenic pancreatic adenoma;
• Ulcers in the gastrointestinal tract caused by stress, trauma;
• SPEA;
• Mastocytosis;
• Gastroesophageal reflux disease;
• In combination therapy for the destruction of spiral-shaped gram-negative bacteria in infected patients with gastric/duodenal ulcers;
• Gastropathy provoked by taking NPPs.
• Prevention of the occurrence of peptic ulcers in pancreatitis;
• Drinking Omez is prescribed for heartburn accompanying pancreatitis;

Contraindications

Use of the drug Omez not assigned:

• During pregnancy and breastfeeding (lactation);
• For children under 18 years of age;
• In case of hypersensitivity to the constituent substances of the drug Omez;

The instructions warn about caution in the use of Omez for people with impaired renal and/or liver function.

Side effects

Taking Omez causes a considerable number of negative side effects, manifested from different organs and systems of the human body, the phenomena occur rarely and disappear after completing the medication.

Side effects that occur when using Omez:

• Hematopoietic system. There are abnormal blood counts, a decrease in the number of platelets and leukocytes in the blood, pancytopenia, agranulocytosis;
• CNS. Tendency to a depressed, depressed mental state; headache and dizziness;
• Gastrointestinal tract. Vomiting, excessive gas formation, disorders such as constipation, diarrhea, abdominal pain. Infrequent phenomena may include: dryness and lesions of the oral mucosa; overestimation of liver enzyme motility indicators; hepatitis with Gospel disease, liver antifunctionality (with severe liver pathologies);
• Musculoskeletal system. Painful sensations in joints, muscles, myasthenia gravis;
• Skin reactions. Itchy rash, allergic exudative erythema, hair loss;
• Immunity. Nettle rash, fever, bronchospasm, Quincke's edema, anaphylaxis;
• Other reactions: increase mammary glands, sweating, feeling “broken”, swelling of the limbs;

Overdose

In case of overdose, side effects are eliminated with symptomatic therapy.

Symptoms of an overdose with Omez:

• Lethargic, sleepy state;
• Foggy consciousness;
• Impaired visual acuity;
• Feeling of dryness in the mouth;
• Cardiopalmus;
• Failures in rhythm and heart rate;
• Feeling of nausea, pain in the head.

Directions for use and doses

Omez capsules are taken 30 minutes before meals, without chewing, with a small amount of liquid. According to the instructions for use, if it is impossible to swallow a whole capsule for certain reasons, the powder contained in it can be mixed into a tablespoon of applesauce and taken immediately with a glass of water.

Prescription of dosage by specialists largely follows standard recommendations according to the instructions:

• Patients with acute ulcers, gastropathy as a result of taking NSAIDs, and reflux esophagitis - 0.02 g. once a day;
• For patients with acute reflux esophagitis - 0.04 g. once a day;

Course of treatment: for esophagitis and stomach ulcers - 30-60 days, for duodenal ulcers - from 14 to 35 days.

• For patients with gastrinoma - 0.06 g (with a possible increase in dose to 0.12 g) in several doses;
• Preventive therapy for acid aspiration pneumonitis - 0.04 g one hour before surgery;
• Prevention of ulcerative relapses - 0.02 g per day.
• For gastritis or ulcers caused by a gram-negative bacteria - Omez is combined with antibacterial drugs(metronidazole), antibiotics (amoxicillin) in the form of “double” / “triple” therapy, the dose is calculated by a specialist;

Interaction with other drugs and alcohol

The drug omeprazole reduces the absorption of ampicillin ester, antifungal agents, iron salts.

Long-term use of Omez in combination with the following drugs does not lead to modification of their concentration in the blood plasma: caffeine, methylxanthine, NSAIDs (diclofenac, piroxicam), ethanol, local anesthetic- lidocaine, etc.

There is no information in the instructions about the compatibility of alcohol and Omez. Drinking alcohol is always a burden on the liver; in combination with drugs, this load increases even more.

What to replace it with?

The action of all PPI drugs is aimed at treating acid-related gastrointestinal diseases. Such antisecretory drugs are worthy substitutes for each other.

Analogues of Omez include:

• Famotidine;
• Ulsepan;
• Pariet;
• Loseprazole;
• Parastamik;
• Peptipak et al.

There are two PPI drugs that are popular analogues of Omez, which are prescribed more often than others - Omeprazole, Nolpaza. Below are tables with general and various properties medicines (price, effect, composition, etc.).

Omez or Nolpaza?

How much does Omez cost?

The cost of the drug is affordable; pharmacies offer all types of Omez and its release forms. The exception is Omez Insta in Ukraine - information on price and availability this tool absent. The table shows average, approximate prices for Omez; exact price data can be obtained directly from pharmacies in your city. The drug is sold without a prescription; it is recommended to take Omez only as prescribed by your doctor.

Video

In case of malfunctions gastrointestinal tract a drug such as Omeza is prescribed.

But important question The question that puzzles interested people is how long Omez can be taken.

Omez or Omeprazole as it is also called, refers to medications that help normalize the production of gastric juice.

Thanks to the relief of symptoms, a person feels much better.

Increased acidity leads to the appearance of erosions and ulcers on the walls of the stomach.

Normalizing the acidity level will serve as a preventive measure not only for the appearance of ulcers, but also oncological disorders in organism.

Restrictions

It is not advisable to take this medicine if you are allergic to any of the components of this drug. It is advisable to take medications only after consultation with your doctor.

How to use

There are two options for the release of such a drug as Omeprazole. For example, powder for intramuscular injection into the body and capsules with microgranules.

It acts very quickly and in 30 minutes can eliminate acute attack gastritis pain. Additionally, it helps eliminate nausea and normalizes acidity levels.

The ideal option would be its combination with Phosphalugel. This medicinal product able to protect the walls of the stomach from damage.

Additionally, Omeprazole fights the cause of stomach ulcers, that is, the Helicobacter pylori bacterium.

How long can Omeprazole be used without interruption?

Like any other medicine, Omez can harm the body if you self-medicate and do not follow the norm when taking pills.

It is also not advisable to take it for a long time. You should stop taking it on the same day when the symptoms stop.

You need to drink them twice a day: before meals in the morning and in the evening before bed.

The course of treatment should be completed within 30 days; if the disease is not advanced, then it must be reduced.

Also, the course of treatment is that the medicine must be taken every day.

How long can you take Omeprazole?

To avoid the occurrence of adverse reactions, you can use the medicine for no longer than 60 days. Moreover, this must be done only under the supervision of a medical specialist.

He will select the necessary method of rehabilitation therapy for a specific disease.

Is it possible to take Omez on a regular basis?

It is impossible to restore the body with the help of one drug; for this it is necessary complex treatment. Self-medication can negatively affect a person’s health.

Restrictions on the use of Omez

It is necessary to take Omez especially carefully if the patient’s age exceeds 50 years.

The problem is that when long-term use the drug may cause improper distribution of calcium.

In this regard, there may be a risk of bone depletion and the risk of bone fracture.

Do not take the medicine during pregnancy and lactation. It is also not advisable for children under one year of age to use Omez.

Sometimes the disease goes away with hidden symptoms or patients take medications to eliminate pain.

Omez can be purchased at a pharmacy even without a doctor’s prescription at any pharmacy.

But it is necessary to consult if, in addition to medications, the patient additionally takes:

1. Ampicillin.
2. Phentytoin.
3. Disulfiram.
4. Diazepam.
5. Blood thinners.
6. Nutritional supplements that contain iron.
7. Medicines for the treatment of AIDS.

You should immediately consult a doctor if, after taking Omeprazole, swelling of the tissues in the throat, face or tongue, breathing problems, or allergies occurs.

It is advisable to call " Ambulance"if the following problems arise: suffocation, dizziness, coughing, reduction muscle tissue involuntary, spasms.

It is also necessary to stop taking the drug if you have diarrhea, nausea, pain in the abdomen, sneezing, swelling of the nasopharyngeal tissue, sharp increase temperature.

Headaches, bloating, and vomiting may also occur.

Contraindications to the use of the drug

There are cases in which the use of a drug such as Omez is strictly prohibited. For example:

1. Individual intolerance to the ingredients of the drug.
2. Impaired functioning of the liver and kidneys. These organs belong to the excretory system, so when taking medications huge pressure is aimed specifically at them. Possible occurrence of chronic or acute diseases.
3. Children. In general, it is not recommended for children of any age to use Omez, but there are a number of examples in which the doctor believes that useful action much more than a side effect.

It works especially well when used with Phosphalugel. It protects the stomach walls from negative influence aggressive components of Omeza.

Side effect

Any drug has both positive and negative effects. It is especially dangerous if these consequences cannot be changed. Possible reactions from the central nervous system.

These may include headaches, dizziness, insomnia, as a last resort, even hallucinations. The gastrointestinal tract may also react negatively.

arise painful sensations, vomiting, diarrhea or constipation. Additionally, muscles may weaken, sweating may increase, and rashes may appear on the skin.

This drug helps to cope with dysfunction of the stomach and restore its normal functioning.

You can also take Omez to prevent seasonal exacerbations.

It is able to protect the mucous membrane of the stomach and duodenum.

jeludokbolit.ru

Rules for taking Omez for gastritis

Many patients experiencing this unpleasant illness, the question arises: “How to take Omez for gastritis?” What kind of drug is this and will it help cure this disease? Omez really treats gastritis, but not all of its types, but only those caused by increased acidity of gastric juice.

Gastritis with high acidity

Omez is used for gastritis if it develops against a background of increased acidity. You can determine that acidity is increased by the following signs:

• Heartburn. This is one of the main symptoms.
• Belching. Belching can vary. If the acidity is low, then the food is poorly digested, so rotten smell. With gastritis with high acidity, it tastes sour.
• Nausea. If the patient has eaten a lot of acidic foods, vomiting occurs.
• The abdomen swells and aching pain appears.

If this acute gastritis, then the symptoms are pronounced, if chronic gastritis - appear after prolonged fasting or after overeating, in case of poisoning, severe stress etc. However, an accurate diagnosis can only be made by the attending physician, according to the FGSD. He will prescribe the correct treatment. Among the medications for gastritis may be Omez.

About the drug

Two types of this drug are available: Omez and Omez D. The capsules of the first contain only omeprazole. They are transparent, colorless, with a pink lid, and contain 20 g of granules. Omez D contains not only omeprazole, but also domperidone. They can be distinguished by appearance: They are white with a purple cap. Preparations for preparing the solution are also produced. They do not contain tablets, but white powder.

This medicine prevents the basal cells of the stomach lining from producing hydrochloric acid. Acidity decreases, a person’s well-being improves. Besides, it climbs antimicrobial effect. Thanks to this drug, an alkaline environment is created in which Helicobacter pylori cannot exist normally. Therefore, it is used both as a primary medicine and as part of treatment.

How many tablets to take

How to take Omez correctly for gastritis? Your doctor should have told you about this. He plans a course of treatment based on the results of the examination. How many days should I take Omez? This is also decided by the gastroenterologist. But on average, if a patient has gastritis with high acidity, the doctor prescribes 1 capsule (20 mg). It should be taken 1 or 2 times a day, for 10 - 14 days. Within 2 hours the medicine will begin to act. Soon the unpleasant symptoms will disappear and the patient will feel better.

If the doctor believes that Helicobacter pylori is the cause of the disease, he will ask you to take 2 capsules of the medicine for 14 days, along with amoxicillin, to treat gastritis with Omez. If it is reflux gastritis, then treatment may take 1 or 2 months, during which the patient will drink 1 or 2 capsules.

You can take this drug for prevention, even if there are no signs of the disease yet, but the doctor has detected increased acid production. In this case, the usual dosage is 1 capsule, which is drunk once a day, 4 hours before bedtime, for 2 weeks. Your doctor can increase or decrease the time of administration and the dose.

How to take the medicine

The drug has instructions for use. You need to stick to it. So, the medicine should be taken on an empty stomach, at least half an hour before meals. It is better to swallow the capsule immediately with water. There is no need to chew it or open it. The capsule must fall into small intestine, where its shell will dissolve. If you have difficulty swallowing the capsule whole, you can open it and pour the contents into 1 spoon of applesauce, and then eat it with one glass of water. If you drink omez gastritis, the instructions for use are important, but it is still better to listen to the doctor’s recommendations.

For what diseases can they be prescribed?

As we have already found out, Omez treats gastritis if this disease is caused by increased production of hydrochloric acid. But Omez can also be used for other diseases. Thus, it helps with exacerbations of duodenal ulcers. It is also prescribed for Zollinger-Ellison syndrome. Taking Omez is recommended for stomach ulcers, erosive gastritis.

This medicine is used both for the treatment of these diseases during exacerbation, and for their prevention. Then they drink this drug for a long time, up to six months, 1 capsule. Can I increase the dose on my own? No you can not. How much and for how long to take this medicine, the doctor must decide.

Before you start drinking the drug, it is advisable to get checked to make sure that there is no malignant tumor. If you start treatment, the medicine may hide the symptoms cancer, i.e. it will be difficult to detect cancer on early stage, and this is precisely what guarantees a cure.

Contraindications

If the doctor insists on taking Omez for gastritis, you should not refuse, this medicine really helps. But it has a number of contraindications. In this case, other, more safe drugs.

• pregnant women;
• young mothers who are breastfeeding;
• children who have not yet turned 12 years old;
• patients who have gastritis with low acidity;
• patients diagnosed with severe kidney and liver diseases;
• for those who have individual intolerance to the components of the drug.

Side effects

U this drug many side effects. But they do not appear if the dosage is accurately calculated. It is important to follow your doctor's recommendations. In this case, side effects should not occur. If they make themselves felt, you can stop the drug, after which they will disappear.

The most common side effects:

• Nausea, vomiting, there may be diarrhea or constipation, sometimes dry mouth;
• Dizziness, headache, bad mood appear (often with concomitant diseases);
• A person suffers from myalgia and arthralgia;
• Allergies may occur.

If there was an overdose, the patient suffers either from drowsiness or from increased agitation, he begins to experience arrhythmia, and increased sweating, headache, blurred vision, possible confusion. Therefore, it is important to use this medicine in the amount recommended by the doctor.

Omez is a modern medicine that helps cope with gastritis, ulcers and other dangerous diseases. Immediately after taking the drug, the symptoms of the disease disappear and the patient’s well-being improves.

Zhivot.info

Omez for gastritis: dosage for adults | How to use Omez for gastritis

The drug Omez or Omeprazole, Gastrozole is one of the most modern and, of course, the most effective medicines. Distinctive feature drugs such as Omez is the creation favorable conditions, at which last stage secretion is inhibited, regardless of what irritating factors it was caused by. Even the most complex and life-threatening conditions of the gastrointestinal tract can be treated with Omez for gastritis.

Omez for gastritis begins to work fully 2 hours after entering the body. Omez at one daily use is able to control the level of gastric juice secretion around the clock, create a favorable and comfortable atmosphere for the functioning of the gastrointestinal tract. At the same time, the medicine for gastritis restores basal secretion and blocks external irritants by acting on gastric receptors.

Omez is available in capsules with a dosage of 20 mg, each of which consists of a special enteric coating and microgranules. The central therapeutic component of the drug is five-methoxybenzimidazole.

Omez should be taken for 2 weeks, one capsule per day. The medicine is guaranteed to help get rid of hyperacidity and symptoms of an irritable stomach. For treatment of reflux esophagitis and erosive esophagitis, you need to take 2 capsules of the drug per day for 5-8 weeks.

For the purpose of prevention, Omez is used in the evening 3 hours before bedtime to prevent acid aspiration.

How to use Omez for gastritis?

If you miss your next dose of medication for some reason, you do not need to take a double dose of the drug. It is very dangerous. In such a situation, it is better to consult your doctor and check with him the necessary dosage to continue this course of treatment.

You should not take Omez in cases hypersensitivity to some individual components of the drug. Omez has no other contraindications, but with long-term use there are quickly passing side effects such as nausea, diarrhea, headache and allergic reaction.

For what diseases should Omez be used?

stomach and duodenal ulcers;

acid-dependent dyspepsia;

ulcerative reflux esophagitis;

peptic ulcers; erosive and ulcerative lesions of the stomach;

erosive and ulcerative formations in the gastric mucosa caused by cirrhosis;

pathological hypersecretory state;

prevention of acid aspiration.

www.astromeridian.ru

How to take Omez correctly for various diseases

Omez is a drug that reduces the secretion of hydrochloric acid. It is indicated for gastritis, pancreatitis, ulcers and other gastrointestinal diseases. Available in different forms: capsules and powders. Not every person knows how to take Omez in order for the drug to be highly effective.

As a rule, the development of stomach diseases begins after gastric secretion sour juice irritating the walls internal organs. The substances included in the drug can inhibit the increase in this acid and thereby cure the patient from serious illnesses.

Actions of the drug

Omez is one of the effective drugs for the treatment of the gastrointestinal tract, characterized by many actions. First of all, during treatment it has the following properties:

1. Antisecretory, due to which hydrochloric acid is blocked, and against the background of this, the secretion of gastric juice is reduced and the symptoms of pain disappear over time.
2. Cytoprotective, protects cells from damage by hydrochloric acid, promoting the healing of ulcers.
3. Bactericidal helps destroy Helicobacter pylori bacteria and other harmful organisms.

In order to remove Helicobacter bacteria from the body, it is recommended to take a comprehensive approach to treatment and take De-nol together with Omez.

Omez is one of the gentle drugs, the advantages of which include the following features that it provides:

• reduces the negative effects of antibiotics;
• does not affect the reaction, therefore it is allowed to be taken by motorists;
• It is well tolerated by people, so it is allowed to take up to two months. Sometimes the course of therapy is even longer;
• for the treatment of advanced cases, a medicine has been released in powder form;
• quickly eliminated from the body;
• used for the prevention of peptic ulcers.

It was described above how the medication works and its advantages over other medications effective for gastrointestinal diseases.

Forms

The drug is available in two forms: in powder form and in capsules, differing in the amount of active substance. Most often, people are treated with Omez D capsules, which are sold in cartons of 10 pieces. They themselves white, but not transparent with a purple top. One capsule contains 10 mg of omeprazole and domperidone.

Omez capsules contain 20 mg of active substance. The package contains 10 transparent capsules with pink caps. The drug is also available in powder form for injection. One ampoule contains 4 mg of the main substance.

Indications for use

You can treat with this drug for any diseases of the gastrointestinal tract: gastritis, reflux, pancreatitis, erosion, ulcers, pulpitis. Some doctors prescribe it to their patients even for the prevention of diseases. But the dosage may differ depending on the type of diagnosis.

Within an hour after taking the stomach pain subsides, and the drug begins to act on secretory function. Maximum time exposure to the drug for 2 hours. After taking the capsule, the effectiveness remains throughout the day. And even after discontinuation of treatment, the drug has an effect for up to three days.

You need to know that capsules do not dissolve in the human stomach; absorption occurs in the intestines. It is for this reason that the effectiveness of taking the medicine occurs in at least an hour.

Complete recovery of the patient occurs after 2 weeks of taking the drug, provided that all the recommendations of the attending physician have been followed.

Dosage

As mentioned above, the dosage primarily depends on the patient’s condition and his diagnosis. Also quite a lot important role The patient’s age, individual characteristics and the presence of contraindications play a role. If severe diseases develop, the drug should be taken in powder form twice a day, 40 mg for invasive administration.

In order to prepare the medicine for injection, you need to do the following:

1. Fill a 5 ml syringe with 5% glucose solution.
2. Add to the bottle with Omez.
3. Shake the contents well.
4. Draw the resulting solution into a new syringe.
5. Add the liquid to a bottle with 100 ml of glucose.
6. Perform the procedure for intravenous administration of medication.

For a disease such as a pancreatic tumor, the dosage of the drug needs to be increased. It is recommended to administer from 60 to 120 mg per day. One of the common questions is the following: how to drink Omez? The answer to this will be given below.

If a person has a normal course of peptic ulcer or gastritis, then treatment can be carried out in capsules. If we are talking about an ulcer, then it will be enough to take the drug twice a day: morning and evening. The first capsule should be drunk after waking up half an hour before meals, and the second after 20:00 in the evening. After taking the medication in the evening, you should not eat, so you need to have dinner before recovery. You need to take one capsule at a time, washing it down with plenty of water.

The tumor can also be treated with capsules, but then they should be taken three times a day. The allowed dose per day is no more than 120 mg. In order to cure the disease that has arisen, you will have to maintain long-term treatment. It is better to consult a doctor about how many months to continue health therapy.

Important! Capsules can only be swallowed; they are not allowed to be crushed, chewed or dissolved. So the effectiveness of the drug will be 0.

For esophageal reflux, most often the course of such treatment lasts one month and after the start of recovery, improvements occur immediately. The method of using the medication is simple, you need to drink two capsules a day. Most often, with such a diagnosis, the patient is prescribed Omez D, which in addition to Omez also contains Domperidone. Similar treatment relevant for heartburn and dyspepsia. But it is worth knowing that Omez D can inhibit the effectiveness of some antibiotics.

For pancreatitis, Omez can only be used as additional treatment, to prevent stomach ulcers. Also, thanks to treatment with this drug, you can reduce abdominal pain and get rid of unpleasant symptoms. Omez should be taken before meals, otherwise it will not have any effect. therapeutic effect.

As mentioned above, Omez is also effective for the prevention of gastritis, ulcers and other gastrointestinal diseases. In this case, it is recommended to drink 1 capsule without a break before going to bed for no longer than 4 months. But it is not necessary to take the drug for so long; you can only be treated at the peak of an exacerbation of the disease.

But even for prevention, you need to drink Omez for at least one month. It must be borne in mind that taking medication for prevention must be started in advance. For example, if an exacerbation of the disease occurs in the fall, then it is recommended to begin recovery from the end of summer.

Omez, the dosage of which was described above, effective remedy for treatment that is approved for use by children and adults over 12 years of age. You should check with your doctor about other contraindications. In some cases, the dosage of the medication may be reduced.

Instructions for use

In order to cure gastrointestinal diseases, the use of Omez and other drugs that contain omeprazole in the complex will be advisable. It has already been said above that you need to take the medicine before meals. However, if you forget to do this, you can swallow the capsule during breakfast, but not after it. You should not increase the dosage indicated by your doctor on your own, as this can be harmful to your health.

Omez, the active ingredient of which is omeprazole, is effective not only for stomach diseases. It is also prescribed for unpleasant symptoms illnesses: belching, heartburn, abdominal pain. Maximum efficiency the drug begins on the fourth day of treatment with Omez. The article talked about how people take omez: before or after meals.

Advice! If for some reason you missed the time of taking the drug, there is no need to restore it, it is recommended to continue treatment, remembering that it can be treated before meals.

The course of treatment with the drug can last from two weeks to two months. Most often, the daily dosage does not exceed 40 mg, but in some cases this dose amount can be increased to 60 mg. But even when the patient has completed therapy with Omez, doctors recommend continuing to take it as a preventive measure, taking 1 capsule per day. However, you should not treat them constantly; after the course of treatment you need to take a break.

Many people, when treating with this medication, wonder whether it is possible to take the drug with other medications. It is possible and even necessary to carry out complex therapy. However, only a doctor should select treatment based on the combination of drugs different groups.

In order to find out how long you can take Omez, you need to consult a doctor, since it all depends on individual characteristics and body structure. But, as a rule, the course of treatment does not exceed 2 months.

If oral administration is not possible or to achieve a quick effect, intravenous administration of omez is used.

Pharmachologic effect:
Omez is an antiulcer agent from the group of proton pump inhibitors. The active ingredient of the product is omeprazole. Omeprazole inhibits stimulated and basal secretion of hydrochloric acid due to specific impact on the enzyme H+/K+-ATPase of parietal cells of the stomach. After internal use, the effect of omeprazole develops quickly within 60 minutes. The effect of the product lasts 24 hours. After discontinuation of omeprazole, restoration of the secretory activity of the exocrine glands of the stomach occurs after 3-5 days. Omeprazole is absorbed quickly from the intestine.

The product contains omez active substance is contained in acid-resistant granules, so the dissolution of the granules is observed only in the intestines. The maximum concentration of the product in the blood plasma is observed after 30-60 minutes. The bioavailability of omeprazole is 40%. 90% of the product binds to plasma proteins. Clearance is 500–600 ml/min. Metabolism of omeprazole occurs in the liver. Eliminated by the kidneys (approximately 80%). Main way metabolism is associated with the enzyme CYP 2C19 - a polymorphic specific isoform (S-mephenyl-thiol-hydroxylase). The main metabolite of the product is hydroxyomeprazole (detected in blood plasma).

In persons with chronic diseases liver with insufficient liver function, the bioavailability of omeza increases to 100%, clearance decreases to 70 ml/min, and the half-life increases to 3 hours. In case of renal failure, the distribution of omeza does not differ from that in healthy volunteers (with a creatinine clearance of 10–62 ml/min). Considering that omeprazole is excreted from the body by the kidneys, then when renal failure Elimination of the product will decrease in direct proportion to creatinine clearance. In elderly people, reduced elimination of omeza is observed with increased bioavailability.

Intravenous administration of omeprazole is accompanied by dose-dependent inhibition of gastric secretion. When intravenous use omeprazole at a dosage of 40 mg, a rapid decrease in secretion of the gastric mucosa is observed, similar to repeated oral administration of the product at a dosage of 20 mg. The degree of inhibition of gastric secretion is approximately 90% throughout the day as in the case intravenous infusion, and with bolus administration of the product. The average half-life of omeprazole following intravenous administration is approximately 40 minutes with a total plasma clearance of 0.3–0.6 L/min.

Omez method of application and dosage:
Intravenous administration for adults with gastroesophageal reflux disease or peptic ulcer of gastric/duodenal localization, it is prescribed as an infusion at a dosage of 40 mg/day. For Zollinger-Ellison syndrome, the initial dosage of omeprazole is 60 mg/day, but more may be prescribed high dose. If the dose of omeprazole per day is more than 60 mg, it can be divided into 2 infusions. For peptic ulcers complicated by bleeding from the gastrointestinal tract, the initial dose of omez is 80 mg/day intravenously (at a rate of 8 mg/hour). Later (from the 3rd to the 21st day) they switch to internal administration of omez at 20 mg/day.

In case of impaired renal function and in gerontological patients, dosage adjustment is not required. In liver failure the greatest daily dose Omeza should be 10-20 mg. The drug for intravenous infusion - omez 40 - is administered over 20-30 minutes. The contents of one bottle should be dissolved in 5% dextrose solution for infusion or 0.9% sodium chloride solution in an amount of 100 ml. The prepared solution is suitable for use throughout the day.

Oral administration of omez. Capsules are taken orally whole: do not chew or break. For reflux esophagitis, peptic ulcer of gastric or duodenal localization, use a dose of 20 mg/day before the morning meal. The course of treatment is 14 days. In case of insufficient therapeutic effect(scarring of the peptic ulcer did not occur) during 2 weeks of treatment, therapy is continued for another 14 days (or until complete scarring). Typically, a peptic ulcer of the duodenum when treated with omez (40 mg/day) heals after 4 weeks, a gastric ulcer or erosive reflux esophagitis is cured after 8 weeks.

For Zollinger-Ellison syndrome, omez is prescribed orally at 60 mg/day. The duration of treatment depends on clinical picture diseases. The maintenance dosage is 20-120 mg/day, which is set at individually doctor. When prescribing omez at a dose greater than 80 mg/day, its dose is divided into 2 applications.
Omez reduces to standard international protocol on eradication of Helicobacter pylori. In case of Helicobacter pylori infection, treatment is carried out according to this protocol.

Omez contraindications:
Allergic reactions to omeprazole or other components of omeza.

Omez side effects:
From the nervous system: dizziness, excessive sweating, headache, agitation, drowsiness, paresthesia, insomnia, blurred vision, hallucinations and depression in patients predisposed to them.
From the gastrointestinal system: abdominal pain, diarrhea, constipation, stomatitis, dry mouth, taste disturbance, temporary increase in transaminase activity and liver tests.
From the outside musculoskeletal system: myalgia, muscle weakness, arthralgia.
Hypersensitivity reactions: urticaria, rash, erythema multiforme.
Others: fever, peripheral edema.

Pregnancy:
Omez is contraindicated for use in pregnant women and breastfeeding women.

Overdose:
A specific antidote is unknown. Exceeding the dose by 160 mg did not lead to symptoms that would threaten the patient's life.

Use with other medications:
Metabolism of the product occurs in hepatocytes with the participation of the cytochrome P450 enzyme system, as a result of which it is prescribed with caution in combination with phenytoin, diazepam, warfarin. With such combinations, omeprazole slows down the elimination of these drugs, which requires a reduction in their dosage.
A combined increase in plasma concentrations of clarithromycin and omeprazole was detected when they were used together.

Release form:
Omez - capsules of 20 mg omeprazole. There are 10 or 30 capsules in a box. Capsules are hard, gelatinous, transparent. The lid is pink, the body is colorless. On both sides of the capsule is the inscription “OMEZ”. The contents of the capsule are almost white or white granules.
Omez 40 is a lyophilized powder for the preparation of a solution for infusion. The bottle contains 40 mg of omeprazole.

Storage conditions:
In a place protected from light and moisture at a temperature not exceeding 25°C.

Omez composition:
Omez capsules
Active substance: omeprazole.
Others: sodium lauryl sulfate, dibasic sodium phosphate, sucrose, purified water.

Lyophilized powder for the preparation of solution for infusion
Active substance: omeprazole.
Others: sodium carbonate anhydrous.

Additionally:
Before starting treatment and subsequently, an endoscopic examination of the stomach and duodenum should be performed. Since omez can neutralize the symptoms of a malignant disease, treatment can delay the diagnosis correct diagnosis.

Attention!
Before using the medication "Omez" You should consult your doctor.
The instructions are provided for informational purposes only. Omez».

Name:

Omez

Pharmacological
action:

Omez – antiulcer agent group of proton pump inhibitors. The active ingredient of the drug is omeprazole. Omeprazole inhibits stimulated and basal secretion of hydrochloric acid due to a specific effect on the enzyme H+/K+-ATPase of the parietal cells of the stomach. After internal use, the effect of omeprazole develops quickly within 60 minutes. The effect of the drug lasts 24 hours. After discontinuation of omeprazole, restoration of the secretory activity of the exocrine glands of the stomach occurs after 3-5 days. Omeprazole is absorbed quickly from the intestine.

The active ingredient in the drug Omez is contained in acid-resistant granules, therefore, the dissolution of granules is observed only in the intestine. The maximum concentration of the drug in the blood plasma is observed after 30-60 minutes. The bioavailability of omeprazole is 40%. 90% of the drug binds to plasma proteins. Clearance is 500–600 ml/min. Metabolism of omeprazole occurs in the liver. Eliminated by the kidneys (approximately 80%). The main metabolic pathway is associated with the enzyme CYP 2C19 - a polymorphic specific isoform (S-mephenyl-thiol-hydroxylase). The main metabolite of the drug is hydroxyomeprazole (detected in blood plasma).

In persons with chronic liver diseases with insufficiency of its function, the bioavailability of omeza increases to 100%, clearance decreases to 70 ml/min, and the half-life increases to 3 hours. In case of renal failure, the distribution of omeza does not differ from that in healthy volunteers (with a creatinine clearance of 10–62 ml/min). Considering that omeprazole is excreted from the body by the kidneys, in case of renal failure, the elimination of the drug will decrease in direct proportion to creatinine clearance. In elderly people, reduced elimination of omeza is observed with increased bioavailability.

Intravenous administration Omeprazole is accompanied by dose-dependent inhibition of gastric secretion. In the case of intravenous use of omeprazole at a dosage of 40 mg, a rapid decrease in secretion of the gastric mucosa is observed, similar to repeated oral administration of the drug at a dosage of 20 mg. The degree of inhibition of gastric secretion is approximately 90% during the day, both in the case of intravenous infusion and bolus administration of the drug. The average half-life of omeprazole after intravenous administration is approximately 40 minutes with a total plasma clearance of 0.3–0.6 L/min.

Indications for
application:

Erosive-ulcerative esophagitis,
- peptic ulcers of the stomach and duodenum,
- ulcerative process in the stomach or duodenum, potentiated by taking non-steroidal anti-inflammatory drugs,
- stress ulcer,
- recurrent peptic ulcers of the gastric or duodenal localization with a tendency to develop complications (anti-relapse therapy),
- Zollinger-Ellison syndrome,
- as part of complex Helicobacter pylori eradication schemes,
- pancreatitis,
- gastroesophageal reflux disease (anti-relapse therapy),
- systemic mastocytosis.

If oral administration is not possible or to achieve a quick effect, intravenous administration of omez is used.

Mode of application:

Intravenous administration for adults for gastroesophageal reflux disease or peptic ulcer of gastric/duodenal localization, it is prescribed as an infusion at a dosage of 40 mg/day. For Zollinger-Ellison syndrome, the initial dosage of omeprazole is 60 mg/day, but a higher dose may be prescribed. If the dose of omeprazole per day is more than 60 mg, it can be divided into 2 infusions. For peptic ulcers complicated by bleeding from the gastrointestinal tract, the initial dose of omez is 80 mg/day intravenously (at a rate of 8 mg/hour). Later (from the 3rd to the 21st day) they switch to internal administration of omez at 20 mg/day.

If kidney function is impaired and in gerontological patients no dosage adjustment is required. In case of liver failure, the maximum daily dose of omez should be 10-20 mg. The drug for intravenous infusion - omez 40 - is administered over 20-30 minutes. The contents of one bottle should be dissolved in 5% dextrose solution for infusion or 0.9% sodium chloride solution in an amount of 100 ml. The prepared solution is suitable for use throughout the day.

Prescription of omez orally. Capsules are taken orally whole: do not chew or break. For reflux esophagitis, peptic ulcer of gastric or duodenal localization, use a dose of 20 mg/day before the morning meal. The course of treatment is 14 days. In case of insufficient therapeutic effect (scarring of the peptic ulcer has not occurred), therapy is continued for another 14 days (or until complete scarring) during 2 weeks of treatment. Typically, a peptic ulcer of the duodenum when treated with omez (40 mg/day) heals after 4 weeks, a gastric ulcer or erosive reflux esophagitis is cured after 8 weeks.

For Zollinger-Ellison syndrome Omez is prescribed orally at 60 mg/day. The duration of treatment depends on the clinical picture of the disease. The maintenance dosage is 20-120 mg/day, which is determined individually by the doctor. When prescribing omez at a dose greater than 80 mg/day, its dose is divided into 2 applications.
Omez brings together the standard international protocol for the eradication of Helicobacter pylori. In case of Helicobacter pylori infection, treatment is carried out according to this protocol.

Side effects:

Side effects are classified depending on the frequency of occurrence: often - 1–10%; sometimes - 0.1–1%; rarely - 0.01–0.1%; very rarely - less than 0.01%, including individual messages.

From the hematopoietic organs: very rarely - leukopenia, thrombocytopenia, agranulocytosis, pancytopenia.
From the digestive system: sometimes - diarrhea, constipation, abdominal pain, nausea, vomiting, flatulence; rarely - increased activity of liver enzymes, taste disturbances; very rarely - dry mouth, stomatitis, in patients with previous serious illness liver - hepatitis (including with jaundice), liver dysfunction.
From the nervous system: in patients with severe concomitant somatic diseases - dizziness, headache, agitation, depression; in patients with previous severe liver disease - encephalopathy.
From the musculoskeletal system: very rarely - arthralgia, myasthenia gravis, myalgia.
From the outside skin : rarely - skin rash and/or itching; in some cases - photosensitivity, exudative erythema multiforme, alopecia.
Allergic reactions: often - urticaria; very rarely - angioedema, fever, bronchospasm, interstitial nephritis and anaphylactic shock.
Others: rarely - gynecomastia, malaise, visual impairment, peripheral edema, increased sweating, formation of gastric glandular cysts during long-term treatment(a consequence of inhibition of hydrochloric acid secretion, is benign, reversible).

Contraindications:

Hypersensitivity;
- pregnancy;
- lactation period;
- childhood.
Carefully: renal and/or liver failure.

Interaction
other medicinal
by other means:

May reduce absorption of ampicillin esters, iron salts, itraconazole and ketoconazole (omeprazole increases the pH of the stomach).

Being an inhibitor cytochrome P450, can increase the concentration and reduce the excretion of diazepam, anticoagulants indirect action(warfarin), phenytoin (drugs that are metabolized in the liver via the CYP2C19 isoenzyme), which in some cases may require reducing the doses of these drugs.

Long-term use omeprazole at a dose of 20 mg 1 time per day in combination with caffeine, theophylline, piroxicam, diclofenac, naproxen, metoprolol, propranolol, ethanol, cyclosporine, lidocaine, quinidine and estradiol did not lead to a change in their plasma concentrations.

Plasma concentrations of omeprazole and clarithromycin blood levels increase during joint oral administration of these drugs, while evidence of interaction of omeprazole with metronidazole and amoxicillin has not been identified.

There was no interaction with concomitantly taken antacids.

Pregnancy:

Omez is contraindicated for use in pregnant women and breastfeeding women.

Overdose:

Symptoms: confusion, blurred vision, drowsiness, dry mouth, headache, nausea, tachycardia, arrhythmia.

Capsules enteric - 1 caps.
active substance: omeprazole 10 mg
Excipients: mannitol - 59/236 mg; crospovidone - 4.5/18 mg; poloxamer (407) - 1.25/5 mg; hypromellose (1828) - 2/8 mg; meglumine - 0.75/3 mg